Otorhinolaryngology and Head and Neck Surgery
The head and neck area is one of the most complex parts when it comes to anatomy and function.
The head and neck area is one of the most complex parts when it comes to anatomy and function. The area includes many vital structures that affect our quality of life such as sensory organs for hearing, balance, smell and taste, as well as breathing, swallowing, voice and facial mimicry and sensory. These functions can be affected both by diseases and by the treatment.
Research in the field of Otorhinolaryngology and Head and Neck surgery includes basic research that strives for increased understanding of organ anatomy and function as well as clinical treatment studies. The basic purpose is to increase knowledge about diseases and their course to improve treatment for the individual patient. These pages present an overview of the various research areas and projects that are ongoing at the Unit for Ear, Nose and Throat Diseases, Head and Neck Surgery.
Research fields
Group members
Publications
Part of International Journal of Pediatric Otorhinolaryngology, 2024
- DOI for Estimated prevalence of permanent hearing loss among newborns and 6-year-olds: An evaluation of the three auditory screenings in Uppsala
- Download full text (pdf) of Estimated prevalence of permanent hearing loss among newborns and 6-year-olds: An evaluation of the three auditory screenings in Uppsala
Part of Supportive Care in Cancer, 2024
- DOI for Mapping the impact of malnutrition as defined by the Global Leadership Initiative on Malnutrition and nutrition impact symptoms on the possibility of returning to work after treatment for head and neck cancer
- Download full text (pdf) of Mapping the impact of malnutrition as defined by the Global Leadership Initiative on Malnutrition and nutrition impact symptoms on the possibility of returning to work after treatment for head and neck cancer
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Part of Nature Communications, 2024
Vestibular schwannoma: Clinical, Epidemiological and Biochemical perspectives
2024
Inner ear proteomics and barriers: Clinical and experimental findings
2024
Part of Plastic and reconstructive surgery (1963), 2024
Part of Oral Oncology, 2024
- DOI for Human papillomavirus (HPV) load is higher in HPVDNA/p16 positive than in HPVDNA positive/p16 negative oropharyngeal squamous cell carcinoma but does not differ significantly between various subsites or correlate to survival
- Download full text (pdf) of Human papillomavirus (HPV) load is higher in HPVDNA/p16 positive than in HPVDNA positive/p16 negative oropharyngeal squamous cell carcinoma but does not differ significantly between various subsites or correlate to survival
Systemic inflammation and prognostic markers in patients with head and neck cancer
2024
Immuno-surveillance and protection of the human cochlea
Part of Frontiers in Neurology, 2024
Part of PLOS ONE, 2024
Part of iScience, 2024
Part of BMC Cancer, 2024
- DOI for The effect of internet-administered support (carer eSupport) on preparedness for caregiving in informal caregivers of patients with head and neck cancer compared with support as usual: a study protocol for a randomized controlled trial
- Download full text (pdf) of The effect of internet-administered support (carer eSupport) on preparedness for caregiving in informal caregivers of patients with head and neck cancer compared with support as usual: a study protocol for a randomized controlled trial
Fall-related injury among patients with vestibular schwannoma
Part of PLOS ONE, 2024
Part of Digital Health and Informatics Innovations for Sustainable Health Care Systems, p. 751-755, 2024
- DOI for A Qualitative Study with Informal Caregivers and Healthcare Professionals for Individuals with Head and Neck Cancer on the Usage of AI Chatbots
- Download full text (pdf) of A Qualitative Study with Informal Caregivers and Healthcare Professionals for Individuals with Head and Neck Cancer on the Usage of AI Chatbots
Part of Scientific Reports, 2024
- DOI for Hearing loss and its association with the proteome of perilymph, cerebrospinal fluid, and tumor tissue in patients with vestibular schwannoma
- Download full text (pdf) of Hearing loss and its association with the proteome of perilymph, cerebrospinal fluid, and tumor tissue in patients with vestibular schwannoma
Accuracy of p16 IHC in Classifying HPV-Driven OPSCC in Different Populations
Part of Cancers, 2023
Part of International Journal of Molecular Sciences, 2023
- DOI for Loco-Regional Control and Sustained Difference in Serum Immune Protein Expression in Patients Treated for p16-Positive and p16-Negative Head and Neck Squamous Cell Carcinoma
- Download full text (pdf) of Loco-Regional Control and Sustained Difference in Serum Immune Protein Expression in Patients Treated for p16-Positive and p16-Negative Head and Neck Squamous Cell Carcinoma
Do Patients Aged 85 Years and above Benefit from Their Cochlear Implants?
