Ulf Landegren

A ligase-based toolbox for research and diagnostics in molecular medicine

Landegren, Ulf

Ingår i Nucleic Acids Research, 2026

• DOI för A ligase-based toolbox for research and diagnostics in molecular medicine
• Ladda ner fulltext (pdf) av A ligase-based toolbox for research and diagnostics in molecular medicine

A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

Ikebuchi, Ryoyo; Lu, Xi; Bouri, Dimitra; Svintytska, Valeriia et al.

Ingår i PLOS ONE, 2025

• DOI för A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification
• Ladda ner fulltext (pdf) av A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

An international perspective on the future of systemic sclerosis research

Abraham, David J.; Black, Carol M.; Denton, Christopher P.; Distler, Jörg H. W. et al.

Ingår i Nature Reviews Rheumatology, s. 174-187, 2025

• DOI för An international perspective on the future of systemic sclerosis research

Nanoplasmonic Rapid Antimicrobial-Resistance Point-of-Care Identification Device: RAPIDx

Lee, Jong-Hwan; Song, Jihwan; Hong, SoonGweon; Kim, Yun et al.

Ingår i Advanced Healthcare Materials, 2025

• DOI för Nanoplasmonic Rapid Antimicrobial-Resistance Point-of-Care Identification Device: RAPIDx

Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)

Wang, Mengqi; Kamali-Moghaddam, Masood; Löf, Liza; Fernandez, Matilde Cortabarria et al.

Ingår i Scientific Reports, 2024

• DOI för Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)
• Ladda ner fulltext (pdf) av Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)

A ligase-based toolbox for research and diagnostics in molecular medicine

Landegren, Ulf

Ingår i Nucleic Acids Research, 2026

• DOI för A ligase-based toolbox for research and diagnostics in molecular medicine
• Ladda ner fulltext (pdf) av A ligase-based toolbox for research and diagnostics in molecular medicine

A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

Ikebuchi, Ryoyo; Lu, Xi; Bouri, Dimitra; Svintytska, Valeriia et al.

Ingår i PLOS ONE, 2025

• DOI för A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification
• Ladda ner fulltext (pdf) av A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification

Nanoplasmonic Rapid Antimicrobial-Resistance Point-of-Care Identification Device: RAPIDx

Lee, Jong-Hwan; Song, Jihwan; Hong, SoonGweon; Kim, Yun et al.

Ingår i Advanced Healthcare Materials, 2025

• DOI för Nanoplasmonic Rapid Antimicrobial-Resistance Point-of-Care Identification Device: RAPIDx

Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)

Wang, Mengqi; Kamali-Moghaddam, Masood; Löf, Liza; Fernandez, Matilde Cortabarria et al.

Ingår i Scientific Reports, 2024

• DOI för Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)
• Ladda ner fulltext (pdf) av Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA)

Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma

Sandberg, Emma; Nunes, Luís; Edqvist, Per-Henrik; Mathot, Lucy et al.

Ingår i Cancers, 2024

• DOI för Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma
• Ladda ner fulltext (pdf) av Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma

Managing leukemia patients via liquid biopsy and super rolling circle amplification (superRCA)

Robelius, Anna; Chen, Lei; Amini, Rose-Marie; Cavelier, Lucia et al.

Ingår i Journal of Internal Medicine, s. 228-237, 2023

• DOI för Managing leukemia patients via liquid biopsy and super rolling circle amplification (superRCA)

Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays

Chen, Lei; Eriksson, Anna; Weström, Simone; Pandzic, Tatjana et al.

Ingår i Nature Communications, 2022

• DOI för Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays
• Ladda ner fulltext (pdf) av Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays

Detection of SARS-CoV-2 antibodies in serum and dried blood spot samples of vaccinated individuals using a sensitive homogeneous proximity extension assay

Zhao, Hongxing; Wang, Mengqi; Muthelo, Phathutshedzo; Löf, Liza et al.

Ingår i New Biotechnology, s. 139-148, 2022

• DOI för Detection of SARS-CoV-2 antibodies in serum and dried blood spot samples of vaccinated individuals using a sensitive homogeneous proximity extension assay
• Ladda ner fulltext (pdf) av Detection of SARS-CoV-2 antibodies in serum and dried blood spot samples of vaccinated individuals using a sensitive homogeneous proximity extension assay

Surface protein profiling of prostate-derived extracellular vesicles by mass spectrometry and proximity assays

Doulabi, Ehsan Manouchehri; Fredolini, Claudia; Gallini, Radiosa; Löf, Liza et al.

Ingår i Communications Biology, 2022

• DOI för Surface protein profiling of prostate-derived extracellular vesicles by mass spectrometry and proximity assays
• Ladda ner fulltext (pdf) av Surface protein profiling of prostate-derived extracellular vesicles by mass spectrometry and proximity assays

Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils et al.

Ingår i Nucleic Acids Research, 2022

• DOI för Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ
• Ladda ner fulltext (pdf) av Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ

Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Al-Amin, Rasel Abdullah; Muthelo, Phathutshedzo M.; Abdurakhmanov, Eldar; Vincke, Cecile et al.

Ingår i Analytical Chemistry, s. 10054-10061, 2022

• DOI för Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents
• Ladda ner fulltext (pdf) av Sensitive protein detection using site-specifically oligonucleotide-conjugated nanobody reagents

Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level

Lönn, Peter; Al-Amin, Abdullah; Doulabi, Ehsan Manouchehri; Heldin, Johan et al.

Ingår i Communications Biology, 2021

• DOI för Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level
• Ladda ner fulltext (pdf) av Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level

Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout

Al-Amin, Rasel A.; Gallant, Caroline J.; Muthelo, Phathutshedzo M.; Landegren, Ulf

Ingår i Analytical Chemistry, s. 10999-11009, 2021

• DOI för Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout
• Ladda ner fulltext (pdf) av Sensitive Measurement of Drug-Target Engagement by a Cellular Thermal Shift Assay with Multiplex Proximity Extension Readout

Human proteins incorporated into tick-borne encephalitis virus revealed by in situ proximity ligation

Ikebuchi, Ryoyo; Isaac, Alfred W.; Yoshii, Kentaro; Doulabi, Ehsan Manouchehri et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 714-719, 2020

• DOI för Human proteins incorporated into tick-borne encephalitis virus revealed by in situ proximity ligation
• Ladda ner fulltext (pdf) av Human proteins incorporated into tick-borne encephalitis virus revealed by in situ proximity ligation

A multiplex platform for digital measurement of circular DNA reaction products

Björkesten, Johan; Patil, Sourabh; Fredolini, Claudia; Lönn, Peter et al.

