Magnus Essand

Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

Barbera, Stefano; Schuiling, Matthijs J. A.; Sanjaya, Nathaniel A.; Pietilä, Ilkka et al.

Ingår i Science immunology, 2025

• DOI för Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier

Martikainen, Miika; Lugano, Roberta; Pietilä, Ilkka; Brosch, Sofie et al.

Ingår i Nature Communications, 2024

• DOI för VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier
• Ladda ner fulltext (pdf) av VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier

Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response

Ali, Arwa; Contreras, Paola; Darweesh, Mahmoud; Andersson, Leif et al.

Ingår i Molecular Therapy Nucleic Acids, 2024

• DOI för Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response
• Ladda ner fulltext (pdf) av Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response

Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis

Aramesh, Morteza; Yu, Di; Essand, Magnus; Persson, Cecilia

Ingår i Advanced Functional Materials, 2024

• DOI för Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis
• Ladda ner fulltext (pdf) av Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Ingår i Cancer Cell, s. 1134-1151, 2023

• DOI för Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
• Ladda ner fulltext (pdf) av Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

Barbera, Stefano; Schuiling, Matthijs J. A.; Sanjaya, Nathaniel A.; Pietilä, Ilkka et al.

Ingår i Science immunology, 2025

• DOI för Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains

VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier

Martikainen, Miika; Lugano, Roberta; Pietilä, Ilkka; Brosch, Sofie et al.

Ingår i Nature Communications, 2024

• DOI för VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier
• Ladda ner fulltext (pdf) av VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier

Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response

Ali, Arwa; Contreras, Paola; Darweesh, Mahmoud; Andersson, Leif et al.

Ingår i Molecular Therapy Nucleic Acids, 2024

• DOI för Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response
• Ladda ner fulltext (pdf) av Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response

Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis

Aramesh, Morteza; Yu, Di; Essand, Magnus; Persson, Cecilia

Ingår i Advanced Functional Materials, 2024

• DOI för Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis
• Ladda ner fulltext (pdf) av Enhanced Cellular Uptake through Nanotopography-Induced Macropinocytosis

Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Ramachandran, Mohanraj; Vaccaro, Alessandra; van de Walle, Tiarne; Georganaki, Maria et al.

Ingår i Cancer Cell, s. 1134-1151, 2023

• DOI för Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
• Ladda ner fulltext (pdf) av Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Ingår i Clinical Cancer Research, s. 4139-4152, 2023

• DOI för Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients
• Ladda ner fulltext (pdf) av Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients

CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours

Kruse, Bastian; Buzzai, Anthony C.; Shridhar, Naveen; Braun, Andreas D. et al.

Ingår i Nature, s. 1033-1040, 2023

• DOI för CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours
• Ladda ner fulltext (pdf) av CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours

Complementarity-determining region clustering may cause CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Marti Torrell, Paula; Zhu, Xu et al.

Ingår i Nature Communications, 2023

• DOI för Complementarity-determining region clustering may cause CAR-T cell dysfunction
• Ladda ner fulltext (pdf) av Complementarity-determining region clustering may cause CAR-T cell dysfunction

CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Konstantinidis, Evangelos; Molisak, Agnieszka; Perrin, Florian; Streubel-Gallasch, Linn et al.

Ingår i Molecular Therapy Nucleic Acids, s. 450-461, 2022

• DOI för CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation
• Ladda ner fulltext (pdf) av CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Jin, Chuan; Ali, Arwa; Iskantar, Alexandros; Fotaki, Grammatiki et al.

Ingår i Oncoimmunology, 2022

• DOI för Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response
• Ladda ner fulltext (pdf) av Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-turnor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

Darweesh, Mahmoud; Younis, Shady; Hajikhezri, Zamaneh; Ali, Arwa et al.

Ingår i Frontiers in Immunology, 2022

• DOI för ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
• Ladda ner fulltext (pdf) av ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus

Iscaro, Alessandra; Jones, Christian; Forbes, Neil; Mughal, Amina et al.

