Ernst H. Oliw

Catalytic and structural comparisons of fatty acid dioxygenases related to cyclooxygenases and peroxidases

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2025

• DOI för Catalytic and structural comparisons of fatty acid dioxygenases related to cyclooxygenases and peroxidases

Structural comparisons of bifunctional fatty acid dioxygenases with allene oxide, epoxy alcohol, or diol synthase activities

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2025

• DOI för Structural comparisons of bifunctional fatty acid dioxygenases with allene oxide, epoxy alcohol, or diol synthase activities

Thirty years with three-dimensional structures of lipoxygenases

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2024

• DOI för Thirty years with three-dimensional structures of lipoxygenases
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Iron and manganese lipoxygenases of plant pathogenic fungi and their role in biosynthesis of jasmonates

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2022

• DOI för Iron and manganese lipoxygenases of plant pathogenic fungi and their role in biosynthesis of jasmonates
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Diversity of the manganese lipoxygenase gene family - A mini-review

Oliw, Ernst H.

Ingår i Fungal Genetics and Biology, 2022

• DOI för Diversity of the manganese lipoxygenase gene family - A mini-review
• Ladda ner fulltext (pdf) av Diversity of the manganese lipoxygenase gene family - A mini-review

Fatty acid dioxygenase-cytochrome P450 fusion enzymes of filamentous fungal pathogens

Oliw, Ernst H.

Ingår i Fungal Genetics and Biology, 2021

• DOI för Fatty acid dioxygenase-cytochrome P450 fusion enzymes of filamentous fungal pathogens
• Ladda ner fulltext (pdf) av Fatty acid dioxygenase-cytochrome P450 fusion enzymes of filamentous fungal pathogens

Linoleate diol synthase related enzymes of the human pathogens Histoplasma capsulatum and Blastomyces dermatitidis

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2020

• DOI för Linoleate diol synthase related enzymes of the human pathogens Histoplasma capsulatum and Blastomyces dermatitidis
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Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

Oliw, Ernst H; Hamberg, Mats

Ingår i Rapid Communications in Mass Spectrometry, 2020

• DOI för Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

Fungal oxylipins direct programmed developmental switches in filamentous fungi

Niu, Mengyao; Steffan, Breanne N.; Fischer, Gregory J.; Venkatesh, Nandhitha et al.

Ingår i Nature Communications, 2020

• DOI för Fungal oxylipins direct programmed developmental switches in filamentous fungi
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Biosynthesis of Jasmonates from Linoleic Acid by the Fungus Fusarium oxysporum. Evidence for a Novel Allene Oxide Cyclase

Oliw, Ernst H; Hamberg, Mats

Ingår i Lipids, s. 543-556, 2019

• DOI för Biosynthesis of Jasmonates from Linoleic Acid by the Fungus Fusarium oxysporum. Evidence for a Novel Allene Oxide Cyclase

Product specificity of fungal 8R- and 9S-dioxygenases of the peroxidase-cyclooxygenase superfamily with amino acid derivatized polyenoic fatty acids

Oliw, Ernst H

Ingår i Archives of Biochemistry and Biophysics, s. 93-101, 2018

• DOI för Product specificity of fungal 8R- and 9S-dioxygenases of the peroxidase-cyclooxygenase superfamily with amino acid derivatized polyenoic fatty acids

Biosynthesis of Oxylipins by Rhizoctonia solani with Allene Oxide and Oleate 8S,9S-Diol Synthase Activities

Oliw, Ernst

Ingår i Lipids, s. 527-537, 2018

• DOI för Biosynthesis of Oxylipins by Rhizoctonia solani with Allene Oxide and Oleate 8S,9S-Diol Synthase Activities

Polyunsaturated C-18 fatty acids derivatized with Gly and Ile as an additional tool for studies of the catalytic evolution of fungal 8-and 9-dioxygenases

Oliw, E

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 1378-1387, 2018

• DOI för Polyunsaturated C-18 fatty acids derivatized with Gly and Ile as an additional tool for studies of the catalytic evolution of fungal 8-and 9-dioxygenases

