Neurology

The research activity at the unit of neurology is strongly patient-oriented. Scientific questions arise from daily clinical practice and are solved by means of clinical / interventional studies and translational studies using biobank material.
Description of our research
Research fields include common neurological diseases such as epilepsy, movement disorders, acute stroke and multiple sclerosis but also sleep disorders, like narcolepsy, and more rare disorders like neurogenetic disorders, for example Huntington’s disease, and low-grade gliomas. Scientific fields like disturbances in the autonomic nervous system have been acknowledged here, and the development of treatments, have led to successful achievements of our unit.
A common focus is ”Neurotherapy”, a field where our unit for a long time achieved a strong position for developing treatments against neurological disease. Such examples are pharmacotherapy administered with pump in Parkinson’s disease, epilepsy surgery and hematopoietic stem cell transplantation (HSCT) against MS, further advanced imaging diagnostics in the mapping of brain tumours, and shunt operations in normal pressure hydrocephalus (NPH).
Group members
Research projects
- Huntington's disease and other neurogenetic diseases
- ALS and other motor neurone diseases
- Epilepsy
- MS and other neuroinflammatory diseases
- Normal pressure hydrocephalus and other corpuscular circulation disorders
- Parkinson's disease and other movement disorders
- Stroke and other cerebrovascular diseases
Publications
Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening
Part of Nature Communications, 2025
- DOI for Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening
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Brain health: Pathway to primary prevention of neurodegenerative disorders of environmental origin
Part of Journal of the Neurological Sciences, 2025
- DOI for Brain health: Pathway to primary prevention of neurodegenerative disorders of environmental origin
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Part of Brain, behavior, and immunity, p. 163-176, 2025
Part of European Journal of Neurology, 2025
- DOI for Levodopa-entacapone-carbidopa intestinal gel: Data from the Swedish national registry for Parkinson's disease
- Download full text (pdf) of Levodopa-entacapone-carbidopa intestinal gel: Data from the Swedish national registry for Parkinson's disease
Part of Journal of the American Heart Association, 2025
- DOI for Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
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Part of International Journal of Adolescence and Youth, 2025
- DOI for The use of the Strengths and Difficulties Questionnaire to assess mental health in adolescents with parents diagnosed with Amyotrophic Lateral Sclerosis
- Download full text (pdf) of The use of the Strengths and Difficulties Questionnaire to assess mental health in adolescents with parents diagnosed with Amyotrophic Lateral Sclerosis
Part of Acta Neurochirurgica, 2025
- DOI for When and how are complications suspected after shunt surgery in patients with normal pressure hydrocephalus?
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A 4‐Year Follow‐Up of Levodopa‐Entacapone‐Carbidopa Intestinal Gel Treatment in Parkinson's Disease
Part of Movement Disorders Clinical Practice, p. 1609-1612, 2024
- DOI for A 4‐Year Follow‐Up of Levodopa‐Entacapone‐Carbidopa Intestinal Gel Treatment in Parkinson's Disease
- Download full text (pdf) of A 4‐Year Follow‐Up of Levodopa‐Entacapone‐Carbidopa Intestinal Gel Treatment in Parkinson's Disease
Part of Social Science and Medicine, 2024
- DOI for Adolescents' challenging and grief-filled transitions when living with a parent with ALS: A qualitative interpretive study
- Download full text (pdf) of Adolescents' challenging and grief-filled transitions when living with a parent with ALS: A qualitative interpretive study
Part of International Journal of Obesity, p. 1300-1306, 2024
- DOI for Associations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals
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Part of Epilepsia Open, p. 1611-1617, 2024
- DOI for Cardiovascular risk factor assessment in late-onset seizures: A study protocol to assess the value of structured intervention
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Part of iScience, 2024
- DOI for Cerebrospinal fluid and plasma concentrations of the inflammatory marker soluble CD27 in a large surgical population
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Part of Journal of the Neurological Sciences, 2024
- DOI for Cerebrospinal fluid glial fibrillary acidic protein, in contrast to amyloid beta protein, is associated with disease symptoms in Huntington's disease