Ingår i Nanomedicine, 2022

• DOI för Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus

Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Sjöholm, Therese; Korenyushkin, Alexander; Gammelgård, Gustav; Sarén, Tina et al.

Ingår i Cancer Imaging, 2022

• DOI för Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy
• Ladda ner fulltext (pdf) av Whole body FDG PET/MR for progression free and overall survival prediction in patients with relapsed/refractory large B-cell lymphomas undergoing CAR T-cell therapy

Ixovex-1, a novel oncolytic E1B-mutated adenovirus

Anwar, Mohiemen; Arendt, Maja-Louise; Ramachandran, Mohanraj; Carlsson, Anette et al.

Ingår i Cancer Gene Therapy, s. 1628-1635, 2022

• DOI för Ixovex-1, a novel oncolytic E1B-mutated adenovirus
• Ladda ner fulltext (pdf) av Ixovex-1, a novel oncolytic E1B-mutated adenovirus

CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

Jin, Chuan; Ma, Jing; Ramachandran, Mohanraj; Yu, Di et al.

Ingår i Nature Biomedical Engineering, s. 830-841, 2022

• DOI för CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers
• Ladda ner fulltext (pdf) av CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers

Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Deng, Siyuan; Iscaro, Alessandra; Zambito, Giorgia; Mijiti, Yimin et al.

Ingår i Nanomaterials, 2021

• DOI för Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy
• Ladda ner fulltext (pdf) av Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

van Hooren, Luuk; Vaccaro, Alessandra; Ramachandran, Mohanraj; Vazaios, Konstantinos et al.

Ingår i Nature Communications, 2021

• DOI för Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma
• Ladda ner fulltext (pdf) av Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Martikainen, Miika; Ramachandran, Mohanraj; Lugano, Roberta; Ma, Jing et al.

Ingår i MOLECULAR THERAPY-ONCOLYTICS, s. 37-46, 2021

• DOI för IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma
• Ladda ner fulltext (pdf) av IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Ingår i Circulation Research, s. 1694-1707, 2021

• DOI för Perivascular macrophages regulate blood flow following tissue damage

Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Quijano-Rubio, Clara et al.

Ingår i Cell Death and Disease, 2020

• DOI för Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer
• Ladda ner fulltext (pdf) av Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Rostami, Jinar; Fotaki, Grammatiki; Sirois, Julien; Mzezewa, Ropafadzo et al.

Ingår i Journal of Neuroinflammation, 2020

• DOI för Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain
• Ladda ner fulltext (pdf) av Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Depreter, Barbara; Weening, Karin E.; Vandepoele, Karl; Essand, Magnus et al.

Ingår i Haematologica, s. 1306-1316, 2020

• DOI för TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment
• Ladda ner fulltext (pdf) av TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

Ingår i Oncoimmunology, 2020

• DOI för Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
• Ladda ner fulltext (pdf) av Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean et al.

Ingår i Journal of Pathology, s. 228-240, 2019

• DOI för LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Čančer, Matko; Hutter, Sonja; Holmberg Olausson, Karl; Rosén, Gabriela et al.

Ingår i Cell Stem Cell, s. 855-870, 2019

• DOI för Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
• Ladda ner fulltext (pdf) av Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Lugano, Roberta; Vemuri, Kalyani; Yu, Di; Bergqvist, Michael et al.

Ingår i Journal of Clinical Investigation, s. 3280-3297, 2018

• DOI för CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
• Ladda ner fulltext (pdf) av CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018

• DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
• Ladda ner fulltext (pdf) av Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Enblad, Gunilla; Karlsson, Hannah; Gammelgård, Gustav; Wenthe, Jessica et al.

Ingår i Clinical Cancer Research, s. 6185-6194, 2018

• DOI för A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Fotaki, Grammatiki; Jin, Chuan; Ramachandran, Mohanraj; Kerzeli, Iliana Kyriaki et al.

Ingår i Oncoimmunology, 2018

• DOI för Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

Fotaki, Grammatiki; Jin, Chuan; Kerzeli, Iliana Kyriaki; Ramachandran, Mohanraj et al.