An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum

Oliw, E; Hamberg, Mats

Ingår i Journal of Lipid Research, s. 1670-1680, 2017

• DOI för An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum

Purification and site-directed mutagenesis of linoleate 9S-dioxygenase-allene oxide synthase of Fusarium oxysporum confirms the oxygenation mechanism

Chen, Yang; Jernerén, Fredrik; Oliw, Ernst

Ingår i Archives of Biochemistry and Biophysics, s. 24-29, 2017

• DOI för Purification and site-directed mutagenesis of linoleate 9S-dioxygenase-allene oxide synthase of Fusarium oxysporum confirms the oxygenation mechanism

Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide

Sooman, Linda; Wennman, Anneli; Hamberg, Mats; Hoffmann, Inga et al.

Ingår i Biochimica et Biophysica Acta, s. 108-118, 2016

• DOI för Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide

Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe oryzae

Wennman, Anneli; Oliw, Ernst H.; Karkehabadi, Saeid; Chen, Yang

Ingår i Journal of Biological Chemistry, s. 8130-8139, 2016

• DOI för Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe oryzae

Crystal structure of linoleate 13R-manganese lipoxygenase in complex with an adhesion protein.

Chen, Yang; Wennman, Anneli; Karkehabadi, Saeid; Engström, Åke et al.

Ingår i Journal of Lipid Research, s. 1574-1588, 2016

• DOI för Crystal structure of linoleate 13R-manganese lipoxygenase in complex with an adhesion protein.

A functional role identified for conserved charged residues at the active site entrance of lipoxygenase with double specificity

Alberti, Jean-Christophe; Mariani, Magali; de Caraffa, Virginie Brunini-Bronzini; Gambotti, Claude et al.

Ingår i Journal of Molecular Catalysis B, s. 167-173, 2016

• DOI för A functional role identified for conserved charged residues at the active site entrance of lipoxygenase with double specificity

A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici.

Oliw, Ernst H; Aragó, Marc; Chen, Yang; Jernerén, Fredrik

Ingår i Journal of Lipid Research, s. 1518-1528, 2016

• DOI för A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici.

Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid

Wennman, Anneli; Jernerén, Fredrik; Magnuson, Ann; Oliw, Ernst H

Ingår i Archives of Biochemistry and Biophysics, s. 87-95, 2015

• DOI för Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid

Chiral phase-HPLC separation of hydroperoxyoctadecenoic acids and their biosynthesis by fatty acid dioxygenases.

Oliw, Ernst H; Wennman, Anneli

Ingår i Methods in Molecular Biology, s. 85-95, 2015

• DOI för Chiral phase-HPLC separation of hydroperoxyoctadecenoic acids and their biosynthesis by fatty acid dioxygenases.
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Manganese lipoxygenase of F. oxysporum and the structural basis for biosynthesis of distinct 11-hydroperoxy stereoisomers

Wennman, Anneli; Magnuson, Ann; Hamberg, Mats; Oliw, Ernst H.

Ingår i Journal of Lipid Research, s. 1606-1615, 2015

• DOI för Manganese lipoxygenase of F. oxysporum and the structural basis for biosynthesis of distinct 11-hydroperoxy stereoisomers

Discovery of a Novel Linoleate Dioxygenase of Fusarium oxysporum and Linoleate Diol Synthase of Colletotrichum graminicola

Sooman, Linda; Oliw, Ernst H.

Ingår i Lipids, s. 1243-1252, 2015

• DOI för Discovery of a Novel Linoleate Dioxygenase of Fusarium oxysporum and Linoleate Diol Synthase of Colletotrichum graminicola

Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes

Hoffmann, Inga; Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Journal of Lipid Research, s. 2113-2123, 2014

• DOI för Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes

Crystallization and preliminary crystallographic analysis of manganese lipoxygenase

Wennman, Anneli; Oliw, Ernst H.; Karkehabadi, Saeid

Ingår i Acta Crystallographica Section F, s. 522-525, 2014

• DOI för Crystallization and preliminary crystallographic analysis of manganese lipoxygenase

Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases

Wennman, Anneli; Karkehabadi, Saeid; Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, s. 9-15, 2014

• DOI för Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases

7,8- and 5,8-linoleate diol synthases support the heterolytic scission of oxygen-oxygen bonds by different amide residues.

