Functional Pharmacology and Neuroscience

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties

Muslim, Wisam Taher; Mohammad, Layth Jasim; Naji, Munaf M.; Karimi, Isaac et al.

Part of Frontiers in Pharmacology, 2025

• DOI for Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
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Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank

Xiao, Shanshan; Ebner, Natalie C.; Dang, Junhua; Rukh, Gull et al.

Part of Cortex, p. 211-219, 2025

• DOI for Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
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A Haplotype GWAS in Syndromic Familial Colorectal Cancer

Vermani, Litika; Winnberg, Johanna Samola; Liu, Wen; Soller, Veronika et al.

Part of International Journal of Molecular Sciences, 2025

• DOI for A Haplotype GWAS in Syndromic Familial Colorectal Cancer
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Critical Insights Into LEAP2 Biology and Physiological Functions: Potential Roles Beyond Ghrelin Antagonism

Perello, Mario

Part of Endocrinology, 2025

• DOI for Critical Insights Into LEAP2 Biology and Physiological Functions: Potential Roles Beyond Ghrelin Antagonism

Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism

Mohammad, Salahuddin; Bussu, Giorgia; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Cephalalgia, p. 1-12, 2025

• DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review

Karimi, Isaac; Ghowsi, Mahnaz; Mohammed, Layth Jasim; Haidari, Zohreh et al.

Part of Polymers, 2025

• DOI for Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review
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GPCR drug discovery: new agents, targets and indications

Lorente, Javier Sánchez; Sokolov, Aleksandr V.; Ferguson, Gavin; Schiöth, Helgi et al.

Part of Nature reviews. Drug discovery, 2025

• DOI for GPCR drug discovery: new agents, targets and indications

Identification of candidate biomarkers in neurological and psychiatric health

Lafta, Muataz

2025

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Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments

Kosheleva, Liudmila; Koshelev, Daniil; Lagunas-Rangel, Francisco Alejandro; Levit, Shmuel et al.

Part of Pharmacological Reviews, 2025

• DOI for Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments
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Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations

Vekhova, Ksenia A.; Namiot, Eugenia D.; Jonsson, Jörgen; Schiöth, Helgi

Part of Clinical Pharmacology and Therapeutics, p. 374-386, 2025

• DOI for Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations
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Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology

Karimi, Isaac; Mohammad, Layth Jasim; Suvitha, A.; Haidari, Zohreh et al.

Part of Frontiers in Toxicology, 2025

• DOI for Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology
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New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI

Wang, Hu; Li, Yanru; Chen, Shuai; Yan, Jie et al.

Part of Sensors and actuators. B, Chemical, 2025

• DOI for New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI
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Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

Sun, Chenggong; Li, Xiao; Teng, Qiuli; Liu, Xihan et al.

Part of Theranostics, p. 3055-3075, 2025

• DOI for Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

The relationship between national identity and public health support needs to be reconsidered

Dang, Junhua; Du, Hongfei; Ma, Zhihao; Xu, Lili et al.

Part of Frontiers in Psychology, 2025

• DOI for The relationship between national identity and public health support needs to be reconsidered
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Exploring the effects of long-term physical exercise on persistent and inhibitory self-control: quasi-experimental research

Cheng, Linjing; Qin, Huahui; Yang, Yin; Dang, Junhua

Part of Frontiers in Sports and Active Living, 2025

• DOI for Exploring the effects of long-term physical exercise on persistent and inhibitory self-control: quasi-experimental research
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Giardia fibrillarin: a bioinformatics exploration of sequence and structure

Lagunas-Rangel, Francisco Alejandro

Part of Journal of Applied Genetics, p. 241-248, 2025

• DOI for Giardia fibrillarin: a bioinformatics exploration of sequence and structure
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Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Peng, Lu; Sun, Rui; Hao, Tingting; Mu, Yulong et al.

Part of Molecular Medicine Reports, 2025

• DOI for Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer
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Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Lafta, Muataz S.; Mwinyi, Jessica; Affatato, Oreste; Rukh, Gull et al.

Part of Frontiers in Neuroscience, 2024

• DOI for Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi

Part of Polymers, 2024

• DOI for Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery
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Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Part of Scientific Reports, 2024

• DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)

Brooks, Samantha; Dahl, K.; Dudley-Jones, R.; Schiöth, Helgi

Part of Neuroscience and Biobehavioral Reviews, 2024

• DOI for A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
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Giardia telomeres and telomerase

Lagunas-Rangel, Francisco Alejandro

Part of Parasitology Research, 2024

• DOI for Giardia telomeres and telomerase
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Learning with AI Language Models: Guidelines for the Development and Scoring of Medical Questions for Higher Education

Moulin, Thiago C.

Part of Journal of medical systems, 2024

• DOI for Learning with AI Language Models: Guidelines for the Development and Scoring of Medical Questions for Higher Education

Beating of hammers

Affatato, Oreste

2024

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STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Liu, Jiale; Liu, Chenmian; Ma, Yana; Pan, Xiyu et al.