Ingår i Oncoimmunology, 2018

• DOI för Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models
• Ladda ner fulltext (pdf) av Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three melanoma models

Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors

Shridhar, N.; Ruotsalainen, J.; van der Sluis, T.; Rogava, M. et al.

Ingår i Experimental dermatology, 2018

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Ingår i European Journal of Clinical Investigation, s. 44-45, 2018

• DOI för Perivascular macrophages regulate blood flow following tissue damage

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Younis, Shady; Kamel, Wael; Falkeborn, Tina; Wang, Hao et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2018

• DOI för Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Ramachandran, Mohanraj; Yu, Di; Dyczynski, Matheus; Baskaran, Sathishkumar et al.

Ingår i Clinical Cancer Research, s. 1519-1530, 2017

• DOI för Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus

Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Yu, Di; Leja, Justyna; Loskog, Angelica S.; Hellman, Per et al.

Ingår i Neuroendocrinology, s. 54-66, 2017

• DOI för Preclinical Evaluation of AdVince, an Oncolytic Adenovirus Adapted for Treatment of Liver Metastases from Neuroendocrine Cancer

Adenovirus, Semliki Forest virus and vaccinia virus-induced immunogenic cell death augments oncolytic virus immunotherapy

Ma, Jing; Ramachandran, Mohanraj; Jin, Chuan; Essand, Magnus et al.

Ingår i Scandinavian Journal of Immunology, s. 341-341, 2017

Immunological biomarkers correlate to survival in CAR19-treated patients

Lövgren, Tanja; Wenthe, Jessica; Karlsson, S. C. Hannah; Gammelgård, Gustav et al.

Ingår i Scandinavian Journal of Immunology, s. 337-337, 2017

CAR T-Cells with Induced Secretion of Helicobacter Pylori Neutrophil-Activating Protein (HP-NAP) Yields Improved Anti-Tumor Activity and Reduced Immunosuppression

Essand, Magnus; Ma, Jing; Jin, Chuan; Ramachandran, Mohanraj et al.

Ingår i Molecular Therapy, s. 288-288, 2017

Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

Martikainen, Miika; Ruotsalainen, Janne; Tuomela, Johanna; Harkonen, Pirkko et al.

Ingår i British Journal of Cancer, s. 51-55, 2017

• DOI för Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

Pan, Gang; Ameur, Adam; Enroth, Stefan; Bysani, Madhusudhan et al.

Ingår i Nucleic Acids Research, s. 2408-2422, 2017

• DOI för PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c

miR-196a Is Specifically Regulated in FDG-PET Positive and Negative Small Intestinal Neuroendocrine Tumor Patients at Late Stage of Disease

Giandomenico, V; Li, Su-Chen; Lind, Thomas; Boccherini, M. et al.

Ingår i Neuroendocrinology, s. 115-115, 2016

Avidity characterization of genetically engineered T-cells with novel and established approaches

Hillerdal, Victoria; Boura, Vanessa F.; Björkelund, Hanna; Andersson, Karl et al.

Ingår i BMC Immunology, 2016

• DOI för Avidity characterization of genetically engineered T-cells with novel and established approaches
• Ladda ner fulltext (pdf) av Avidity characterization of genetically engineered T-cells with novel and established approaches

Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Kundu, Soumi; Xiong, Anqi; Spyrou, Argyris; Wicher, Grzegorz et al.

Ingår i Molecular Cancer Research, s. 1243-1253, 2016

• DOI för Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Wu, Chengjun; Cao, Xiaofang; Yu, Di; Huijbers, Elisabeth J. M. et al.

Ingår i Virology, s. 44-50, 2016

• DOI för HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice

Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Jin, Chuan; Yu, Di; Essand, Magnus

Ingår i Immunotherapy, s. 1355-1361, 2016

• DOI för Prospects to improve chimeric antigen receptor T-cell therapy for solid tumors

Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Fotaki, Grammatiki; Jin, Chuan; Karlsson-Parra, Alex; Yu, Di et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016

• DOI för Allogeneic dendritic cells (AlloDCs) transduced with an infection enhanced adenovirus as adjuvant for cancer immunotherapy

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

Jin, Chuan; Fotaki, Grammatiki; Ramachandran, Mohanraj; Nilsson, Berith et al.