Ingår i Nucleic Acids Research, 2020

• DOI för A multiplex platform for digital measurement of circular DNA reaction products

Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

Lindskog, Cecilia; Backman, Max; Zieba, Agata; Asplund, Anna et al.

Ingår i Journal of Histochemistry and Cytochemistry, s. 515-529, 2020

• DOI för Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

A compendium on single-cell analysis for the curious

Gallant, Caroline J.; Landegren, Ulf

Ingår i The FEBS Journal, s. 1442-1444, 2019

• DOI för A compendium on single-cell analysis for the curious

Profiling surface proteins on individual exosomes using a proximity barcoding assay

Wu, Di; Yan, Junhong; Shen, Xia; Sun, Yu et al.

Ingår i Nature Communications, 2019

• DOI för Profiling surface proteins on individual exosomes using a proximity barcoding assay
• Ladda ner fulltext (pdf) av Profiling surface proteins on individual exosomes using a proximity barcoding assay

Protein profiling of fine-needle aspirates reveals subtype-associated immune signatures and involvement of chemokines in breast cancer

Franzen, Bo; Alexeyenko, Andrey; Kamali-Moghaddam, Masood; Hatschek, Thomas et al.

Ingår i Molecular Oncology, s. 376-391, 2019

• DOI för Protein profiling of fine-needle aspirates reveals subtype-associated immune signatures and involvement of chemokines in breast cancer
• Ladda ner fulltext (pdf) av Protein profiling of fine-needle aspirates reveals subtype-associated immune signatures and involvement of chemokines in breast cancer

Next wave advances in single-cell analyses

Herr, Amy E.; Kitamori, Takehiko; Landegren, Ulf; Kamali-Moghaddam, Masood

Ingår i The Analyst, s. 735-737, 2019

• DOI för Next wave advances in single-cell analyses

Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes

Klaesson, Axel; Grannas, Karin; Ebai, Tonge; Heldin, Johan et al.

Ingår i Scientific Reports, 2018

• DOI för Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes
• Ladda ner fulltext (pdf) av Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes

Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.

Lindblom, Rickard P F; Shen, Qiujin; Axén, Sofie; Landegren, Ulf et al.

Ingår i Journal of Cardiovascular Translational Research, s. 503-516, 2018

• DOI för Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.

Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays

Shen, Qiujin; Björkesten, Johan; Galli, Joakim; Ekman, Daniel et al.

Ingår i Clinical Chemistry and Laboratory Medicine, s. 582-594, 2018

• DOI för Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays

A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions

Franzen, Bo; Kamali-Moghaddam, Masood; Alexeyenko, Andrey; Hatschek, Thomas et al.

Ingår i Molecular Oncology, s. 1415-1428, 2018

• DOI för A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions
• Ladda ner fulltext (pdf) av A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Zieba, Agata; Ponten, Fredrik; Uhlen, Mathias; Landegren, Ulf

Ingår i Modern Pathology, s. 253-263, 2018

• DOI för In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

Schuette, Moritz; Risch, Thomas; Abdavi-Azar, Nilofar; Boehnke, Karsten et al.

Ingår i Nature Communications, 2017

• DOI för Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
• Ladda ner fulltext (pdf) av Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan, Narendra; Yan, Junhong; Boge, Annegret; Scrivener, Elaine et al.

Ingår i Scientific Reports, 2017

• DOI för Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation
• Ladda ner fulltext (pdf) av Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia

Löf, Liza; Arngården, Linda; Olsson-Strömberg, Ulla; Siart, Benjamin et al.

Ingår i Scientific Reports, s. 1-9, 2017

• DOI för Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia
• Ladda ner fulltext (pdf) av Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Larssen, Pia; Wik, Lotta; Czarnewski, Paulo; Eldh, Maria et al.

Ingår i Molecular & Cellular Proteomics, 2017

• DOI för Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Stability of Proteins in Dried Blood Spot Biobanks.

Björkesten, Johan; Enroth, Stefan; Shen, Qiujin; Wik, Lotta et al.

Ingår i Molecular & Cellular Proteomics, s. 1286-1296, 2017

• DOI för Stability of Proteins in Dried Blood Spot Biobanks.
• Ladda ner fulltext (pdf) av Stability of Proteins in Dried Blood Spot Biobanks.

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay

Larssen, Pia; Wik, Lotta; Czarnewski, Paulo; Eldh, Maria et al.

Ingår i Molecular & Cellular Proteomics, s. 502-511, 2017

• DOI för Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assay

Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification

Ebai, Tonge; de Oliveira, Felipe Marques Souza; Löf, Liza; Wik, Lotta et al.

Ingår i Clinical Chemistry, s. 1497-1505, 2017

• DOI för Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Ingår i Cell Reports, s. 380-389, 2016

• DOI för Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
• Ladda ner fulltext (pdf) av Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Genshaft, Alex S.; Li, Shuqiang; Gallant, Caroline J.; Darmanis, Spyros et al.

Ingår i Genome Biology, 2016

• DOI för Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction
• Ladda ner fulltext (pdf) av Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout

Löf, Liza; Ebai, Tonge; Dubois, Louise; Wik, Lotta et al.

Ingår i Scientific Reports, 2016

• DOI för Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout
• Ladda ner fulltext (pdf) av Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout

Single Chain Antibodies as Tools to Study transforming growth factor--Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

Blokzijl, Andries; Zieba, Agata; Hust, Michael; Schirrmann, Thomas et al.

Ingår i Molecular & Cellular Proteomics, s. 1848-1856, 2016

• DOI för Single Chain Antibodies as Tools to Study transforming growth factor--Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens

Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay

Blokzijl, Andries; Chen, Lei; Gustafsdottir, Sigrun M.; Vuu, Jimmy et al.

