Mikael Sellin
Professor at Department of Medical Biochemistry and Microbiology; Infection and Immunity; Mikael Sellin
- Telephone:
- +46 73 913 52 53
- Mobile phone:
- +46 73 913 52 53
- E-mail:
- mikael.sellin@imbim.uu.se
- Visiting address:
- BMC
Husargatan 3
752 37 UPPSALA - Postal address:
- Box 582
751 23 UPPSALA

Publications
Recent publications
Part of Nature Communications, 2024
- DOI for A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
- Download full text (pdf) of A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
Part of Cell Reports, 2024
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
Part of Scientific Reports, 2024
- DOI for OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
- Download full text (pdf) of OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
Part of mSphere, 2024
- DOI for ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
- Download full text (pdf) of ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
Part of PLoS biology, 2024
- DOI for Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution
- Download full text (pdf) of Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution
All publications
Articles in journal
Part of Nature Communications, 2024
- DOI for A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
- Download full text (pdf) of A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
Part of Cell Reports, 2024
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
Part of Scientific Reports, 2024
- DOI for OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
- Download full text (pdf) of OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
Part of mSphere, 2024
- DOI for ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
- Download full text (pdf) of ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
Part of PLoS biology, 2024
- DOI for Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution
- Download full text (pdf) of Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution
Part of Cell Reports, 2024
- DOI for Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation
- Download full text (pdf) of Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation
Part of Veterinary research (Print), 2024
- DOI for Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection
- Download full text (pdf) of Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection
Part of Proceedings of the National Academy of Sciences of the United States of America, 2023
- DOI for Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice
- Download full text (pdf) of Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice
Part of Chemical Science, p. 5291-5301, 2023
- DOI for Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites
- Download full text (pdf) of Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites
Part of PLoS Pathogens, 2023
- DOI for Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection
- Download full text (pdf) of Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection
Part of PLoS Pathogens, 2023
- DOI for Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection
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Part of Journal of Cellular Physiology, p. 790-812, 2023
- DOI for The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition
- Download full text (pdf) of The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition
Epithelial and microbial determinants of colonic drug distribution
Part of European Journal of Pharmaceutical Sciences, 2023
- DOI for Epithelial and microbial determinants of colonic drug distribution
- Download full text (pdf) of Epithelial and microbial determinants of colonic drug distribution
Part of FEMS Microbiology Letters, 2022
- DOI for The VirF(21):VirF(30) protein ratio is affected by temperature and impacts Shigella flexneri host cell invasion
- Download full text (pdf) of The VirF(21):VirF(30) protein ratio is affected by temperature and impacts Shigella flexneri host cell invasion
Part of Molecular Oncology, p. 2330-2354, 2022
- DOI for TGF beta selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition
- Download full text (pdf) of TGF beta selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition
IgE cross-linking induces activation of human and mouse mast cell progenitors
Part of Journal of Allergy and Clinical Immunology, p. 1458-1463, 2022
- DOI for IgE cross-linking induces activation of human and mouse mast cell progenitors
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Part of Molecular Microbiology, p. 1156-1172, 2022
- DOI for A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface
- Download full text (pdf) of A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface
Part of mBio, 2022
- DOI for High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium
- Download full text (pdf) of High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium
Part of mBio, 2021
- DOI for Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
- Download full text (pdf) of Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers
Part of Proceedings of the National Academy of Sciences of the United States of America, 2021
- DOI for Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers
- Download full text (pdf) of Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers
Part of Journal of Experimental Medicine, 2021
- DOI for Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF
- Download full text (pdf) of Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF
Part of Mucosal Immunology, p. 615-629, 2021
- DOI for Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice
- Download full text (pdf) of Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice
Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
Part of PLOS ONE, 2021
- DOI for Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
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Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium
Part of PLoS Pathogens, 2020
- DOI for Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium
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Part of Mucosal Immunology, p. 530-544, 2020
- DOI for Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression
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Part of Cellular Microbiology, 2020
- DOI for Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes
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Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
Part of Cellular Microbiology, 2019
- DOI for Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
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Part of Cell Reports, p. 2665-26788.e1–e3, 2019
- DOI for Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract
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Part of mBio, 2019
- DOI for The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium
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Part of mBio, 2019
- DOI for Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms
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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
Part of Cell Death Discovery, 2019
- DOI for Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
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Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis
Part of Cell Host and Microbe, p. 681-69400000000, 2019
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
Part of Nature, p. 276-280, 2019
High-avidity IgA protects the intestine by enchaining growing bacteria
Part of Nature, p. 498-+, 2017
Inflammation boosts bacteriophage transfer between Salmonella spp.
Part of Science, p. 1211-1215, 2017
Part of PLoS Pathogens, 2016
- DOI for An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection
- Download full text (pdf) of An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection
Part of Cell Host and Microbe, 2016
Inflammasomes of the intestinal epithelium
Part of Trends in immunology, p. 442-450, 2015
A Generic Method for Design of Oligomer-Specific Antibodies
Part of PLOS ONE, 2014
Part of Cell Host and Microbe, p. 237-248, 2014
Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.
Part of Current Biology, 2014
Part of PLoS Pathogens, 2014
Part of Molecular Biology of the Cell, p. 1594-1607, 2014
Part of Cellular Microbiology, 2014
Part of Cellular Microbiology, 2013
Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers
Part of Molecular Biology of the Cell, p. 4242-4255, 2012
Part of PLOS ONE, 2011
Deciphering the rules governing assembly order of mammalian septin complexes
Part of Molecular Biology of the Cell, p. 3152-3164, 2011
Microtubules support a disc-like septin arrangement at the plasma membrane of mammalian cells
Part of Molecular Biology of the Cell, p. 4588-4601, 2011
Part of Experimental Cell Research, p. 2017-2026, 2010
Part of Cellular and Molecular Life Sciences (CMLS), p. 3263-3276, 2009
Part of Infection and Immunity, p. 1144-1154, 2009
Part of Experimental Cell Research, p. 1367-77, 2008
Global regulation of the interphase microtubule system by abundantly expressed Op18/stathmin
Part of Molecular Biology of the Cell, p. 2897-906, 2008
Part of Molecular and biochemical parasitology (Print), p. 225-234, 2007
Articles, review/survey
Part of Seminars in Immunology, 2023
Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire
Part of Current Opinion in Microbiology, p. 9-18, 2021
- DOI for Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire
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Epithelial inflammasomes in the defense against Salmonella gut infection
Part of Current Opinion in Microbiology, p. 86-94, 2021
- DOI for Epithelial inflammasomes in the defense against Salmonella gut infection
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Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens
Part of Journal of Molecular Biology, p. 193-206, 2018