Anestesiologi och intensivvård

Foto: Mikael Wallerstedt

Inom forskningsområdet undersöks bland annat hur cirkulation, andning och nervsystem påverkas och kan upprätthållas efter trauma.

Forskargruppen undersöker även skademekanismer som orsakar mer omfattande ryggmärgsskador än vad det ursprungliga traumat indikerar undersöks också, liksom nybildning av glutamin vid kroppsskada och prognosmodeller för långtidsöverlevnad. Forskningen inom området anknyter till det kliniska arbetsfältet.

Forskning

Hjärtstopp-neuroprotektion
Sepsis
Forskningsprojekt inom thoraxanestesi och thoraxintensivvård
Lungfunktion
Barnanestesi och perioperativ medicin
Sedering med dexmedetetidine och remifentanil vid radiofrekvens abladering av njurcancer
AKI-gruppen: Anesthesia, Kidney and Intensive Care

Gruppmedlemmar

Forskningsledare: Sten Rubertsson

Gruppmedlemmar: Akram Abawi, Björn Ahlström, Anders Albåge, Mustafa Ali, Jimmy Almström, Hanna Andersson, Erebouni Arakelian, Kai Arnell, Anna Aronsson, Henrik Arthursson, Sana Asif, Sylvia Augustini, Anna Bandert, Lovisa Bark, Annelie Barrueta, Reka Bencze, Elisabeth Berghäll, Kristin Jóna Bjarnadóttir, Ivan Blokhin, Hans Blomberg, Erik Bruno, Sara Bûlow, Bram Burger, Lennart Christiansson, Jan Colldén, Lucian Covaciu, Sebastian de Brun, Konstantin Dirscherl, Arash Emami, Henrik Engquist, Joakim Engström, Mats Eriksson, Mikael Eriksson, Stephan Filipowski, Diddi Fors, Carley Fowler, Stephanie Franzén, Filip Fredén, Jennifer Fridman, Robert Frithiof, Peter Frykholm, Sarah Galien, Rolf Gedeborg, Anna Gradin, Peter Halvorsen, Katja Hanslin, Solveig Helgadottir, Edit Herczeghne, Anders Holmström, Bernhard Holzgraefe, Johan Hylander, Eva-Britt Hysing, Mikael Janiec, Lars Janson, Odin Joensen, Jakob Johansson, Lina Jonikaite, Torbjörn Karlsson, Rafael Kawati, Daniela Kietzmann, Anna Klaucane, Ann Kvarnström, Rickard Lagedal, Aleksandra Larina, Ing-Marie Larsson, Anders Larsson, Alexander Larsson, Ulrica Lennborn, Fredrik Lennmyr, Michael Lichtwarck-Aschoff, Chun-Yu Lin, Erik Lindgren, Miklós Lipcsey, Patrik Lundström, Tomas Luther, Daniel Löfving, Michael Marks-Hultström, Francisco Martinez, Ali-Reza Modiri, Eyla Mohlin, Maria Molnar, Rasmus Mossberg, Johan Mälberg, Sandra Nihlén, Manja Nilsson, Silvia Nyholm, Erik Näslund, David Ohlen, Alexander Otterbeck, Niccolo Pedrotti, Gaetano Perchiazzi, Emma Pontén, Bahareh Razmand, Thomas Renlund, Jacob Rosén, Christian Rylander, Paul Saretok, Petter Schiller, Eva Schmidtke, Egidijus Semenas, Magnus von Seth, Aruna Sharma, Hari Shanker Sharma, Oscar Simonson, David Smekal, Anna-Karin Smekal, Mark Solomon Mlamba, Karl Stattin, Fredrik Stiger, Kalle Stoorhöök, Gunnar Strandberg, Pernilla Sundqvist, Robert Sütterlin, Ewa Söderberg, Elin Söderman, Micael Taavo, Hanna Tegnér, Jyrki Tenhunen, Emma Thoren, Martin Tovedal, Thomas Tovedal, Ewa Wallin, Johann Valtysson, Jaap van der Heijden, Wojciech Weigl, Anna Welander, Joanna Wessbergh, Arne Wessén, Hannes Widing, Lars Wiklund, Frenne Wåhlin, Björn Zarén, Henrik Zetterström, Frank Zoerner, Emma Ågren, Sara Åkerman