Ingår i PLOS ONE, 2016

• DOI för Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay
• Ladda ner fulltext (pdf) av Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay

Detection of prognostic biomarkers with solid-phase proximity ligation assay in patients with colorectal cancer

Ghanipour, Lana; Darmanis, Spyros; Landegren, Ulf; Glimelius, Bengt et al.

Ingår i Translational Oncology, s. 251-255, 2016

• DOI för Detection of prognostic biomarkers with solid-phase proximity ligation assay in patients with colorectal cancer
• Ladda ner fulltext (pdf) av Detection of prognostic biomarkers with solid-phase proximity ligation assay in patients with colorectal cancer

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind, Anne-Li; Yu, Di; Freyhult, Eva; Bodolea, Constantin et al.

Ingår i PLOS ONE, 2016

• DOI för A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
• Ladda ner fulltext (pdf) av A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

AFFINOMICS and the prospects for large-scale protein analyses

Landegren, Ulf

Ingår i New Biotechnology, s. 491-493, 2016

• DOI för AFFINOMICS and the prospects for large-scale protein analyses

Pla Flow; A Flow Cytometry-Based Assay For Detection Of Bcr-Abl Fusion Protein In Blood Cells From Cml Patients

Löf, Liza; Olsson-Strömberg, Ulla; Landegren, Ulf; Kamali-Moghaddam, Masood

Ingår i Haematologica, s. 457-458, 2016

Clinical Relevance Of Recurrent Allele-Specific Recombination Expressing The Wnt10Bivs1 Allele Variant In Acute Myeloid Leukemia

Beghini, A.; Lazzaroni, F.; Del Giacco, L.; Söderberg, Ola et al.

Ingår i Haematologica, s. 668-669, 2016

Visualization of Borna Disease Virus Protein Interactions with Host Proteins using in situ Proximity Ligation Assay

Johansson Wensman, Jonas; Leuchowius, Karl-Johan; Yan, Jiting; Berg, Anna-Lena et al.

Ingår i British journal of virology, s. 11-23, 2016

• DOI för Visualization of Borna Disease Virus Protein Interactions with Host Proteins using in situ Proximity Ligation Assay

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome

Gu, Gucci Jijuan; Friedman, Mikaela; Ren, Ping; Torn, Carina et al.

Ingår i Scientific Reports, 2015

• DOI för Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome
• Ladda ner fulltext (pdf) av Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome

BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres

van Ommen, Gert-Jan B; Törnwall, Outi; Bréchot, Christian; Dagher, Georges et al.

Ingår i European Journal of Human Genetics, s. 893-900, 2015

• DOI för BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres

The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.

Galli, Joakim; Oelrich, Johan; Taussig, Michael J; Andreasson, Ulrika et al.

Ingår i Nucleic Acids Research, 2015

• DOI för The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.

CK1 delta restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1 alpha/ARNT complex formation

Kourti, Maria; Ikonomou, Georgia; Giakoumakis, Nikolaos-Nikiforos; Rapsomaniki, Maria Anna et al.

Ingår i Cellular Signalling, s. 1129-1140, 2015

• DOI för CK1 delta restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1 alpha/ARNT complex formation
• Ladda ner fulltext (pdf) av CK1 delta restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1 alpha/ARNT complex formation

FLOW CYTOMETRY-BASED ASSAY FOR DETECTION OF BCR-ABL FUSION PROTEIN IN BLOOD CELLS FROM CML PATIENTS

Löf, Liza; Olsson-Strömberg, Ulla; Landegren, Ulf; Kamali-Moghaddam, Masood

Ingår i Haematologica, s. 694-695, 2015

Parallel protein detection by solid-phase proximity ligation assay with real-time PCR or sequencing

Ebai, Tonge; Kamali-Moghaddam, Masood; Landegren, Ulf

Ingår i Current Protocol in Molecular Biology, 2015

• DOI för Parallel protein detection by solid-phase proximity ligation assay with real-time PCR or sequencing

Öppenheten förstör chansen till patent

Arvidsson, Per I.; Domeij, Bengt; Hansson, Mats G.; Landegren, Ulf et al.

Ingår i Svenska dagbladet, 2015

A Universal Approach to Prepare Reagents for DNA-Assisted Protein Analysis

Yan, Junhong; Gu, Gucci Jijuan; Jost, Christian; Hammond, Maria et al.

Ingår i PLOS ONE, 2014

• DOI för A Universal Approach to Prepare Reagents for DNA-Assisted Protein Analysis
• Ladda ner fulltext (pdf) av A Universal Approach to Prepare Reagents for DNA-Assisted Protein Analysis

Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies

Zatloukal, Bernhard; Kufferath, Iris; Thueringer, Andrea; Landegren, Ulf et al.

Ingår i PLOS ONE, 2014

• DOI för Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies
• Ladda ner fulltext (pdf) av Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies

Sensitive detection of aggregated prion protein via proximity ligation

Hammond, Maria; Wik, Lotta; Deslys, Jean-Philippe; Comoy, Emmanuel et al.

Ingår i Prion, s. 261-265, 2014

• DOI för Sensitive detection of aggregated prion protein via proximity ligation

Role of Individual MARK Isoforms in Phosphorylation of Tau at Ser²⁶² in Alzheimer's Disease

Gu, Gucci Jijuan; Lund, Harald; Wu, Di; Blokzijl, Andries et al.

Ingår i Neuromolecular medicine, s. 458-469, 2013

• DOI för Role of Individual MARK Isoforms in Phosphorylation of Tau at Ser²⁶² in Alzheimer's Disease

Improving Precision of Proximity Ligation Assay by Amplified Single Molecule Detection

Ke, Rongqin; Nong, Rachel Yuan; Fredriksson, Simon; Landegren, Ulf et al.

