Oftalmologi

Foto: Elin Eriksson
Den oftalmologiska forskargruppen har forskningsprojekt inom flera av oftalmologins subspecialiteter.
Den oftalmologiska forskargruppen har forskningsprojekt inom flera av oftalmologins subspecialiteter med fokus på klinisk glaukomforskning, pediatrisk oftalmologi, kataraktkirurgi, vitreoretinal kirurgi, diagnos och medicinsk behandling av retinala sjukdomar samt interaktion mellan ultraviolett, synlig och infraröd strålning och ögat. Metodiken spänner från experimentell forskning i Gullstrands labb till tillämpad klinisk forskning på ögonkliniken vid Akademiska sjukhuset, med samarbeten i USA och Tyskland.
Undervisning
Forskargruppen ansvarar för grundutbildningen i oftalmologi:
- MD-programmet, inklusive 2 kurser per år med totalt cirka 200 studenter
- Biomedicinprogrammet, inklusive 1 kurs per år med totalt 50 studenter
- Masterkursen i avancerad neurobiologi. 1 kurs per år.
Enheten ansvarar också för att organisera kurser i det svenska nationella ST-programmet inom:
- Fysiologisk optik
- Pediatrisk oftalmologi
Samarbeten
Den oftalmologiska forskargruppen vid institutionen ansvarar för den akademiska verksamheten inom oftalmologi vid Uppsala universitet. Den akademiska verksamheten är direkt kopplad till den oftalmologiska sjukhusvården vid Ögonkliniken, Akademiska sjukhuset i Uppsala.
Historik
Den oftalmologiska enheten grundades av professor Alvar Gullstrand som var den första professorn i oftalmologi vid Uppsala universitet, utnämnd 1894. Alvar Gullstrand tilldelades 1911 Nobelpriset i medicin och fysiologi för sitt arbete med ögats optik. Alvar Gullstrand utnämndes 1914 till personlig professur i fysikalisk och fysiologisk optik. Professor e.m. Albert Alm ledde i nära samarbete med Uppsalaföretaget Pharmacia Ophthalmics den kliniska utvecklingen av latanoprost, den första molekylen i en ny generation läkemedel för sänkning av det intraokulära trycket, som nu är marknadsledande i många delar av världen. Professor e.m. Gerd Holmström var en av grundarna till det svenska registret för Retinopathy of prematurity. Resultat från Gerds Holmströms forskargrupp har bidragit till protokoll för klinisk uppföljning av retinopati vid prematuritet internationellt.
Gruppmedlemmar
Publikationer
Automatic segmentation for early glaucoma detection using nnU-Net
Ingår i SPIE Proc., 2025
Ingår i SPIE Proc., 2025
Ingår i BMJ Open Ophthalmology, 2025
- DOI för Screening for retinopathy of prematurity (ROP) in South Africa: data from a newly established prospective regional register
- Ladda ner fulltext (pdf) av Screening for retinopathy of prematurity (ROP) in South Africa: data from a newly established prospective regional register
Expression of active caspase 3 in the rat lens after in vivo exposure to subthreshold dose of UVR-B
Ingår i BMC Ophthalmology, 2024
- DOI för Expression of active caspase 3 in the rat lens after in vivo exposure to subthreshold dose of UVR-B
- Ladda ner fulltext (pdf) av Expression of active caspase 3 in the rat lens after in vivo exposure to subthreshold dose of UVR-B
Intraocular Pressure and Cerebrospinal Fluid: An Intricate Relationship
Ingår i Journal of neuro-ophthalmology, 2024
Ingår i British Journal of Ophthalmology, s. 137-142, 2024
- DOI för Ophthalmological outcome of 6.5 years children treated for retinopathy of prematurity: a Swedish register study
- Ladda ner fulltext (pdf) av Ophthalmological outcome of 6.5 years children treated for retinopathy of prematurity: a Swedish register study
Aggregatibacter Endophthalmitis in a patient with Dentophobia
Ingår i Retinal cases & brief reports, s. 135-137, 2024
Ingår i Acta Ophthalmologica, s. 91-98, 2024
- DOI för Automatic estimation of the cross-sectional area of the waist of the nerve fiber layer at the optic nerve head
- Ladda ner fulltext (pdf) av Automatic estimation of the cross-sectional area of the waist of the nerve fiber layer at the optic nerve head
Ingår i Eye (London. 1987), s. 2575-2580, 2024
- DOI för Age related cerebrospinal fluid flow dynamics in the subarachnoid space of the optic nerve in patients with normal tension glaucoma, measured by diffusion weighted MRI
- Ladda ner fulltext (pdf) av Age related cerebrospinal fluid flow dynamics in the subarachnoid space of the optic nerve in patients with normal tension glaucoma, measured by diffusion weighted MRI
Ingår i European Radiology, s. 1736-1745, 2024
- DOI för Acute and long-term renal effects after iodine contrast media-enhanced computerised tomography in the critically ill: a retrospective bi-centre cohort study
- Ladda ner fulltext (pdf) av Acute and long-term renal effects after iodine contrast media-enhanced computerised tomography in the critically ill: a retrospective bi-centre cohort study
Ingår i Neuroradiology, s. 145-154, 2024
- DOI för Brain MRI findings and their association with visual impairment in young adolescents born very preterm
- Ladda ner fulltext (pdf) av Brain MRI findings and their association with visual impairment in young adolescents born very preterm
