Maia labb

Vi strävar efter nya sätt att utforska den underbart komplexa världen av strukturell dynamik på nanoskala. Vi är inriktade på utveckling av linsfria avbildningsmetoder med röntgenstrålar, med användning av röntgenfri-elektronlaser som en kraftfull koherent ljuskälla.Ett vanligt tema för många moderna bildtekniker är den ökande komplexiteten i experimentella inställningar. liksom dataanalysen. Vårt laboratorium fokuserar både på att bygga ny instrumentering, till exempel leverans av provfri provtagning för röntgenundersökningar av enstaka partikelavbildning, liksom att skapa algoritmer för att analysera de resulterande data. Denna samdesign av alla delar av experimentet är avgörande för framgång och kräver ett brett spektrum av expertis, från biologi till fysiker och datavetenskap, vilket resulterar i en mycket samarbetsvillig och tvärvetenskaplig miljö.
Populärvetenskaplig presentation
...
Forskning
...
Gruppmedlemmar
Publikationer
Ingår i Journal of the American Chemical Society, s. 19555-19565, 2024
- DOI för Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions
- Ladda ner fulltext (pdf) av Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions
Ingår i Journal of Synchrotron Radiation, s. 222-232, 2024
- DOI för Enhancing electrospray ionization efficiency for particle transmission through an aerodynamic lens stack
- Ladda ner fulltext (pdf) av Enhancing electrospray ionization efficiency for particle transmission through an aerodynamic lens stack
Helium-electrospray improves sample delivery in X-ray single-particle imaging experiments
Ingår i Scientific Reports, 2024
- DOI för Helium-electrospray improves sample delivery in X-ray single-particle imaging experiments
- Ladda ner fulltext (pdf) av Helium-electrospray improves sample delivery in X-ray single-particle imaging experiments
Ingår i Nature Methods, s. 1608-1611, 2024
- DOI för Microsecond time-resolved X-ray scattering by utilizing MHz repetition rate at second-generation XFELs
- Ladda ner fulltext (pdf) av Microsecond time-resolved X-ray scattering by utilizing MHz repetition rate at second-generation XFELs
Observation of a single protein by ultrafast X-ray diffraction
Ingår i Light, 2024
- DOI för Observation of a single protein by ultrafast X-ray diffraction
- Ladda ner fulltext (pdf) av Observation of a single protein by ultrafast X-ray diffraction
Resolving Nonequilibrium Shape Variations among Millions of Gold Nanoparticles
Ingår i ACS Nano, s. 15576-15589, 2024
- DOI för Resolving Nonequilibrium Shape Variations among Millions of Gold Nanoparticles
- Ladda ner fulltext (pdf) av Resolving Nonequilibrium Shape Variations among Millions of Gold Nanoparticles
3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers
Ingår i IUCrJ, s. 662-670, 2023
- DOI för 3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers
- Ladda ner fulltext (pdf) av 3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers
Noise reduction and mask removal neural network for X-ray single-particle imaging
Ingår i Journal of applied crystallography, s. 122-132, 2022
- DOI för Noise reduction and mask removal neural network for X-ray single-particle imaging
- Ladda ner fulltext (pdf) av Noise reduction and mask removal neural network for X-ray single-particle imaging
Ingår i IUCrJ, s. 204-214, 2022
- DOI för Unsupervised learning approaches to characterizing heterogeneous samples using X-ray single-particle imaging
- Ladda ner fulltext (pdf) av Unsupervised learning approaches to characterizing heterogeneous samples using X-ray single-particle imaging
3D diffractive imaging of nanoparticle ensembles using an x-ray laser
Ingår i Optica, s. 15-23, 2021
- DOI för 3D diffractive imaging of nanoparticle ensembles using an x-ray laser
- Ladda ner fulltext (pdf) av 3D diffractive imaging of nanoparticle ensembles using an x-ray laser
Introduction to the special issue on Ptychography: software and technical developments
Ingår i Journal of applied crystallography, s. 384-385, 2021
Ptychographic wavefront characterization for single-particle imaging at x-ray lasers
