Gudmar Lönnerholm

An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia

Krali, Olga; Enblad, Anna Pia; Sulyaeva, Julia; Gogishvili, Dea et al.

Ingår i Communications Medicine, 2026

DOI för An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia
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Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Ingår i HemaSphere, 2025

Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling

Orgueira, Adrian Mosquera; Krali, Olga; Miguez, Carlos Perez; Raindo, Andres Peleteiro et al.

Ingår i Clinical Epigenetics, 2024

Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Krali, Olga; Marincevic-Zuniga, Yanara; Arvidsson, Gustav; Enblad, Anna Pia et al.

Ingår i npj Precision Oncology, 2023

Increased MYB alternative promoter usage is associated with relapse in acute lymphoblastic leukemia

Fehr, André; Arvidsson, Gustav; Nordlund, Jessica; Lönnerholm, Gudmar et al.

Ingår i Genes, Chromosomes and Cancer, s. 597-606, 2023

RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children

Chen, Dongfeng; Camponeschi, Alessandro; Nordlund, Jessica; Marincevic-Zuniga, Yanara et al.

Ingår i Cancer Medicine, s. 3997-4003, 2021

Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia

Sayyab, Shumaila; Lundmark, Anders; Larsson, Malin; Ringner, Markus et al.

Ingår i Scientific Reports, 2021

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, Marti; Clot, Guillem; Nadeu, Ferran; Beekman, Renee et al.

Ingår i Nature Cancer, s. 1066-1081, 2020

DOI för The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia by linked-read whole-genome sequencing

Nordlund, Jessica; Marincevic-Zuniga, Yanara; Cavelier, Lucia; Raine, Amanda et al.

Ingår i Scientific Reports, 2020

Overexpression of chromatin remodeling and tyrosine kinase genes in iAMP21-positive acute lymphoblastic leukemia

Ivanov Öfverholm, I.; Zachariadis, V.; Taylan, F.; Marincevic-Zuniga, Yanara et al.

Ingår i Leukemia and Lymphoma, s. 604-613, 2020

CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia

Chen, Dongfeng; Camponeschi, Alessandro; Wu, Qingqing; Gerasimcik, Natalija et al.

Ingår i British Journal of Haematology, s. 418-423, 2019

DOI för CD99 expression is strongly associated with clinical outcome in children with B-cell precursor acute lymphoblastic leukaemia

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Borssen, Magnus; Nordlund, Jessica; Haider, Zahra; Landfors, Mattias et al.

Ingår i Clinical Epigenetics, 2018

CD27 expression and its association with clinical outcome in children and adults with pro-B acute lymphoblastic leukemia

Chen, D.; Gerasimcik, N.; Camponeschi, A.; Tan, Y. et al.

Ingår i Blood Cancer Journal, 2017

Transcriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles

Marincevic-Zuniga, Yanara; Dahlberg, Johan; Nilsson, Sara; Raine, Amanda et al.

Ingår i Journal of Hematology & Oncology, 2017

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands

Wahlberg, Per; Lundmark, Anders; Nordlund, Jessica; Busche, Stephan et al.

Ingår i Epigenomics, s. 1367-1387, 2016

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Lindqvist, C. Mårten; Lundmark, Anders; Nordlund, Jessica; Freyhult, Eva et al.

Ingår i Oncotarget, s. 64071-64088, 2016

DOI för Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia

Marincevic-Zuniga, Yanara; Zachariadis, Vasilios; Cavelier, Lucia; Castor, Anders et al.

Ingår i Haematologica, 2016

DOI för PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array

Marzouka, Nour-al-dain; Nordlund, Jessica; Bäcklin, Christofer L.; Lönnerholm, Gudmar et al.

Ingår i Bioinformatics, s. 1080-1082, 2016

The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

Lindqvist, C Mårten; Nordlund, Jessica; Ekman, Diana; Johansson, Anna et al.

Ingår i Human Mutation, s. 118-128, 2015

DOI för The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing

DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer; Zachariadis, Vasilios; Cavelier, Lucia et al.

Ingår i Clinical Epigenetics, 2015

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Nordlund, Jessica; Bäcklin, Christofer L; Wahlberg, Per; Busche, Stephan et al.