Hoffmann, Inga; Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, s. 87-91, 2013

• DOI för 7,8- and 5,8-linoleate diol synthases support the heterolytic scission of oxygen-oxygen bonds by different amide residues.

Discovery of a linoleate 9S-dioxygenase and an allene oxide synthase in a fusion protein of Fusarium oxysporum

Hoffmann, Inga; Oliw, Ernst H.

Ingår i Journal of Lipid Research, s. 3417-3480, 2013

• DOI för Discovery of a linoleate 9S-dioxygenase and an allene oxide synthase in a fusion protein of Fusarium oxysporum

Secretion of two novel enzymes, manganese 9S-Lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii

Wennman, Anneli; Oliw, Ernst H

Ingår i Journal of Lipid Research, s. 762-775, 2013

• DOI för Secretion of two novel enzymes, manganese 9S-Lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii

Expression of Fusion Proteins of Aspergillus terreus Reveals a Novel Allene Oxide Synthase

Hoffmann, Inga; Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Journal of Biological Chemistry, s. 11459-11469, 2013

• DOI för Expression of Fusion Proteins of Aspergillus terreus Reveals a Novel Allene Oxide Synthase

Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs

Hoffmann, Inga; Hamberg, Mats; Lindh, Roland; Oliw, Ernst H.

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 1508-1517, 2012

• DOI för Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs

Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino Acid

Wennman, Anneli; Jernerén, Fredrik; Hamberg, Mats; Oliw, Ernst H

Ingår i Journal of Biological Chemistry, s. 31757-31765, 2012

• DOI för Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino Acid

The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB

Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Lipids, s. 707-717, 2012

• DOI för The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB

Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae

Jernerén, Fredrik; Eng, Felipe; Hamberg, Mats; Oliw, Ernst H

Ingår i Lipids, s. 65-73, 2012

• DOI för Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae

Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain: a comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase

Hoffmann, Inga; Jernerén, Fredrik; Garscha, Ulrike; Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, s. 216-222, 2011

• DOI för Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain: a comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase

Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms

Oliw, Ernst H.; Jernerén, Fredrik; Hoffmann, Inga; Sahlin, Margareta et al.

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 138-147, 2011

• DOI för Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms

Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases

Oliw, Ernst H.; Wennman, Anneli; Hoffmann, Inga; Garscha, Ulrike et al.

Ingår i Journal of Lipid Research, s. 1995-2004, 2011

• DOI för Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases

CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Pettersson, Hanna; Lundqvist, Johan; Oliw, Ernst; Norlin, Maria

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 1206-1215, 2009

• DOI för CYP7B1-mediated metabolism of 5 alfa-androstane-3 alfa,17 beta-diol (3 alfa-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids

Pichia expression of and mutagenesis of 7,8-linoleate diol synthase change the dioxygenase and hydroperoxide isomerase

Garscha, Ulrike; Oliw, Ernst

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 579-583, 2008

• DOI för Pichia expression of and mutagenesis of 7,8-linoleate diol synthase change the dioxygenase and hydroperoxide isomerase

Factors influencing the rearrangement of bis-allylic hydroperoxides by manganese lipoxygenase

Oliw, Ernst H

Ingår i Journal of Lipid Research, s. 420-428, 2008

• DOI för Factors influencing the rearrangement of bis-allylic hydroperoxides by manganese lipoxygenase

On the singular, dual, and multiple positional specificity of manganese lipoxygenase and its G316A mutant

Cristea, Mirela; Oliw, Ernst H.

Ingår i Journal of Lipid Research, s. 890-903, 2007

• DOI för On the singular, dual, and multiple positional specificity of manganese lipoxygenase and its G316A mutant

Identification of dioxygenases required for Aspergillus development: Studies of products, stereochemistry, and the reaction mechanism

Garscha, Ulrike; Jernerén, Fredrik; Chung, D.; Keller, N.P. et al.

