Bryndis Birnir

GLP-1 selectively enhances tonic GABA_A receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus

Netsyk, Olga; Korol, Sergiy; Birnir, Bryndis; Jin, Zhe

Ingår i Frontiers in Cellular Neuroscience, 2025

• DOI för GLP-1 selectively enhances tonic GABA_A receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus
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Inhibition of the Na⁺-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4⁺ T cells

Jin, Zhe; Hammoud, Hayma; Bhandage, Amol K.; Koreli, Stasini et al.

Ingår i Frontiers in Immunology, 2025

• DOI för Inhibition of the Na⁺-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4⁺ T cells
• Ladda ner fulltext (pdf) av Inhibition of the Na⁺-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4⁺ T cells

Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial

Hill, Henrik; Lundkvist, Per; Tsatsaris, Georgios; Birnir, Bryndis et al.

Ingår i Scientific Reports, 2025

• DOI för Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
• Ladda ner fulltext (pdf) av Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial

GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Netsyk, Olga; Korol, Sergiy V; Li, Jin-ping; Birnir, Bryndis et al.

Ingår i Journal of Alzheimer's Disease, s. 420-428, 2025

• DOI för GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

Netsyk, Olga; Korol, Sergiy; Westermark, Gunilla; Birnir, Bryndis et al.

Ingår i Frontiers in Cellular Neuroscience, 2025

• DOI för Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
• Ladda ner fulltext (pdf) av Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

GLP-1 selectively enhances tonic GABA_A receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus

Netsyk, Olga; Korol, Sergiy; Birnir, Bryndis; Jin, Zhe

Ingår i Frontiers in Cellular Neuroscience, 2025

• DOI för GLP-1 selectively enhances tonic GABA_A receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus
• Ladda ner fulltext (pdf) av GLP-1 selectively enhances tonic GABA_A receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus

Inhibition of the Na⁺-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4⁺ T cells

Jin, Zhe; Hammoud, Hayma; Bhandage, Amol K.; Koreli, Stasini et al.

Ingår i Frontiers in Immunology, 2025

• DOI för Inhibition of the Na⁺-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4⁺ T cells
• Ladda ner fulltext (pdf) av Inhibition of the Na⁺-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4⁺ T cells

Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial

Hill, Henrik; Lundkvist, Per; Tsatsaris, Georgios; Birnir, Bryndis et al.

Ingår i Scientific Reports, 2025

• DOI för Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
• Ladda ner fulltext (pdf) av Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial

GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Netsyk, Olga; Korol, Sergiy V; Li, Jin-ping; Birnir, Bryndis et al.

Ingår i Journal of Alzheimer's Disease, s. 420-428, 2025

• DOI för GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

Netsyk, Olga; Korol, Sergiy; Westermark, Gunilla; Birnir, Bryndis et al.

Ingår i Frontiers in Cellular Neuroscience, 2025

• DOI för Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
• Ladda ner fulltext (pdf) av Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA_A receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells

GABA-mediated inhibition of human CD4⁺ T cell functions is enhanced by insulin but impaired by high glucose levels

Jin, Zhe; Hammoud, Hayma; Bhandage, Amol; Korol, Sergiy Vasylyovych et al.

Ingår i EBioMedicine, 2024

• DOI för GABA-mediated inhibition of human CD4⁺ T cell functions is enhanced by insulin but impaired by high glucose levels
• Ladda ner fulltext (pdf) av GABA-mediated inhibition of human CD4⁺ T cell functions is enhanced by insulin but impaired by high glucose levels

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Cotman, Andrej Emanuel; Durcik, Martina; Tiz, Davide Benedetto; Fulgheri, Federica et al.

Ingår i Journal of Medicinal Chemistry, s. 1380-1425, 2023

• DOI för Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa
• Ladda ner fulltext (pdf) av Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes

Hill, Henrik; Elksnis, Andris; Lundkvist, Per; Ubhayasekera, Kumari et al.

Ingår i Biomedicines, 2022

• DOI för Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes
• Ladda ner fulltext (pdf) av Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes

ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function

Schuster, Jens; Klar, Joakim; Khalfallah, Ayda; Laan, Loora et al.