Ingår i PLOS ONE, 2013

• DOI för Improving Precision of Proximity Ligation Assay by Amplified Single Molecule Detection
• Ladda ner fulltext (pdf) av Improving Precision of Proximity Ligation Assay by Amplified Single Molecule Detection

Parallel Visualization of Multiple Protein Complexes in Individual Cells in Tumor Tissue

Leuchowius, Karl-Johan; Clausson, Carl-Magnus; Grannas, Karin; Erbilgin, Yücel et al.

Ingår i Molecular & Cellular Proteomics, s. 1563-1571, 2013

• DOI för Parallel Visualization of Multiple Protein Complexes in Individual Cells in Tumor Tissue

Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

Sundqvist, Anders; Zieba, Agata; Vasilaki, Eleftheria; Herrera Hidalgo, Carmen et al.

Ingår i Oncogene, s. 3606-3615, 2013

• DOI för Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation

Gu, Gucci Jijuan; Friedman, Mikaela; Jost, Christian; Johnsson, Kai et al.

Ingår i New Biotechnology, s. 144-152, 2013

• DOI för Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation

Elevated MARK2-Dependent Phosphorylation of Tau in Alzheimer's Disease

Gu, Gucci Jijuan; Wu, Di; Lund, Harald; Sunnemark, Dan et al.

Ingår i Journal of Alzheimer's Disease, s. 699-713, 2013

• DOI för Elevated MARK2-Dependent Phosphorylation of Tau in Alzheimer's Disease

Workshop on laboratory protocol standards for the molecular methods database

Klingström, Tomas; Soldatova, Larissa; Stevens, Robert; Roos, Erik et al.

Ingår i New Biotechnology, s. 109-113, 2013

• DOI för Workshop on laboratory protocol standards for the molecular methods database

Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing

Nong, Rachel Yuan; Wu, Di; Yan, Junhong; Hammond, Maria et al.

Ingår i Nature Protocols, s. 1234-1248, 2013

• DOI för Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing
• Ladda ner fulltext (pdf) av Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing

Multiplex protein detection with DNA readout via mass spectrometry

Flanigon, James; Kamali-Moghaddam, Masood; Burbulis, Ian; Annink, Carla et al.

Ingår i New Biotechnology, s. 153-158, 2013

• DOI för Multiplex protein detection with DNA readout via mass spectrometry

Offshoots of the ESF functional genomics programme

Landegren, Ulf

Ingår i New Biotechnology, s. 296-298, 2013

• DOI för Offshoots of the ESF functional genomics programme

Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Giandomenico, Valeria; Modlin, Irvin M.; Pontén, Fredrik; Nilsson, Mats et al.

Ingår i Neuroendocrinology, s. 16-30, 2013

• DOI för Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Profiling cellular protein complexes by proximity ligation with dual tag microarray readout

Hammond, Maria; Nong, Rachel Yuan; Ericsson, Olle; Pardali, Katerina et al.

Ingår i PLOS ONE, 2012

• DOI för Profiling cellular protein complexes by proximity ligation with dual tag microarray readout
• Ladda ner fulltext (pdf) av Profiling cellular protein complexes by proximity ligation with dual tag microarray readout

Visualising individual sequence-specific protein-DNA interactions in situ

Weibrecht, Irene; Gavrilovic, Milan; Lindbom, Lena; Landegren, Ulf et al.

Ingår i New Biotechnology, s. 589-598, 2012

• DOI för Visualising individual sequence-specific protein-DNA interactions in situ

Opportunities for sensitive plasma proteome analysis

Landegren, Ulf; Vänelid, Johan; Hammond, Maria; Nong, Rachel Yuan et al.

Ingår i Analytical Chemistry, s. 1824-1830, 2012

• DOI för Opportunities for sensitive plasma proteome analysis

Molecular tools for sensitive detection of microvesicles as biomarkers

Kamali-Moghaddam, Masood; Yan, Junhong; Wu, Di; Löf, Liza et al.

Ingår i Protein Science, s. 164-164, 2012

• DOI för Molecular tools for sensitive detection of microvesicles as biomarkers

PCR-Based Multiparametric Assays in Single Cells.

Darmanis, Spyros; Gallant, Caroline; Landegren, Ulf

Ingår i Clinical Chemistry, s. 1618-1619, 2012

• DOI för PCR-Based Multiparametric Assays in Single Cells.

Intercellular variation in signaling through the TGF-β pathway and its relation to cell densityand cell cycle phase

Zieba, Agata; Pardali, Katerina; Söderberg, Ola; Lindbom, Lena et al.

Ingår i Molecular & Cellular Proteomics, 2012

• DOI för Intercellular variation in signaling through the TGF-β pathway and its relation to cell densityand cell cycle phase

Contributions of the EMERALD project to assessing and improving microarray data quality

Beisvåg, Vidar; Kauffmann, Audrey; Malone, James; Foy, Carole et al.

Ingår i BioTechniques, s. 27-31, 2011

• DOI för Contributions of the EMERALD project to assessing and improving microarray data quality

Comprehensive catalog of European biobanks

Wichmann, H-Erich; Kuhn, Klaus A.; Waldenberger, Melanie; Schmelcher, Dominik et al.

Ingår i Nature Biotechnology, s. 795-797, 2011

ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Darmanis, Spyros; Nong, Rachel Yuan; Vänelid, Johan; Siegbahn, Agneta et al.

Ingår i PLOS ONE, 2011

• DOI för ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing

Increasing the dynamic range of in situ PLA

Clausson, Carl-Magnus; Allalou, Amin; Weibrecht, Irene; Mahmoudi, Salah et al.

Ingår i Nature Methods, s. 892-893, 2011

• DOI för Increasing the dynamic range of in situ PLA

Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer

Tavoosidana, Gholamreza; Ronquist, Gunnar; Darmanis, Spyros; Yan, Junhong et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 8809-8814, 2011

• DOI för Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer

Western Blotting via Proximity Ligation for High Performance Protein Analysis

Liu, Yanling; Gu, Jijuan; Hagner-McWhirter, Asa; Sathiyanarayanan, Poojahrau et al.

Ingår i Molecular & Cellular Proteomics, 2011

• DOI för Western Blotting via Proximity Ligation for High Performance Protein Analysis

Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection

Zieba, Agata; Wählby, Carolina; Hjelm, Fredrik; Jordan, Lee et al.

