Neurologi

Forskningsaktiviteten på enheten för neurologi är starkt patientorienterad. I den kliniska verksamheten väcks dagligen vetenskapliga frågor vilka vi försöker lösa med stöd av resultat från bl.a. interventions-, observations- och epidemiologiska studier samt translationella studier där material från biobank används.
Beskrivning av vår forskning
Våra forskningsområden inkluderar vanliga neurologiska sjukdomar som epilepsi, motorikstörningar, akut stroke och multipel skleros, men också sömnsjukdomar, som narkolepsi, och ännu mer ovanliga tillstånd som neurogenetiska sjukdomar, till exempel Huntingtons sjukdom och låggradiga gliom. Områden som störningar i autonoma nervsystemet och utveckling av behandlingar har varit framträdande sedan länge.
Ett gemensamt fokus kan innefattas i begreppet ”Neuroterapi”, där vår enhet sedan länge befäst en stark ställning för att utveckla behandling vid sjukdom. Sådana exempel är läkemedelsbehandling med pump vid svår Parkinsons sjukdom, epilepsikirurgi och stamcellstransplantation mot MS, vidare avancerad bilddiagnostik vid kartläggning av hjärntumörer, samt shuntoperation vid normaltryckshydrocefalus (NPH).
Gruppmedlemmar
Forskningsprojekt
- Huntingtons sjukdom och andra neurogenetiska sjukdomar
- ALS och andra motorneuronsjukdomar
- Epilepsi
- MS och andra neuroinflammatoriska sjukdomar
- Normaltryckshydrocefalus och andra likvorcirkulationsstörinngar
- Parkinsons sjukdom och andra rörelsestörningar
- Stroke och andra cerebrovaskulära sjukdomar
Publikationer
Inflammatory protein profiles and shunt response in iNPH
Ingår i Fluids and Barriers of the CNS, 2026
- DOI för Inflammatory protein profiles and shunt response in iNPH
- Ladda ner fulltext (pdf) av Inflammatory protein profiles and shunt response in iNPH
Multiple Sclerosis: A Comprehensive Journey from Oligoclonal Bands to Cutting-Edge MRI Techniques
2026
Numinous-like symptoms in epilepsy and/or insular tumors: A hospital cohort study
Ingår i Epilepsy & Behavior, 2026
- DOI för Numinous-like symptoms in epilepsy and/or insular tumors: A hospital cohort study
- Ladda ner fulltext (pdf) av Numinous-like symptoms in epilepsy and/or insular tumors: A hospital cohort study
Ingår i Journal of Sleep Research, 2026
- DOI för Prevalence Rates of Frequent Dream Recall and Nightmares by Age, Gender and Sleep Duration in 16 Countries
- Ladda ner fulltext (pdf) av Prevalence Rates of Frequent Dream Recall and Nightmares by Age, Gender and Sleep Duration in 16 Countries
Ingår i Radiography, 2026
- DOI för Radiation doses in ventriculoperitoneal shunt catheter imaging - Comparing traditional plain radiography with computed tomography and photon counting computed tomography.
- Ladda ner fulltext (pdf) av Radiation doses in ventriculoperitoneal shunt catheter imaging - Comparing traditional plain radiography with computed tomography and photon counting computed tomography.
Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
Ingår i JACC: Advances, 2026
- DOI för Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
- Ladda ner fulltext (pdf) av Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening
Ingår i Nature Communications, 2025
- DOI för Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening
- Ladda ner fulltext (pdf) av Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening
Ingår i Fluids and Barriers of the CNS, 2025
- DOI för Blinded gait assessment in idiopathic normal pressure hydrocephalus: reliability and correlation with clinical and patient-reported outcomes
- Ladda ner fulltext (pdf) av Blinded gait assessment in idiopathic normal pressure hydrocephalus: reliability and correlation with clinical and patient-reported outcomes
Brain health: Pathway to primary prevention of neurodegenerative disorders of environmental origin
Ingår i Journal of the Neurological Sciences, 2025
- DOI för Brain health: Pathway to primary prevention of neurodegenerative disorders of environmental origin
- Ladda ner fulltext (pdf) av Brain health: Pathway to primary prevention of neurodegenerative disorders of environmental origin
Ingår i Brain, behavior, and immunity, s. 163-176, 2025
Ingår i World Neurosurgery, 2025
- DOI för Chronic, Shunt-Dependent Hydrocephalus in Aneurysmal Subarachnoid Hemorrhage: Incidence, Risk Factors, Clinical Phenotypes, and Outcome
- Ladda ner fulltext (pdf) av Chronic, Shunt-Dependent Hydrocephalus in Aneurysmal Subarachnoid Hemorrhage: Incidence, Risk Factors, Clinical Phenotypes, and Outcome
Ingår i Journal of the Neurological Sciences, 2025
- DOI för Climate change impacts the symptomology and healthcare of multiple sclerosis patients through fatigue and heat sensitivity: A systematic review
- Ladda ner fulltext (pdf) av Climate change impacts the symptomology and healthcare of multiple sclerosis patients through fatigue and heat sensitivity: A systematic review
Climate-related challenges to brain health: A European perspective review
Ingår i Revue Neurologique, 2025
Ingår i The Lancet, s. 43-51, 2025
- DOI för Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST)
- Ladda ner fulltext (pdf) av Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST)
Ingår i Journal of neural transmission, 2025
Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Ingår i Journal of Sleep Research, 2025
- DOI för Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
- Ladda ner fulltext (pdf) av Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Ingår i Upsala Journal of Medical Sciences, 2025
- DOI för Enhancing Recruitment Using Teleconference and Commitment Contract (ERUTECC): a stepped wedge cluster randomised trial within the EFFECTS trial
- Ladda ner fulltext (pdf) av Enhancing Recruitment Using Teleconference and Commitment Contract (ERUTECC): a stepped wedge cluster randomised trial within the EFFECTS trial
Ingår i International Journal of Stroke, s. 540-549, 2025
Genetic Risk Factors for Poor Cognitive Outcome Following Brain Insult-A Systematic Review
Ingår i Brain and Behavior, 2025
Healthcare Burden and Productivity Loss Due to Narcolepsy in Sweden
Ingår i Clocks & Sleep, 2025
- DOI för Healthcare Burden and Productivity Loss Due to Narcolepsy in Sweden
- Ladda ner fulltext (pdf) av Healthcare Burden and Productivity Loss Due to Narcolepsy in Sweden
Ingår i Physiotherapy Theory and Practice, s. 763-771, 2025
- DOI för “I’m still the person I am. Not the body it has become.”: An active but challenging life with cervical dystonia
- Ladda ner fulltext (pdf) av “I’m still the person I am. Not the body it has become.”: An active but challenging life with cervical dystonia
Ingår i Injury, 2025
- DOI för Injury recidivism in women with personality disorders reflects an increased risk for both natural and unnatural death
- Ladda ner fulltext (pdf) av Injury recidivism in women with personality disorders reflects an increased risk for both natural and unnatural death
Ingår i European Journal of Neurology, 2025
- DOI för Levodopa-entacapone-carbidopa intestinal gel: Data from the Swedish national registry for Parkinson's disease
- Ladda ner fulltext (pdf) av Levodopa-entacapone-carbidopa intestinal gel: Data from the Swedish national registry for Parkinson's disease