Ingår i Frontiers in Molecular Neuroscience, 2022

• DOI för ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function
• Ladda ner fulltext (pdf) av ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function

Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease

Hammoud, Hayma; Netsyk, Olga; Tafreshiha, Atieh S.; Korol, Sergiy V. et al.

Ingår i Acta Physiologica, 2021

• DOI för Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease
• Ladda ner fulltext (pdf) av Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease

Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy

Fatima, Ambrin; Hoeber, Jan; Schuster, Jens; Koshimizu, Eriko et al.

Ingår i American Journal of Human Genetics, s. 739-748, 2021

• DOI för Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy
• Ladda ner fulltext (pdf) av Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy

Tonic GABA-activated synaptic and extrasynaptic currents in dentate gyrus granule cells and CA3 pyramidal neurons along the mouse hippocampal dorsoventral axis

Netsyk, Olga; Hammoud, Hayma; Korol, Sergiy; Jin, Zhe et al.

Ingår i Hippocampus, s. 1146-1157, 2020

• DOI för Tonic GABA-activated synaptic and extrasynaptic currents in dentate gyrus granule cells and CA3 pyramidal neurons along the mouse hippocampal dorsoventral axis
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GABA(A) Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets

Korol, Sergiy; Jin, Zhe; Birnir, Bryndis

Ingår i International Journal of Molecular Sciences, 2020

• DOI för GABA(A) Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets
• Ladda ner fulltext (pdf) av GABA(A) Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets

Gunnar Flemström's legacy in intestinal bicarbonate secretion: A homage to Gunnar Flemström and his work in intestinal bicarbonate secretion

Seidler, Ursula; Nylander, Olof; Sjöblom, Markus; Birnir, Bryndis et al.

Ingår i Acta Physiologica, 2019

• DOI för Gunnar Flemström's legacy in intestinal bicarbonate secretion: A homage to Gunnar Flemström and his work in intestinal bicarbonate secretion

Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186

Kvarnung, Malin; Shahsavani, Mansoureh; Taylan, Fulya; Moslem, Mohsen et al.

Ingår i Frontiers in Genetics, 2019

• DOI för Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186
• Ladda ner fulltext (pdf) av Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186

Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers

Bhandage, Amol K.; Cunningham, Janet L.; Jin, Zhe; Shen, Qiujin et al.

Ingår i International Journal of Molecular Sciences, 2019

• DOI för Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers
• Ladda ner fulltext (pdf) av Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers

Interferon-gamma potentiates GABA(A) receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons

Flood, Louise; Korol, Sergiy; Ekselius, Lisa; Birnir, Bryndis et al.

Ingår i Journal of Neuroimmunology, 2019

• DOI för Interferon-gamma potentiates GABA(A) receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons
• Ladda ner fulltext (pdf) av Interferon-gamma potentiates GABA(A) receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons

Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment

Schuster, Jens; Laan, Loora; Klar, Joakim; Jin, Zhe et al.

Ingår i Neurobiology of Disease, 2019

• DOI för Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment
• Ladda ner fulltext (pdf) av Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment

Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes

Bhandage, Amol; Jin, Zhe; Korol, Sergiy V; Tafreshiha, Atieh et al.

Ingår i PLOS ONE, 2018

• DOI för Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes
• Ladda ner fulltext (pdf) av Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes

Insulin enhances GABA_A receptor-mediated inhibitory currents in rat central amygdala neurons

Korol, Sergiy V.; Tafreshiha, Atieh; Bhandage, Amol K.; Birnir, Bryndis et al.

Ingår i Neuroscience Letters, s. 76-81, 2018

• DOI för Insulin enhances GABA_A receptor-mediated inhibitory currents in rat central amygdala neurons
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She is in science to stay!

Birnir, Bryndis; Eliasson, L.

Ingår i Acta Physiologica, 2018

• DOI för She is in science to stay!

Functional Characterization of Native, High-Affinity GABA_A Receptors in Human Pancreatic β Cells

Korol, Sergiy V; Jin, Zhe; Jin, Yang; Bhandage, Amol K. et al.

Ingår i EBioMedicine, 2018

• DOI för Functional Characterization of Native, High-Affinity GABA_A Receptors in Human Pancreatic β Cells
• Ladda ner fulltext (pdf) av Functional Characterization of Native, High-Affinity GABA_A Receptors in Human Pancreatic β Cells

GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4⁺ T Cells and Is Immunosuppressive in Type 1 Diabetes

Bhandage, Amol K.; Jin, Zhe; Korol, Sergiy V.; Shen, Qiujin et al.

