CNSx3

CNSx3 is a national knowledge centre bringing together leading researchers and innovators to develop the next generation of human brain models. The goal is to advance personalised treatment strategies for brain diseases by integrating biotechnology, microfluidics, data science, and clinical research.

At the heart of the centre’s work are brain organoids — miniature, three-dimensional models of human brain tissue — embedded in microfluidic chips to mimic the brain’s complex environment. These models are connected to national biobanks and patient-derived samples, enabling detailed studies of diseases like glioblastoma, paediatric brain tumours, and vascular malformations in the brain.

Through real-time imaging and AI-guided analytics, CNSx3 researchers explore how to tailor therapies dynamically — optimising not only what drugs are used, but also when and how they are administered for maximum effect.

The centre also runs a national research school for PhD students and postdocs, offering training in organoid technology, ethics, microfluidics, and data-driven methods. With strong ties to healthcare, industry, and patient organisations, CNSx3 aims to ensure that research leads to tangible impact.

CNSx3 is coordinated by Uppsala University in collaboration with five academic institutions, two industrial partners, and a broad national network of affiliated researchers. The centre is funded by the Swedish Foundation for Strategic Research (SSF).

Related information

Centre for Person-Centred Brain Models and Therapies website