Ingår i Sleep Medicine, 2025
- DOI för Long COVID as a risk factor for hypersomnolence and fatigue: insights from the 2nd International Covid Sleep Study Collaboration (ICOSS-2)
- Ladda ner fulltext (pdf) av Long COVID as a risk factor for hypersomnolence and fatigue: insights from the 2nd International Covid Sleep Study Collaboration (ICOSS-2)
Lucid Dreaming: Not Just Awareness, but Agency
Ingår i Journal of Sleep Research, 2025
- DOI för Lucid Dreaming: Not Just Awareness, but Agency
- Ladda ner fulltext (pdf) av Lucid Dreaming: Not Just Awareness, but Agency
Ingår i Journal of the American Heart Association, 2025
- DOI för Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
- Ladda ner fulltext (pdf) av Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
Ingår i Neurology, 2025
- DOI för Nicotine, Alcohol Consumption, and Risk of Myasthenia Gravis Results From the Swedish Nationwide GEMG Study
- Ladda ner fulltext (pdf) av Nicotine, Alcohol Consumption, and Risk of Myasthenia Gravis Results From the Swedish Nationwide GEMG Study
Patient experiences of narcolepsy and idiopathic hypersomnia in the Nordics: a patient journey map
Ingår i Journal of Sleep Research, 2025
- DOI för Patient experiences of narcolepsy and idiopathic hypersomnia in the Nordics: a patient journey map
- Ladda ner fulltext (pdf) av Patient experiences of narcolepsy and idiopathic hypersomnia in the Nordics: a patient journey map
Ingår i Frontiers in Neurology, 2025
- DOI för Plasma cholinergic markers are associated with post-stroke walking recovery-revisiting the STROKEWALK study
- Ladda ner fulltext (pdf) av Plasma cholinergic markers are associated with post-stroke walking recovery-revisiting the STROKEWALK study
Plasma Profiles of Neuroglial Injury Biomarkers after Ischemic Stroke
Ingår i Translational Stroke Research, 2025
Ingår i Journal of the Neurological Sciences, 2025
Ingår i European Journal of Neurology, 2025
- DOI för Rituximab in New-Onset Generalized Myasthenia Gravis: Long-Term Follow-Up of the RINOMAX Clinical Trial
- Ladda ner fulltext (pdf) av Rituximab in New-Onset Generalized Myasthenia Gravis: Long-Term Follow-Up of the RINOMAX Clinical Trial
Ingår i Journal of Sleep Research, 2025
Subcortical Brain Regions Associated With Seizure Risk in Patients With IDH Mutated Diffuse Gliomas
Ingår i Brain and Behavior, 2025
- DOI för Subcortical Brain Regions Associated With Seizure Risk in Patients With IDH Mutated Diffuse Gliomas
- Ladda ner fulltext (pdf) av Subcortical Brain Regions Associated With Seizure Risk in Patients With IDH Mutated Diffuse Gliomas
The Prognostic Test Accuracy of the Short and Standard Forms of the Montreal Cognitive Assessment
Ingår i Cerebrovascular Diseases, s. 308-314, 2025
- DOI för The Prognostic Test Accuracy of the Short and Standard Forms of the Montreal Cognitive Assessment
- Ladda ner fulltext (pdf) av The Prognostic Test Accuracy of the Short and Standard Forms of the Montreal Cognitive Assessment
Ingår i International Journal of Adolescence and Youth, 2025
- DOI för The use of the Strengths and Difficulties Questionnaire to assess mental health in adolescents with parents diagnosed with Amyotrophic Lateral Sclerosis
- Ladda ner fulltext (pdf) av The use of the Strengths and Difficulties Questionnaire to assess mental health in adolescents with parents diagnosed with Amyotrophic Lateral Sclerosis
Ingår i Neurology and Therapy, s. 801-812, 2025
- DOI för Therapies for Advanced Parkinson's Disease in Sweden: A Cost-Effectiveness Analysis Using Real-World Data
- Ladda ner fulltext (pdf) av Therapies for Advanced Parkinson's Disease in Sweden: A Cost-Effectiveness Analysis Using Real-World Data
Transformed Parenthood in the Face of ALS: A Profound Struggle for Both Ill Parents and Co-parents
Ingår i Global Qualitative Nursing Research, 2025
- DOI för Transformed Parenthood in the Face of ALS: A Profound Struggle for Both Ill Parents and Co-parents
- Ladda ner fulltext (pdf) av Transformed Parenthood in the Face of ALS: A Profound Struggle for Both Ill Parents and Co-parents
Warfare as an environmental health threat
Ingår i Journal of the Neurological Sciences, 2025
Ingår i Acta Neurochirurgica, 2025
- DOI för When and how are complications suspected after shunt surgery in patients with normal pressure hydrocephalus?