Ingår i EMBO Molecular Medicine, s. 702-711, 2016

• DOI för Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer
• Ladda ner fulltext (pdf) av Safe engineering of CAR T cells for adoptive cell therapy of cancer using long-term episomal gene transfer

CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial

Enblad, Gunilla; Karlsson, Hannah; Wikström, Kristina I.; Essand, Magnus et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016

• DOI för CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia: report from the Swedish phase Ulla trial

Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Berith et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2016

• DOI för Long-term episomal gene transfer for safe engineering of T cells for adoptive cell therapy of cancer

A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia

Enblad, Gunilla; Karlsson, Hannah; Wenthe, Jessica; Wikström, Kristina I. et al.

Ingår i Molecular Therapy, 2016

Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Ingår i Cell Transplantation, s. 263-276, 2015

• DOI för Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Ingår i Science Signaling, 2015

• DOI för Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Ingår i Cell Transplantation, s. 263-276, 2015

• DOI för Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer

Hillerdal, Victoria; Essand, Magnus

Ingår i BioDrugs, s. 75-89, 2015

• DOI för Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer
• Ladda ner fulltext (pdf) av Chimeric Antigen Receptor-Engineered T Cells for the Treatment of Metastatic Prostate Cancer

Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Ingår i Cancer Research, s. 4504-4516, 2015

• DOI för Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Third Generation CD19-CAR T Cells for Relapsed and Refractory Lymphoma and Leukemia Report from the Swedish Phase I/IIa Trial

Enblad, Gunilla; Karlsson, Hannah; Wikström, Kristina; Essand, Magnus et al.

Ingår i Blood, 2015

Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Fransson, Moa; Brännström, Johan; Duprez, Ida; Essand, Magnus et al.

Ingår i Regenerative Medicine Research, 2015

• DOI för Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model
• Ladda ner fulltext (pdf) av Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Strategical steering of the immune system: induction of leukocyte vascular chaperoning increases functional blood flow responses in ischemic muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Ingår i The FASEB Journal, 2014

Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Schenk, Ellen; Essand, Magnus; Kraaij, Robert; Adamson, Rachel et al.

Ingår i Human Gene Therapy Clinical Development, s. 7-15, 2014

• DOI för Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Long-term episomal gene transfer for safe engineering of T-cells for adoptive cell therapy of cancer

Jin, Chuan; Ramachandran, Mohanraj; Fotaki, Grammatiki; Nilsson, Bo et al.

Ingår i Human Gene Therapy, 2014

Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Hillerdal, Victoria; Ramachandran, Mohanraj; Leja, Justyna; Essand, Magnus

Ingår i BMC Cancer, s. 30, 2014

• DOI för Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice
• Ladda ner fulltext (pdf) av Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet K.; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2014

Adenovirus Encoded Helicobacter pylori Neutrophil Activating Protein Promotes Maturation of DCs with Th-1 Polarization, Improved Antigen Presentation and Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Ingår i Molecular Therapy, 2014

Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Ramachandran, Mohanraj; Jin, Chuan; Yu, Di; Eriksson, Fredrik et al.

Ingår i Journal of Immunology, s. 2287-2296, 2014

• DOI för Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Liljenfeldt, Lina; Yu, Di; Chen, Liye; Essand, Magnus et al.

Ingår i Journal of immunotherapy (1997), s. 155-162, 2014

• DOI för A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Jin, Chuan; Yu, Di; Hillerdal, Victoria; Wallgren, AnnaCarin et al.

Ingår i Molecular Therapy Methods & Clinical Development, 2014

• DOI för Allogeneic lymphocyte-licensed DCs expand T cells withimproved antitumor activity and resistance to oxidative stress andimmunosuppressive factors

Engineering Regulatory Cells With a T Cell Receptor for Controlled Activation

Hillerdal, Victoria; Berglund, David; Boura, Vanessa; Jin, Chuan et al.