Ingår i Clinical Chemistry, s. 99-110, 2010

• DOI för Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection

Sensitive detection of A beta protofibrils by proximity ligation: relevance for Alzheimer's disease

Kamali-Moghaddam, Masood; Ekholm Pettersson, Frida; Wu, Di; Englund, Hillevi et al.

Ingår i BMC Neuroscience, s. 124, 2010

• DOI för Sensitive detection of A beta protofibrils by proximity ligation: relevance for Alzheimer's disease

Sensitive plasma protein analysis by microparticle-based proximity ligation assays

Darmanis, Spyros; Nong, Rachel Yuan; Hammond, Maria; Gu, Jijuan et al.

Ingår i Molecular & Cellular Proteomics, s. 327-335, 2010

• DOI för Sensitive plasma protein analysis by microparticle-based proximity ligation assays

High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation

Leuchowius, Karl-Johan; Jarvius, Malin; Wickström, Malin; Rickardson, Linda et al.

Ingår i Molecular & Cellular Proteomics, s. 178-183, 2010

• DOI för High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation

Single molecule analysis of combinatorial splicing

Conze, Tim; Göransson, Jenny; Razzaghian, Hamidreza; Ericsson, Olle et al.

Ingår i Nucleic Acids Research, 2010

• DOI för Single molecule analysis of combinatorial splicing

Novel means of viral antigen identification: Improved detection of avian influenza viruses by proximity ligation

Schlingemann, Joerg; Leijon, Mikael; Yacoub, Alia; Schlingemann, Heidi et al.

Ingår i Journal of Virological Methods, s. 116-122, 2010

• DOI för Novel means of viral antigen identification: Improved detection of avian influenza viruses by proximity ligation

A Community Standard Format for the Representation of Protein Affinity Reagents

Gloriam, David E.; Orchard, Sandra; Bertinetti, Daniela; Björling, Erik et al.

Ingår i Molecular & Cellular Proteomics, s. 1-10, 2010

• DOI för A Community Standard Format for the Representation of Protein Affinity Reagents

MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas

Conze, Tim; Carvalho, Ana Sofia; Landegren, Ulf; Almeida, Raquel et al.

Ingår i Glycobiology, s. 199-206, 2010

• DOI för MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas

Glycosylases and AP-cleaving enzymes as a general tool for probe-directed cleavage of ssDNA targets

Howell, W. Mathias; Grundberg, Ida; Faryna, Marta; Landegren, Ulf et al.

Ingår i Nucleic Acids Research, 2010

• DOI för Glycosylases and AP-cleaving enzymes as a general tool for probe-directed cleavage of ssDNA targets

Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

Leuchowius, Karl-Johan; Weibrecht, Irene; Landegren, Ulf; Gedda, Lars et al.

Ingår i Cytometry: Part A, s. 833-839, 2009

• DOI för Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

Multiplex and quantifiable detection of nucleic acid from pathogenic fungi using padlock probes, generic real time PCR and specific suspension array readout

Eriksson, Ronnie; Jobs, Magnus; Ekstrand, Charlotta; Ullberg, Måns et al.

Ingår i Journal of Microbiological Methods, s. 195-202, 2009

• DOI för Multiplex and quantifiable detection of nucleic acid from pathogenic fungi using padlock probes, generic real time PCR and specific suspension array readout

Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

Massinen, Satu; Tammimies, Kristiina; Tapia-Páez, Isabel; Matsson, Hans et al.

Ingår i Human Molecular Genetics, s. 2802-2812, 2009

• DOI för Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

Selective amplification of mutant DNA: mutations come to light in melting DNA

Landegren, Ulf

Ingår i Human Mutation, 2009

• DOI för Selective amplification of mutant DNA: mutations come to light in melting DNA

Proximity ligation measurement of the complex between prostate specific antigen and alpha1-protease inhibitor

Zhu, Lei; Koistinen, Hannu; Landegren, Ulf; Stenman, Ulf-Håkan

Ingår i Clinical Chemistry, s. 1665-1671, 2009

• DOI för Proximity ligation measurement of the complex between prostate specific antigen and alpha1-protease inhibitor

Estrogen receptor alpha gene polymorphism and endometrial cancer risk: a case-control study

Wedrén, Sara; Lovmar, Lovisa; Humphreys, Keith; Magnusson, Cecilia et al.

Ingår i BMC Cancer, s. 322, 2008

• DOI för Estrogen receptor alpha gene polymorphism and endometrial cancer risk: a case-control study

Interferon Regulatory Factor 5 (IRF5) Gene Variants are Associated with Multiple Sclerosis in Three Distinct Populations

Kristjansdottir, Gudlaug; Sandling, Johanna K; Bonetti, Alessandro; Roos, Izaura M et al.

Ingår i Journal of Medical Genetics, s. 362-369, 2008

• DOI för Interferon Regulatory Factor 5 (IRF5) Gene Variants are Associated with Multiple Sclerosis in Three Distinct Populations

Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

Gustafsdottir, Sigrun M; Wennström, Stefan; Fredriksson, Simon; Schallmeiner, Edith et al.

Ingår i Clinical Chemistry, s. 1218-1225, 2008

• DOI för Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

Biobanking for Europe

Yuille, Martin; van Ommen, Gert-Jan; Bréchot, Christian; Cambon-Thomsen, Anne et al.

Ingår i Briefings in Bioinformatics, s. 14-24, 2008

• DOI för Biobanking for Europe

A dual-tag microarray platform for high-performance nucleic acid and protein analyses

Ericsson, Olle; Jarvius, Jonas; Schallmeiner, Edith; Howell, MAthias et al.

Ingår i Nucleic Acids Research, 2008

• DOI för A dual-tag microarray platform for high-performance nucleic acid and protein analyses

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay.

Söderberg, Ola; Leuchowius, Karl-Johan; Gullberg, Mats; Jarvius, Malin et al.

Ingår i Methods, s. 227-32, 2008

• DOI för Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay.