Part of Cancer Letters, 2024

• DOI for STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
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The Pattern of GH Action in the Mouse Brain

Menezes, Filipe; Wasinski, Frederick; de Souza, Gabriel O.; Nunes, Amanda P. et al.

Part of Endocrinology, 2024

• DOI for The Pattern of GH Action in the Mouse Brain

Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

Gentreau, Melissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura et al.

Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2024

• DOI for Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers

Smith-Byrne, Karl; Hedman, Åsa; Dimitriou, Marios; Desai, Trishna et al.

Part of Nature Communications, 2024

• DOI for Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
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Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Desai, Trishna A.; Hedman, Asa K.; Dimitriou, Marios; Koprulu, Mine et al.

Part of EBioMedicine, 2024

• DOI for Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Mohammad, Salahuddin; Gentreau, Mélissa; Dubol, Manon; Rukh, Gull et al.

Part of Molecular Autism, 2024

• DOI for Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
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Deciphering Adult Autism: Exploring Polygenic Risk, Brain Structure, Well-being, Migraine, and Mental Health Disorders

Mohammad, Salahuddin

2024

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Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer

Wu, Huan; Sun, Chenggong; Cao, Wenyu; Teng, Qiuli et al.

Part of Cancer Letters, 2024

• DOI for Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer
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Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales

Bondarev, Andrey D.; Jonsson, Jörgen; Chubarev, Vladimir N.; V. Tarasov, Vadim et al.

Part of Pharmacological Research, 2024

• DOI for Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales
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The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Rafeletou, Alexandra; Niemi, Jenni; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Part of Science of the Total Environment, 2024

• DOI for The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Biomarkers for depression: genetic, epigenetic, and expression evidence

Sokolov, Aleksandr V.

2024

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Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons

Hosseini, Kimia; Cediel Ulloa, Andrea; Al-Sabri, Mohamed H.; Forsby, Anna et al.

Part of Pharmaceuticals, 2024

• DOI for Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons
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Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Sokolov, Aleksandr V.; Schiöth, Helgi

Part of Translational Psychiatry, 2024

• DOI for Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
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Aging insights from heterochronic parabiosis models

Lagunas-Rangel, Francisco Alejandro

Part of NPJ AGING, 2024

• DOI for Aging insights from heterochronic parabiosis models
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Role of circular RNAs in DNA repair

Lagunas-Rangel, Francisco Alejandro

Part of RNA Biology, p. 149-161, 2024

• DOI for Role of circular RNAs in DNA repair
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Exploration of Giardia small nucleolar RNAs (snoRNAs) and their possible microRNA derivatives

Lagunas-Rangel, Francisco Alejandro

Part of Parasitology, p. 539-545, 2024

• DOI for Exploration of Giardia small nucleolar RNAs (snoRNAs) and their possible microRNA derivatives
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Advances in development of biomarkers for brain damage and ischemia

Karimova, Diana; Rostami, Elham; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Part of Molecular Biology Reports, 2024

• DOI for Advances in development of biomarkers for brain damage and ischemia
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Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells.

Liao, Sifang; Sun, Chengxi; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Part of Science of the Total Environment, p. 177472, 2024

• DOI for Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells.

Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes

Gentreau, Mélissa; Miguet, Maud; Affatato, Oreste; Rukh, Gull et al.

Part of Brain Communications, 2024

• DOI for Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
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Effects of psychedelics on neurogenesis and broader neuroplasticity: a systematic review

Lima da Cruz, Rafael V.; Leão, Richardson N.; Moulin, Thiago C.

Part of Molecular Medicine, 2024

• DOI for Effects of psychedelics on neurogenesis and broader neuroplasticity: a systematic review
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Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects

Vermani, Litika; Barnekow, Elin; Liu, Wen; Wendt, Camilla et al.

Part of Genes, 2024

• DOI for Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects
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Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Manzke Glänzel, Nícolas; Teixeira da Rosa-Junior, Nevton; Signori, Marian F.; de Andrade Silveira, Josyane et al.

Part of Metabolic brain disease, 2024

• DOI for Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Aguggia, Julieta; Fernandez, Gimena; Cassano, Daniela; Mustafá, Emilio R. et al.

Part of Endocrinology, 2024

• DOI for Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain

Saenz, Camila; Fernandez, Gimena; Llovera, Ramiro; Tolosa, María J. et al.

Part of Brain Structure and Function, 2024

• DOI for Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain
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Diagnosis and Treatment of Bronchopulmonary Lophomoniasis in a Patient with Persistent Granuloma: A Case Report

Mier-Briseno, Antonio; Ramirez-Alanis, Eloisa; Benavides-Huerto, Miguel Armando; Lagunas-Rangel, Francisco Alejandro

Part of REPORTS, 2024

• DOI for Diagnosis and Treatment of Bronchopulmonary Lophomoniasis in a Patient with Persistent Granuloma: A Case Report
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Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls

Lafta, Muataz S; Sokolov, Aleksandr V.; Landtblom, Anne-Marie; Ericson, Hans et al.

Part of European Journal of Pain, p. 929-942, 2024

• DOI for Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
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