Dermatologi och venereologi
Inom forskargruppen inom dermatologi och venereologi bedrivs forskning kring inflammatoriska och ärftliga hudsjukdomar, hudcancer, samt hudens barriärfunktion.
Beskrivning av vår forskning
Forskningen som bedrivs omfattar experimentell och translationell laboratoriebaserad forskning samt klinisk forskning. Det övergripande syftet är att förstå molekylära mekanismer som driver inflammatoriska och maligna hudsjukdomar för att kunna utveckla nya, innovativa behandlingsstrategier, samt att med hjälp av forskningsregister och biobank kunna följa upp patienterna, kartlägga effekten av olika behandlingar, sambandet med andra sjukdomar och patienternas upplevelse av sjukdomen.
Forskargruppen leds av professor Enikö Sonkoly och involverar både grundforskare och kliniskt aktiva forskare.

Medlemmarna i forskargruppen.
Gruppmedlemmar
Publikationer
Ingår i Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025
- DOI för Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
- Ladda ner fulltext (pdf) av Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
Ingår i Aesthetic surgery journal, s. 1218-1226, 2024
- DOI för A Prospective, Randomized, Double-Blind, Split-Face, Comparative Study to Evaluate the Efficacy and Safety of DKL23 and Juvederm Volift for Correcting Moderate-to-Severe Nasolabial Folds
- Ladda ner fulltext (pdf) av A Prospective, Randomized, Double-Blind, Split-Face, Comparative Study to Evaluate the Efficacy and Safety of DKL23 and Juvederm Volift for Correcting Moderate-to-Severe Nasolabial Folds
Epidemiology of mastocytosis: a population-based study (Sweden)
Ingår i Acta Oncologica, s. 44-50, 2024
- DOI för Epidemiology of mastocytosis: a population-based study (Sweden)
- Ladda ner fulltext (pdf) av Epidemiology of mastocytosis: a population-based study (Sweden)
Ingår i Acta Dermato-Venereologica, 2024
- DOI för The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
- Ladda ner fulltext (pdf) av The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation and Ethical Challenges
Young ESDR: Engaging and Nurturing the Next-Generation Skin Research Community
Ingår i Journal of Investigative Dermatology, s. 2349-2350, 2024
Ingår i British Journal of Dermatology, s. 635-637, 2024
In memoriam professor Annamari Ranki
Ingår i Acta Dermato-Venereologica, 2024
- DOI för In memoriam professor Annamari Ranki
- Ladda ner fulltext (pdf) av In memoriam professor Annamari Ranki
Ingår i Acta Dermato-Venereologica, 2024
- DOI för Guselkumab in Patients with Scalp Psoriasis: A post hoc Analysis of the VOYAGE 2 Phase III Randomized Clinical Trial
- Ladda ner fulltext (pdf) av Guselkumab in Patients with Scalp Psoriasis: A post hoc Analysis of the VOYAGE 2 Phase III Randomized Clinical Trial
A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization
Ingår i Journal of Investigative Dermatology, s. 1667-1677, 2023
- DOI för A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization
- Ladda ner fulltext (pdf) av A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization
Ingår i Acta Dermato-Venereologica, 2023
- DOI för Establishment and Utility of SwedAD: A Nationwide Swedish Registry for Patients with Atopic Dermatitis Receiving Systemic Pharmacotherapy
- Ladda ner fulltext (pdf) av Establishment and Utility of SwedAD: A Nationwide Swedish Registry for Patients with Atopic Dermatitis Receiving Systemic Pharmacotherapy
Ingår i Cell Death Discovery, 2023
- DOI för Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts
- Ladda ner fulltext (pdf) av Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts
Ingår i British Journal of Dermatology, s. 415-426, 2023
- DOI för Long noncoding RNA plasmacytoma variant translocation 1 is overexpressed in cutaneous squamous cell carcinoma and exon 2 is critical for its oncogenicity
- Ladda ner fulltext (pdf) av Long noncoding RNA plasmacytoma variant translocation 1 is overexpressed in cutaneous squamous cell carcinoma and exon 2 is critical for its oncogenicity
Ingår i Journal of Investigative Dermatology, s. 999-1010, 2023
Keeping up appearances: Don't frown upon the effects of botulinum toxin injections in facial muscles
Ingår i Clinical Neurophysiology Practice, s. 169-173, 2023
- DOI för Keeping up appearances: Don't frown upon the effects of botulinum toxin injections in facial muscles
- Ladda ner fulltext (pdf) av Keeping up appearances: Don't frown upon the effects of botulinum toxin injections in facial muscles
Ingår i Journal of Investigative Dermatology, s. 2386-2396, 2023
- DOI för MicroRNA-23b Plays a Tumor-Suppressive Role in Cutaneous Squamous Cell Carcinoma and Targets Ras-Related Protein RRAS2
- Ladda ner fulltext (pdf) av MicroRNA-23b Plays a Tumor-Suppressive Role in Cutaneous Squamous Cell Carcinoma and Targets Ras-Related Protein RRAS2
Ingår i Arthritis Research & Therapy, 2023
- DOI för Nail psoriasis dynamics during biologic treatment and withdrawal in patients with psoriasis who may be at high risk of developing psoriatic arthritis: a post hoc analysis of the VOYAGE 2 randomized trial
- Ladda ner fulltext (pdf) av Nail psoriasis dynamics during biologic treatment and withdrawal in patients with psoriasis who may be at high risk of developing psoriatic arthritis: a post hoc analysis of the VOYAGE 2 randomized trial
Monensin induces secretory granule-mediated cell death in eosinophils
Ingår i Journal of Allergy and Clinical Immunology, 2023
- DOI för Monensin induces secretory granule-mediated cell death in eosinophils
- Ladda ner fulltext (pdf) av Monensin induces secretory granule-mediated cell death in eosinophils
Ingår i Acta Dermato-Venereologica, 2022
- DOI för Dermatology Life Quality Index as a Prognostic Tool for Predicting Need for Healthcare in Patients with Eczema: A Pilot Study
- Ladda ner fulltext (pdf) av Dermatology Life Quality Index as a Prognostic Tool for Predicting Need for Healthcare in Patients with Eczema: A Pilot Study
Ingår i Experimental dermatology, s. 1729-1740, 2022
- DOI för Mefloquine causes selective mast cell apoptosis in cutaneous mastocytosis lesions by a secretory granule-mediated pathway
- Ladda ner fulltext (pdf) av Mefloquine causes selective mast cell apoptosis in cutaneous mastocytosis lesions by a secretory granule-mediated pathway
Reversal of the disease signature in prurigo nodularis by blocking the itch cytokine
Ingår i Journal of Allergy and Clinical Immunology, s. 1213-1215, 2022
Ingår i JAMA dermatology, s. 561-561, 2022
Ingår i Journal of Allergy and Clinical Immunology, s. 718-727, 2022
- DOI för Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
- Ladda ner fulltext (pdf) av Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
Ingår i Journal of the European Academy of Dermatology and Venereology, s. 2076-2086, 2022
Scoring the Risk of Having Systemic Mastocytosis in Adult Patients with Mastocytosis in the Skin
Ingår i Journal of Allergy and Clinical Immunology, s. 1705-17120000, 2021
Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients
Ingår i Genes, 2021
- DOI för Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients
- Ladda ner fulltext (pdf) av Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients
Monensin induces selective mast cell apoptosis through a secretory granule-mediated pathway.
