Bengt Westermark

p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica et al.

Ingår i International Journal of Molecular Sciences, 2025

• DOI för p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics
• Ladda ner fulltext (pdf) av p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Special issue: frontiers in recent advances on cancer diagnosis and treatment

Westermark, Bengt; Heldin, Carl-Henrik

Ingår i Upsala Journal of Medical Sciences, 2024

• DOI för Special issue: frontiers in recent advances on cancer diagnosis and treatment
• Ladda ner fulltext (pdf) av Special issue: frontiers in recent advances on cancer diagnosis and treatment

Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Ingår i Scientific Reports, 2024

• DOI för Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
• Ladda ner fulltext (pdf) av Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Ingår i Cancer Cell, s. 1134-1151, 2023

• DOI för Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
• Ladda ner fulltext (pdf) av Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Ingår i ACS Applied Bio Materials, s. 3790-3797, 2023

• DOI för Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
• Ladda ner fulltext (pdf) av Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica et al.

Ingår i International Journal of Molecular Sciences, 2025

• DOI för p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics
• Ladda ner fulltext (pdf) av p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Special issue: frontiers in recent advances on cancer diagnosis and treatment

Westermark, Bengt; Heldin, Carl-Henrik

Ingår i Upsala Journal of Medical Sciences, 2024

• DOI för Special issue: frontiers in recent advances on cancer diagnosis and treatment
• Ladda ner fulltext (pdf) av Special issue: frontiers in recent advances on cancer diagnosis and treatment

Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Ingår i Scientific Reports, 2024

• DOI för Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
• Ladda ner fulltext (pdf) av Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Ingår i Cancer Cell, s. 1134-1151, 2023

• DOI för Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
• Ladda ner fulltext (pdf) av Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Ilkhanizadeh, Shirin; Gracias, Aileen; Aslund, Andreas K. O.; Back, Marcus et al.

Ingår i ACS Applied Bio Materials, s. 3790-3797, 2023

• DOI för Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative
• Ladda ner fulltext (pdf) av Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative

Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Ingår i Molecular Systems Biology, 2021

• DOI för Modeling glioblastoma heterogeneity as a dynamic network of cell states
• Ladda ner fulltext (pdf) av Modeling glioblastoma heterogeneity as a dynamic network of cell states

A human cell type similar to murine central nervous system perivascular fibroblasts

Liu, Jianping; He, Liqun; Muhl, Lars; Mocci, Giuseppe et al.

Ingår i Experimental Cell Research, 2021

• DOI för A human cell type similar to murine central nervous system perivascular fibroblasts
• Ladda ner fulltext (pdf) av A human cell type similar to murine central nervous system perivascular fibroblasts

Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Lundin, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Ingår i Molecular Systems Biology, 2021

• DOI för Modeling glioblastoma heterogeneity as a dynamic network of cell states
• Ladda ner fulltext (pdf) av Modeling glioblastoma heterogeneity as a dynamic network of cell states

Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida et al.

Ingår i Molecular Cancer Research, s. 981-991, 2020

• DOI för Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Cancer, Matko; Drews, Lisa F.; Bengtsson, Johan; Bolin, Sara et al.

Ingår i Cell Death and Disease, 2019

• DOI för BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
• Ladda ner fulltext (pdf) av BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Kaffes, Ioannis; Szulzewsky, Frank; Chen, Zhihong; Herting, Cameron J. et al.

Ingår i Oncoimmunology, 2019

• DOI för Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
• Ladda ner fulltext (pdf) av Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

Niklasson, Mia; Bergström, Tobias; Jarvius, Malin; Sundström, Anders et al.

Ingår i Journal of Pathology, s. 295-307, 2019

• DOI för Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Ingår i Acta Oncologica, s. 187-194, 2018

• DOI för U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
• Ladda ner fulltext (pdf) av U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Attarha, Sanaz; Roy, Ananya; Westermark, Bengt; Tchougounova, Elena

Ingår i Cellular Signalling, s. 81-92, 2017

• DOI för Mast cells modulate proliferation, migration and sternness of glioma cells through downregulation of GSK3 beta expression and inhibition of STAT3 activation

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Ingår i Cell Reports, s. 380-389, 2016

• DOI för Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
• Ladda ner fulltext (pdf) av Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Segerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergström, Tobias et al.

Ingår i Cell Reports, s. 2994-3009, 2016

• DOI för Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
• Ladda ner fulltext (pdf) av Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Ingår i Oncotarget, s. 73200-73215, 2016

• DOI för Case-specific potentiation of glioblastoma drugs by pterostilbene

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Wee, Boyoung; Pietras, Alexander; Ozawa, Tatsuya; Bazzoli, Elena et al.

