Öron-, näs- och halskirurgi
Huvud-halsområdet är ett av kroppens mest komplexa områden när det kommer till anatomi och funktion.
Huvud-halsområdet omfattar många vitala strukturer som påverkar vår livskvalitet såsom sinnesorgan för hörsel, balans, lukt och smak, och andning, röst, svälj- och tuggfunktioner samt även ansiktets mimik och sensorisk. Halsen inbegriper även rösten som är ett viktigt instrument i den mänskliga kommunikationen. Dessa funktioner kan påverkas av såväl sjukdomar samt den behandling som ges.
Forskningen inom detta område inbegriper såväl grundforskning som strävar till ökad förståelse för organs anatomi och funktion som kliniska behandlingsstudier. Det grundläggande syftet är att öka kunskapen om sjukdomar och deras förlopp för att kunna förbättra behandlingen för den enskilde patienten.
På dessa sidor presenteras en överblick av de olika forskningsområden och projekt som pågår just nu.
Pågående forskning:
Gruppmedlemmar
Publikationer
Ingår i International Journal of Pediatric Otorhinolaryngology, 2024
- DOI för Estimated prevalence of permanent hearing loss among newborns and 6-year-olds: An evaluation of the three auditory screenings in Uppsala
- Ladda ner fulltext (pdf) av Estimated prevalence of permanent hearing loss among newborns and 6-year-olds: An evaluation of the three auditory screenings in Uppsala
Ingår i Supportive Care in Cancer, 2024
- DOI för Mapping the impact of malnutrition as defined by the Global Leadership Initiative on Malnutrition and nutrition impact symptoms on the possibility of returning to work after treatment for head and neck cancer
- Ladda ner fulltext (pdf) av Mapping the impact of malnutrition as defined by the Global Leadership Initiative on Malnutrition and nutrition impact symptoms on the possibility of returning to work after treatment for head and neck cancer
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Ingår i Nature Communications, 2024
Vestibular schwannoma: Clinical, Epidemiological and Biochemical perspectives
2024
Inner ear proteomics and barriers: Clinical and experimental findings
2024
Ingår i Plastic and reconstructive surgery (1963), 2024
Ingår i Oral Oncology, 2024
- DOI för Human papillomavirus (HPV) load is higher in HPVDNA/p16 positive than in HPVDNA positive/p16 negative oropharyngeal squamous cell carcinoma but does not differ significantly between various subsites or correlate to survival
- Ladda ner fulltext (pdf) av Human papillomavirus (HPV) load is higher in HPVDNA/p16 positive than in HPVDNA positive/p16 negative oropharyngeal squamous cell carcinoma but does not differ significantly between various subsites or correlate to survival
Systemic inflammation and prognostic markers in patients with head and neck cancer
2024
Immuno-surveillance and protection of the human cochlea
Ingår i Frontiers in Neurology, 2024
Ingår i PLOS ONE, 2024
Ingår i iScience, 2024
Ingår i BMC Cancer, 2024
- DOI för The effect of internet-administered support (carer eSupport) on preparedness for caregiving in informal caregivers of patients with head and neck cancer compared with support as usual: a study protocol for a randomized controlled trial
- Ladda ner fulltext (pdf) av The effect of internet-administered support (carer eSupport) on preparedness for caregiving in informal caregivers of patients with head and neck cancer compared with support as usual: a study protocol for a randomized controlled trial
Fall-related injury among patients with vestibular schwannoma
Ingår i PLOS ONE, 2024
Ingår i Digital Health and Informatics Innovations for Sustainable Health Care Systems, s. 751-755, 2024
- DOI för A Qualitative Study with Informal Caregivers and Healthcare Professionals for Individuals with Head and Neck Cancer on the Usage of AI Chatbots
- Ladda ner fulltext (pdf) av A Qualitative Study with Informal Caregivers and Healthcare Professionals for Individuals with Head and Neck Cancer on the Usage of AI Chatbots
Ingår i Scientific Reports, 2024
- DOI för Hearing loss and its association with the proteome of perilymph, cerebrospinal fluid, and tumor tissue in patients with vestibular schwannoma
- Ladda ner fulltext (pdf) av Hearing loss and its association with the proteome of perilymph, cerebrospinal fluid, and tumor tissue in patients with vestibular schwannoma
Accuracy of p16 IHC in Classifying HPV-Driven OPSCC in Different Populations
Ingår i Cancers, 2023
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Loco-Regional Control and Sustained Difference in Serum Immune Protein Expression in Patients Treated for p16-Positive and p16-Negative Head and Neck Squamous Cell Carcinoma
- Ladda ner fulltext (pdf) av Loco-Regional Control and Sustained Difference in Serum Immune Protein Expression in Patients Treated for p16-Positive and p16-Negative Head and Neck Squamous Cell Carcinoma
Do Patients Aged 85 Years and above Benefit from Their Cochlear Implants?