Publikationer

10th Anniversary of Biomedicines—Biomarkers in Pain

Eriksson, Mats; Larsson, Anders

MDPI, 2023
- DOI för 10th Anniversary of Biomedicines—Biomarkers in Pain
- Ladda ner fulltext (pdf) av 10th Anniversary of Biomedicines—Biomarkers in Pain
10th Clinical Trials on Alzheimer's Disease (CTAD), Boston MA, USA, November 1-4, 2017

Sharma, Hari Shanker; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 1134-1137, 2017
- DOI för 10th Clinical Trials on Alzheimer's Disease (CTAD), Boston MA, USA, November 1-4, 2017
11th International Conference on Neuroprotective Agents, Wendake, Quebec City, Quebec, Canada, Sept 30-Oct 3, 2012

Sharma, Hari Shanker; Sharma, Aruna; Skaper, Stephen

Ingår i CNS & Neurological Disorders, s. 951-952, 2012
12th International Congress on Neuroprotective Agents (ICNA), Charlottesville, VA, USA September 28, 2014-Ocobert 01, 2014

Sharma, Hari Shanker; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 1308-1309, 2014
- DOI för 12th International Congress on Neuroprotective Agents (ICNA), Charlottesville, VA, USA September 28, 2014-Ocobert 01, 2014
14th International Congress on Amino Acids, Peptides and Proteins, Vienna, Austria, August 3-7, 2015

Sharma, Hari S.; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 644-645, 2016
- DOI för 14th International Congress on Amino Acids, Peptides and Proteins, Vienna, Austria, August 3-7, 2015
181st Annual Meeting of the American Association for the Advancement of Science (AAAS), San Jose Convention Center, San Jose, CA, USA February 12-16, 2015

Sharma, Hari Shanker; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 434-436, 2015
183rd American Association for the Advancement of Science Annual Meeting, Boston MA, USA Feb 16-20, 2017 "Serving Society through Science Policy"

Sharma, Hari S.; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 965-968, 2017
- DOI för 183rd American Association for the Advancement of Science Annual Meeting, Boston MA, USA Feb 16-20, 2017 "Serving Society through Science Policy"
184th American Association for the Advancement of Science Annual Meeting, Austin TX, USA Feb. 15-19, 2018

Sharma, Hari Shanker; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 240-242, 2018
- DOI för 184th American Association for the Advancement of Science Annual Meeting, Austin TX, USA Feb. 15-19, 2018
2018 Yearbook of Neurorestoratology

Huang, Hongyun; Sharma, Hari Shanker; Chen, Lin; Saberi, Hooshang et al.

Ingår i JOURNAL OF NEURORESTORATOLOGY, s. 8-17, 2019
- DOI för 2018 Yearbook of Neurorestoratology
24-Hour ambulatory blood pressure associates inversely with prostaglandin F-2 alpha, interleukin-6 and F-2-isoprostane formation in a Swedish population of older men

Helmersson-Karlqvist, Johanna; Björklund-Bodegard, Kristina; Larsson, Anders; Basu, Samar

Ingår i International Journal of Clinical and Experimental Medicine, s. 145-153, 2012
3-Bromofascaplysin is a prospective chemical compound for developing new chemotherapy agents in glioblastoma treatment

Lyakhova, Irina; Piatkova, Mariia; Khotimchenko, Yuri; Zhidkov, Maxim et al.

Ingår i Novel therapeutic advances in glioblastoma, s. 325-343, Elsevier BV, 2020
- DOI för 3-Bromofascaplysin is a prospective chemical compound for developing new chemotherapy agents in glioblastoma treatment
5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology

Sharma, Aruna; Castellani, Rudy J.; Smith, Mark A.; Muresanu, Dafin Fior et al.

Ingår i New Therapeutic Strategies for Brain Edema and Cell Injury, s. 1-44, Elsevier, 2019
- DOI för 5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology
5th Annual Global College of Neuroprotection and Neuroregeneration

Sharma, Hari Shanker

Ingår i Expert review of neurotherapeutics, s. 881-7, 2008
- DOI för 5th Annual Global College of Neuroprotection and Neuroregeneration
5th International Conference on Nanotek & Expo, Nov 16-18, 2015, San Antonio TX, USA

Sharma, Hari Shanker; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 265-266, 2016
- DOI för 5th International Conference on Nanotek & Expo, Nov 16-18, 2015, San Antonio TX, USA
6th Clinical Trials on Alzheimer's Disease (CTAD) Conference, Nov 14-16, 2013, The Westin San Diego Gaslamp Quarter Hotel, San Diego, CA, USA

Sharma, Hari Shanker; Sharma, Aruna; Skaper, Stephen D.