Ingår i EBioMedicine, s. 283-294, 2018

• DOI för GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4⁺ T Cells and Is Immunosuppressive in Type 1 Diabetes
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Characterization of the gamma-aminobutyric acid signaling system in the zebrafish (danio rerio hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction

Cocco, Arianna; Rönnberg, A. M. Carolina; Jin, Zhe; André, Goncalo Igreja et al.

Ingår i Neuroscience, s. 300-321, 2017

• DOI för Characterization of the gamma-aminobutyric acid signaling system in the zebrafish (danio rerio hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction
• Ladda ner fulltext (pdf) av Characterization of the gamma-aminobutyric acid signaling system in the zebrafish (danio rerio hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction

Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

Babateen, Omar; Korol, Sergiy V.; Jin, Zhe; Bhandage, Amol K. et al.

Ingår i BMC Pharmacology & Toxicology, 2017

• DOI för Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism
• Ladda ner fulltext (pdf) av Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women

Bhandage, Amol K.; Jin, Zhe; Hellgren, Charlotte; Korol, Sergiy V. et al.

Ingår i Journal of Neuroimmunology, s. 51-58, 2017

• DOI för AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women

Normal human CD4⁺ helper T cells express Kv1.1 voltage-gated K⁺ channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway

Fellerhoff-Losch, Barbara; Korol, Sergiy V.; Ganor, Yonatan; Gu, Songhai et al.

Ingår i Journal of neural transmission, s. 137-157, 2016

• DOI för Normal human CD4⁺ helper T cells express Kv1.1 voltage-gated K⁺ channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway

GLP-1 and Exendin-4 Transiently Enhance GABA(A) Receptor-Mediated Synaptic and Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons

Korol, Sergiy V.; Jin, Zhe; Babateen, Omar; Birnir, Bryndis

Ingår i Diabetes, s. 79-89, 2015

• DOI för GLP-1 and Exendin-4 Transiently Enhance GABA(A) Receptor-Mediated Synaptic and Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons
• Ladda ner fulltext (pdf) av GLP-1 and Exendin-4 Transiently Enhance GABA(A) Receptor-Mediated Synaptic and Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons

Insulin modulates GABAA receptor-mediated neuronal inhibition in rat hippocampus and amygdala

Jin, Zhe; Korol, Sergiy V.; Jin, Yang; Birnir, Bryndis

Ingår i Acta Physiologica, s. 90-90, 2015

Modulation of GABAA receptor-mediated synaptic and tonic currents in the rat hippocampus by GLP-1, exendin-4 and diazepam

Korol, Sergiy V.; Jin, Zhe; Babateen, Omar; Birnir, Bryndis

Ingår i Acta Physiologica, s. 89-90, 2015

The mRNA expression of GABA-A, GABA-B receptor subunits and chloride transporters in peripheral blood mononuclear cells is influenced by gender, pregnancy and depression

Bhandage, Amol; Hellgren, Charlotte; Jin, Zhe; Ólafsson, Einar et al.

Ingår i Acta Physiologica, s. 91-91, 2015

Expression of GABA receptors subunits in peripheral blood mononuclear cells is gender dependent, altered in pregnancy and modified by mental health

Bhandage, Amol K.; Hellgren, Charlotte; Jin, Zhe; Olafsson, Einar B et al.

Ingår i Acta Physiologica, s. 575-585, 2015

• DOI för Expression of GABA receptors subunits in peripheral blood mononuclear cells is gender dependent, altered in pregnancy and modified by mental health

The GLP-1 Receptor Agonist Exendin-4 and Diazepam Differentially Regulate GABA_A Receptor-Mediated Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons

Korol, Sergiy V.; Jin, Zhe; Birnir, Bryndis

Ingår i PLOS ONE, 2015

• DOI för The GLP-1 Receptor Agonist Exendin-4 and Diazepam Differentially Regulate GABA_A Receptor-Mediated Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons
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Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from Human glioblastoma

Babateen, Omar; Jin, Zhe; Bhandage, Amol K.; Korol, Sergiy V et al.