Incidence of blindness in open-angle glaucoma in Sweden: a long-term follow-up study
Ingår i Upsala Journal of Medical Sciences, 2024
- DOI för Incidence of blindness in open-angle glaucoma in Sweden: a long-term follow-up study
- Ladda ner fulltext (pdf) av Incidence of blindness in open-angle glaucoma in Sweden: a long-term follow-up study
Ingår i BMC Ophthalmology, 2024
- DOI för The impact of COVID-19 on aflibercept treatment of neovascular AMD in Sweden: data from the Swedish Macula Register
- Ladda ner fulltext (pdf) av The impact of COVID-19 on aflibercept treatment of neovascular AMD in Sweden: data from the Swedish Macula Register
Ingår i Journal of Plastic Surgery and Hand Surgery, s. 162-170, 2024
- DOI för Variations in orbital morphology, globe:orbit volume relation, and ophthalmological outcome in unicoronal synostosis
- Ladda ner fulltext (pdf) av Variations in orbital morphology, globe:orbit volume relation, and ophthalmological outcome in unicoronal synostosis
Assessing the safety of new germicidal far‐UVC technologies
Ingår i Photochemistry and Photobiology, s. 501-520, 2024
2023
Ingår i Acta Ophthalmologica, s. 530-535, 2023
Ingår i Global Pediatrics, 2023
- DOI för Skin conductance measurement as a selective and continuous pain assessment method during eye examinations for retinopathy of prematurity
- Ladda ner fulltext (pdf) av Skin conductance measurement as a selective and continuous pain assessment method during eye examinations for retinopathy of prematurity
Ingår i Acta Ophthalmologica, s. 1-10, 2023
- DOI för Central macular morphology and optic nerve fibre layer thickness in young adults born premature and screened for retinopathy of prematurity
- Ladda ner fulltext (pdf) av Central macular morphology and optic nerve fibre layer thickness in young adults born premature and screened for retinopathy of prematurity
Prognostic Value of Parenteral Nutrition Duration on Risk of Retinopathy of Prematurity
Ingår i JAMA ophthalmology, s. 716-716, 2023
Ingår i Acta Ophthalmologica, 2023
- DOI för Strabismus and refraction in non‐syndromic craniosynostosis: – A longitudinal study up to 5 years of age
- Ladda ner fulltext (pdf) av Strabismus and refraction in non‐syndromic craniosynostosis: – A longitudinal study up to 5 years of age
Ingår i Acta Ophthalmologica, 2023
Ingår i Neuropsychological rehabilitation (Print), s. 346-355, 2023
- DOI för Suppressing visual hallucinations in an adolescent by occipital transcranial magnetic stimulation: A single-case experimental research design
- Ladda ner fulltext (pdf) av Suppressing visual hallucinations in an adolescent by occipital transcranial magnetic stimulation: A single-case experimental research design
Ingår i British Journal of Ophthalmology, s. 1132-1138, 2023
- DOI för Validation of DIGIROP models and decision support tool for prediction of treatment for retinopathy of prematurity on a contemporary Swedish cohort
- Ladda ner fulltext (pdf) av Validation of DIGIROP models and decision support tool for prediction of treatment for retinopathy of prematurity on a contemporary Swedish cohort
Ingår i Acta Paediatrica, s. 1537-1547, 2023
- DOI för Different aspects of visual perception are important for 12-year social functioning depending on gestational age
- Ladda ner fulltext (pdf) av Different aspects of visual perception are important for 12-year social functioning depending on gestational age
Distribution of cup-disc ratio in a Swedish population
Ingår i Upsala Journal of Medical Sciences, 2023
- DOI för Distribution of cup-disc ratio in a Swedish population
- Ladda ner fulltext (pdf) av Distribution of cup-disc ratio in a Swedish population
Retinopathy of prematurity classification updates: possible implications for treatment
Ingår i Journal of AAPOS, s. 109-112, 2022
Ingår i British Journal of Ophthalmology, s. 1573-1580, 2022
- DOI för Development and validation of a new clinical decision support tool to optimize screening for retinopathy of prematurity
- Ladda ner fulltext (pdf) av Development and validation of a new clinical decision support tool to optimize screening for retinopathy of prematurity
Ingår i Brain Communications, 2022
- DOI för Elevated perioptic lipocalin-type prostaglandin D synthase concentration in patients with idiopathic intracranial hypertension
- Ladda ner fulltext (pdf) av Elevated perioptic lipocalin-type prostaglandin D synthase concentration in patients with idiopathic intracranial hypertension
Visual tracking at 4 months in preterm infants predicts 6.5-year cognition and attention
Ingår i Pediatric Research, s. 1082-1089, 2022
Ingår i Acta Ophthalmologica Scandinavica, 2022
- DOI för Strabismus, stereoacuity, accommodation and convergence in young adults born premature and screened for retinopathy of prematurity
- Ladda ner fulltext (pdf) av Strabismus, stereoacuity, accommodation and convergence in young adults born premature and screened for retinopathy of prematurity
Ingår i Acta Ophthalmologica, s. 189-195, 2022
- DOI för Refraction and its development in young adults born prematurely and screened for retinopathy of prematurity.