Ingår i Molecular Therapy, 2014

Allogeneic Lymphocyte-Licensed DCs Expand TCR/CAR-Engineered T Cells, Which Are Insensitive To Oxidative Stress and Immunosuppressive Factors

Jin, Chuan; Yu, Di; Karlsson-Parra, Alex; Essand, Magnus

Ingår i Molecular Therapy, 2014

An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Ramachandran, Mohanraj; Yu, Di; Wanders, Alkwin; Essand, Magnus et al.

Ingår i Molecular Therapy, s. 2008-2018, 2013

• DOI för An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors
• Ladda ner fulltext (pdf) av An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors

Virotherapy of Neuroendocrine Tumors

Essand, Magnus

Ingår i Neuroendocrinology, s. 26-34, 2013

• DOI för Virotherapy of Neuroendocrine Tumors

Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Ingår i PLOS ONE, 2013

• DOI för Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
• Ladda ner fulltext (pdf) av Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Karlsson, S. C. Hannah; Lindqvist, A. C.; Fransson, Moa; Paul-Wetterberg, Gabriella et al.

Ingår i Cancer Gene Therapy, s. 386-393, 2013

• DOI för Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Jin, Chuan; Yu, Di; Čančer, Matko; Nilsson, Berith et al.

Ingår i Human Gene Therapy, s. 766-775, 2013

• DOI för Tat‐PTD‐modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy
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Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation

Muthana, M.; Rodrigues, S.; Chen, Y. -Y; Welford, A. et al.

Ingår i Cancer Research, s. 490-495, 2013

• DOI för Macrophage delivery of an oncolytic virus abolishes tumor regrowth and metastasis after chemotherapy or irradiation

Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Molnár, Christian; Essand, Magnus; Wennberg, Lars; Berne, Christian et al.

Ingår i Cell Transplantation, s. 243-251, 2013

• DOI för Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2013

Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion

Vågesjö, Evalina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

Fransson, Moa; Piras, Elena; Burman, Joachim; Nilsson, Berith et al.

Ingår i Journal of Neuroinflammation, s. 112, 2012

• DOI för CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
• Ladda ner fulltext (pdf) av CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2⁺ prostate and breast cancer cells

Hillerdal, Victoria; Nilsson, Berith; Carlsson, Björn; Eriksson, Fredrik et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15877-15881, 2012

• DOI för T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2⁺ prostate and breast cancer cells

Age-related somatic structural changes in the nuclear genome of human blood cells

Forsberg, Lars A.; Rasi, Chiara; Razzaghian, Hamid R; Pakalapati, Geeta et al.

Ingår i American Journal of Human Genetics, s. 217-228, 2012

• DOI för Age-related somatic structural changes in the nuclear genome of human blood cells

In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

Adamson, R. E.; Frazier, A. A.; Evans, H.; Chambers, K. F. et al.

Ingår i Human Gene Therapy, s. 218-230, 2012

• DOI för In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication

Danielsson, Angelika; Dzojic, Helena; Rashkova, Victoria; Cheng, Wing-Shing et al.

Ingår i PLoS ONE, 2011

• DOI för The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication

Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors

Muthana, Munitta; Giannoudis, Athina; Scott, Simon D.; Fang, Hsin-Yu et al.

Ingår i Cancer Research, s. 1805-1815, 2011

• DOI för Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors

Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Leja, Justyna; Yu, Di; Nilsson, Berith; Gedda, Lars et al.

Ingår i Gene Therapy, s. 1052-1062, 2011

• DOI för Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors

Yu, Di; Jin, Chuan; Leja, Justyna; Majdalani, Nadim et al.

Ingår i Journal of Virology, s. 13114-13123, 2011

• DOI för Adenovirus with Hexon Tat-Protein Transduction Domain Modification Exhibits Increased Therapeutic Effect in Experimental Neuroblastoma and Neuroendocrine Tumors
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Generation of antigen-specific cytolytic T cells for prostate cancer therapy

Rashkova, Victoria; Essand, Magnus

Ingår i Human Gene Therapy, s. 1422-1422, 2010

Clinical Adenoviral Gene Therapy for Prostate Cancer

Schenk, Ellen; Essand, Magnus; Bangma, Chris

Ingår i Human Gene Therapy, s. 807-813, 2010

• DOI för Clinical Adenoviral Gene Therapy for Prostate Cancer

Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability

Leja, Justyna; Nilsson, Berith; Yu, Di; Gustafson, Elisabet et al.