Ingår i CNS & Neurological Disorders, s. 187-190, 2014
6th Global College of Neuroprotection and Neuroregeneration, annual meeting

Sharma, Hari Shanker; Sharma, Aruna

Ingår i Expert review of neurotherapeutics, s. 941-947, 2009
- DOI för 6th Global College of Neuroprotection and Neuroregeneration, annual meeting
7th Clinical Trials on Alzheimer's Disease Annual Conference, Philadelphia, PA, USA Nov 20-22, 2014

Sharma, Hari Shanker; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 7-10, 2015
- DOI för 7th Clinical Trials on Alzheimer's Disease Annual Conference, Philadelphia, PA, USA Nov 20-22, 2014
8th Clinical Trials on Alzheimer Disease (CTAD), Barcelona, Spain November 5-7, 2015

Sharma, Hari S.; Skaper, Stephen D.; Sharma, Aruna

Ingår i CNS & Neurological Disorders, s. 375-377, 2016
- DOI för 8th Clinical Trials on Alzheimer Disease (CTAD), Barcelona, Spain November 5-7, 2015
A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)

Philippot, Gaetan; Hallgren, Stefan; Gordh, Torsten; Fredriksson, Anders et al.

Ingår i Toxicological Sciences, s. 203-212, 2018
- DOI för A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)
- Ladda ner fulltext (pdf) av A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)
A clinical study of high-dose urokinase for the treatment of the patients with hypertension induced ventricular hemorrhage

He, Chao; Yang, Gang; Zhao, Ming; Wu, Qilin et al.

Ingår i Brain protection strategies and nanomedicine, s. 349-355, Elsevier BV, 2021
- DOI för A clinical study of high-dose urokinase for the treatment of the patients with hypertension induced ventricular hemorrhage
A combination of tumor necrosis factor-α and neuronal nitric oxide synthase antibodies applied topically over the traumatized spinal cord enhances neuroprotection and functional recovery in the rat

Sharma, Hari Shanker

Ingår i Annals of the New York Academy of Sciences, s. 175-185, 2010
- DOI för A combination of tumor necrosis factor-α and neuronal nitric oxide synthase antibodies applied topically over the traumatized spinal cord enhances neuroprotection and functional recovery in the rat
A Comparison between Endostatin and Conventional Biomarkers on 30-Day Mortality and Renal Replacement Therapy in Unselected Intensive Care Patients

Ruge, Toralph; Larsson, Anders; Lipcsey, Miklós; Tydén, Jonas et al.

Ingår i Biomedicines, 2021
- DOI för A Comparison between Endostatin and Conventional Biomarkers on 30-Day Mortality and Renal Replacement Therapy in Unselected Intensive Care Patients
- Ladda ner fulltext (pdf) av A Comparison between Endostatin and Conventional Biomarkers on 30-Day Mortality and Renal Replacement Therapy in Unselected Intensive Care Patients
A comparison between PEEP titration methods in a porcine ARDS model

Pino, Fabio; Ball, Lorenzo; Scaramuzzo, Gaetano; Pinol Ribas, Miquel et al.

Ingår i Acta Anaesthesiologica Scandinavica, s. 1024-1025, 2017
A comparison of auditory evoked potentials and spectral EEG in the ability to detect marked sevoflurane concentration alterations and clinical events

Enlund, Mats; Jansson, Per

Ingår i Upsala Journal of Medical Sciences, Supplement, s. 221-229, 2007
- DOI för A comparison of auditory evoked potentials and spectral EEG in the ability to detect marked sevoflurane concentration alterations and clinical events
A comparison of impact of comorbidities and demographics on 60-day mortality in ICU patients with COVID-19, sepsis and acute respiratory distress syndrome

Ahlström, Björn; Frithiof, Robert; Larsson, Ing-Marie; Strandberg, Gunnar et al.

Ingår i Scientific Reports, 2022
- DOI för A comparison of impact of comorbidities and demographics on 60-day mortality in ICU patients with COVID-19, sepsis and acute respiratory distress syndrome
- Ladda ner fulltext (pdf) av A comparison of impact of comorbidities and demographics on 60-day mortality in ICU patients with COVID-19, sepsis and acute respiratory distress syndrome
A comparison of three doses of sufentanil in combination withbupivacaine-adrenaline in continuous epidural analgesia during labour.