Novel and highly recurrent chromosomal alterations in Sézary syndrome

Vermeer, Maarten H; van Doorn, Remco; Dijkman, Remco; Mao, Xin et al.

Ingår i Cancer Research, s. 2689-2698, 2008

• DOI för Novel and highly recurrent chromosomal alterations in Sézary syndrome

Evaluation of a novel proximity ligation assay for the sensitive and rapid detection of foot-and-mouth disease virus

Nordengrahn, Ann; Gustafsdottir, Sigrun M.; Ebert, Katja; Reid, Scott M. et al.

Ingår i Veterinary Microbiology, s. 227-236, 2008

• DOI för Evaluation of a novel proximity ligation assay for the sensitive and rapid detection of foot-and-mouth disease virus

Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses by use of padlock probes

Gyarmati, Péter; Conze, Tim; Zohari, Siamak; LeBlanc, Neil et al.

Ingår i Journal of Clinical Microbiology, s. 1747-1751, 2008

• DOI för Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses by use of padlock probes

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

Szado, Tania; Vanderheyden, Veerle; Parys, Jan B; De Smedt, Humbert et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 2427-2432, 2008

• DOI för Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

Ligation-based molecular tools for lab-on-a-chip devices

Melin, Jonas; Jarvius, Jonas; Larsson, Chatarina; Söderberg, Ola et al.

Ingår i New Biotechnology, s. 42-8, 2008

• DOI för Ligation-based molecular tools for lab-on-a-chip devices

In vitro analysis of DNA-protein interactions by proximity ligation

Gustafsdottir, Sigrun M.; Schlingemann, Jörg; Rada-Iglesias, Alvaro; Schallmeiner, Edith et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 3067-3072, 2007

• DOI för In vitro analysis of DNA-protein interactions by proximity ligation

Evaluation of beta globin mRNA as an early marker of haemoglobin response to epoetin treatment

Birgegård, Gunnar; Dahl, Fredrik; Glimelius, Bengt; Landegren, Ulf

Ingår i Medical Oncology, s. 318-322, 2007

• DOI för Evaluation of beta globin mRNA as an early marker of haemoglobin response to epoetin treatment

Self-assembly of proximity probes for flexible and modular proximity ligation assays

Darmanis, Spyros; Kähler, Anna; Spångberg, Lena; Kamali-Moghaddam, Masood et al.

Ingår i BioTechniques, s. 443-450, 2007

• DOI för Self-assembly of proximity probes for flexible and modular proximity ligation assays

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

Taussig, Michael J.; Stoevesandt, Oda; Borrebaeck, Carl A. K.; Bradbury, Andrew R. et al.

Ingår i Nature Methods, s. 13-17, 2007

• DOI för ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Abramsson, Alexandra; Kurup, Sindhulakshmi; Yamada, Shuhei; Lindblom, Per et al.

Ingår i Genes & Development, s. 316-331, 2007

• DOI för Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Sensitive protein detection via triple-binder proximity ligation assays

Schallmeiner, Edith; Oksanen, Elli; Ericsson, Olle; Spångberg, Lena et al.

Ingår i Nature Methods, s. 135-137, 2007

• DOI för Sensitive protein detection via triple-binder proximity ligation assays

In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method

Jarvius, Malin; Paulsson, Janna; Weibrecht, Irene; Leuchowius, Karl-Johan et al.

Ingår i Molecular & Cellular Proteomics, s. 1500-1509, 2007

• DOI för In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method

Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes

Banér, Johan; Gyarmati, Péter; Yacoub, Alia; Hakhverdyan, Mikhayil et al.

Ingår i Journal of Virological Methods, s. 200-206, 2007

• DOI för Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes

Detection of individual microbial pathogens by proximity ligation

Gustafsdottir, Sigrun M.; Nordengrahn, Ann; Fredriksson, Simon; Wallgren, Per et al.

Ingår i Clinical Chemistry, s. 1152-1160, 2006

• DOI för Detection of individual microbial pathogens by proximity ligation

DNA Skyline: fonts to facilitate visual inspection of nucleic acid sequences

Jarvius, Jonas; Landegren, Ulf

Ingår i BioTechniques, s. 740, 2006

• DOI för DNA Skyline: fonts to facilitate visual inspection of nucleic acid sequences

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Söderberg, Ola; Gullberg, Mats; Jarvius, Malin; Ridderstråle, Karin et al.

Ingår i Nature Methods, s. 995-1000, 2006

• DOI för Direct observation of individual endogenous protein complexes in situ by proximity ligation

Molecular markers for discrimination of benign and malignant follicular thyroid tumors

Fryknäs, Mårten; Wickenberg Bolin, Ulrika; Göransson, Hanna; Gustafsson, Mats G et al.

Ingår i Tumor Biology, s. 211-220, 2006

• DOI för Molecular markers for discrimination of benign and malignant follicular thyroid tumors

[Molecular medicine tools. Future prospects with new techniques]

Landegren, Ulf; Kamali-Moghaddam, Masood; Nilsson, Mats

Ingår i Lakartidningen, s. 2947-52, 2006

A sensitive proximity ligation assay for active PSA.

Zhu, undefined; Koistinen, undefined; Wu, undefined; Närvänen, undefined et al.

Ingår i Biol Chem, s. 769-72, 2006

PieceMaker: selection of DNA fragments for selector-guided multiplex amplification

Stenberg, Johan; Dahl, Fredrik; Landegren, Ulf; Nilsson, Mats

Ingår i Nucleic Acids Research, 2005

• DOI för PieceMaker: selection of DNA fragments for selector-guided multiplex amplification
• Ladda ner fulltext (pdf) av PieceMaker: selection of DNA fragments for selector-guided multiplex amplification

ProbeMaker: an extensible framework for design of sets of oligonucleotide probes

Stenberg, Johan; Nilsson, Mats; Landegren, Ulf

Ingår i BMC Bioinformatics, s. 229, 2005

• DOI för ProbeMaker: an extensible framework for design of sets of oligonucleotide probes

Thermoplastic microfluidic platform for single-molecule detection, cell culture and actuation

Melin, Jonas; Johansson, Henrik; Söderberg, Ola; Nikolajeff, Fredrik et al.