Ingår i Scientific Reports, 2016

• DOI för ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells
• Ladda ner fulltext (pdf) av ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Origin of the U87MG glioma cell line: Good news and bad news

Allen, Marie; Bjerke, Mia; Edlund, Hanna; Nelander, Sven et al.

Ingår i Science Translational Medicine, 2016

• DOI för Origin of the U87MG glioma cell line: Good news and bad news

Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs

Agarwal, Prasoon; Enroth, Stefan; Teichmann, Martin; Jernberg Wiklund, Helena et al.

Ingår i Cell Cycle, s. 1558-1571, 2016

• DOI för Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs
• Ladda ner fulltext (pdf) av Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs

CGGBP1 mitigates cytosine methylation at repetitive DNA sequences

Agarwal, Prasoon; Collier, Paul; Fritz, Markus Hsi-Yang; Benes, Vladimir et al.

Ingår i BMC Genomics, 2015

• DOI för CGGBP1 mitigates cytosine methylation at repetitive DNA sequences
• Ladda ner fulltext (pdf) av CGGBP1 mitigates cytosine methylation at repetitive DNA sequences

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Ingår i Oncotarget, s. 23647-23661, 2015

• DOI för Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
• Ladda ner fulltext (pdf) av Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Yuan; Bergström, Tobias; Jiang, Yiwen; Johansson, Patrik et al.

Ingår i EBioMedicine, s. 1351-1363, 2015

• DOI för The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
• Ladda ner fulltext (pdf) av The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from Human glioblastoma

Babateen, Omar; Jin, Zhe; Bhandage, Amol K.; Korol, Sergiy V et al.

Ingår i European Journal of Pharmacology, s. 101-107, 2015

• DOI för Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from Human glioblastoma

GABA-A receptor currents in a cell line (U3047MG) derived from a human glioblastoma tumor are enhanced by etomidate, propofol and diazepam

Babateen, Omar M.; Jin, Zhe; Bhandage, Amol K.; Korol, Sergiy V. et al.

Ingår i Acta Physiologica, s. 100-100, 2014

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

Torsvik, Anja; Stieber, Daniel; Enger, Per Oyvind; Golebiewska, Anna et al.

Ingår i Cancer Medicine, s. 812-824, 2014

• DOI för U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells
• Ladda ner fulltext (pdf) av U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Põlajeva, Jelena; Bergström, Tobias; Edqvist, Per-Henrik; Lundequist, Anders et al.

Ingår i Molecular Oncology, s. 50-58, 2014

• DOI för Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Wee, Shimei; Niklasson, Maria; Marinescu, Voichita Dana; Segerman, Anna et al.

Ingår i PLOS ONE, 2014

• DOI för Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
• Ladda ner fulltext (pdf) av Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Kitambi, Satish Srinivas; Toledo, Enrique M.; Usoskin, Dmitry; Wee, Shimei et al.

Ingår i Cell, s. 313-328, 2014

• DOI för Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Taming the cancer cell: Introduction

Jernberg Wiklund, Helena; Westermark, Bengt

Ingår i Journal of Internal Medicine, s. 2-4, 2014

• DOI för Taming the cancer cell: Introduction

CGGBP1 phosphorylation constitutes a telomere-protection signal

Singh, Umashankar; Maturi, Varun; Jones, Rhiannon E; Paulsson, Ylva et al.

Ingår i Cell Cycle, s. 96-105, 2014

• DOI för CGGBP1 phosphorylation constitutes a telomere-protection signal

Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Ingår i PLOS ONE, 2013

• DOI för Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
• Ladda ner fulltext (pdf) av Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Schmidt, Linnea; Kling, Teresia; Monsefi, Naser; Olsson, Maja et al.

Ingår i Neuro-Oncology, s. 1469-1478, 2013

• DOI för Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions

Sox21 inhibits glioma progression in vivo by reducing Sox2 and stimulating aberrant differentiation

Caglayan, Demet; Lundin, Erika; Kastemar, Marianne; Westermark, Bengt et al.

Ingår i International Journal of Cancer, s. 1345-1356, 2013

• DOI för Sox21 inhibits glioma progression in vivo by reducing Sox2 and stimulating aberrant differentiation

Evidence for multiple forms and modifications of human POT1

Singh, Umashankar; Maturi, Varun; Westermark, Bengt

Ingår i DNA Repair, s. 876-877, 2013

• DOI för Evidence for multiple forms and modifications of human POT1

Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation

Caglayan, Demet; Lundin, Erika; Kastemar, Marianne; Westermark, Bengt et al.