Ingår i Optica, s. 551-562, 2021
- DOI för Ptychographic wavefront characterization for single-particle imaging at x-ray lasers
- Ladda ner fulltext (pdf) av Ptychographic wavefront characterization for single-particle imaging at x-ray lasers
Acquired Functional Capsid Structures in Metazoan Totivirus-like dsRNA Virus
Ingår i Structure, s. 888-+, 2020
Ingår i Scientific Data, 2020
- DOI för Diffraction data from aerosolized Coliphage PR772 virus particles imaged with the Linac Coherent Light Source
- Ladda ner fulltext (pdf) av Diffraction data from aerosolized Coliphage PR772 virus particles imaged with the Linac Coherent Light Source
Megahertz single-particle imaging at the European XFEL
Ingår i Communications Physics, 2020
- DOI för Megahertz single-particle imaging at the European XFEL
- Ladda ner fulltext (pdf) av Megahertz single-particle imaging at the European XFEL
Ingår i Structural Dynamics, 2020
- DOI för Perspectives on single particle imaging with x rays at the advent of high repetition rate x-ray free electron laser sources
- Ladda ner fulltext (pdf) av Perspectives on single particle imaging with x rays at the advent of high repetition rate x-ray free electron laser sources
Pulse-to-pulse wavefront sensing at free-electron lasers using ptychography
Ingår i Journal of applied crystallography, s. 949-956, 2020
- DOI för Pulse-to-pulse wavefront sensing at free-electron lasers using ptychography
- Ladda ner fulltext (pdf) av Pulse-to-pulse wavefront sensing at free-electron lasers using ptychography
The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters
Ingår i Nature Communications, 2020
- DOI för The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters
- Ladda ner fulltext (pdf) av The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters
Three-Dimensional Coherent Bragg Imaging of Rotating Nanoparticles
Ingår i Physical Review Letters, 2020
- DOI för Three-Dimensional Coherent Bragg Imaging of Rotating Nanoparticles
- Ladda ner fulltext (pdf) av Three-Dimensional Coherent Bragg Imaging of Rotating Nanoparticles
Electrospray sample injection for single-particle imaging with x-ray lasers
Ingår i Science Advances, 2019
Evaluation of serial crystallographic structure determination within megahertz pulse trains
Ingår i Structural Dynamics, 2019
- DOI för Evaluation of serial crystallographic structure determination within megahertz pulse trains
- Ladda ner fulltext (pdf) av Evaluation of serial crystallographic structure determination within megahertz pulse trains
A statistical approach to detect protein complexes at X-ray free electron laser facilities
Ingår i Communications Physics, 2018
Ingår i Nature Scientific Data, 2018
Ingår i IUCrJ, s. 531-541, 2018
Cryo-EM structure of a Marseilleviridae virus particle reveals a large internal microassembly
Ingår i Virology, s. 239-245, 2018
Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles
Ingår i Nature Photonics, s. 150-153, 2018
Megahertz serial crystallography
Ingår i Nature Communications, 2018
- DOI för Megahertz serial crystallography
- Ladda ner fulltext (pdf) av Megahertz serial crystallography
Rayleigh-scattering microscopy for tracking and sizing nanoparticles in focused aerosol beams
Ingår i IUCrJ, s. 673-680, 2018
- DOI för Rayleigh-scattering microscopy for tracking and sizing nanoparticles in focused aerosol beams
- Ladda ner fulltext (pdf) av Rayleigh-scattering microscopy for tracking and sizing nanoparticles in focused aerosol beams
Single-particle imaging without symmetry constraints at an X-ray free-electron laser
Ingår i IUCrJ, s. 727-736, 2018
- DOI för Single-particle imaging without symmetry constraints at an X-ray free-electron laser
- Ladda ner fulltext (pdf) av Single-particle imaging without symmetry constraints at an X-ray free-electron laser
Three-dimensional localization of nanoscale battery reactions using soft X-ray tomography
Ingår i Nature Communications, 2018
- DOI för Three-dimensional localization of nanoscale battery reactions using soft X-ray tomography
