Pernilla Lagerbäck
Forskare vid Institutionen för medicinska vetenskaper; Infektionsmedicin
- Telefon:
- 018-611 34 80
- Mobiltelefon:
- 070-171 14 11
- E-post:
- pernilla.lagerback@medsci.uu.se
- Besöksadress:
- Akademiska sjukhuset
Infektion, ingång 34, 1 tr - Postadress:
- Akademiska sjukhuset
Infektion, ingång 34, 1 tr
751 85 Uppsala
- Akademiska meriter:
- PhD
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Publikationer
Senaste publikationer
- Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model (2024)
- Activity of polymyxin B combinations against genetically well-characterised Klebsiella pneumoniae producing NDM-1 and OXA-48-like carbapenemases (2023)
- Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments (2023)
- Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions (2023)
- Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48-and NDM-Producing Escherichia coli and Klebsiella pneumoniae (2022)
Alla publikationer
Artiklar
- Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model (2024)
- Activity of polymyxin B combinations against genetically well-characterised Klebsiella pneumoniae producing NDM-1 and OXA-48-like carbapenemases (2023)
- Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments (2023)
- Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time-kill experiments: high agreement with in silico predictions (2023)
- Evaluation of In Vitro Activity of Double-Carbapenem Combinations against KPC-2-, OXA-48-and NDM-Producing Escherichia coli and Klebsiella pneumoniae (2022)
- Human plasma protein levels alter the in vitro antifungal activity of caspofungin (2022)
- Interactions of polymyxin B in combination with aztreonam, minocycline, meropenem and rifampicin against Escherichia coli producing NDM and OXA-48-group carbapenemases (2021)
- Efficacy of Antibiotic Combinations against Multidrug-Resistant Pseudomonas aeruginosa in Automated Time-Lapse Microscopy and Static Time-Kill Experiments (2020)
- Evaluation of polymyxin B in combination with 13 other antibiotics against carbapenemase-producing Klebsiella pneumoniae in time-lapse microscopy and time-kill experiments (2020)
- Combination of polymyxin B and minocycline against multidrug-resistant Klebsiella pneumoniae (2020)
- Synergistic and bactericidal activities of mecillinam, amoxicillin and clavulanic acid combinations against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in 24-h time-kill experiments (2019)
- Reply to Prim et al., "Is Colistin Susceptibility Testing Finally on the Right Track?" (2018)
- Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli (2018)
- Automated time-lapse microscopy a novel method for screening of antibiotic combination effects against multidrug-resistant Gram-negative bacteria (2018)
- Colistin is Extensively Lost during Standard in Vitro Experimental Conditions (2017)
- Evaluation of automated time-lapse microscopy for assessment of in vitro activity of antibiotics (2017)
- Evaluation of antibacterial activities of colistin, rifampicin and meropenem combinations against NDM-1-producing Klebsiella pneumoniae in 24 h in vitro time-kill experiments (2016)
- A Novel Microfluidic Assay for Rapid Phenotypic Antibiotic Susceptibility Testing of Bacteria Detected in Clinical Blood Cultures (2016)
- A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants (2015)
- Evaluation of Double- and Triple-Antibiotic Combinations for VIM- and NDM-Producing Klebsiella pneumoniae by In Vitro Time-Kill Experiment (2014)
- Structure of bacteriophage T4 endonuclease II mutant E118A, a tetrameric GIY-YIG enzyme (2010)
- Bacteriophage T4 endonuclease II, a promiscuous GIY-YIG nuclease, binds as a tetramer to two DNA substrates (2009)
- Amino acid residues in the GIY-YIG endonuclease II of phage T4 affecting sequence recognition and binding as well as catalysis (2008)
- Bacteriophage T4 endonuclease II: concerted single-strand nicks yield double-strand cleavage. (2004)
- A framework to assess antibiotic effects using time-lapse microscopy
- Translational PKPD modelling and simulation framework to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae