Ophthalmology
The ophthalmology unit has research projects in several of the subspecialities of ophthalmology.
The ophthalmology unit has research projects in several of the subspecialities of ophthalmology with a focus on clinical glaucoma research, pediatric ophthalmology, cataract surgery, vitreoretinal surgery, diagnosis and medical treatment of retinal disease, and interaction of ultraviolett, visible and infrared radiation and the eye.
The methodology spans from experimental research in the Gullstrand lab to applied clinical research in the ophthalmology clinic at Akademiska sjukhuset, with collaborations in USA, and Germany.
Teaching
The ophthalmology unit at the Department of Surgical sciences is responsible for the academic activity of ophthalmology at Uppsala university. The academic activity is directly associated with the ophthalmology hospital care at the Ophthalmology, Uppsala University Hospital.
The ophthalmology unit is responsible for the undergraduate teaching of ophthalmology to:
- The MD-program, including 2 courses per year of totally around 200 students
- The Biomedicine program including 1 kurs per year of totally 50 students
- The Advanced Neurobiology Masters course. 1 course per year.
The unit is also responsible for organizing courses on
- Physiological optics
- Pediatric ophthalmology
in the Swedish national residency program.
History
The ophthalmology unit was founded as the Dept. of Ophthalmology by professor Alvar Gullstrand who was the first chair of ophthalmology at Uppsala University, appointed in 1894. Allvar Gullstrand was in 1911 awarded the Noble prize in medicine and physiology for his work on the optics of the eye. Alvar Gullstrand, in 1914 was appointed a personal professorship in physical and physiological optics. Professor e.m. Albert Alm, in close collaboration with the Uppsala company Pharmacia Ophthalmics, directed the clinical development of latanoprost, the first molecule in a new generation of drugs for reduction of intraocular pressure, that now is a market leader in many parts of the world. Professor e.m. Gerd Holmström was one of the founders of the Swedish Retinopathy of prematurity register. Results from Gerds Holmström's research group has contributed to protocols for clinical follow up of retinopathy of prematurity internationally.
Group members
Publications
Expression of active caspase 3 in the rat lens after in vivo exposure to subthreshold dose of UVR-B
Part of BMC Ophthalmology, 2024
Part of Neuroradiology, p. 145-154, 2024
Part of BMC Ophthalmology, 2024
Intraocular Pressure and Cerebrospinal Fluid: An Intricate Relationship
Part of Journal of neuro-ophthalmology, 2024
Part of British Journal of Ophthalmology, p. 137-142, 2024
Aggregatibacter Endophthalmitis in a patient with Dentophobia
Part of Retinal cases & brief reports, p. 135-137, 2024
Part of Acta Ophthalmologica, p. 91-98, 2024
2023
Part of Acta Paediatrica, p. 1537-1547, 2023
Part of Acta Ophthalmologica, p. 530-535, 2023
Assessing the safety of new germicidal far‐UVC technologies
Part of Photochemistry and Photobiology, 2023
Part of Global Pediatrics, 2023
- DOI for Skin conductance measurement as a selective and continuous pain assessment method during eye examinations for retinopathy of prematurity
- Download full text (pdf) of Skin conductance measurement as a selective and continuous pain assessment method during eye examinations for retinopathy of prematurity
Part of Acta Ophthalmologica, p. 1-10, 2023
- DOI for Central macular morphology and optic nerve fibre layer thickness in young adults born premature and screened for retinopathy of prematurity
- Download full text (pdf) of Central macular morphology and optic nerve fibre layer thickness in young adults born premature and screened for retinopathy of prematurity
Prognostic Value of Parenteral Nutrition Duration on Risk of Retinopathy of Prematurity
Part of JAMA ophthalmology, p. 716-716, 2023
Part of Acta Ophthalmologica, 2023
Distribution of cup-disc ratio in a Swedish population
Part of Upsala Journal of Medical Sciences, 2023
Part of Acta Ophthalmologica, 2023
Part of Neuropsychological rehabilitation (Print), p. 346-355, 2023
- DOI for Suppressing visual hallucinations in an adolescent by occipital transcranial magnetic stimulation: A single-case experimental research design
- Download full text (pdf) of Suppressing visual hallucinations in an adolescent by occipital transcranial magnetic stimulation: A single-case experimental research design
Part of British Journal of Ophthalmology, 2022
- DOI for Validation of DIGIROP models and decision support tool for prediction of treatment for retinopathy of prematurity on a contemporary Swedish cohort
- Download full text (pdf) of Validation of DIGIROP models and decision support tool for prediction of treatment for retinopathy of prematurity on a contemporary Swedish cohort
Retinopathy of prematurity classification updates: possible implications for treatment
Part of Journal of AAPOS, p. 109-112, 2022
Distribution of intraocular pressure in a Swedish population
Part of Upsala Journal of Medical Sciences, 2022
Part of British Journal of Ophthalmology, p. 1573-1580, 2022
Part of Brain Communications, 2022
Visual tracking at 4 months in preterm infants predicts 6.5-year cognition and attention
Part of Pediatric Research, p. 1082-1089, 2022
Part of Acta Ophthalmologica Scandinavica, 2022
Part of Acta Ophthalmologica, p. 189-195, 2022
Part of Acta Paediatrica, p. 1515-1525, 2022
- DOI for National cohort of infants born before 24 gestational weeks showed increased survival rates but no improvement in neonatal morbidity
- Download full text (pdf) of National cohort of infants born before 24 gestational weeks showed increased survival rates but no improvement in neonatal morbidity
Part of Acta Ophthalmologica, p. 769-774, 2022
- DOI for What about the fellow eye in treatment of neovascular age‐related macular degeneration? Analysis of data from the Swedish macula register
- Download full text (pdf) of What about the fellow eye in treatment of neovascular age‐related macular degeneration? Analysis of data from the Swedish macula register
Antenatal steroids and neurodevelopment in 12‐year‐old children born extremely preterm
Part of Acta Paediatrica, p. 314-322, 2022
Part of Frontiers in Neurology, 2022
- DOI for Case Report: Cerebrospinal Fluid Dynamics in the Optic Nerve Subarachnoid Space and the Brain Applying Diffusion Weighted MRI in Patients With Idiopathic Intracranial Hypertension-A Pilot Study
- Download full text (pdf) of Case Report: Cerebrospinal Fluid Dynamics in the Optic Nerve Subarachnoid Space and the Brain Applying Diffusion Weighted MRI in Patients With Idiopathic Intracranial Hypertension-A Pilot Study
Part of BMJ Open, 2022
- DOI for Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age in a Swedish cohort
- Download full text (pdf) of Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age in a Swedish cohort
Part of OPHTHALMIC TECHNOLOGIES XXXII, 2022
2021
Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study
Part of Investigative Ophthalmology and Visual Science, 2021
Part of Child's Nervous System, p. 3891-3895, 2021
- DOI for Acute disseminated encephalomyelitis with delayed onset and feasibility of the Miethke shunt and sensor reservoir system: a case report
- Download full text (pdf) of Acute disseminated encephalomyelitis with delayed onset and feasibility of the Miethke shunt and sensor reservoir system: a case report
Part of Acta Paediatrica, p. 846-854, 2021
- DOI for Average 2.5-year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age
- Download full text (pdf) of Average 2.5-year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age
CIE 245:2021, Optical safety of infrared eye trackers applied for extended durations
2021
Part of Acta Paediatrica, p. 838-845, 2021
International Classification of Retinopathy of Prematurity, Third Edition
Part of Ophthalmology, p. 51-68, 2021
Part of Proceedings Volume 11623, Ophthalmic Technologies XXXI, 2021
Part of JAMA Network Open, 2021
- DOI for Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity Among Preterm Infants
- Download full text (pdf) of Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity Among Preterm Infants
Part of BMJ Open Ophthalmology, 2021
- DOI for Ophthalmological findings in children with non-syndromic craniosynostosis preoperatively and postoperatively up to 12 months after surgery
- Download full text (pdf) of Ophthalmological findings in children with non-syndromic craniosynostosis preoperatively and postoperatively up to 12 months after surgery
Part of BMJ Open Ophthalmology, 2021
- DOI for High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born < 24 gestational weeks
- Download full text 1 (pdf) of High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born < 24 gestational weeks
- Download full text 2 (pdf) of High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born < 24 gestational weeks
Part of Eye and Brain, p. 157-158, 2021
- DOI for Are Generalized Reduced Cerebrospinal Fluid Dynamics and Optic Nerve Sheath Compartmentation Sequential Steps in the Pathogenesis of Normal-Tension Glaucoma?
- Download full text (pdf) of Are Generalized Reduced Cerebrospinal Fluid Dynamics and Optic Nerve Sheath Compartmentation Sequential Steps in the Pathogenesis of Normal-Tension Glaucoma?
Part of Eye and Brain, p. 89-97, 2021
- DOI for Lipocalin-type Prostaglandin D Synthase Concentration Gradients in the Cerebrospinal Fluid in Normal-tension Glaucoma Patients with Optic Nerve Sheath Compartmentation
- Download full text (pdf) of Lipocalin-type Prostaglandin D Synthase Concentration Gradients in the Cerebrospinal Fluid in Normal-tension Glaucoma Patients with Optic Nerve Sheath Compartmentation
Part of Ophthalmic Epidemiology, p. 301-305, 2021
Part of Acta Paediatrica, p. 127-133, 2021
Part of Clinical neurology and neurosurgery, 2021
Comment on: The role of intracranial pressure in glaucoma
Part of Eye (London. 1987), p. 1793-1793, 2021
Part of Upsala Journal of Medical Sciences, 2021