Ingår i European Journal of Pharmacology, s. 101-107, 2015

• DOI för Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from Human glioblastoma

GABA-A receptor subunit expression in human peripheral blood mononuclear cells

Bhandage, Amol K.; Hellgren, Charlotte; Jin, Zhe; Olafsson, Einar et al.

Ingår i Acta Physiologica, s. 86-86, 2014

Insulin modulates GABA(A) receptor-mediated inhibition in rat amygdala neurons

Jin, Zhe; Korol, Sergiy V.; Birnir, Bryndis

Ingår i Acta Physiologica, s. 83-83, 2014

GABA(A) receptor-mediated currents in the hippocampus are transiently enhanced by glucagon-like peptide-1 receptor (GLP-1R) agonists

Korol, Sergiy V.; Jin, Zhe; Babateen, Omar M.; Birnir, Bryndis

Ingår i Acta Physiologica, s. 83-83, 2014

GABA-A receptor currents in a cell line (U3047MG) derived from a human glioblastoma tumor are enhanced by etomidate, propofol and diazepam

Babateen, Omar M.; Jin, Zhe; Bhandage, Amol K.; Korol, Sergiy V. et al.

Ingår i Acta Physiologica, s. 100-100, 2014

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

Bhandage, Amol K.; Jin, Zhe; Bazov, Igor; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, 2014

• DOI för GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

Jin, Zhe; Bhandage, Amol K; Bazov, Igor; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, s. 11, 2014

• DOI för Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

Jin, Zhe; Bhandage, Amol K.; Bazov, Igor; Kononenko, Olga et al.

Ingår i Frontiers in Cellular Neuroscience, s. 288, 2014

• DOI för Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Ingår i Journal of Endocrinology, s. 267-275, 2014

• DOI för Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
• Ladda ner fulltext (pdf) av Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

In Intact Islets Interstitial GABA Activates GABA(A) Receptors That Generate Tonic Currents in alpha-Cells

Jin, Yang; Korol, Sergiy V; Jin, Zhe; Barg, Sebastian et al.

Ingår i PLOS ONE, 2013

• DOI för In Intact Islets Interstitial GABA Activates GABA(A) Receptors That Generate Tonic Currents in alpha-Cells
• Ladda ner fulltext (pdf) av In Intact Islets Interstitial GABA Activates GABA(A) Receptors That Generate Tonic Currents in alpha-Cells

GABA is an effective immunomodulatory molecule

Jin, Zhe; Mendu, Suresh Kumar; Birnir, Bryndis

Ingår i Amino Acids, s. 87-94, 2013

• DOI för GABA is an effective immunomodulatory molecule

Monoacylglycerols Activate TRPV1-A Link between Phospholipase C and TRPV1

Zygmunt, Peter M.; Ermund, Anna; Movahed, Pouya; Andersson, David A. et al.

Ingår i PLOS ONE, 2013

• DOI för Monoacylglycerols Activate TRPV1-A Link between Phospholipase C and TRPV1
• Ladda ner fulltext (pdf) av Monoacylglycerols Activate TRPV1-A Link between Phospholipase C and TRPV1

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics

Jin, Zhe; Bazov, Igor; Kononenko, Olga; Korpi, Esa R et al.

Ingår i Frontiers in Cellular Neuroscience, 2012

• DOI för Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics
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GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium:      

Ring, Henrik; Mendu, Suresh Kumar; Shirazi-Fard, Shahrzad; Birnir, Bryndis et al.

Ingår i PLOS ONE, 2012

• DOI för GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium:      
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GABA-A channel subunit expression in human glioma correlates with tumour histology and clinical outcome

Pedder, H.; Jin, Zhe; Aronica, E.; Birnir, Bryndis et al.

Ingår i European Journal of Neurology, s. 67-67, 2012

GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome

Smits, Anja; Jin, Zhe; Elsir, Tamador; Pedder, Hugo et al.

Ingår i PLOS ONE, 2012

• DOI för GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome
• Ladda ner fulltext (pdf) av GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome

Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes

Mendu, Suresh Kumar; Bhandage, Amol; Jin, Zhe; Birnir, Bryndis

Ingår i PLOS ONE, 2012

• DOI för Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes
• Ladda ner fulltext (pdf) av Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes

GABAergic Signaling Is Linked to a Hypermigratory Phenotype in Dendritic Cells Infected by Toxoplasma gondii

Fuks, Jonas M; Arrighi, Romanico B G; Weidner, Jessica M; Kumar Mendu, Suresh et al.