Ingår i Allergy. European Journal of Allergy and Clinical Immunology, 2021
- DOI för Monensin induces selective mast cell apoptosis through a secretory granule-mediated pathway.
- Ladda ner fulltext (pdf) av Monensin induces selective mast cell apoptosis through a secretory granule-mediated pathway.
Ingår i Differentiation, s. 19-27, 2021
Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA
Ingår i International Journal of Molecular Sciences, 2020
- DOI för Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA
- Ladda ner fulltext (pdf) av Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA
Ingår i American Journal of Clinical Dermatology, s. 741-748, 2020
- DOI för Botulinum Toxin Type B for Hidradenitis Suppurativa: A Randomised, Double-Blind, Placebo-Controlled Pilot Study
- Ladda ner fulltext (pdf) av Botulinum Toxin Type B for Hidradenitis Suppurativa: A Randomised, Double-Blind, Placebo-Controlled Pilot Study
Ingår i The Journal of American Academy of Dermatology, s. 1109-1116, 2020
Flodvåg av långtidssjuka covid-19-patienter väntar
Ingår i Dagens Nyheter, s. 5-5, 2020
Habitual scratching amplifies and perpetuates atopic dermatitis
Ingår i British Journal of Dermatology, s. 403-403, 2020
Pioneers in Dermatology and Venereology: an interview with Prof. Anders Vahlquist
Ingår i Journal of the European Academy of Dermatology and Venereology, s. 2691-2692, 2020
Ichthyosis: A Road Model for Skin Research
Ingår i Acta Dermato-Venereologica, s. 197-206, 2020
- DOI för Ichthyosis: A Road Model for Skin Research
- Ladda ner fulltext (pdf) av Ichthyosis: A Road Model for Skin Research
MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4
Ingår i Journal of Investigative Dermatology, s. 465-476, 2020
Postmenopausal craniofacial hyperhidrosis treated with botulinum toxin type B
Ingår i Journal of dermatology (Print), s. 874-878, 2019
Ingår i Stem Cell Research, 2019
- DOI för Induced pluripotent stem cell (iPSC) line from an epidermolysis bullosa simplex patient heterozygous for keratin 5 E475G mutation and with the Dowling Meara phenotype
- Ladda ner fulltext (pdf) av Induced pluripotent stem cell (iPSC) line from an epidermolysis bullosa simplex patient heterozygous for keratin 5 E475G mutation and with the Dowling Meara phenotype
Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 9443-9452, 2019
- DOI för Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
- Ladda ner fulltext (pdf) av Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Management of congenital ichthyoses: European guidelines of care, part two
Ingår i British Journal of Dermatology, s. 484-495, 2019
Management of congenital ichthyoses: European guidelines of care, part one
Ingår i British Journal of Dermatology, s. 272-281, 2019
Ingår i Journal de Mycologie Médicale, s. 1-6, 2019
Observational Study of Clindamycin Phosphate and Tretinoin Gel for the Treatment of Acne
Ingår i JOURNAL OF DRUGS IN DERMATOLOGY, s. 328-334, 2019
2019
Ingår i Experimental dermatology, s. 1164-1171, 2019
- DOI för Patients with congenital ichthyosis and TGM1 mutations overexpress other ARCI genes in the skin: Part of a barrier repair response?
- Ladda ner fulltext (pdf) av Patients with congenital ichthyosis and TGM1 mutations overexpress other ARCI genes in the skin: Part of a barrier repair response?
Ingår i The Journal of American Academy of Dermatology, s. 487-494, 2018
Ingår i Experimental dermatology, s. 16-17, 2018
Ingår i Scientific Reports, 2018
- DOI för Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden
- Ladda ner fulltext (pdf) av Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden
Ingår i Journal of Clinical Endocrinology and Metabolism, s. 179-186, 2018
- DOI för Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1
- Ladda ner fulltext (pdf) av Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1
Ingår i Acta Dermato-Venereologica, s. 103-107, 2018
Identification of mutations in SDR9C7 in six families with autosomal recessive congenital ichthyosis
Ingår i British Journal of Dermatology, 2018