Mikael Sellin
Professor Docent vid Institutionen för medicinsk biokemi och mikrobiologi; Infektioner och Immunitet; Mikael Sellin
- Telefon:
- 073-913 52 53
- Mobiltelefon:
- 073-913 52 53
- E-post:
- mikael.sellin@imbim.uu.se
- Besöksadress:
- BMC
Husargatan 3
752 37 UPPSALA - Postadress:
- Box 582
751 23 UPPSALA
- Akademiska meriter:
- Docent
Kort presentation
Professor i Molecylärmedicin, Infektionsbiologi
SciLifeLab PI

Publikationer
Senaste publikationer
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High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
Ingår i Cell Reports Methods, 2026
- DOI för High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
- Ladda ner fulltext (pdf) av High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
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Ingår i Nature Genetics, s. 1730-1741, 2025
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Ingår i Cell Reports, 2025
- DOI för Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
- Ladda ner fulltext (pdf) av Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
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The pcnB gene sustains Shigella flexneri virulence
Ingår i PLoS Pathogens, 2025
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Ingår i Molecular Pharmaceutics, s. 4032-4045, 2025
- DOI för Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
- Ladda ner fulltext (pdf) av Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
Alla publikationer
Artiklar i tidskrift
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High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
Ingår i Cell Reports Methods, 2026
- DOI för High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
- Ladda ner fulltext (pdf) av High-efficiency transfection of Acanthamoeba castellanii using a cationic polymer
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Ingår i Nature Genetics, s. 1730-1741, 2025
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Ingår i Cell Reports, 2025
- DOI för Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
- Ladda ner fulltext (pdf) av Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
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The pcnB gene sustains Shigella flexneri virulence
Ingår i PLoS Pathogens, 2025
-
Ingår i Molecular Pharmaceutics, s. 4032-4045, 2025
- DOI för Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
- Ladda ner fulltext (pdf) av Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
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Ingår i European Journal of Immunology, 2025
- DOI för Mast Cell Phenotypic Heterogeneity Impacts the Interplay with Pathogenic Salmonella Typhimurium Bacteria
- Ladda ner fulltext (pdf) av Mast Cell Phenotypic Heterogeneity Impacts the Interplay with Pathogenic Salmonella Typhimurium Bacteria
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Ingår i Cell Reports, 2025
- DOI för NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation
- Ladda ner fulltext (pdf) av NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation
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Ingår i mBio, s. 1-22, 2025
- DOI för Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids
- Ladda ner fulltext (pdf) av Determinants of divergent Salmonella and Shigella epithelial colonization strategies resolved in human enteroids and colonoids
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Ingår i npj Vaccines, 2025
- DOI för Matrix-M adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization
- Ladda ner fulltext (pdf) av Matrix-M adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization
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Ingår i Cell Reports, 2024
- DOI för Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation
- Ladda ner fulltext (pdf) av Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation
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Ingår i Nature Communications, 2024
- DOI för A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
- Ladda ner fulltext (pdf) av A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
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OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
Ingår i Scientific Reports, 2024
- DOI för OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
- Ladda ner fulltext (pdf) av OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
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Ingår i mSphere, 2024
- DOI för ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
- Ladda ner fulltext (pdf) av ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
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Ingår i PLoS biology, 2024
- DOI för Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution
- Ladda ner fulltext (pdf) av Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution
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Ingår i Veterinary research (Print), 2024
- DOI för Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection
- Ladda ner fulltext (pdf) av Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection
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Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2023
- DOI för Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice
- Ladda ner fulltext (pdf) av Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice
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Ingår i Chemical Science, s. 5291-5301, 2023
- DOI för Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites
- Ladda ner fulltext (pdf) av Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites
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Ingår i PLoS Pathogens, 2023
- DOI för Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection
- Ladda ner fulltext (pdf) av Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection
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Ingår i PLoS Pathogens, 2023
- DOI för Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection
- Ladda ner fulltext (pdf) av Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection
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Ingår i Journal of Cellular Physiology, s. 790-812, 2023
- DOI för The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition
- Ladda ner fulltext (pdf) av The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition
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Epithelial and microbial determinants of colonic drug distribution
Ingår i European Journal of Pharmaceutical Sciences, 2023
- DOI för Epithelial and microbial determinants of colonic drug distribution
- Ladda ner fulltext (pdf) av Epithelial and microbial determinants of colonic drug distribution
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Ingår i FEMS Microbiology Letters, 2022
- DOI för The VirF(21):VirF(30) protein ratio is affected by temperature and impacts Shigella flexneri host cell invasion
- Ladda ner fulltext (pdf) av The VirF(21):VirF(30) protein ratio is affected by temperature and impacts Shigella flexneri host cell invasion
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IgE cross-linking induces activation of human and mouse mast cell progenitors
Ingår i Journal of Allergy and Clinical Immunology, s. 1458-1463, 2022
- DOI för IgE cross-linking induces activation of human and mouse mast cell progenitors
- Ladda ner fulltext (pdf) av IgE cross-linking induces activation of human and mouse mast cell progenitors
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Ingår i Molecular Microbiology, s. 1156-1172, 2022
- DOI för A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface
- Ladda ner fulltext (pdf) av A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface
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Ingår i Molecular Oncology, s. 2330-2354, 2022
- DOI för TGF beta selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition
- Ladda ner fulltext (pdf) av TGF beta selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition
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Ingår i mBio, 2022
- DOI för High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium
- Ladda ner fulltext (pdf) av High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium
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Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2021
- DOI för Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers
- Ladda ner fulltext (pdf) av Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers
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Ingår i mBio, 2021
- DOI för Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
- Ladda ner fulltext (pdf) av Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
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Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
Ingår i PLOS ONE, 2021
- DOI för Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
- Ladda ner fulltext (pdf) av Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
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Ingår i Mucosal Immunology, s. 615-629, 2021
- DOI för Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice
- Ladda ner fulltext (pdf) av Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice
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Ingår i Journal of Experimental Medicine, 2021
- DOI för Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF
- Ladda ner fulltext (pdf) av Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF
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Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium
Ingår i PLoS Pathogens, 2020
- DOI för Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium
- Ladda ner fulltext (pdf) av Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium
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Ingår i Mucosal Immunology, s. 530-544, 2020
- DOI för Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression
- Ladda ner fulltext (pdf) av Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression
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Ingår i Cellular Microbiology, 2020
- DOI för Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes
- Ladda ner fulltext (pdf) av Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes
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Ingår i Cell Reports, s. 2665-26788.e1–e3, 2019
- DOI för Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract
- Ladda ner fulltext (pdf) av Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract
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Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
Ingår i Cellular Microbiology, 2019
- DOI för Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
- Ladda ner fulltext (pdf) av Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
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Ingår i mBio, 2019
- DOI för The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium
- Ladda ner fulltext (pdf) av The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium
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Ingår i mBio, 2019
- DOI för Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms
- Ladda ner fulltext (pdf) av Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms
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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
Ingår i Cell Death Discovery, 2019
- DOI för Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
- Ladda ner fulltext (pdf) av Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
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Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis
Ingår i Cell Host and Microbe, s. 681-69400000000, 2019
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Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
Ingår i Nature, s. 276-280, 2019
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High-avidity IgA protects the intestine by enchaining growing bacteria
Ingår i Nature, s. 498-+, 2017
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Inflammation boosts bacteriophage transfer between Salmonella spp.
Ingår i Science, s. 1211-1215, 2017
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Ingår i PLoS Pathogens, 2016
- DOI för An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection
- Ladda ner fulltext (pdf) av An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection
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Ingår i Cell Host and Microbe, 2016
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Inflammasomes of the intestinal epithelium
Ingår i Trends in immunology, s. 442-450, 2015
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A Generic Method for Design of Oligomer-Specific Antibodies
Ingår i PLOS ONE, 2014
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Ingår i Cell Host and Microbe, s. 237-248, 2014
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Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.
Ingår i Current Biology, 2014
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Ingår i PLoS Pathogens, 2014
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Ingår i Molecular Biology of the Cell, s. 1594-1607, 2014
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Ingår i Cellular Microbiology, 2014
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Ingår i Cellular Microbiology, 2013
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Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers
Ingår i Molecular Biology of the Cell, s. 4242-4255, 2012
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Ingår i PLOS ONE, 2011
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Deciphering the rules governing assembly order of mammalian septin complexes
Ingår i Molecular Biology of the Cell, s. 3152-3164, 2011
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Microtubules support a disc-like septin arrangement at the plasma membrane of mammalian cells
Ingår i Molecular Biology of the Cell, s. 4588-4601, 2011
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Ingår i Experimental Cell Research, s. 2017-2026, 2010
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Ingår i Cellular and Molecular Life Sciences (CMLS), s. 3263-3276, 2009
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Ingår i Infection and Immunity, s. 1144-1154, 2009
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Ingår i Experimental Cell Research, s. 1367-77, 2008
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Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin
Ingår i Molecular Biology of the Cell, s. 2897-906, 2008
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Ingår i Molecular and biochemical parasitology (Print), s. 225-234, 2007
Artiklar, forskningsöversikt
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Ingår i Seminars in Immunology, 2023
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Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire
Ingår i Current Opinion in Microbiology, s. 9-18, 2021
- DOI för Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire
- Ladda ner fulltext (pdf) av Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire
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Epithelial inflammasomes in the defense against Salmonella gut infection
Ingår i Current Opinion in Microbiology, s. 86-94, 2021
- DOI för Epithelial inflammasomes in the defense against Salmonella gut infection
- Ladda ner fulltext (pdf) av Epithelial inflammasomes in the defense against Salmonella gut infection
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Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens
Ingår i Journal of Molecular Biology, s. 193-206, 2018
Doktorsavhandlingar, sammanläggning
Kapitel i böcker, delar av antologi
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Ingår i Bacterial Pathogenesis, s. 295-311, Humana Press, 2023
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Ingår i Pyroptosis, s. 203-221, Humana Press, 2023