- Ladda ner fulltext (pdf) av Three-dimensional localization of nanoscale battery reactions using soft X-ray tomography
Coherent soft X-ray diffraction imaging of Coliphage PR772 at the Linac coherent light source
Ingår i Scientific Data, 2017
Correlations in scattered X-ray laser pulses reveal nanoscale structural features of viruses
Ingår i Physical Review Letters, 2017
Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses
Ingår i IUCrJ, s. 251-262, 2017
Nanosurveyor: a framework for real-time data processing
Ingår i Advanced Structural and Chemical Imaging, 2017
- DOI för Nanosurveyor: a framework for real-time data processing
- Ladda ner fulltext (pdf) av Nanosurveyor: a framework for real-time data processing
Near-edge X-ray refraction fine structure microscopy
Ingår i Applied Physics Letters, 2017
Ingår i Scientific Reports, 2017
- DOI för Structural variability and complexity of the giant Pithovirus sibericum particle revealed by high-voltage electron cryo-tomography and energy-filtered electron cryo-microscopy
- Ladda ner fulltext (pdf) av Structural variability and complexity of the giant Pithovirus sibericum particle revealed by high-voltage electron cryo-tomography and energy-filtered electron cryo-microscopy
A data set from flash X-ray imaging of carboxysomes
Ingår i Scientific Data, 2016
- DOI för A data set from flash X-ray imaging of carboxysomes
- Ladda ner fulltext (pdf) av A data set from flash X-ray imaging of carboxysomes
CCP-FEL: a collection of computer programs for free-electron laser research
Ingår i Journal of applied crystallography, s. 1117-1120, 2016
Ingår i Scientific Data, 2016
Data publication with the structural biology data grid supports live analysis
Ingår i Nature Communications, 2016
- DOI för Data publication with the structural biology data grid supports live analysis
- Ladda ner fulltext (pdf) av Data publication with the structural biology data grid supports live analysis
Hummingbird: monitoring and analyzing flash X-ray imaging experiments in real time
Ingår i Journal of applied crystallography, s. 1042-1047, 2016
Open data set of live cyanobacterial cells imaged using an X-ray laser
Ingår i Scientific Data, 2016
- DOI för Open data set of live cyanobacterial cells imaged using an X-ray laser
- Ladda ner fulltext (pdf) av Open data set of live cyanobacterial cells imaged using an X-ray laser
SHARP: a distributed GPU-based ptychographic solver
Ingår i Journal of applied crystallography, s. 1245-1252, 2016
Single-shot diffraction data from the Mimivirus particle using an X-ray free-electron laser
Ingår i Scientific Data, 2016
- DOI för Single-shot diffraction data from the Mimivirus particle using an X-ray free-electron laser
- Ladda ner fulltext (pdf) av Single-shot diffraction data from the Mimivirus particle using an X-ray free-electron laser
Ingår i Scientific Reports, 2016
- DOI för The infectious particle of insect-borne totivirus-like Omono River virus has raised ridges and lacks fibre complexes
- Ladda ner fulltext (pdf) av The infectious particle of insect-borne totivirus-like Omono River virus has raised ridges and lacks fibre complexes
The trickle before the torrent-diffraction data from X-ray lasers
Ingår i Scientific Data, 2016
- DOI för The trickle before the torrent-diffraction data from X-ray lasers
- Ladda ner fulltext (pdf) av The trickle before the torrent-diffraction data from X-ray lasers
Imaging single cells in a beam of live cyanobacteria with an X-ray laser
Ingår i Nature Communications, 2015
The linac coherent light source single particle imaging road map
Ingår i Structural Dynamics, 2015
Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser
Ingår i Physical Review Letters, 2015
- DOI för Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser
- Ladda ner fulltext (pdf) av Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser
Ingår i Journal of applied crystallography, s. 1118-1131, 2014
- DOI för Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data
- Ladda ner fulltext (pdf) av Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data