Ingår i Analytical Chemistry, s. 7122-30, 2005

• DOI för Thermoplastic microfluidic platform for single-molecule detection, cell culture and actuation

Analysis of T-Cell Receptor V{beta} Gene Repertoires after Immune Stimulation and in Malignancy by Use of Padlock Probes and Microarrays.

Banér, Johan; Marits, Per; Nilsson, Mats; Winqvist, Ola et al.

Ingår i Clin Chem, s. 768-75, 2005

Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study

Wedrén, Sara; Lovmar, Lovisa; Humphreys, Keith; Magnusson, Cecilia et al.

Ingår i Breast Cancer Research, 2004

• DOI för Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study

Molecular tools for a molecular medicine: analyzing genes, transcripts and proteins using padlock and proximity probes

Landegren, Ulf; Schallmeiner, Edith; Nilsson, Mats; Fredriksson, Simon et al.

Ingår i Journal of Molecular Recognition, s. 194-7, 2004

• DOI för Molecular tools for a molecular medicine: analyzing genes, transcripts and proteins using padlock and proximity probes

Cytokine detection by antibody-based proximity ligation

Gullberg, Mats; Gústafsdóttir, Sigrun M.; Schallmeiner, Edith; Jarvius, Jonas et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 8420-4, 2004

• DOI för Cytokine detection by antibody-based proximity ligation

In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes.

Larsson, Chatarina; Koch, undefined; Nygren, undefined; Janssen, undefined et al.

Ingår i Nat Methods, s. 227-232, 2004

Circle-to-circle amplification for precise and sensitive DNA analysis.

Dahl, Fredrik; Banér, Johan; Gullberg, Mats; Mendel-Hartvig, Maritha et al.

Ingår i Proc Natl Acad Sci U S A, s. 4548-53, 2004

Oligonucleotide ligation assay

Jarvius, Jonas; Nilsson, Mats; Landegren, Ulf

Ingår i Methods in Molecular Biology, s. 215-28, 2003

Padlock and proximity probes for in situ and array-based analyses: tools for the post genomic era

Landegren, Ulf; Dahl, Fredrik; Nilsson, Mats; Fredriksson, Simon et al.

Ingår i Comparative and functional genomics, s. 525-30, 2003

• DOI för Padlock and proximity probes for in situ and array-based analyses: tools for the post genomic era

Parallel gene analysis with allele-specific padlock probes and tag microarrays

Banér, Johan; Isaksson, Anders; Waldenström, Erik; Jarvius, Jonas et al.

Ingår i Nucleic Acids Research, 2003

Multiplexed genotyping with sequence-tagged molecular inversion probes

Hardenbol, Paul; Banér, Johan; Jain, Maneesh; Nilsson, Mats et al.

Ingår i Nature Biotechnology, s. 673-8, 2003

• DOI för Multiplexed genotyping with sequence-tagged molecular inversion probes

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.

Lindblom, Per; Gerhardt, Holger; Liebner, Stefan; Abramsson, Alexandra et al.

Ingår i Genes Dev, s. 1835-40, 2003

Protein detection using proximity-dependent DNA ligation assays

Fredriksson, Simon; Gullberg, Mats; Jarvius, Jonas; Olsson, Charlotta et al.

Ingår i Nature Biotechnology, s. 473-477, 2002

• DOI för Protein detection using proximity-dependent DNA ligation assays

A distinct Th1 immune response precedes the described Th2 response in Islet xenograft rejection

Krook, Henrik; Hagberg, Anette; Song, Zhenshung; Landegren, Ulf et al.

Ingår i Diabetes, s. 79-86, 2002

• DOI för A distinct Th1 immune response precedes the described Th2 response in Islet xenograft rejection

PCR-generated padlock probes detect single nucleotide variation in genomic DNA

Antson, D.O.; Isaksson, A.; Landegren, Ulf; Nilsson, Mats

Ingår i Nucleic Acids Research, 2000

X-linked recessive panhypopituitarism associated with a regional duplication in Xq25-q26

Lagerström-Fermér, Maria; Sundvall, Mats; Johnsen, Elsy; Warne, GL et al.

Ingår i American Journal of Human Genetics, s. 910-916, 1997

Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta

Lagerström-Fermér, Maria; Nilsson, Mats; Backman, B; Salido, E et al.

Ingår i Genomics, s. 159-162, 1995

• DOI för Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta

An international perspective on the future of systemic sclerosis research

Abraham, David J.; Black, Carol M.; Denton, Christopher P.; Distler, Jörg H. W. et al.

Ingår i Nature Reviews Rheumatology, s. 174-187, 2025

• DOI för An international perspective on the future of systemic sclerosis research

Molecular tools to monitor health and disease - and lucky coincidences

Landegren, Ulf

Ingår i Upsala Journal of Medical Sciences, 2022

• DOI för Molecular tools to monitor health and disease - and lucky coincidences
• Ladda ner fulltext (pdf) av Molecular tools to monitor health and disease - and lucky coincidences

Cancer diagnostics based on plasma protein biomarkers: hard times but great expectations

Landegren, Ulf; Hammond, Maria

Ingår i Molecular Oncology, s. 1715-1726, 2021

• DOI för Cancer diagnostics based on plasma protein biomarkers: hard times but great expectations
• Ladda ner fulltext (pdf) av Cancer diagnostics based on plasma protein biomarkers: hard times but great expectations

A myopic perspective on the future of protein diagnostics

Landegren, Ulf; Al-Amin, Rasel A.; Björkesten, Johan

Ingår i New Biotechnology, s. 14-18, 2018

• DOI för A myopic perspective on the future of protein diagnostics
• Ladda ner fulltext (pdf) av A myopic perspective on the future of protein diagnostics

Detection of Extracellular Vesicles Using Proximity Ligation Assay with Flow Cytometry Readout – ExoPLA: In Print

Löf, Liza; Arngården, Linda; Ebai, Tonge; Landegren, Ulf et al.