Ingår i International Journal of Cancer, s. 1345-1356, 2013

• DOI för Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation

miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma

Põlajeva, Jelena; Swartling, Fredrik; Jiang, Yiwen; Singh, Umashankar et al.

Ingår i BMC Cancer, s. 378, 2012

• DOI för miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma
• Ladda ner fulltext (pdf) av miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma

Induced Expression of Sox21 Inhibits Glioma Progression in Vivo by Stimulating Aberrant Differentiation

Ferletta, Maria; Caglayan, Demet; Lundin, Erika; Kastemar, Marianne et al.

Ingår i European Journal of Cancer, 2012

• DOI för Induced Expression of Sox21 Inhibits Glioma Progression in Vivo by Stimulating Aberrant Differentiation

CGGBP1 regulates cell cycle in cancer cells

Singh, Umashankar; Roswall, Pernilla; Uhrbom, Lene; Westermark, Bengt

Ingår i BMC Molecular Biology, s. 28, 2011

• DOI för CGGBP1 regulates cell cycle in cancer cells
• Ladda ner fulltext (pdf) av CGGBP1 regulates cell cycle in cancer cells

PDGF-B Can sustain self-renewal and tumorigenicity of experimental glioma-derived cancer-initiating cells by preventing oligodendrocyte differentiation

Jiang, Yiwen; Boije, Maria; Westermark, Bengt; Uhrbom, Lene

Ingår i Neoplasia, s. 492-503, 2011

• DOI för PDGF-B Can sustain self-renewal and tumorigenicity of experimental glioma-derived cancer-initiating cells by preventing oligodendrocyte differentiation

Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells

Ferletta, Maria; Caglayan, Demet; Mokvist, Liza; Yiwen, Jiang et al.

Ingår i International Journal of Cancer, s. 45-60, 2011

• DOI för Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells

Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12

Põlajeva, Jelena; Sjösten, Anna M; Lager, Nina; Kastemar, Marianne et al.

Ingår i PLOS ONE, 2011

• DOI för Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12
• Ladda ner fulltext (pdf) av Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12

CGGBP1 is a nuclear and midbody protein regulating abscission

Singh, Umashankar; Westermark, Bengt

Ingår i Experimental Cell Research, s. 143-150, 2011

• DOI för CGGBP1 is a nuclear and midbody protein regulating abscission

Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis

Nyström, Anna-Maja; Ekvall, Sara; Thuresson, Ann-Charlotte; Kamali-Moghaddam, Masood et al.

Ingår i European Journal of Medical Genetics, s. 117-121, 2010

• DOI för Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis

Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines

Swartling, Fredrik J.; Ferletta, Maria; Kastemar, Marianne; Weiss, W. A. et al.

Ingår i Oncogene, s. 3121-3131, 2009

• DOI för Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines

A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions

Singh, Umashankar; Bongcam-Rudloff, Erik; Westermark, Bengt

Ingår i PLoS ONE, 2009

• DOI för A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions

Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence

Tchougounova, Elena; Jiang, Yiwen; Bråsäter, Daniel; Lindberg, Nanna et al.

Ingår i Oncogene, s. 1537-1548, 2009

• DOI för Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence

Herbal melanin activates TLR4/NF-kappaB signaling pathway

Öberg, Fredrik; Haseeb, Adil; Ahnfelt, Matilda; Pontén, Fredrik et al.

Ingår i Phytomedicine, s. 477-84, 2009

• DOI för Herbal melanin activates TLR4/NF-kappaB signaling pathway

GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background

Hede, Sanna-Maria; Hansson, Inga; Afink, Gijs B; Eriksson, Anna et al.

Ingår i Glia, s. 1143-1153, 2009

• DOI för GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background

Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis

Ferletta, Maria; Uhrbom, Lene; Olofsson, Tommie; Pontén, Fredrik et al.

Ingår i Molecular Cancer Research, s. 891-897, 2007

• DOI för Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis

Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma

Tchougounova, Elena; Kastemar, Marianne; Bråsäter, Daniel; Holland, E C et al.

Ingår i Oncogene, s. 6289-6296, 2007

• DOI för Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma

Autocrine/Paracrine platelet-derived growth factor regulates proliferation of neural progenitor cells

Erlandsson, Anna; Brännvall, Karin; Gustafsdottir, Sigrun; Westermark, Bengt et al.

Ingår i Cancer Research, s. 8042-8048, 2006

• DOI för Autocrine/Paracrine platelet-derived growth factor regulates proliferation of neural progenitor cells

Effect of herbal melanin on IL-8: a possible role of Toll-like receptor 4 (TLR4).