Ingår i PLOS ONE, 2010

• DOI för Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability

Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

Maitland, Norman; Chambers, Karen; Georgopoulos, Lindsay; Simpson-Holley, Martha et al.

Ingår i Human Gene Therapy, s. 815-827, 2010

• DOI för Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Danielsson, Angelika; Elgue, Graciela; Nilsson, Berith M.; Nilsson, Bo et al.

Ingår i Gene Therapy, s. 752-762, 2010

• DOI för An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

Leja, Justyna; Essaghir, Ahmed; Essand, Magnus; Wester, Kenneth et al.

Ingår i Modern Pathology, s. 261-272, 2009

• DOI för Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue

Vikman, Sofia; Sommaggio, Roberta; De La Torre, Manuel; Öberg, Kjell et al.

Ingår i Acta Oncologica, s. 391-400, 2009

• DOI för Midgut carcinoid patients display increased numbers of regulatory T cells in peripheral blood with infiltration into tumor tissue
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High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals

Forsberg, Ole; Carlsson, Björn; Malmström, Per-Uno; Ullenhag, Gustav et al.

Ingår i The Prostate, s. 70-81, 2009

• DOI för High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals
• Ladda ner fulltext (pdf) av High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals

CD8(+) T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients

Vikman, Sofia; Giandomenico, Valeria; Sommaggio, Roberta; Öberg, Kjell et al.

Ingår i Cancer Immunology and Immunotherapy, s. 399-409, 2008

• DOI för CD8(+) T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients

Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells

Forsberg, Ole; Carlsson, Björn; Tötterman, Thomas H.; Essand, Magnus

Ingår i British Journal of Haematology, s. 188-199, 2008

• DOI för Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells
• Ladda ner fulltext (pdf) av Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells

CpG Therapy is Superior to BCG in an Orthotopic Bladder Cancer Model and Generates CD4+ T-cell Immunity

Mangsbo, Sara M; Ninalga, Christina; Essand, Magnus; Loskog, Angelica et al.

Ingår i Journal of immunotherapy (1997), s. 34-42, 2008

• DOI för CpG Therapy is Superior to BCG in an Orthotopic Bladder Cancer Model and Generates CD4+ T-cell Immunity

CpG oligonucleotides demonstrate increased therapeutic efficacy compared to BCG in an aggressive orthotopic bladder cancer model

Ninalga, Christina; Mangsbo, Sara; Loskog, Angelica; Essand, Magnus et al.

Ingår i Journal of immunotherapy (1997), s. 34-42, 2008

• DOI för CpG oligonucleotides demonstrate increased therapeutic efficacy compared to BCG in an aggressive orthotopic bladder cancer model

Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Danielsson, Angelika; Dzojic, H; Nilsson, B; Essand, M

Ingår i Cancer Gene Therapy, s. 203-213, 2008

• DOI för Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model

Dzojic, Helena; Cheng, Wing-Shing; Essand, Magnus

Ingår i Cancer Gene Therapy, s. 233-240, 2007

• DOI för Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model

Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy

Carlsson, Björn; Forsberg, Ole; Bengtsson, Mats; Tötterman, Thomas H. et al.

Ingår i The Prostate, s. 389-395, 2007

• DOI för Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy
• Ladda ner fulltext (pdf) av Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy

A novel chromogranin-A promoter-driven oncolytic adenovirus for midgut carcinoid therapy

Leja, Justyna; Dzojic, Helena; Gustafson, Elisabet; Öberg, Kjell et al.

Ingår i Clinical Cancer Research, s. 2455-2462, 2007

• DOI för A novel chromogranin-A promoter-driven oncolytic adenovirus for midgut carcinoid therapy

An oncolytic conditionally replicating adenovirus for hormone-dependent and hormone-independent prostate cancer

Cheng, Wing-Shing; Dzojic, Helena; Nilsson, Berith; Tötterman, Thomas H. et al.