- Ladda ner fulltext (pdf) av Refraction and its development in young adults born prematurely and screened for retinopathy of prematurity.
Ingår i Acta Paediatrica, s. 1515-1525, 2022
- DOI för National cohort of infants born before 24 gestational weeks showed increased survival rates but no improvement in neonatal morbidity
- Ladda ner fulltext (pdf) av National cohort of infants born before 24 gestational weeks showed increased survival rates but no improvement in neonatal morbidity
Ingår i Acta Ophthalmologica, s. 769-774, 2022
- DOI för What about the fellow eye in treatment of neovascular age‐related macular degeneration? Analysis of data from the Swedish macula register
- Ladda ner fulltext (pdf) av What about the fellow eye in treatment of neovascular age‐related macular degeneration? Analysis of data from the Swedish macula register
Antenatal steroids and neurodevelopment in 12‐year‐old children born extremely preterm
Ingår i Acta Paediatrica, s. 314-322, 2022
- DOI för Antenatal steroids and neurodevelopment in 12‐year‐old children born extremely preterm
- Ladda ner fulltext (pdf) av Antenatal steroids and neurodevelopment in 12‐year‐old children born extremely preterm
Ingår i Frontiers in Neurology, 2022
- DOI för Case Report: Cerebrospinal Fluid Dynamics in the Optic Nerve Subarachnoid Space and the Brain Applying Diffusion Weighted MRI in Patients With Idiopathic Intracranial Hypertension-A Pilot Study
- Ladda ner fulltext (pdf) av Case Report: Cerebrospinal Fluid Dynamics in the Optic Nerve Subarachnoid Space and the Brain Applying Diffusion Weighted MRI in Patients With Idiopathic Intracranial Hypertension-A Pilot Study
Ingår i BMJ Open, 2022
- DOI för Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age in a Swedish cohort
- Ladda ner fulltext (pdf) av Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age in a Swedish cohort
Ingår i OPHTHALMIC TECHNOLOGIES XXXII, 2022
Distribution of intraocular pressure in a Swedish population
Ingår i Upsala Journal of Medical Sciences, 2022
- DOI för Distribution of intraocular pressure in a Swedish population
- Ladda ner fulltext (pdf) av Distribution of intraocular pressure in a Swedish population
2021
Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study
Ingår i Investigative Ophthalmology and Visual Science, 2021
- DOI för Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study
- Ladda ner fulltext (pdf) av Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study
Ingår i Child's Nervous System, s. 3891-3895, 2021
- DOI för Acute disseminated encephalomyelitis with delayed onset and feasibility of the Miethke shunt and sensor reservoir system: a case report
- Ladda ner fulltext (pdf) av Acute disseminated encephalomyelitis with delayed onset and feasibility of the Miethke shunt and sensor reservoir system: a case report
Ingår i Acta Paediatrica, s. 846-854, 2021
- DOI för Average 2.5-year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age
- Ladda ner fulltext (pdf) av Average 2.5-year neurodevelopmental test results in children born very preterm did not rule out cognitive deficits at 6.5 years of age
CIE 245:2021, Optical safety of infrared eye trackers applied for extended durations
2021
Ingår i Acta Paediatrica, s. 838-845, 2021
- DOI för Using different definitions affected the reported prevalence of neurodevelopmental impairment in children born very preterm
- Ladda ner fulltext (pdf) av Using different definitions affected the reported prevalence of neurodevelopmental impairment in children born very preterm
International Classification of Retinopathy of Prematurity, Third Edition
Ingår i Ophthalmology, s. 51-68, 2021
Ingår i Proceedings Volume 11623, Ophthalmic Technologies XXXI, 2021
Ingår i JAMA Network Open, 2021
- DOI för Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity Among Preterm Infants
- Ladda ner fulltext (pdf) av Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity Among Preterm Infants
Ingår i BMJ Open Ophthalmology, 2021
- DOI för Ophthalmological findings in children with non-syndromic craniosynostosis preoperatively and postoperatively up to 12 months after surgery
- Ladda ner fulltext (pdf) av Ophthalmological findings in children with non-syndromic craniosynostosis preoperatively and postoperatively up to 12 months after surgery
Ingår i BMJ Open Ophthalmology, 2021
- DOI för High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born < 24 gestational weeks
- Ladda ner fulltext 1 (pdf) av High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born < 24 gestational weeks
- Ladda ner fulltext 2 (pdf) av High rate and large intercentre variability in retreatment of retinopathy of prematurity in infants born < 24 gestational weeks