Ingår i PLoS pathogens, 2012

• DOI för GABAergic Signaling Is Linked to a Hypermigratory Phenotype in Dendritic Cells Infected by Toxoplasma gondii
• Ladda ner fulltext (pdf) av GABAergic Signaling Is Linked to a Hypermigratory Phenotype in Dendritic Cells Infected by Toxoplasma gondii

gamma-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

Taneera, J.; Jin, Zhe; Jin, Yang; Muhammed, S. J. et al.

Ingår i Diabetologia, s. 1985-1994, 2012

• DOI för gamma-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

GABA-activated single-channel and tonic currents in rat brain slices

Jin, Zhe; Jin, Yang; Birnir, Bryndis

Ingår i Journal of Visualized Experiments, 2011

• DOI för GABA-activated single-channel and tonic currents in rat brain slices

Insulin reduces neuronal excitability by turning on GABA(A) channels that generate tonic current

Jin, Zhe; Jin, Yang; Kumar-Mendu, Suresh; Degerman, Eva et al.

Ingår i PLOS ONE, 2011

• DOI för Insulin reduces neuronal excitability by turning on GABA(A) channels that generate tonic current

Increased GABA(A) channel subunits expression in CD8(+) but not in CD4(+) T cells in BB rats developing diabetes compared to their congenic littermates

Mendu, Suresh Kumar; Åkesson, Lina; Jin, Zhe; Edlund, Anna et al.

Ingår i Molecular Immunology, s. 399-407, 2011

• DOI för Increased GABA(A) channel subunits expression in CD8(+) but not in CD4(+) T cells in BB rats developing diabetes compared to their congenic littermates

GABA, a natural immunomodulator of T lymphocytes

Bjurstöm, Helen; Wang, JunYang; Ericsson, Ida; Bengtsson, Martin et al.

Ingår i Journal of Neuroimmunology, s. 44-50, 2008

• DOI för GABA, a natural immunomodulator of T lymphocytes

The impact of sub-cellular location and intracellular neuronal proteins on properties of GABA(A) receptors.

Birnir, Bryndis; Korpi, Esa R

Ingår i Current pharmaceutical design, s. 3169-77, 2007

Graded response to GABA by native extrasynaptic GABA receptors.

Lindquist, Catarina E L; Birnir, Bryndis

Ingår i Journal of Neurochemistry, s. 1349-56, 2006

• DOI för Graded response to GABA by native extrasynaptic GABA receptors.

Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE.

Liu, Yawei; Teige, Ingrid; Birnir, Bryndis; Issazadeh-Navikas, Shohreh

Ingår i Nature Medicine, s. 518-25, 2006

• DOI för Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE.

The mechanism of SR95531 inhibition at GABA receptors examined in human alpha1beta1 and alpha1beta1gamma2S receptors.

Lindquist, Catarina E L; Laver, Derek R; Birnir, Bryndis

Ingår i Journal of Neurochemistry, s. 491-501, 2005

• DOI för The mechanism of SR95531 inhibition at GABA receptors examined in human alpha1beta1 and alpha1beta1gamma2S receptors.

Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists.

Movahed, Pouya; Jönsson, Bo A G; Birnir, Bryndis; Wingstrand, Johan A et al.

Ingår i Journal of Biological Chemistry, s. 38496-504, 2005

• DOI för Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists.

Penicillin blocks human alpha 1 beta 1 and alpha 1 beta 1 gamma 2S GABAA channels that open spontaneously.

Lindquist, Catarina E L; Dalziel, Julie E; Cromer, Brett A; Birnir, Bryndis

Ingår i European Journal of Pharmacology, s. 23-32, 2004

• DOI för Penicillin blocks human alpha 1 beta 1 and alpha 1 beta 1 gamma 2S GABAA channels that open spontaneously.

Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells.

Wendt, Anna; Birnir, Bryndis; Buschard, Karsten; Gromada, Jesper et al.

Ingår i Diabetes, s. 1038-45, 2004

Conductance of recombinant GABA (A) channels is increased in cells co-expressing GABA(A) receptor-associated protein.