Ingår i Current Protocol in Cytometry, 2017

• DOI för Detection of Extracellular Vesicles Using Proximity Ligation Assay with Flow Cytometry Readout – ExoPLA: In Print

Close Encounters: Probing Proximal Proteins in Live or Fixed Cells

Lönn, Peter; Landegren, Ulf

Ingår i TIBS -Trends in Biochemical Sciences. Regular ed., s. 504-515, 2017

• DOI för Close Encounters: Probing Proximal Proteins in Live or Fixed Cells

Protein biomarker validation via proximity ligation assays

Blokzijl, Andries; Nong, Rachel; Darmanis, S.; Hertz, E. et al.

Ingår i Biochimica et Biophysica Acta - Proteins and Proteomics, s. 933-939, 2014

• DOI för Protein biomarker validation via proximity ligation assays

DNA-assisted protein detection technologies

Nong, Rachel Yuan; Gu, Jijuan; Darmanis, Spyros; Kamali-Moghaddam, Masood et al.

Ingår i Expert Review of Proteomics, s. 21-32, 2012

• DOI för DNA-assisted protein detection technologies

Molecular tools for companion diagnostics

Zieba, Agata; Grannas, Karin; Söderberg, Ola; Gullberg, Mats et al.

Ingår i New Biotechnology, s. 634-640, 2012

• DOI för Molecular tools for companion diagnostics

Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

Blokzijl, Andries; Friedman, Mikaela; Pontén, Fredrik; Landegren, Ulf

Ingår i Journal of Internal Medicine, s. 232-245, 2010

• DOI för Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

Analysis of Genes, Transcripts, and Proteins via DNA Ligation

Conze, Tim; Shetye, Alysha; Tanaka, Yuki; Gu, Jijuan et al.

Ingår i Annual review of analytical chemistry, s. 215-239, 2009

• DOI för Analysis of Genes, Transcripts, and Proteins via DNA Ligation

Gnothi seauton - känn dig själv! Vill du kartlägga din arvsmassa? [Gnothi seauton--know thyself! Do you want to survey your genome?]

Gustavson, Kari-Henrik; Landegren, Ulf

Ingår i Läkartidningen, s. 345-6, 2008

Proximity ligation assays for sensitive and specific protein analyses.

Gustafsdottir, Sigrun M; Schallmeiner, Edith; Fredriksson, Simon; Gullberg, Mats et al.

Ingår i Anal Biochem, s. 2-9, 2005

Protein Diagnostics by Proximity Ligation: Combining Multiple Recognition and DNA Amplification for Improved Protein Analyses

Cane, Gaëlle; Leuchowius, Karl-Johan; Söderberg, Ola; Kamali-Moghaddam, Masood et al.

Ingår i Molecular Diagnostics (Third Edition), s. 219-231, Academia Press, 2017

Protein diagnostics by proximity ligation: Combining multiple recognition and DNA amplification for improved protein analysis

Leuchowius, Karl-Johan; Söderberg, Ola; Kamali-Moghaddam, Masood; Jarvius, Malin et al.

Ingår i Molecular Diagnostics, s. 299-306, Elsevier/Academic Press, 2010

Proximity ligation: a specific and versatile tool for the proteomic era.

Söderberg, Ola; Leuchowius, Karl-Johan; Kamali-Moghaddam, Masood; Jarvius, Malin et al.

Ingår i Genet Eng (N Y)., s. 190, Springer, 2007

Emerging tools for dissecting complex disease

Landegren, Ulf

Ingår i The hereditary basis of rheumatic diseases, s. 107-117, Birkhäuser Verlag, 2006

Detection techniques for single nucleotide polymorphisms.

Howell, WM; Stenberg, Johan; Nilsson, Mats; Landegren, Ulf

Ingår i Nucleic acid testing in human disease, s. 139-169, CRC, 2006

Ligase-mediated molecular analyses

Stenberg, Johan; Nilsson, Mats; Landegren, Ulf

Ingår i Encyclopedia of molecular biology, s. 179-193, VCH Publishers, 2004

Amplified Single Molecule Detection in a Thermoplastic Microfluidic System

Jarvius, Jonas; Melin, Jonas; Göransson, Jenny; Göransson, Henrik et al.

Ingår i Poster at microTAS-2005 October 9-13, Boston, USA, 2005

A Novel Microfluidic Platform Design Combining Actuators, Cell Culturing and Sensitive Fluorescence Detection with Cheap Disposable Microchips

Melin, Jonas; Johansson, H.; Söderberg, Ola; Nikolajeff, Fredrik et al.

Ingår i Oral at microTAS-2004 conference, Lund, Sweden, 2004

Sensitive Measurement of Cellular Drug-Target Engagement Using Multiplex Proximity Extension Assays

Al-Amin, Abdullah; Gallant, Caroline; Lööf, Sara; Lengqvist, Johan et al.

High-throughput in situ mapping of phosphorylated protein complexes across the cell cycle and in response to drugs

Lönn, Peter; Al-Amin, Rasel A.; Heldin, Johan; Gallini, Radiosa et al.

Multiplex digital enumeration of circular DNA molecules on solid supports

Björkesten, Johan; Patil, Sourabh; Fredolini, Claudia; Lönn, Peter et al.

Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in blood and saliva samples using antibody proximity extension assays (AbPEA)

Wang, Mengqi; Kamali-Moghaddam, Masood; Löf, Liza; Cortabarría Fernandez, Matilde et al.

Surface protein profiles of extracellular vesicles reveal SARS-CoV-2 infection

Wang, Mengqi; Lu, Xi; Sinha, Tanay Kumar; Nilsson, Kenneth et al.

Highly selective in situ detection of mutant transcripts with gap-fill padlock probes and superRCA

Wang, Mengqi; Chen, Lei; Micke, Patrick; Strell, Carina et al.

Target Engagement-Mediated Amplification for Monitoring Drug-Target Interactions in Situ

Al-Amin, Rasel A.; Johansson, Lars; Landegren, Nils; Löf, Liza et al.

The hunt for cancer biomarkers: Proximity ligation – a new technology for ultra-sensitive protein analysis

Alderborn, Anders; Kamali, Masood; Söderberg, Ola; Schlingemann, Heidi et al.

2006