Ingår i Genome Biology, 2013

DOI för Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

Berglund, Eva C; Lindqvist, Carl Mårten; Hayat, Shahina; Overnäs, Elin et al.

Ingår i BMC Genomics, s. 856, 2013

DOI för Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

DNA Methylation Analysis of Bone Marrow Cells at Diagnosis of Acute Lymphoblastic Leukemia and at Remission

Nordlund, Jessica; Milani, Lili; Lundmark, Anders; Lönnerholm, Gudmar et al.

Ingår i PLOS ONE, 2012

The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Nordlund, Jessica; Backlin, Carin; Wahlberg, Per; Forestier, E. et al.

Ingår i European Journal of Cancer, 2012

DOI för The DNA Methylation Landscape of Paediatric Acute Lymphoblastic Leukemia

Digital gene expression profiling of primary acute lymphoblastic leukemia cells

Nordlund, Jessica; Kiialainen, Anna; Karlberg, Olof; Berglund, Eva C et al.

Ingår i Leukemia, s. 1218-1227, 2012

DOI för Digital gene expression profiling of primary acute lymphoblastic leukemia cells

Response: High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia

Staffas, Anna; Kanduri, Meena; Hovland, Randi; Rosenquist, Richard et al.

Ingår i Blood, s. 1087-1088, 2012

DOI för Response: High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia

In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia

Lönnerholm, Gudmar; Thörn, Ingrid; Sundström, Christer; Frost, Britt-Marie et al.

Ingår i Leukemia Research, s. 472-478, 2011

DOI för In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia

Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

Thörn, Ingrid; Forestier, Erik; Botling, Johan; Thuresson, Britt et al.

Ingår i British Journal of Haematology, s. 743-753, 2011

DOI för Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial

Zachariadis, V.; Gauffin, F.; Kuchinskaya, E.; Heyman, M. et al.

Ingår i Leukemia, s. 622-628, 2011

DOI för The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial

Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

Staffas, Anna; Kanduri, Meena; Hovland, Randi; Rosenquist, Richard et al.

Ingår i Blood, s. 5905-5913, 2011

DOI för Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Milani, Lili; Lundmark, Anders; Kiialainen, Anna; Nordlund, Jessica et al.

Ingår i Blood, s. 1214-1225, 2010

DOI för DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia

Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia

Thörn, Ingrid; Botling, Johan; Hermansson, Monica; Lönnerholm, Gudmar et al.

Ingår i Leukemia Research, s. 1047-1054, 2009

DOI för Monitoring minimal residual disease with flow cytometry, antigen-receptor gene rearrangements and fusion transcript quantification in Philadelphia-positive childhood acute lymphoblastic leukemia

In vitro cellular drug sensitivity at diagnosis is correlated to minimal residual disease at end of induction therapy in childhood acute lymphoblastic leukemia

Lönnerholm, Gudmar; Thörn, Ingrid; Sundström, Christer; Frost, Britt-Marie et al.

Ingår i Leukemia Research, s. 46-53, 2009

DOI för In vitro cellular drug sensitivity at diagnosis is correlated to minimal residual disease at end of induction therapy in childhood acute lymphoblastic leukemia

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

Milani, Lili; Lundmark, Anders; Nordlund, Jessica; Kiialainen, Anna et al.

Ingår i Genome Research, s. 1-11, 2009

DOI för Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

Lönnerholm, Gudmar; Valsecchi, Maria Grazia; De Lorenzo, Paola; Schrappe, Martin et al.

Ingår i Pediatric Blood & Cancer, s. 596-601, 2009

DOI för Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia

Vincristine pharmacokinetics in children with Down syndrome

Lönnerholm, Gudmar; Frost, Britt-Marie; Söderhäll, Stefan; de Graaf, Siebold S. N.

Ingår i Pediatric Blood & Cancer, s. 123-125, 2009

DOI för Vincristine pharmacokinetics in children with Down syndrome

Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids

Lönnerholm, Gudmar; Nordgren, A.; Frost, Britt-Marie; Jonsson, O. G. et al.

Ingår i Leukemia, s. 209-212, 2009

DOI för Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids

Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia

Palle, Josefine; Frost, Britt-Marie; Petersson, Curt; Hasle, Henrik et al.

