Funktionell farmakologi och neurovetenskap

Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank

Xiao, Shanshan; Ebner, Natalie C.; Dang, Junhua; Rukh, Gull et al.

Ingår i Cortex, s. 211-219, 2025

• DOI för Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
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A Haplotype GWAS in Syndromic Familial Colorectal Cancer

Vermani, Litika; Winnberg, Johanna Samola; Liu, Wen; Soller, Veronika et al.

Ingår i International Journal of Molecular Sciences, 2025

• DOI för A Haplotype GWAS in Syndromic Familial Colorectal Cancer
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Critical Insights Into LEAP2 Biology and Physiological Functions: Potential Roles Beyond Ghrelin Antagonism

Perello, Mario

Ingår i Endocrinology, 2025

• DOI för Critical Insights Into LEAP2 Biology and Physiological Functions: Potential Roles Beyond Ghrelin Antagonism

Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism

Mohammad, Salahuddin; Bussu, Giorgia; Rukh, Gull; Schiöth, Helgi B. et al.

Ingår i Cephalalgia, s. 1-12, 2025

• DOI för Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review

Karimi, Isaac; Ghowsi, Mahnaz; Mohammed, Layth Jasim; Haidari, Zohreh et al.

Ingår i Polymers, 2025

• DOI för Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review
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GPCR drug discovery: new agents, targets and indications

Lorente, Javier Sánchez; Sokolov, Aleksandr V.; Ferguson, Gavin; Schiöth, Helgi et al.

Ingår i Nature reviews. Drug discovery, 2025

• DOI för GPCR drug discovery: new agents, targets and indications

Identification of candidate biomarkers in neurological and psychiatric health

Lafta, Muataz

2025

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Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments

Kosheleva, Liudmila; Koshelev, Daniil; Lagunas-Rangel, Francisco Alejandro; Levit, Shmuel et al.

Ingår i Pharmacological Reviews, 2025

• DOI för Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments
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Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations

Vekhova, Ksenia A.; Namiot, Eugenia D.; Jonsson, Jörgen; Schiöth, Helgi

Ingår i Clinical Pharmacology and Therapeutics, s. 374-386, 2025

• DOI för Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations
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Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology

Karimi, Isaac; Mohammad, Layth Jasim; Suvitha, A.; Haidari, Zohreh et al.

Ingår i Frontiers in Toxicology, 2025

• DOI för Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology
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New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI

Wang, Hu; Li, Yanru; Chen, Shuai; Yan, Jie et al.

Ingår i Sensors and actuators. B, Chemical, 2025

• DOI för New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI
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Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

Sun, Chenggong; Li, Xiao; Teng, Qiuli; Liu, Xihan et al.

Ingår i Theranostics, s. 3055-3075, 2025

• DOI för Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

The relationship between national identity and public health support needs to be reconsidered

Dang, Junhua; Du, Hongfei; Ma, Zhihao; Xu, Lili et al.

Ingår i Frontiers in Psychology, 2025

• DOI för The relationship between national identity and public health support needs to be reconsidered
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Exploring the effects of long-term physical exercise on persistent and inhibitory self-control: quasi-experimental research

Cheng, Linjing; Qin, Huahui; Yang, Yin; Dang, Junhua

Ingår i Frontiers in Sports and Active Living, 2025

• DOI för Exploring the effects of long-term physical exercise on persistent and inhibitory self-control: quasi-experimental research
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Giardia fibrillarin: a bioinformatics exploration of sequence and structure

Lagunas-Rangel, Francisco Alejandro

Ingår i Journal of Applied Genetics, s. 241-248, 2025

• DOI för Giardia fibrillarin: a bioinformatics exploration of sequence and structure
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Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Peng, Lu; Sun, Rui; Hao, Tingting; Mu, Yulong et al.

Ingår i Molecular Medicine Reports, 2025

• DOI för Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer
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Cholesterol effects on the tumor immune microenvironment: from fundamental concepts to mechanisms and implications

Lagunas-Rangel, Francisco Alejandro

Ingår i Frontiers in Oncology, 2025

• DOI för Cholesterol effects on the tumor immune microenvironment: from fundamental concepts to mechanisms and implications
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Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties

Muslim, Wisam Taher; Mohammad, Layth Jasim; Naji, Munaf M.; Karimi, Isaac et al.

Ingår i Frontiers in Pharmacology, 2025

• DOI för Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
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Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Lafta, Muataz S.; Mwinyi, Jessica; Affatato, Oreste; Rukh, Gull et al.

Ingår i Frontiers in Neuroscience, 2024

• DOI för Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi

Ingår i Polymers, 2024

• DOI för Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery
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Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Ingår i Scientific Reports, 2024

• DOI för Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)

Brooks, Samantha; Dahl, K.; Dudley-Jones, R.; Schiöth, Helgi

Ingår i Neuroscience and Biobehavioral Reviews, 2024

• DOI för A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
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Giardia telomeres and telomerase

Lagunas-Rangel, Francisco Alejandro

Ingår i Parasitology Research, 2024

• DOI för Giardia telomeres and telomerase
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Learning with AI Language Models: Guidelines for the Development and Scoring of Medical Questions for Higher Education

Moulin, Thiago C.