Ingår i Cancer Gene Therapy, s. 13-20, 2006

• DOI för An oncolytic conditionally replicating adenovirus for hormone-dependent and hormone-independent prostate cancer

Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model

Dzojic, Helena; Loskog, Angelica; Tötterman, Thomas H.; Essand, Magnus

Ingår i The Prostate, s. 831-838, 2006

• DOI för Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model

Gene expression in midgut carcinoid tumors: potential targets for immunotherapy

Vikman, Sofia; Essand, Magnus; Cunningham, Janet L.; de la Torre, Manuel et al.

Ingår i Acta Oncologica, s. 32-40, 2005

• DOI för Gene expression in midgut carcinoid tumors: potential targets for immunotherapy

CpG oligonucleotide therapy cures subcutaneous and orthotopic tumors and evokes protective immunity in murine bladder cancer

Ninalga, Christina; Loskog, Angelica; Klevenfeldt, Magdalena; Essand, Magnus et al.

Ingår i Journal of immunotherapy (1997), s. 20-27, 2005

The immunotherapy of prostate and bladder cancer

Tötterman, Thomas H.; Loskog, Angelica; Essand, Magnus

Ingår i BJU International, s. 728-735, 2005

• DOI för The immunotherapy of prostate and bladder cancer

Gene therapy and immunotherapy of prostate cancer: adenoviral-based strategies.

Essand, Magnus

Ingår i Acta Oncol, s. 610-27, 2005

Adenovirus CD40 Ligand Gene Therapy Counteracts Immune Escape Mechanisms in the Tumor Microenvironment

Loskog, Angelica; Dzojic, Helena; Vikman, Sofia; Ninalga, Christina et al.

Ingår i Journal of Immunology, s. 7200-7205, 2004

Generation of cytotoxic T lymphocytes specific for the prostate and breast tissue antigen TARP

Carlsson, Björn; Tötterman, Thomas H.; Essand, Magnus

Ingår i The Prostate, s. 161-170, 2004

• DOI för Generation of cytotoxic T lymphocytes specific for the prostate and breast tissue antigen TARP

A novel TARP-promoter-based adenovirus against hormone-dependent and hormone-refractory prostate cancer

Cheng, Wing-Shing; Kraaij, Robert; Nilsson, Berith; van der Weel, Laura et al.

Ingår i Molecular Therapy, s. 355-364, 2004

• DOI för A novel TARP-promoter-based adenovirus against hormone-dependent and hormone-refractory prostate cancer

Ex vivo stimulation of cytomegalovirus (CMV)-specific T cells using CMVpp65-modified dendritic cells as stimulators

Carlsson, Björn; Cheng, Wing-Shing; Tötterman, Thomas H.; Essand, Magnus

Ingår i British Journal of Haematology, s. 428-38, 2003

• DOI för Ex vivo stimulation of cytomegalovirus (CMV)-specific T cells using CMVpp65-modified dendritic cells as stimulators

Characterization of the androgen-regulated prostate-specific T cellreceptor gamma-chain alternate reading frame protein (TARP) promoter.

Cheng, Wing-Shing; Giandomenico, Valeria; Pastan, Ira; Essand, Magnus

Ingår i Endocrinology, s. 3433-40, 2003

T cell receptor gamma chain alternate reading frame protein (TARP) expression in prostate cancer cells leads to an increased growth rate and induction of caveolins and amphiregulin.

Wolfgang, CD; Essand, Magnus; Lee, BK; Pastan, I

Ingår i Cancer Res., s. 8122-6, 2001

GDEP, a new gene differntially expressed in normal prostate and prostate cancer.

Olsson, Par; Bera, Tapan; Essand, Magnus; Kumar, V et al.

Ingår i Prostate, s. 231-41, 2001

Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer

Vaccaro, Alessandra; van de Walle, Tiarne; Ramachandran, Mohanraj; Essand, Magnus et al.