Ingår i Anti-Cancer Drugs, s. 7-14, 2009

DOI för Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia

Bone marrow fibrosis in childhood acute lymphoblastic leukemia correlates to biological factors, treatment response and outcome

Norén-Nyström, Ulrika; Roos, G.; Bergh, A.; Botling, Johan et al.

Ingår i Leukemia, s. 504-510, 2008

DOI för Bone marrow fibrosis in childhood acute lymphoblastic leukemia correlates to biological factors, treatment response and outcome

Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia

Lönnerholm, Gudmar; Frost, Britt-Marie; Abrahamsson, Jonas; Behrendtz, Mikael et al.

Ingår i British Journal of Haematology, s. 616-21, 2008

DOI för Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia

Dendritic cell regeneration in the bone marrow of children treated for acute lymphoblastic leukaemia

Laane, E.; Björklund, E.; Mazur, J.; Lönnerholm, Gudmar et al.

Ingår i Scandinavian Journal of Immunology, s. 572-583, 2007

DOI för Dendritic cell regeneration in the bone marrow of children treated for acute lymphoblastic leukaemia

Etoposide pharmacokinetics in children treated for acute myeloid leukemia

Palle, Josefine; Frost, Britt-Marie; Gustafsson, Göran; Hellebostad, Marit et al.

Ingår i Anti-Cancer Drugs, s. 1087-1094, 2006

DOI för Etoposide pharmacokinetics in children treated for acute myeloid leukemia

High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.

von Bergh, Anne R M; van Drunen, Ellen; van Wering, Elisabeth R; van Zutven, Laura J C M et al.

Ingår i Genes Chromosomes Cancer, s. 731-9, 2006

Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemia

Frost, B M; Forestier, E; Gustafsson, G; Nygren, Peter et al.

Ingår i Leukemia, s. 165-169, 2005

DOI för Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemia

Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage.

Palle, J; Frost, B M; Forestier, E; Gustafsson, G et al.

Ingår i Br J Haematol, s. 189-98, 2005

Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia

Frost, Britt-Marie; Forestier, Erik; Gustafsson, Göran; Nygren, Peter et al.

Ingår i Blood, s. 2452-7, 2004

DOI för Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia

Pulmonary function after autologous bone marrow transplantation in children: a long-term prospective study

Frisk, Per; Arvidson, Johan; Bratteby, Lars-Eric; Hedenström, Hans et al.

Ingår i Bone Marrow Transplantation, s. 645-650, 2004

DOI för Pulmonary function after autologous bone marrow transplantation in children: a long-term prospective study

Growth post transplant. Pubertal development and final height after autologous bone marrow transplantation for acute lymphoblastic leukemia

Frisk, P; Arvidson, J; Gustafsson, J; Lönnerholm, G

Ingår i Bone Marrow Transplantation, s. 205-210, 2004

Increased in vitro cellular drug resistance is related to poor outcome in high-risk childhood acute lymphoblastic leukaemia

Frost, Britt-Marie; Nygren, Peter; Gustafsson, G; Forestier, E et al.

Ingår i British Journal of Haematology, s. 376-385, 2003

DOI för Increased in vitro cellular drug resistance is related to poor outcome in high-risk childhood acute lymphoblastic leukaemia

Pharmacokinetics of Doxorubicin in Children with Acute Lymphoblastic Leukemia: multi-institutional collaborative study

Frost, Britt-Marie; Eksborg, S; Björk, O; Abrahamsson, J et al.

Ingår i Medical and Pediatric Oncology, s. 329-337, 2002

DOI för Pharmacokinetics of Doxorubicin in Children with Acute Lymphoblastic Leukemia: multi-institutional collaborative study

In vitro activity of the novel cytotoxic agent CHS 828 in childhood acute leukemia

Frost, Britt-Marie; Lönnerholm, Gudmar; Nygren, Peter; Larsson, Rolf et al.

Ingår i Anti-Cancer Drugs, s. 735-742, 2002

Cataracts after autologous bone marrow transplantation in children

Frisk, Per; Hagberg, Hans; Mandahl, Agneta; Söderberg, Per et al.

Ingår i Acta Paediatrica, s. 814-819, 2000

DOI för Cataracts after autologous bone marrow transplantation in children

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