Ingår i Journal of medical systems, 2024

• DOI för Learning with AI Language Models: Guidelines for the Development and Scoring of Medical Questions for Higher Education

Beating of hammers

Affatato, Oreste

2024

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STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Liu, Jiale; Liu, Chenmian; Ma, Yana; Pan, Xiyu et al.

Ingår i Cancer Letters, 2024

• DOI för STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
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The Pattern of GH Action in the Mouse Brain

Menezes, Filipe; Wasinski, Frederick; de Souza, Gabriel O.; Nunes, Amanda P. et al.

Ingår i Endocrinology, 2024

• DOI för The Pattern of GH Action in the Mouse Brain

Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

Gentreau, Melissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura et al.

Ingår i The journals of gerontology. Series A, Biological sciences and medical sciences, 2024

• DOI för Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers

Smith-Byrne, Karl; Hedman, Åsa; Dimitriou, Marios; Desai, Trishna et al.

Ingår i Nature Communications, 2024

• DOI för Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
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Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Desai, Trishna A.; Hedman, Asa K.; Dimitriou, Marios; Koprulu, Mine et al.

Ingår i EBioMedicine, 2024

• DOI för Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Mohammad, Salahuddin; Gentreau, Mélissa; Dubol, Manon; Rukh, Gull et al.

Ingår i Molecular Autism, 2024

• DOI för Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
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Deciphering Adult Autism: Exploring Polygenic Risk, Brain Structure, Well-being, Migraine, and Mental Health Disorders

Mohammad, Salahuddin

2024

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Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer

Wu, Huan; Sun, Chenggong; Cao, Wenyu; Teng, Qiuli et al.

Ingår i Cancer Letters, 2024

• DOI för Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer
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Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales

Bondarev, Andrey D.; Jonsson, Jörgen; Chubarev, Vladimir N.; V. Tarasov, Vadim et al.

Ingår i Pharmacological Research, 2024

• DOI för Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales
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The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Rafeletou, Alexandra; Niemi, Jenni; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Ingår i Science of the Total Environment, 2024

• DOI för The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Biomarkers for depression: genetic, epigenetic, and expression evidence

Sokolov, Aleksandr V.

2024

• Ladda ner fulltext (pdf) av Biomarkers for depression: genetic, epigenetic, and expression evidence

Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons

Hosseini, Kimia; Cediel Ulloa, Andrea; Al-Sabri, Mohamed H.; Forsby, Anna et al.

Ingår i Pharmaceuticals, 2024

• DOI för Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons
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Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Sokolov, Aleksandr V.; Schiöth, Helgi

Ingår i Translational Psychiatry, 2024

• DOI för Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
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Aging insights from heterochronic parabiosis models

Lagunas-Rangel, Francisco Alejandro

Ingår i NPJ AGING, 2024

• DOI för Aging insights from heterochronic parabiosis models
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Role of circular RNAs in DNA repair

Lagunas-Rangel, Francisco Alejandro

Ingår i RNA Biology, s. 149-161, 2024

• DOI för Role of circular RNAs in DNA repair
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Exploration of Giardia small nucleolar RNAs (snoRNAs) and their possible microRNA derivatives

Lagunas-Rangel, Francisco Alejandro

Ingår i Parasitology, s. 539-545, 2024

• DOI för Exploration of Giardia small nucleolar RNAs (snoRNAs) and their possible microRNA derivatives
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Advances in development of biomarkers for brain damage and ischemia

Karimova, Diana; Rostami, Elham; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i Molecular Biology Reports, 2024

• DOI för Advances in development of biomarkers for brain damage and ischemia
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Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells.

Liao, Sifang; Sun, Chengxi; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Ingår i Science of the Total Environment, s. 177472, 2024

• DOI för Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells.

Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes

Gentreau, Mélissa; Miguet, Maud; Affatato, Oreste; Rukh, Gull et al.

Ingår i Brain Communications, 2024

• DOI för Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
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Effects of psychedelics on neurogenesis and broader neuroplasticity: a systematic review

Lima da Cruz, Rafael V.; Leão, Richardson N.; Moulin, Thiago C.

Ingår i Molecular Medicine, 2024

• DOI för Effects of psychedelics on neurogenesis and broader neuroplasticity: a systematic review
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Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects

Vermani, Litika; Barnekow, Elin; Liu, Wen; Wendt, Camilla et al.

Ingår i Genes, 2024

• DOI för Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects
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Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Manzke Glänzel, Nícolas; Teixeira da Rosa-Junior, Nevton; Signori, Marian F.; de Andrade Silveira, Josyane et al.

Ingår i Metabolic brain disease, 2024

• DOI för Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Aguggia, Julieta; Fernandez, Gimena; Cassano, Daniela; Mustafá, Emilio R. et al.

Ingår i Endocrinology, 2024

• DOI för Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain

Saenz, Camila; Fernandez, Gimena; Llovera, Ramiro; Tolosa, María J. et al.

Ingår i Brain Structure and Function, 2024

• DOI för Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain
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Diagnosis and Treatment of Bronchopulmonary Lophomoniasis in a Patient with Persistent Granuloma: A Case Report

Mier-Briseno, Antonio; Ramirez-Alanis, Eloisa; Benavides-Huerto, Miguel Armando; Lagunas-Rangel, Francisco Alejandro

Ingår i REPORTS, 2024

• DOI för Diagnosis and Treatment of Bronchopulmonary Lophomoniasis in a Patient with Persistent Granuloma: A Case Report
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