Everitt, Andrea B; Luu, Tien; Cromer, Brett; Tierney, M Louise et al.

Ingår i Journal of Biological Chemistry, s. 21701-6, 2004

• DOI för Conductance of recombinant GABA (A) channels is increased in cells co-expressing GABA(A) receptor-associated protein.

Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

Braun, Matthias; Wendt, Anna; Birnir, Bryndis; Broman, Jonas et al.

Ingår i The Journal of General Physiology, s. 191-204, 2004

• DOI för Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

Effects of pentobarbital on GABA-activated currents in acutely-isolated rat dentate gyrus granule neurons.

Lim, M S F; Lindquist, C E L; Birnir, B

Ingår i Neuroscience Letters, s. 139-42, 2003

Evidence for inhibitory effect of the agonist gaboxadol at human alpha 1 beta 2 gamma 2S GABAA receptors.

Smith, Morten; Lindquist, Catarina E L; Birnir, Bryndis

Ingår i European Journal of Pharmacology, s. 21-6, 2003

Extrasynaptic GABA(A) channels activated by THIP are modulated by diazepam in CA1 pyramidal neurons in the rat brain hippocampal slice.

Lindquist, Catarina E L; Ebert, Bjarke; Birnir, Bryndis

Ingår i Molecular and Cellular Neuroscience, s. 250-7, 2003

Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats.

Eghbali, Mansoureh; Birnir, Bryndis; Gage, Peter W

Ingår i Journal of Physiology, s. 13-22, 2003

• DOI för Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats.

Effects of propofol on GABAA channel conductance in rat-cultured hippocampal neurons.

Eghbali, Mansoureh; Gage, Peter W; Birnir, Bryndis

Ingår i European Journal of Pharmacology, s. 75-82, 2003

GABA concentration sets the conductance of delayed GABAA channels in outside-out patches from rat hippocampal neurons.

Birnir, Bryndis; Eghbali, M; Cox, G B; Gage, P W

Ingår i Journal of Membrane Biology, s. 171-83, 2001

Heterogeneity of functional GABA(A) receptors in rat dentate gyrus neurons revealed by a change in response to drugs during the whole-cell current time-course.

Lim, M S; Birnir, Bryndis

Ingår i Neuropharmacology, s. 1034-43, 2001

Bicuculline, pentobarbital and diazepam modulate spontaneous GABA(A) channels in rat hippocampal neurons.

Birnir, Bryndis; Eghbali, M; Everitt, A B; Gage, P W

Ingår i British Journal of Pharmacology, s. 695-704, 2000

• DOI för Bicuculline, pentobarbital and diazepam modulate spontaneous GABA(A) channels in rat hippocampal neurons.

Pentobarbital modulates gamma-aminobutyric acid-activated single-channel conductance in rat cultured hippocampal neurons.

Eghbali, M; Gage, P W; Birnir, Bryndis

Ingår i Molecular Pharmacology, s. 463-9, 2000

Mutating the highly conserved second membrane-spanning region 9' leucine residue in the alpha(1) or beta(1) subunit produces subunit-specific changes in the function of human alpha(1)beta(1) gamma-aminobutyric Acid(A) receptors.

Dalziel, J E; Cox, G B; Gage, P W; Birnir, Bryndis

Ingår i Molecular Pharmacology, s. 875-82, 2000

Spontaneously opening GABA(A) channels in CA1 pyramidal neurones of rat hippocampus.

Birnir, Bryndis; Everitt, A B; Lim, M S; Gage, P W

Ingår i Journal of Membrane Biology, s. 21-9, 2000

Mutant human alpha(1)beta(1)(T262Q) GABA(A) receptors are directly activated but not modulated by pentobarbital.

Dalziel, J E; Cox, G B; Gage, P W; Birnir, Bryndis

Ingår i European Journal of Pharmacology, s. 283-6, 1999

A threonine residue in the M2 region of the beta1 subunit is needed for expression of functional alpha1beta1 GABA(A) receptors.

Dalziel, J E; Birnir, Bryndis; Everitt, A B; Tierney, M L et al.

Ingår i European Journal of Pharmacology, s. 345-8, 1999

Two threonine residues in the M2 segment of the alpha 1 beta 1 GABAA receptor are critical for ion channel function.