El-Obeid, Adila; Hassib, Adil; Pontén, Fredrik; Westermark, Bengt

Ingår i Biochem Biophys Res Commun, s. 1200-6, 2006

Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice

Johansson, Fredrik K; Göransson, Hanna; Westermark, Bengt

Ingår i Oncogene, s. 3896-3905, 2005

• DOI för Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice

Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.

Uhrbom, Lene; Kastemar, Marianne; Johansson, Fredrik K; Westermark, Bengt et al.

Ingår i Cancer Res, s. 2065-9, 2005

Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging

Johansson, Fredrik K.; Brodd, Josefin; Eklöf, Charlotta; Ferletta, Maria et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 11334-11337, 2004

• DOI för Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging

Soluble factors released by virus specific activated cytotoxicT-lymphocytes induce apoptotic death of astroglioma cell lines

Sabri, Farideh; Chiodi, Francesca; Piret, Jean-Pascal; Wei, Cheng-Hong et al.

Ingår i Brain Pathology, s. 165-175, 2003

• DOI för Soluble factors released by virus specific activated cytotoxicT-lymphocytes induce apoptotic death of astroglioma cell lines

p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.

Wolf, Rebecca M.; Draghi, Nicole; Liang, Xiquan; Dai, Chengkai et al.

Ingår i Development, Genes and Evolution, s. 476-487, 2003

• DOI för p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.

Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts

Forsberg-Nilsson, Karin; Erlandsson, Anna; Zhang, Xiao-Qun; Ueda, Hideho et al.

Ingår i Glia, s. 276-89, 2003

• DOI för Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts

Complementary effects of platelet-derived growth factor autocrine stimulation and p53 or Ink4a-Arf deletion in a mouse glioma model.

Hesselager, Göran; Uhrbom, Lene; Westermark, Bengt; Nister, Monica

Ingår i Cancer Research, s. 4305, 2003

TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor

El-Obeid, A.; Hesselager, Göran; Westermark, Bengt; Nister, M.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 349-58, 2002

• DOI för TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor

A 1.8kb GFAP-promoter fragment is active in specific regions of theembryonic CNS

Andrae, Johanna; Bongcam-Rudloff, Erik; Hansson, Inga; Lendahl, Urban et al.

Ingår i Mechanisms of Development, s. 181-5, 2001

• DOI för A 1.8kb GFAP-promoter fragment is active in specific regions of theembryonic CNS

Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin

Hellmen, Eva; Moller, Maria; Blankenstein, Marinus A.; Andersson, Leif et al.

Ingår i Breast Cancer Research and Treatment, s. 197-210, 2000

• DOI för Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin

Epidermal growth factor receptor signaling activates Met in human anaplastic thyroid carcinoma cells

Bergström, J.Daniel; Westermark, Bengt; Heldin, Nils-Erik

Ingår i Experimental Cell Research, s. 293-299, 2000

• DOI för Epidermal growth factor receptor signaling activates Met in human anaplastic thyroid carcinoma cells

PDGF B mRNA variants in human tumors with similarity to the v-sis oncogene: Expression of cellular PDGF B protein is associated with exon 1 divergence, but not with a 3'UTR splice variant

Heller, Susanne; Scheibenpflug, Lena; Westermark, Bengt; Nistér, Monica

Ingår i Int J Cancer, s. 211-222, 2000

Dependence of autocrine growth factor stimulation in platelet-derived growth factor-B-induced mouse brain tumor cells

Uhrbom, Lene; Hesselager, Göran; Östman, Arne; Nistér, Monica et al.

Ingår i Int J Cancer, s. 398-406, 2000

Modulation of phenotype and induction of irregular vessels accompany high tumorigenic potential of clonal human glioma cells xenografted to nude-rat brain

Enblad, Per; Hesselager, Göran; Bongcam-Rudloff, Erik; Hallin, Inga et al.

Ingår i Int J Cancer, s. 819-828, 2000

Expression of transforming growth factor-beta1, activin A, and their receptors in thyroid follicle cells: negative regulation of thyrocyte growth and function.

Franzén, Åsa; Piek, Ester; Westermark, Bengt; ten Dijke, Peter et al.

Ingår i Endocrinology, s. 4300, 1999

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

Zhang, Xiao-Qun; Afink, Gijs; Svensson, Kristian; Jacobs, Jacqueline J.L. et al.