Part of Audiology Research, p. 96-106, 2023
Part of Frontiers in Cell and Developmental Biology, 2023
Part of The Lancet Oncology, p. 239-251, 2023
- DOI for Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
- Download full text (pdf) of Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
Factors that affect quality of life for older people with head and neck cancer: A systematic review
Part of European Journal of Oncology Nursing, 2023
Part of Scientific Reports, 2023
Intrasellar Pressure is Related to Endocrine Disturbances in Patients with Pituitary Tumors
Part of World Neurosurgery, 2023
Part of Journal of Clinical Sleep Medicine (JCSM), p. 573-579, 2023
Part of Oral Oncology, 2023
Part of JAMA Otolaryngology - Head and Neck Surgery, p. 390-396, 2023
Regulatory B cells producing IL-10 are increased in human tumor draining lymph nodes
Part of International Journal of Cancer, p. 854-866, 2023
Part of Scandinavian Journal of Medicine and Science in Sports, p. 1509-1518, 2023
Part of European Journal of Oncology Nursing, 2023
- DOI for Perceptions of life and experiences of health care support among individuals one year after head and neck cancer treatment-An interview study
- Download full text (pdf) of Perceptions of life and experiences of health care support among individuals one year after head and neck cancer treatment-An interview study
Part of Nature Communications, 2023
Part of Austin Journal of Dentistry, p. 1174-1174, 2023
Part of Cancers, p. 4705-4705, 2023
Part of Scientific Reports, 2023
- DOI for Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer
- Download full text (pdf) of Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer
Part of Heliyon, 2023
Part of European Journal of Oncology Nursing, 2023
- DOI for Understanding the challenges and need for support of informal caregivers to individuals with head and neck cancer - A basis for developing internet-based support
- Download full text (pdf) of Understanding the challenges and need for support of informal caregivers to individuals with head and neck cancer - A basis for developing internet-based support
National Knowledge-Driven Management of Obstructive Sleep Apnea: The Swedish Approach
Part of Diagnostics, 2023
Part of Cancers, 2023
- DOI for High Levels of FGF11 Correlate with Poor Survival in Patients with Human Papillomavirus (HPV)-Positive Oropharyngeal Squamous Cell Carcinoma
- Download full text (pdf) of High Levels of FGF11 Correlate with Poor Survival in Patients with Human Papillomavirus (HPV)-Positive Oropharyngeal Squamous Cell Carcinoma
Part of International Wound Journal, p. 120-130, 2023
Part of Cancer Medicine, p. 12524-12534, 2023
The impact of waiting time on hearing outcome and patients' satisfaction after cholesteatoma surgery
Part of Acta Oto-Laryngologica, p. 662-668, 2023
Part of Oral surgery, oral medicine, oral pathology and oral radiology, p. 691-702, 2023
Part of Clinical Otolaryngology, p. 895-901, 2023
Part of JMIR Cancer, 2023
- DOI for Positive Design Framework for Carer-eSupport: A Qualitative Study to Support Informal Caregivers of Patients with Head and Neck Cancer in Sweden
- Download full text (pdf) of Positive Design Framework for Carer-eSupport: A Qualitative Study to Support Informal Caregivers of Patients with Head and Neck Cancer in Sweden
Auditory brainstem implant pitch discrimination and auditory outcome
Part of ACTA OTO-LARYNGOLOGICA CASE REPORTS, p. 39-43, 2022
Part of Cancers, 2022
- DOI for Longitudinal Changes in the Fatty Acid Profile in Patients with Head and Neck Cancer: Associations with Treatment and Inflammatory Response
- Download full text (pdf) of Longitudinal Changes in the Fatty Acid Profile in Patients with Head and Neck Cancer: Associations with Treatment and Inflammatory Response
Part of Acta Oncologica, p. 433-440, 2022
- DOI for Base of tongue squamous cell carcinomas, outcome depending on treatment strategy and p16 status. A population-based study from the Swedish Head and Neck Cancer Register
- Download full text (pdf) of Base of tongue squamous cell carcinomas, outcome depending on treatment strategy and p16 status. A population-based study from the Swedish Head and Neck Cancer Register
Part of Frontiers in Molecular Neuroscience, 2022
- DOI for GJB2 and GJB6 gene transcripts in the human cochlea: A study using RNAscope, confocal, and super-resolution structured illumination microscopy
- Download full text (pdf) of GJB2 and GJB6 gene transcripts in the human cochlea: A study using RNAscope, confocal, and super-resolution structured illumination microscopy
Pediatric Obstructive Sleep Apnea: Evaluation of surgical treatments and immunological aspects
2022
Part of Cancers, 2022
Unlocking the human inner ear for therapeutic intervention
Part of Scientific Reports, 2022