Eriksson, SL; Frykholm, Peter; Stenlund, PM; Olofsson, C

Ingår i Acta Anaesthesiol. Scand., s. 919, 2000
A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention

Jung, Christian; Wernly, Bernhard; Muessig, Johanna M.; Kelm, Malte et al.

Ingår i Journal of critical care, s. 141-148, 2019
- DOI för A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention
A drug comorbidity index to predict mortality in men with castration resistant prostate cancer

Fallara, Giuseppe; Gedeborg, Rolf; Bill-Axelson, Anna; Garmo, Hans et al.

Ingår i PLOS ONE, 2021
- DOI för A drug comorbidity index to predict mortality in men with castration resistant prostate cancer
- Ladda ner fulltext (pdf) av A drug comorbidity index to predict mortality in men with castration resistant prostate cancer
A European survey of nosocomial infection control and hospital-acquired pneumonia prevention practices

Ricard, Jean-Damien; Conti, Giorgio; Boucherie, Maud; Hormann, Christoph et al.

Ingår i Journal of Infection, s. 285-291, 2012
- DOI för A European survey of nosocomial infection control and hospital-acquired pneumonia prevention practices
A first update on mapping the human genetic architecture of COVID-19

Pathak, Gita A.; Frithiof, Robert; Hultström, Michael; Lipcsey, Miklós et al.

Ingår i Nature, 2022
- DOI för A first update on mapping the human genetic architecture of COVID-19
- Ladda ner fulltext (pdf) av A first update on mapping the human genetic architecture of COVID-19
A global systematic analysis of the occurrence, severity, and recovery pattern of long COVID in 2020 and 2021

Wulf Hanson, Sarah; Abbafati, Cristiana; Aerts, Joachim G; Al-Aly, Ziyad et al.

2022
- DOI för A global systematic analysis of the occurrence, severity, and recovery pattern of long COVID in 2020 and 2021
A history of nordic anesthesia

Stromskag, Kjell Erik; Brock-Utne, Johan G.; Eklund, Jan; Holmdahl, Martin H:son

Ingår i The Wondrous Story of Anesthesia, s. 417-428, Springer-Verlag New York, 2014
- DOI för A history of nordic anesthesia
A journey to a new stable state-further development of the postoperative recovery concept from day surgical perspective: a qualitative study

Nilsson, Ulrica; Jaensson, Maria; Hugelius, Karin; Arakelian, Erebouni et al.

Ingår i BMJ Open, 2020
- DOI för A journey to a new stable state-further development of the postoperative recovery concept from day surgical perspective: a qualitative study
- Ladda ner fulltext (pdf) av A journey to a new stable state-further development of the postoperative recovery concept from day surgical perspective: a qualitative study
A metabolic threshold of irreversible ischemia demonstrated by PET in amiddle cerebral artery occlusion-reperfusion primate model.

Frykholm, Peter; Andersson, JL; Valtysson, Johann; Silander, HC et al.

Ingår i Acta Neurol Scand, s. 18, 2000
A model-based source separation algorithm for lung perfusion imaging using electrical impedance tomography

Hentze, Benjamin; Muders, Thomas; Antink, Christoph Hoog; Putensen, Christian et al.

Ingår i Physiological Measurement, 2021
- DOI för A model-based source separation algorithm for lung perfusion imaging using electrical impedance tomography
- Ladda ner fulltext (pdf) av A model-based source separation algorithm for lung perfusion imaging using electrical impedance tomography
A modified breathing pattern improves the performance of a continuous capnodynamic method for estimation of effective pulmonary blood flow

Hällsjö Sander, Caroline; Sigmundsson, Thorir; Hallbäck, Magnus; Suarez-Sipmann, Fernando et al.

Ingår i Journal of clinical monitoring and computing, s. 717-725, 2017
- DOI för A modified breathing pattern improves the performance of a continuous capnodynamic method for estimation of effective pulmonary blood flow
A modified Glenn shunt improves haemodynamics in acute right ventricular failure in an experimental model

Vikholm, Per; Schiller, Petter; Johansson, Jakob; Hellgren, Laila

Ingår i European Journal of Cardio-Thoracic Surgery, s. 612-618, 2013
- DOI för A modified Glenn shunt improves haemodynamics in acute right ventricular failure in an experimental model
A Multicenter Randomized Trial Comparing a Mechanical CPR Algorithm Using LUCAS Versus Manual CPR in Out-of-Hospital Cardiac Arrest Patients-Per Protocol Analysis of the LINC Study

Rubertsson, Sten; Lindgren, Erik; Östlund, Ollie; Herlitz, Johan et al.