Ingår i Mechanisms of Development, s. 167-180, 1998

• DOI för Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

Afrakhte, Mozhgan; Morén, Anita; Jossan, Surinder; Itoh, Susumu et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 505-11, 1998

• DOI för Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

Induction of brain tumors in mice using a recombinant PDGF B retrovirus

Uhrbom, Lene; Hesselager, Göran; Nister, Monica; Westermark, Bengt

Ingår i Cancer Research, s. 5275-5279, 1998

Induction of senescence in human malignant glioma cells by p16INK4A

Uhrbom, Lene; Nister, Monica; Westermark, Bengt

Ingår i Oncogene, s. 111, 1997

Production of cell-associated PDGF-AA by a human sarcoma cell line: Evidence for a latent autocrine effect

Afrakhte, M; Nistér, M; Östman, A; Westermark, B et al.

Ingår i Int J Cancer, s. 802-809, 1996

Luteal failure in transgenic mice carrying a PDGF dominant-negative mutant/GH hybrid transgene

Pekny, Milos; Pekna, M; Östman, A; Törnell, J et al.

Ingår i Transgenics (Basel. Print), s. 515-523, 1995

Detection of TP53 gene mutation in human meningiomas: A study using immunohistochemistry, polymerase chain reaction/single-strand conformation polymorphism and DNA sequencing techniques on paraffin-embedded samples

Wang, J-L; Zhang, Z-J; Hartman, M; Smits, A et al.

Ingår i Int J Cancer, s. 223-228, 1995

Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Heldin, Carl-Henrik; Östman, Arne; Eriksson, Anders; Siegbahn, Agneta et al.

Ingår i Kidney International, s. 571-574, 1992

• DOI för Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Expression of platelet-derived growth factor and its receptors in proliferative disorders of fibroblastic origin

Smits, Anja; Funa, K; Vassbotn, F S; Beausang-Linder, M et al.

Ingår i American Journal of Pathology, s. 639-648, 1992

Differential effects of platelet-derived growth factors on fetal hippocampal and cortical grafts: evidence from intraocular transplantation in rats

Giacobini, MaiBritt M J; Smits, Anja; Funa, K; Westermark, B et al.

Ingår i Neuroscience Letters, s. 227-231, 1992

• DOI för Differential effects of platelet-derived growth factors on fetal hippocampal and cortical grafts: evidence from intraocular transplantation in rats

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

Blume-Jensen, Peter; Claesson-Welsh, Lena; Siegbahn, Agneta; Zsebo, Krisztina M. et al.

Ingår i EMBO Journal, s. 4121-4128, 1991

Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF

Smits, Anja; Kato, M; Westermark, Bengt; Nistér, M et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 8159-8163, 1991

Rat brain capillary endothelial cells express functional PDGF B-type receptors

Smits, Anja; Hermansson, M; Nistér, M; Karnushina, I et al.

Ingår i Growth Factors, s. 1-8, 1989

A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets.

Nistér, M; Hammacher, A; Mellström, K; Siegbahn, A et al.

Ingår i Cell, s. 791-9, 1988

Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis

Heldin, Carl-Henrik; Lennartsson, Johan; Westermark, Bengt

Ingår i Journal of Internal Medicine, s. 16-44, 2018

• DOI för Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis

CGGBP1-an indispensable protein with ubiquitous cytoprotective functions

Singh, Umashankar; Westermark, Bengt

Ingår i Upsala Journal of Medical Sciences, s. 219-232, 2015

• DOI för CGGBP1-an indispensable protein with ubiquitous cytoprotective functions

Platelet-derived growth factor in glioblastoma-driver or biomarker?

Westermark, Bengt

Ingår i Upsala Journal of Medical Sciences, s. 298-305, 2014

• DOI för Platelet-derived growth factor in glioblastoma-driver or biomarker?

Glioblastoma: a moving target

Westermark, Bengt

Ingår i Upsala Journal of Medical Sciences, s. 251-256, 2012

• DOI för Glioblastoma: a moving target

Glial tumors of the CNS

Nistér, Monica; Uhrbom, Lene; Hesselager, Göran; Westermark, Bengt

Ingår i Glial Cell Development, s. 437, Oxford University Press, 2001

BMP4 induction of a senescence-like phenotype in human glioblastoma cells is dependent on p21

Niklasson, Mia; Dalmo, Erika; Westermark, Bengt

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.

BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Verónica et al.

• DOI för BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence

RAP1GAP Suppression Promotes Stemness and Inhibits Glioblastoma Cell Migration

Põlajeva, Jelena; Kastemar, Marianne; Tchougounova, Elena; Zeller, Kathrin et al.