Ingår i Audiology Research, s. 96-106, 2023
Ingår i Frontiers in Cell and Developmental Biology, 2023
Ingår i The Lancet Oncology, s. 239-251, 2023
- DOI för Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
- Ladda ner fulltext (pdf) av Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
Factors that affect quality of life for older people with head and neck cancer: A systematic review
Ingår i European Journal of Oncology Nursing, 2023
Ingår i Scientific Reports, 2023
Intrasellar Pressure is Related to Endocrine Disturbances in Patients with Pituitary Tumors
Ingår i World Neurosurgery, 2023
Ingår i Journal of Clinical Sleep Medicine (JCSM), s. 573-579, 2023
Ingår i Oral Oncology, 2023
Ingår i JAMA Otolaryngology - Head and Neck Surgery, s. 390-396, 2023
Regulatory B cells producing IL-10 are increased in human tumor draining lymph nodes
Ingår i International Journal of Cancer, s. 854-866, 2023
Ingår i Scandinavian Journal of Medicine and Science in Sports, s. 1509-1518, 2023
Ingår i European Journal of Oncology Nursing, 2023
- DOI för Perceptions of life and experiences of health care support among individuals one year after head and neck cancer treatment-An interview study
- Ladda ner fulltext (pdf) av Perceptions of life and experiences of health care support among individuals one year after head and neck cancer treatment-An interview study
Ingår i Nature Communications, 2023
Ingår i Austin Journal of Dentistry, s. 1174-1174, 2023
Ingår i Cancers, s. 4705-4705, 2023
Ingår i Scientific Reports, 2023
- DOI för Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer
- Ladda ner fulltext (pdf) av Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer
Ingår i Heliyon, 2023
Ingår i European Journal of Oncology Nursing, 2023
- DOI för Understanding the challenges and need for support of informal caregivers to individuals with head and neck cancer - A basis for developing internet-based support
- Ladda ner fulltext (pdf) av Understanding the challenges and need for support of informal caregivers to individuals with head and neck cancer - A basis for developing internet-based support
National Knowledge-Driven Management of Obstructive Sleep Apnea: The Swedish Approach
Ingår i Diagnostics, 2023
Ingår i Cancers, 2023
- DOI för High Levels of FGF11 Correlate with Poor Survival in Patients with Human Papillomavirus (HPV)-Positive Oropharyngeal Squamous Cell Carcinoma
- Ladda ner fulltext (pdf) av High Levels of FGF11 Correlate with Poor Survival in Patients with Human Papillomavirus (HPV)-Positive Oropharyngeal Squamous Cell Carcinoma
Ingår i International Wound Journal, s. 120-130, 2023
Ingår i Cancer Medicine, s. 12524-12534, 2023
The impact of waiting time on hearing outcome and patients' satisfaction after cholesteatoma surgery
Ingår i Acta Oto-Laryngologica, s. 662-668, 2023
Ingår i Oral surgery, oral medicine, oral pathology and oral radiology, s. 691-702, 2023
Ingår i Clinical Otolaryngology, s. 895-901, 2023
Ingår i JMIR Cancer, 2023
- DOI för Positive Design Framework for Carer-eSupport: A Qualitative Study to Support Informal Caregivers of Patients with Head and Neck Cancer in Sweden
- Ladda ner fulltext (pdf) av Positive Design Framework for Carer-eSupport: A Qualitative Study to Support Informal Caregivers of Patients with Head and Neck Cancer in Sweden
Auditory brainstem implant pitch discrimination and auditory outcome
Ingår i ACTA OTO-LARYNGOLOGICA CASE REPORTS, s. 39-43, 2022
Ingår i Cancers, 2022
- DOI för Longitudinal Changes in the Fatty Acid Profile in Patients with Head and Neck Cancer: Associations with Treatment and Inflammatory Response
- Ladda ner fulltext (pdf) av Longitudinal Changes in the Fatty Acid Profile in Patients with Head and Neck Cancer: Associations with Treatment and Inflammatory Response
Ingår i Acta Oncologica, s. 433-440, 2022
- DOI för Base of tongue squamous cell carcinomas, outcome depending on treatment strategy and p16 status. A population-based study from the Swedish Head and Neck Cancer Register
- Ladda ner fulltext (pdf) av Base of tongue squamous cell carcinomas, outcome depending on treatment strategy and p16 status. A population-based study from the Swedish Head and Neck Cancer Register
Ingår i Frontiers in Molecular Neuroscience, 2022
- DOI för GJB2 and GJB6 gene transcripts in the human cochlea: A study using RNAscope, confocal, and super-resolution structured illumination microscopy
- Ladda ner fulltext (pdf) av GJB2 and GJB6 gene transcripts in the human cochlea: A study using RNAscope, confocal, and super-resolution structured illumination microscopy
Pediatric Obstructive Sleep Apnea: Evaluation of surgical treatments and immunological aspects
2022
Ingår i Cancers, 2022
Unlocking the human inner ear for therapeutic intervention
Ingår i Scientific Reports, 2022