Ingår i Frontiers in Immunology, 2023

• DOI för Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
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Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

van de Walle, Tiarne; Vaccaro, Alessandra; Ramachandran, Mohanraj; Pietilä, Ilkka et al.

Ingår i Frontiers in Immunology, 2021

• DOI för Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma
• Ladda ner fulltext (pdf) av Tertiary Lymphoid Structures in the Central Nervous System: Implications for Glioblastoma

Virus-Based Immunotherapy of Glioblastoma

Martikainen, Miika; Essand, Magnus

Ingår i Cancers, 2019

• DOI för Virus-Based Immunotherapy of Glioblastoma
• Ladda ner fulltext (pdf) av Virus-Based Immunotherapy of Glioblastoma

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

Ramachandran, Mohanraj; Dimberg, Anna; Essand, Magnus

Ingår i Seminars in Cancer Biology, s. 23-35, 2017

• DOI för The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells
• Ladda ner fulltext (pdf) av The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells

Genetically engineered T cells for the treatment of cancer

Essand, Magnus; Loskog, Angelica S I

Ingår i Journal of Internal Medicine, s. 166-181, 2013

• DOI för Genetically engineered T cells for the treatment of cancer

Oncolytic Viruses for the Treatment of Neuroendocrine Tumors

Essand, Magnus; Leja, Justyna; Giandomenico, Valeria; Öberg, Kjell E.

Ingår i Hormone and Metabolic Research, s. 877-883, 2011

• DOI för Oncolytic Viruses for the Treatment of Neuroendocrine Tumors

Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy

Giandomenico, Valeria; Thirlwell, Chrissie; Essand, Magnus

Ingår i Neuroendocrine Tumors, s. 248-262, S. Karger, 2015

• DOI för Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy

Multiple viruses rely on the stress-induced protein ZC3H11A for efficient replication

Younis, Shady; Kamel, Wael; Wang, Hao; Yu, Di et al.

2017

Uncovering a new role for immune cells: macrophages assist in regulation of blood flow in ischemic muscle

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Korsgren, Olle et al.

Tumor antigen-loaded allogeneic dendritic cells augment therapeutic effect of adoptively transferred T-cells by altering tumor immune-microenvironment

Fotaki, Grammatiki; Jin, Chuan; Kerzeli, Iliana Kyriaki; Ramachandran, Mohanraj et al.

CD19 CAR T-cells with induced secretion of Helicobacter Pylori Neutrophil-Activating Protein (HP-NAP) yields improved anti-tumor activity and reduced immunosuppression

Jin, Chuan; Ma, Jing; Ramachandran, Mohanraj; Yu, Di et al.

Concomitant targeting of PD-1 or CD137 enhances the effect of adjuvant pro-inflammatory allogeneic dendritic cells.

Fotaki, Grammatiki; Yu, Di; Essand, Magnus; Karlsson-Parra, Alex

Therapeutic vaccination of HPV-associated tumors using pro-inflammatory allogeneic dendritic cells and an HPV-E6/E7-encoding vector

Fotaki, Grammatiki; Ma, Jing; Jin, Chuan; Karlsson-Parra, Alex et al.

Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients

Sarén, Tina; Ramachandran, Mohanraj; Gammelgård, Gustav; Lövgren, Tanja et al.

Armed CAR-T cells directed against IL13Rα2 show potent activity against glioblastoma

Sarén, Tina; Ramachandran, Mohanraj; Saronio, Giulia; Thelander, Josefin et al.

Preclinical evaluation of CAR20(NAP)-T cells for B cell lymphoma

Sarén, Tina; Ma, Jing; Jin, Chuan; Kim, Hyeongsu et al.

Complementary-determining region clustering causes CAR-T cell dysfunction

Sarén, Tina; Saronio, Giulia; Zhu, Xu; Thelander, Josefin et al.

CRISPR/Cas9 as a tool to disrupt wild-type and A53T SNCA in sporadic and familial Parkinson’s disease

Molisak, Agnieszka; Konstantinidis, Evangelos; Aguilar, Ximena; Giedraitis, Vilmantas et al.