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Part of Multiple Sclerosis and Related Disorders, 2024
- DOI for Cerebrospinal fluid mtDNA concentrations are increased in multiple sclerosis and were normalized after intervention with autologous hematopoietic stem cell transplantation
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Part of Dementia and Geriatric Cognitive Disorders, p. 277-295, 2024
Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
Part of Journal of Clinical Medicine, 2024
- DOI for Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
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Part of Annals of Neurology, p. 678-693, 2024
- DOI for COMBAT-MS: A Population-Based Observational Cohort Study Addressing the Benefit-Risk Balance of Multiple Sclerosis Therapies Compared with Rituximab
- Download full text (pdf) of COMBAT-MS: A Population-Based Observational Cohort Study Addressing the Benefit-Risk Balance of Multiple Sclerosis Therapies Compared with Rituximab
Part of Physica medica (Testo stampato), 2024
- DOI for Comparison of quantitative [11C]PE2I brain PET studies between an integrated PET/MR and a stand-alone PET system
- Download full text (pdf) of Comparison of quantitative [11C]PE2I brain PET studies between an integrated PET/MR and a stand-alone PET system
Part of NEUROTRAUMA REPORTS, p. 857-873, 2024
- DOI for Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid
- Download full text (pdf) of Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid
Part of Journal of the Neurological Sciences, 2024
- DOI for Developing education in environmental health and medicine focusing on neurology: Initiatives in Sweden (the UPRISE model), France, and Turkey
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Part of Journal of Neurology, Neurosurgery and Psychiatry, p. 775-783, 2024
Part of Scientific Reports, 2024
- DOI for Estimation bias and agreement limits between two common self-report methods of habitual sleep duration in epidemiological surveys
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Evaluation of [11C]UCB-A positron emission tomography in human brains
Part of EJNMMI Research, 2024
- DOI for Evaluation of [11C]UCB-A positron emission tomography in human brains
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Evoked potentials after autologous hematopoietic stem cell transplantation for multiple sclerosis
Part of Multiple Sclerosis and Related Disorders, 2024
- DOI for Evoked potentials after autologous hematopoietic stem cell transplantation for multiple sclerosis
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Part of PLOS ONE, 2024
- DOI for Experiences of being treated with autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: A qualitative interview study
- Download full text (pdf) of Experiences of being treated with autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: A qualitative interview study
Part of European Journal of Pain, p. 929-942, 2024
- DOI for Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
- Download full text (pdf) of Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
Part of International Journal of Laboratory Hematology, p. 42-49, 2024
- DOI for Extracellular vesicles in plasma and cerebrospinal fluid in patients with COVID-19 and neurological symptoms
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Part of BMJ Open, 2024
- DOI for Factors associated with changes in walking performance in individuals 3 months after stroke or TIA: secondary analyses from a randomised controlled trial of SMS-delivered training instructions in Sweden
- Download full text (pdf) of Factors associated with changes in walking performance in individuals 3 months after stroke or TIA: secondary analyses from a randomised controlled trial of SMS-delivered training instructions in Sweden
Finding stroke with a blood test
2024
Habitual short sleepers with pre-existing medical conditions are at higher risk of Long COVID
Part of Journal of Clinical Sleep Medicine (JCSM), p. 111-119, 2024
Part of Journal of Neurology, Neurosurgery and Psychiatry, p. 125-133, 2024
- DOI for Haematopoietic stem cell transplantation for treatment of relapsing-remitting multiple sclerosis in Sweden: an observational cohort study
- Download full text (pdf) of Haematopoietic stem cell transplantation for treatment of relapsing-remitting multiple sclerosis in Sweden: an observational cohort study
Part of International Journal of Stroke, p. 798-808, 2024
- DOI for Individual patient data meta-analysis of the effects of fluoxetine on functional outcomes after acute stroke
- Download full text (pdf) of Individual patient data meta-analysis of the effects of fluoxetine on functional outcomes after acute stroke
Part of CEREBRAL CIRCULATION-COGNITION AND BEHAVIOR, 2024