Ingår i Journal of Biological Chemistry, s. 34707-34718, 2007

• DOI för Identification of dioxygenases required for Aspergillus development: Studies of products, stereochemistry, and the reaction mechanism

Steric analysis of 8-hydroxy- and 10-hydroxyoctadecadienoic acids and dihydroxyoctadecadienoic acids formed from 8R-hydroperoxyoctadecadienoic acid by hydroperoxide isomerases

Garscha, Ulrike; Oliw, Ernst H.

Ingår i Analytical Biochemistry, s. 238-246, 2007

• DOI för Steric analysis of 8-hydroxy- and 10-hydroxyoctadecadienoic acids and dihydroxyoctadecadienoic acids formed from 8R-hydroperoxyoctadecadienoic acid by hydroperoxide isomerases

Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1

Karlgren, M; Stark, Katarina; Svard, J; Rodriguez-Antona, C et al.

Ingår i Biochem Biophys Res Commun, s. 451-8, 2006

Payne rearrangement during analysis of epoxyalcohols of linoleic and a-linolenic acids by normal phase liquid chromatography with tandem mass spectrometry

Oliw, Ernst; Garscha, Ulrike; Nilsson, Tomas; Cristea, Mirela

Ingår i Anal. Biochem., s. 111-226, 2006

Gly316Ala mutation of manganese lipoxygenase augments hydroperoxide isomerase activity. Mechanism of biosynthesis of epoxyalcohols

Cristea, Mirela; Oliw, Ernst

Ingår i J. Biol. Chem., s. 17612-17623, 2006

Assessment of the effects of the cyclooxygenase-2 inhibitor rofecoxib on visuospatial learning and hippocampal cell death following kainate-induced seizures in the rat: Research Report

Kunz, Tina; Marklund, Niklas; Hillered, Lars; Oliw, Ernst H.

Ingår i Cognitive Brain Research, s. 826-832, 2005

• DOI för Assessment of the effects of the cyclooxygenase-2 inhibitor rofecoxib on visuospatial learning and hippocampal cell death following kainate-induced seizures in the rat: Research Report

Biosynthesis of epoxyeicosatrienoic acids varies between polymorphic CYP2C enzymes

Sandberg, M; Stark, K; Eliasson, E; Oliw, E et al.

Ingår i Biochem. Biophys. Res. Commun, s. 1052-1057, 2005

Cloning of the manganese lipoxygenase gene reveals homology with the lipoxygenase gene family

Hörnsten, Lena; Su, Chao; Osbourn, Anne E.; Hellman, Ulf et al.

Ingår i Eur. J. Biochem, s. 2690-7, 2002

Catalytic and structural comparisons of fatty acid dioxygenases related to cyclooxygenases and peroxidases

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2025

• DOI för Catalytic and structural comparisons of fatty acid dioxygenases related to cyclooxygenases and peroxidases

Structural comparisons of bifunctional fatty acid dioxygenases with allene oxide, epoxy alcohol, or diol synthase activities

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2025

• DOI för Structural comparisons of bifunctional fatty acid dioxygenases with allene oxide, epoxy alcohol, or diol synthase activities

Thirty years with three-dimensional structures of lipoxygenases

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2024

• DOI för Thirty years with three-dimensional structures of lipoxygenases
• Ladda ner fulltext (pdf) av Thirty years with three-dimensional structures of lipoxygenases

Iron and manganese lipoxygenases of plant pathogenic fungi and their role in biosynthesis of jasmonates

Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, 2022

• DOI för Iron and manganese lipoxygenases of plant pathogenic fungi and their role in biosynthesis of jasmonates
• Ladda ner fulltext (pdf) av Iron and manganese lipoxygenases of plant pathogenic fungi and their role in biosynthesis of jasmonates

Diversity of the manganese lipoxygenase gene family - A mini-review

Oliw, Ernst H.

Ingår i Fungal Genetics and Biology, 2022

• DOI för Diversity of the manganese lipoxygenase gene family - A mini-review
• Ladda ner fulltext (pdf) av Diversity of the manganese lipoxygenase gene family - A mini-review

Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids

Bylund, J; Oliw, E

1997