Dorothe Spillmann
Universitetslektor vid Institutionen för medicinsk biokemi och mikrobiologi; Undervisning, övrigt verksamma
- Telefon:
- 018-471 43 67
- Mobiltelefon:
- 073-934 20 25
- E-post:
- Dorothe.Spillmann@imbim.uu.se
- Besöksadress:
- BMC
Husargatan 3
752 37 UPPSALA - Postadress:
- Box 582
751 23 UPPSALA
- Akademiska meriter:
- PhD, docent
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Publikationer
Senaste publikationer
- Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells (2019)
- Melanoma Cell Adhesion and Migration Is Modulated by the Uronyl 2-O Sulfotransferase (2017)
- A Potential Role for Chondroitin Sulfate/Dermatan Sulfate in Arm Regeneration in Amphiura filiformis. (2017)
- Chondroitinase AC (2016)
- Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma (2016)
Alla publikationer
Artiklar
- Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells (2019)
- Melanoma Cell Adhesion and Migration Is Modulated by the Uronyl 2-O Sulfotransferase (2017)
- A Potential Role for Chondroitin Sulfate/Dermatan Sulfate in Arm Regeneration in Amphiura filiformis. (2017)
- Chondroitinase AC (2016)
- Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma (2016)
- Uronyl 2-O sulfotransferase potentiates Fgf2-induced cell migration (2015)
- A visualizable chain-terminating inhibitor of glycosaminoglycan biosynthesis in developing zebrafish (2014)
- An automated mass spectrometry-based screening method for analysis of sulfated glycosaminoglycans (2014)
- HS3ST2 modulates breast cancer cell invasiveness and chemosensitivity via MAP kinase- and TCF7L2/TCF4-dependent regulation of protease and cadherin expression (2014)
- HS3ST2 modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression (2014)
- Brittlestars contain highly sulfated chondroitin sulfates/dermatan sulfates that promote fibroblast growth factor 2-induced cell signaling (2014)
- Characterization of Glycosaminoglycan (GAG) Sulfatases from the Human Gut Symbiont Bacteroides thetaiotaomicron Reveals the First GAG-specific Bacterial Endosulfatase (2014)
- MicroRNA-24 Suppression of N-Deacetylase/N-Sulfotransferase-1 (NDST1) Reduces Endothelial Cell Responsiveness to Vascular Endothelial Growth Factor A (VEGFA) (2013)
- Specific sulfation patterns in heparan sulfate promote a proinvasive phenotype of breast cancer cells via upregulation of Wnt and MAPK signaling (2013)
- HS3ST2 overexpression increases invasiveness of MDA-MB 231 breast cancer cells via up-regulation of protease expression and MAPK signalling (2013)
- The Mutual Impact of Syndecan-1 and Its Glycosaminoglycan Chains-A Multivariable Puzzle (2012)
- On the Roles and Regulation of Chondroitin Sulfate and Heparan Sulfate in Zebrafish Pharyngeal Cartilage Morphogenesis (2012)
- HS3ST2 overexpression increases invasiveness of MDA-MB-231 breast cancercells via up-regulation of protease expression and MAPK signaling (2012)
- Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis (2012)
- Structural Basis of Oligosaccharide Receptor Recognition by Human Papillomavirus (2011)
- Heparan Sulfate Domain Organization and Sulfation Modulate FGF-induced Cell Signaling (2010)
- Serglycin-independent release of active mast cell proteases in response to Toxoplasma gondii infection (2010)
- The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease (2010)
- Structural basis for the growth factor activity of human adenosine deaminase ADA2 (2010)
- Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression (2009)
- Heparin/heparan sulfate biosynthesis (2008)
- Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR (2008)
- Changes in heparan sulfate are associated with delayed wound repair, altered cell migration, adhesion and contractility in the galactosyltransferase I (beta4GalT-7) deficient form of Ehlers-Danlos syndrome. (2008)
- Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development (2007)
- Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate (2007)
- Surface-exposed amino acid residues of HPV16 L1 protein mediating interaction with cell surface heparan sulfate (2007)
- Characterization of anti-heparan sulfate phage display antibodies AO4B08 and HS4E4 (2007)
- Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin. (2006)
- Overexpression of Heparan Sulfate 6-O-sulfotransferases in Human Embryonic Kidney 293 Cells Results in Increased N-Acetylglucosaminyl 6-O-sulfation (2006)
- Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation. (2006)
- Heparan sulfate-related oligosaccharides in ternary complex formation with fibroblast growth factors 1 and 2 and their receptors (2006)
- Interactions between heparan sulfate and proteins (2006)
- Heparan sulphate requirement in platelet-derived growth factor B-mediated pericyte recruitment (2006)
- Isolation and characterization of low sulfated heparan sulfate sequences with affinity for lipoprotein lipase (2006)
- 3-O-sulfated oligosaccharide structures are recognized by anti-heparan sulfate antibody HS4C3. (2006)
- 3-O sulfated oligosaccharide structures are recognized by anti-heparan sulfate antibody HS4C3 (2006)
- Release of sequestered malaria parasites upon injection of a glycosaminoglycan (2006)
- Heparan sulfate structure in mice with genetically modified heparan sulfate production. (2004)
- Heparan sulphate identified on human erythrocytes (2004)
- Heparan sulfate on endothelial cells mediates the binding of Plasmodium falciparum-infected erythrocytes via the DBL1alpha domain of PfEMP1 (2003)
- Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function (2002)
- Heparin amplifies Platelet-derived growth factor (PDGF)-BB-induced PDGF alfa receptor but not PDGF beta receptor tyrosine phosphorylation in heparan sulfate-deficient cells (2002)
- Testosterone-induced growth of S115 mouse mammary tumor cells is dependent on heparan sulfate (2001)
- Structural requirements and mechanism for heparin-induced activation of a recombinant mouse mast cell tryptase, mouse mast cell protease-6 (2001)
- Heparan sulfate (2001)
- The duffy-binding-like domain 1 of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a heparan sulfate ligand that requires 12 mers for binding (2000)
- The amino-terminal part of PRELP binds to heparin and heparan sulfate (2000)
- Characterisation of the chondroitin sulphate of Saimiri brain microvascular endothelial cells involved in Plasmodium falciparum cytoadhesion (2000)
- Glycosaminoglycan sulfation requirements for respiratory syncytial virus infection (2000)
- Sticky sugars attract malaria to the fetus (2000)
- Role of glycans in Plasmodium falciparum infection (1999)
- Plasmodium falciparum: molecular background to strain-specific rosettedisruption by glycosaminoglycans and sulfated glycoconjugates (1999)
- Erythrocyte Glycans as Plasmodium falciparum Rosetting Receptors (1999)
- Characterization of a neutophil surfacer glycosaminoglycan responsible for binding of platelet factor 4 (1999)
- Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides (1999)
- Erythrocyte glycans as Plasmodium Falciparum rosetting receptors (1998)
- Defining the interleukin-8-binding domain of heparan sulfate (1998)
- Interaction between pseudorabies virus and heparin/heparan sulfate (1998)
- Heparan sulfate and viral tropism (1997)
- Heparan sulfate and viral tropism (1997)
- Characterization of heparin and heparan sulfate domains binding to the long splice variant of platelet-derived growth factor A chain (1997)
- Structural requirement of heparan sulfate for interaction with herpes simplex virus type 1 virions and isolated glycoprotein C (1997)
- Selective loss of cerebral keratan sulfate in Alzheimer's disease (1996)
- Carbohydrate-carbohydrate Interactions in Adhesion (1996)
- Mode of Interaction Between Pseudorabies Virus and Heparan Sulfate/Heparin (1996)
- What defines specificity of chemokine-glycosaminoglycan interaction ? (1995)
- Characterization of a Novel Sulfated Carbohydrate Unit Implicated in the CarbohydrateCarbohydrate-mediated Cell Aggregation of the Marine Sponge Microciona prolifera (1995)
- More to "heparin" than anticoagulation (1994)
- Carbohydrates in cellular recognition (1994)
- Identification of a major poly-N-acetyllactosamine-containing cell-surface glycoprotein of mouse teratocarcinoma cells (1994)
- Characterization of a novel pyruvylated carbohydrate unit implicated in the cell aggregation of the marine sponge Microciona prolifera (1993)
- Specific labeling of cell surface poly-N-acetyllactosamine glycans (1989)
- Poly-N-acetyllactosamine glycans of cellular glycoproteins (1987)
- Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetyl glucosaminyl 6-O-sulfation
- Heparan sulfate-related oligosaccharides modulate cell signaling induced by fibroblast growth factor 2
- Binding of FGF2 to size-fractionated heparan sulfate from porcine tissues
- Heparan sulfate biosynthesis: PAPS regulates NDST-mediated formation of N-sulfated domains
- Binding of histidine-rich glycoprotein and FGF-2 to size-fractionated heparan sulfate from porcine tissues