- DOI for Is the difference real, is the difference relevant: the minimal detectable and clinically important changes in the Montreal Cognitive Assessment
- Download full text (pdf) of Is the difference real, is the difference relevant: the minimal detectable and clinically important changes in the Montreal Cognitive Assessment
Part of BMC Neurology, 2024
- DOI for Large variations in atrial fibrillation screening practice after ischemic stroke and transient ischemic attack in Sweden: a survey study
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Motor Efficacy of Subcutaneous DIZ102, Intravenous DIZ101 or Intestinal Levodopa/Carbidopa Infusion
Part of Movement Disorders Clinical Practice, p. 1095-1102, 2024
- DOI for Motor Efficacy of Subcutaneous DIZ102, Intravenous DIZ101 or Intestinal Levodopa/Carbidopa Infusion
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Neurofilament Light Chain and Risk of Stroke in Patients With Atrial Fibrillation
Part of Circulation, p. 1090-1100, 2024
Nightmare frequency is a risk factor for suicidal ideation during the COVID-19 pandemic
Part of Journal of Sleep Research, 2024
Part of Journal of Neuroimaging, p. 612-618, 2024
- DOI for Quantitative brain stem assessment in discriminating neurodegenerative disorders from normal pressure hydrocephalus
- Download full text (pdf) of Quantitative brain stem assessment in discriminating neurodegenerative disorders from normal pressure hydrocephalus
Reduced long-term mortality after successful resective epilepsy surgery: a population-based study
Part of Journal of Neurology, Neurosurgery and Psychiatry, p. 249-255, 2024
- DOI for Reduced long-term mortality after successful resective epilepsy surgery: a population-based study
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Part of Human Molecular Genetics, p. 1966-1974, 2024
- DOI for Small striatal huntingtin inclusions in patients with motor neuron disease with reduced penetrance and intermediate HTT gene expansions
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Tenecteplase compared to alteplase in real-world outcome: A Swedish Stroke Register study
Part of Upsala Journal of Medical Sciences, 2024
- DOI for Tenecteplase compared to alteplase in real-world outcome: A Swedish Stroke Register study
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Part of Molecular Psychiatry, 2024
Part of Journal of Neurosurgery, p. 1493-1500, 2024
- DOI for Volumetric effect of shunt adjustments in normal pressure hydrocephalus: a randomized, double-blind trial
- Download full text (pdf) of Volumetric effect of shunt adjustments in normal pressure hydrocephalus: a randomized, double-blind trial
A comprehensive diagnostic approach in suspected neurosarcoidosis
Part of Scientific Reports, 2023
- DOI for A comprehensive diagnostic approach in suspected neurosarcoidosis
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Absence of Oligoclonal Bands in Multiple Sclerosis: A Call for Differential Diagnosis
Part of Journal of Clinical Medicine, 2023
- DOI for Absence of Oligoclonal Bands in Multiple Sclerosis: A Call for Differential Diagnosis
- Download full text (pdf) of Absence of Oligoclonal Bands in Multiple Sclerosis: A Call for Differential Diagnosis
Part of PLOS ONE, 2023
- DOI for Anti-Müllerian hormone and pregnancy after autologous hematopoietic stem cell transplantation for multiple sclerosis
- Download full text (pdf) of Anti-Müllerian hormone and pregnancy after autologous hematopoietic stem cell transplantation for multiple sclerosis
Part of Fluids and Barriers of the CNS, 2023
- DOI for Association between ventricular CSF biomarkers and outcome after shunt surgery in idiopathic normal pressure hydrocephalus
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Part of BMC Public Health, 2023
- DOI for Associations between changes in habitual sleep duration and lower self-rated health among COVID-19 survivors: findings from a survey across 16 countries/regions
- Download full text (pdf) of Associations between changes in habitual sleep duration and lower self-rated health among COVID-19 survivors: findings from a survey across 16 countries/regions
Part of Frontiers in Genetics, 2023
- DOI for Case report: a novel deep intronic splice-altering variant in DMD as a cause of Becker muscular dystrophy
- Download full text (pdf) of Case report: a novel deep intronic splice-altering variant in DMD as a cause of Becker muscular dystrophy
Part of Neurology, 2023
- DOI for Cerebrospinal fluid concentrations of CXCL13 and sCD27 are decreased after autologous hematopoietic stem cell transplantation for multiple sclerosis
- Download full text (pdf) of Cerebrospinal fluid concentrations of CXCL13 and sCD27 are decreased after autologous hematopoietic stem cell transplantation for multiple sclerosis