- Ladda ner fulltext (pdf) av When and how are complications suspected after shunt surgery in patients with normal pressure hydrocephalus?
A 4‐Year Follow‐Up of Levodopa‐Entacapone‐Carbidopa Intestinal Gel Treatment in Parkinson's Disease
Ingår i Movement Disorders Clinical Practice, s. 1609-1612, 2024
- DOI för A 4‐Year Follow‐Up of Levodopa‐Entacapone‐Carbidopa Intestinal Gel Treatment in Parkinson's Disease
- Ladda ner fulltext (pdf) av A 4‐Year Follow‐Up of Levodopa‐Entacapone‐Carbidopa Intestinal Gel Treatment in Parkinson's Disease
Ingår i Social Science and Medicine, 2024
- DOI för Adolescents' challenging and grief-filled transitions when living with a parent with ALS: A qualitative interpretive study
- Ladda ner fulltext (pdf) av Adolescents' challenging and grief-filled transitions when living with a parent with ALS: A qualitative interpretive study
2024
- DOI för Assessing CT-based Volumetric Analysis via Transfer Learning with MRI and Manual Labels for Idiopathic Normal Pressure Hydrocephalus.
- Ladda ner fulltext (pdf) av Assessing CT-based Volumetric Analysis via Transfer Learning with MRI and Manual Labels for Idiopathic Normal Pressure Hydrocephalus.
Ingår i International Journal of Obesity, s. 1300-1306, 2024
- DOI för Associations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals
- Ladda ner fulltext (pdf) av Associations between obesity, a composite risk score for probable long COVID, and sleep problems in SARS-CoV-2 vaccinated individuals
Ingår i Epilepsia Open, s. 1611-1617, 2024
- DOI för Cardiovascular risk factor assessment in late-onset seizures: A study protocol to assess the value of structured intervention
- Ladda ner fulltext (pdf) av Cardiovascular risk factor assessment in late-onset seizures: A study protocol to assess the value of structured intervention
Ingår i iScience, 2024
- DOI för Cerebrospinal fluid and plasma concentrations of the inflammatory marker soluble CD27 in a large surgical population
- Ladda ner fulltext (pdf) av Cerebrospinal fluid and plasma concentrations of the inflammatory marker soluble CD27 in a large surgical population
Ingår i Journal of the Neurological Sciences, 2024
- DOI för Cerebrospinal fluid glial fibrillary acidic protein, in contrast to amyloid beta protein, is associated with disease symptoms in Huntington's disease
- Ladda ner fulltext (pdf) av Cerebrospinal fluid glial fibrillary acidic protein, in contrast to amyloid beta protein, is associated with disease symptoms in Huntington's disease
Ingår i Multiple Sclerosis and Related Disorders, 2024
- DOI för Cerebrospinal fluid mtDNA concentrations are increased in multiple sclerosis and were normalized after intervention with autologous hematopoietic stem cell transplantation
- Ladda ner fulltext (pdf) av Cerebrospinal fluid mtDNA concentrations are increased in multiple sclerosis and were normalized after intervention with autologous hematopoietic stem cell transplantation
Ingår i Dementia and Geriatric Cognitive Disorders, s. 277-295, 2024
Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
Ingår i Journal of Clinical Medicine, 2024
- DOI för Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden
- Ladda ner fulltext (pdf) av Characterization of the Increase in Narcolepsy following the 2009 H1N1 Pandemic in Sweden