Ingår i Circulation, s. 2719-2719, 2013
A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind, Anne-Li; Yu, Di; Freyhult, Eva; Bodolea, Constantin et al.

Ingår i PLOS ONE, 2016
- DOI för A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
- Ladda ner fulltext (pdf) av A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
A nationwide cohort study on the association between intensive care treatments and mental distress linked psychiatric disorders

Mossberg, Rasmus; Ahlström, Björn; Lipcsey, Miklós

Ingår i Scientific Reports, 2024
- DOI för A nationwide cohort study on the association between intensive care treatments and mental distress linked psychiatric disorders
- Ladda ner fulltext (pdf) av A nationwide cohort study on the association between intensive care treatments and mental distress linked psychiatric disorders
A nationwide postal questionnaire survey: the presence of airway guidelines in anaesthesia department in Sweden

Knudsen, Kati; Pöder, Ulrika; Högman, Marieann; Larsson, Anders et al.

Ingår i BMC Anesthesiology, s. 25, 2014
- DOI för A nationwide postal questionnaire survey: the presence of airway guidelines in anaesthesia department in Sweden
- Ladda ner fulltext (pdf) av A nationwide postal questionnaire survey: the presence of airway guidelines in anaesthesia department in Sweden
A nationwide study of the long-term prevalence of dementia and its risk factors in the Swedish intensive care cohort

Ahlström, Björn; Larsson, Ing-Marie; Strandberg, Gunnar; Lipcsey, Miklós

Ingår i Critical Care, 2020
- DOI för A nationwide study of the long-term prevalence of dementia and its risk factors in the Swedish intensive care cohort
- Ladda ner fulltext (pdf) av A nationwide study of the long-term prevalence of dementia and its risk factors in the Swedish intensive care cohort
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

Zhou, Sirui; Butler-Laporte, Guillaume; Nakanishi, Tomoko; Morrison, David R. et al.

Ingår i Nature Medicine, s. 659-667, 2021
- DOI för A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity
A networking and publishing tool for pain researchers and pain clinicians in the Nordic countries

Breivik, Harald; Gordh, Torsten; Kalso, Eija; Jensen, Troels S. et al.

Ingår i Scandinavian Journal of Pain, s. 1-2, 2010
- DOI för A networking and publishing tool for pain researchers and pain clinicians in the Nordic countries
A New Antioxidant Compound H-290/51 Attenuates Nanoparticle Induced Neurotoxicity and Enhances Neurorepair in Hyperthermia

Sharma, Hari Shanker; Sharma, Aruna; Hussain, Saber; Schlager, John et al.

Ingår i Brain Edema XIV, s. 351-357, 2010
- DOI för A New Antioxidant Compound H-290/51 Attenuates Nanoparticle Induced Neurotoxicity and Enhances Neurorepair in Hyperthermia
A new device för administration of nasal CPAP in the newborn

Moa, Gunnar; Nilsson, Kjell; Zetterström, Henrik; Jonsson, Lars O

Ingår i Critical Care Medicine, s. 1238-1242, 1988
A new device to reduce inhalational agent expenditure

Enlund, Mats; Lambert, H; Wiklund, Lars

Ingår i Anest Analg, s. 201, 2000
A new device to reduce the consumption of a halogenated anaesthetic agent.

Enlund, Mats; Wiklund, Lars; Lambert, H

Ingår i Anaesthesia, s. 429, 2001
A new method of intrathecal PO2, PCO2, and pH measurements for continuous monitoring of spinal cord ischemia during thoracic aortic clamping in pigs

Christiansson, Lennart; Hellberg, Anders; Koga, Itaru; Thelin, Stefan et al.

Ingår i Surgery, s. 571-576, 2000
- DOI för A new method of intrathecal PO2, PCO2, and pH measurements for continuous monitoring of spinal cord ischemia during thoracic aortic clamping in pigs
A new nomogram facilitating adequate haemodilution

Zetterström, Henrik; Wiklund, Lars

Ingår i Acta Anaesthesiologica Scandinavica, s. 300-304, 1986