Functional Pharmacology and Neuroscience
The research group of Functional Pharmacology and Neuroscience conducts pharmacological, toxicological, genetic, and behavioral studies related to drugs, environmental toxins, diseases, behaviors, and environmental changes.
The research group use several experimental models, including humans and animals such as flies and mice. They investigate the side effects of drugs to understand the molecular, cell specific and genetic causes behind their toxic effects. They examine the mechanisms of environmental toxins impact, in connection with several diseases and identify blood biomarkers for diagnosing different conditions. They study various types of behaviors, such as food intake and addiction, and attempt to elucidate the molecular mechanisms. They also map large gene and protein families as well as molecular signaling pathways.
The group has an interdisciplinary environment that promotes career opportunities for doctoral students and postdoctoral fellows. They are a highly productive unit with several high-quality publications and significant citations and the PI is one of the most cited researcher in the world. Their teachers teach on the medical program, the biomedical program, the master's program in biomedicine, and other relevant courses.
Group members
Publications
Part of Frontiers in Neuroscience, 2024
Part of Polymers, 2024
Part of Frontiers in Psychiatry, 2024
- DOI for Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
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Association of combined healthy lifestyle with risk of adverse outcomes in patients with prediabetes
Part of Diabetes/Metabolism Research Reviews, 2024
Part of Scientific Reports, 2024
- DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
- Download full text (pdf) of Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
Part of Neuroscience and Biobehavioral Reviews, 2024
Part of BMC Public Health, 2024
Giardia telomeres and telomerase
Part of Parasitology Research, 2024
Part of Journal of medical systems, 2024
2024
Part of Cancer Letters, 2024
- DOI for STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
- Download full text (pdf) of STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
The Pattern of GH Action in the Mouse Brain
Part of Endocrinology, 2024
Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
Part of Frontiers in Psychiatry, 2024
The profiles of social anxiety and impulsivity among college students: differences in aggression
Part of Current Psychology, p. 10621-10630, 2024
Idiopathic granulomatous orchitis: A case study
Part of Urology Case Reports, 2024
Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2024
GHSR in a Subset of GABA Neurons Controls Food Deprivation-Induced Hyperphagia in Male Mice
Part of Endocrinology, 2024
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
Part of Nature Communications, 2024
A deep learning model for brain age prediction using minimally preprocessed T1w images as input
Part of Frontiers in Aging Neuroscience, 2024
Part of EBioMedicine, 2024
- DOI for Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
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Part of Translational Psychiatry, 2024
Part of Frontiers in Psychology, 2024
- DOI for Differentiating the relationships between traditional and new media use and sleep quality during the COVID-19 pandemic: roles of psychological distress and age
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Part of Journal of the Neurological Sciences, 2024
- DOI for Developing education in environmental health and medicine focusing on neurology: Initiatives in Sweden (the UPRISE model), France, and Turkey
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Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
Part of Translational Psychiatry, 2024
Part of Translational Psychiatry, 2024
Part of Diabetes, obesity and metabolism, 2024
Aging insights from heterochronic parabiosis models
Part of NPJ AGING, 2024
Part of Molecular Autism, 2024
Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
Part of COMPREHENSIVE PSYCHONEUROENDOCRINOLOGY, 2024
Part of Frontiers in Psychiatry, 2024
- DOI for Good parent-child relationship protects against alcohol use in maltreated adolescent females carrying the MAOA-uVNTR susceptibility allele
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Part of International Journal of Molecular Sciences, 2023
Part of Clinical Epigenetics, 2023
Part of Age and Ageing, 2023
Investigating mental health disorders in relation to job and living related factors
2023
Part of Neuroendocrinology, p. 64-79, 2023
Part of Reproduction, p. 123-134, 2023
Part of Biomedicines, 2023
- DOI for Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
- Download full text (pdf) of Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
Part of Journal of Clinical Medicine, 2023
Ghrelin proteolysis increases in plasma of men, but not women, with obesity
Part of Life Sciences, 2023
Part of Clinica Chimica Acta, 2023
Part of Frontiers in Psychology, 2023
Job satisfaction has differential associations with delay discounting and risk-taking
Part of Scientific Reports, 2023
Part of Hematological Oncology, p. 26-38, 2023
- DOI for DNA damage accumulation and repair defects in FLT3‐ITD acute myeloid leukemia: Implications for clonal evolution and disease progression
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Part of Journal of personality, p. 856-867, 2023
- DOI for Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
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Part of Journal of Applied Toxicology, p. 458-469, 2023
- DOI for Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
- Download full text (pdf) of Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
Mind & Well-being: The relationships between personality and health related pathology
2023
Part of Alimentary Pharmacology and Therapeutics, p. 475-485, 2023
Part of Frontiers in Psychology, 2023
Part of BMC Psychology, 2023
- DOI for Relationship between leadership-member exchange (LMX) and flow at work among medical workers during the COVID-19: the mediating role of job crafting
- Download full text (pdf) of Relationship between leadership-member exchange (LMX) and flow at work among medical workers during the COVID-19: the mediating role of job crafting
Part of International Journal of Molecular Sciences, 2023