Tierney, M L; Birnir, Bryndis; Cromer, B; Howitt, S M et al.

Ingår i Receptors and Channels, s. 113-24, 1998

Hippocampal GABA(A) channel conductance increased by diazepam.

Eghbali, M; Curmi, J P; Birnir, Bryndis; Gage, P W

Ingår i Nature, s. 71-5, 1997

• DOI för Hippocampal GABA(A) channel conductance increased by diazepam.

Nature of the 5' residue in the M2 domain affects function of the human alpha 1 beta 1 GABAA receptor.

Birnir, Bryndis; Tierney, M L; Lim, M; Cox, G B et al.

Ingår i Synapse, s. 324-7, 1997

• DOI för Nature of the 5' residue in the M2 domain affects function of the human alpha 1 beta 1 GABAA receptor.

A structural determinant of desensitization and allosteric regulation by pentobarbitone of the GABAA receptor.

Birnir, Bryndis; Tierney, M L; Dalziel, J E; Cox, G B et al.

Ingår i Journal of Membrane Biology, s. 157-66, 1997

Effects of mutating leucine to threonine in the M2 segment of alpha1 and beta1 subunits of GABAA alpha1beta1 receptors.

Tierney, M L; Birnir, Bryndis; Pillai, N P; Clements, J D et al.

Ingår i Journal of Membrane Biology, s. 11-21, 1996

Rapid desensitization of alpha 1 beta 1 GABA A receptors expressed in Sf9 cells under optimized conditions.

Birnir, Bryndis; Tierney, M L; Pillai, N P; Cox, G B et al.

Ingår i Journal of Membrane Biology, s. 193-202, 1995

Characteristics of GABAA channels in rat dentate gyrus.

Birnir, Bryndis; Everitt, A B; Gage, P W

Ingår i Journal of Membrane Biology, s. 93-102, 1994

The influence of membrane potential on chloride channels activated by GABA in rat cultured hippocampal neurons.

Curmi, J P; Premkumar, L S; Birnir, Bryndis; Gage, P W

Ingår i Journal of Membrane Biology, s. 273-80, 1993

A combination of human alpha 1 and beta 1 subunits is required for formation of detectable GABA-activated chloride channels in Sf9 cells.

Birnir, Bryndis; Tierney, M L; Howitt, S M; Cox, G B et al.

Ingår i Proceedings of the Royal Society of London. Biological Sciences, s. 307-12, 1992

• DOI för A combination of human alpha 1 and beta 1 subunits is required for formation of detectable GABA-activated chloride channels in Sf9 cells.

Voltage-clamp studies of the Na+/glucose cotransporter cloned from rabbit small intestine.

Birnir, Bryndis; Loo, D D; Wright, E M

Ingår i Pflügers Archiv, s. 79-85, 1991

Expression and characterization of the intestinal Na+/glucose cotransporter in COS-7 cells.

Birnir, Bryndis; Lee, H S; Hediger, M A; Wright, E M

Ingår i Biochimica et Biophysica Acta, s. 100-4, 1990

Serum chemistry and evidence of renal failure in the North Atlantic fin whale population.

Lambertsen, R H; Birnir, Bryndis; Bauer, J E

Ingår i Journal of Wildlife Diseases, s. 389-96, 1986

GABAergic signalling in the immune system

Barragan, A.; Weidner, J. M.; Jin, Zhe; Korpi, E. R. et al.

Ingår i Acta Physiologica, s. 819-827, 2015

• DOI för GABAergic signalling in the immune system

GABA is an efficient immunomodulator molecule

Jin, Zhe; Mendu, Suresh Kumar; Bhandage, Amol K.; Birnir, Bryndis

Ingår i Nerve-Driven Immunity, s. 163-173, Springer, 2012

• DOI för GABA is an efficient immunomodulator molecule

In a cell-type specific manner, high-affinity GABA-A receptors participate in autocrine and paracrine GABA signaling in human pancreatic islets

Jin, Yang; Korol, Sergiy; Jin, Zhe; Laver, Derek et al.

GABA, insulin and glucose orchestrate effector functions of human CD4+ T cells

Jin, Zhe; Hammoud, Hayma; Bhandage, Amol; Korol, Sergiy et al.