Neuropsykofarmakologi

Med fokus på psykoneurobiologi ägnar sig forskargruppen i huvudsak med forskning kring:
- Hur könshormoners molekylära mekanismer påverkar kvinnors beteende och psykiska hälsa. Genom tillämpning av genetiska, endokrina, farmakologiska, neurofysiologiska samt hjärnavbildande metoder och analyser ämnar vi att karaktärisera biomarkörer relaterade till könsspecifika sjukdomstillstånd och därigenom skapa förutsättningar som underlättar diagnos och behandling.
- Hur tidig exposition för stress och alkohol har effekter på hjärna och beteende undertonåren. Interaktioner mellan gener och miljö har studerats hos gnagare liksom i populationsbaserade mänskliga urval för att identifiera biomarkörer som påvisar ökad känslighet för alkoholanvändning och alkoholmissbruk.
Gruppmedlemmar
Publikationer
Ingår i Progress in Neuro-psychopharmacology and Biological Psychiatry, 2025
- DOI för White matter integrity upon progesterone antagonism in individuals with premenstrual dysphoric disorder: A randomized placebo-controlled diffusion tensor imaging study
- Ladda ner fulltext (pdf) av White matter integrity upon progesterone antagonism in individuals with premenstrual dysphoric disorder: A randomized placebo-controlled diffusion tensor imaging study
Ingår i Frontiers in Neuroendocrinology, 2025
- DOI för Progestagens and progesterone receptor modulation: Effects on the brain, mood, stress, and cognition in females
- Ladda ner fulltext (pdf) av Progestagens and progesterone receptor modulation: Effects on the brain, mood, stress, and cognition in females
Ingår i BMJ Open, 2025
- DOI för Emotion regulation-based internet-delivered cognitive behavioural therapy for premenstrual dysphoric disorder: study protocol for a randomised controlled trial in Sweden
- Ladda ner fulltext (pdf) av Emotion regulation-based internet-delivered cognitive behavioural therapy for premenstrual dysphoric disorder: study protocol for a randomised controlled trial in Sweden
The impact of pharmacotherapy for premenstrual dysphoric disorder on sleep
Ingår i Sleep Medicine Reviews, 2025
- DOI för The impact of pharmacotherapy for premenstrual dysphoric disorder on sleep
- Ladda ner fulltext (pdf) av The impact of pharmacotherapy for premenstrual dysphoric disorder on sleep
Aromatase, sex hormones and the young adult brain
2024
How sex and gender shape functional brain networks
Ingår i Science Advances, 2024
- DOI för How sex and gender shape functional brain networks
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Ingår i Molecular Autism, 2024
- DOI för Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
- Ladda ner fulltext (pdf) av Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
Ingår i Biology of Sex Differences, 2024
- DOI för Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
- Ladda ner fulltext (pdf) av Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
Ingår i Journal of Affective Disorders, s. 470-477, 2024
- DOI för Cortical morphology variations during the menstrual cycle in individuals with and without premenstrual dysphoric disorder
- Ladda ner fulltext (pdf) av Cortical morphology variations during the menstrual cycle in individuals with and without premenstrual dysphoric disorder
Electroencephalography findings in menstrually-related mood disorders: A critical review
Ingår i Frontiers in Neuroendocrinology, 2024
- DOI för Electroencephalography findings in menstrually-related mood disorders: A critical review
- Ladda ner fulltext (pdf) av Electroencephalography findings in menstrually-related mood disorders: A critical review
Ingår i Psychoneuroendocrinology, 2024
- DOI för White matter volume and treatment with selective progesterone receptor modulator in patients with premenstrual dysphoric disorder
- Ladda ner fulltext (pdf) av White matter volume and treatment with selective progesterone receptor modulator in patients with premenstrual dysphoric disorder
Ingår i BMC Psychiatry, 2024
- DOI för Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences
- Ladda ner fulltext (pdf) av Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences
2024
Mid-pregnancy allopregnanolone levels and trajectories of perinatal depressive symptoms
Ingår i Psychoneuroendocrinology, 2024
- DOI för Mid-pregnancy allopregnanolone levels and trajectories of perinatal depressive symptoms
- Ladda ner fulltext (pdf) av Mid-pregnancy allopregnanolone levels and trajectories of perinatal depressive symptoms
New Pharmacological Approaches to the Management of Premenstrual Dysphoric Disorder
Ingår i CNS Drugs, s. 371-379, 2023
- DOI för New Pharmacological Approaches to the Management of Premenstrual Dysphoric Disorder
- Ladda ner fulltext (pdf) av New Pharmacological Approaches to the Management of Premenstrual Dysphoric Disorder
Ingår i Translational Psychiatry, 2023
- DOI för Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids
- Ladda ner fulltext (pdf) av Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids
Editorial: Effects of hormonal contraceptives on the brain
Ingår i Frontiers in Endocrinology, 2023
- DOI för Editorial: Effects of hormonal contraceptives on the brain
- Ladda ner fulltext (pdf) av Editorial: Effects of hormonal contraceptives on the brain
Ingår i Comprehensive Psychiatry, 2023
- DOI för Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study
- Ladda ner fulltext (pdf) av Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study
2023
Levonorgestrel intrauterine device and depression: A Swedish register-based cohort study
Ingår i International Journal of Psychophysiology, 2023
- DOI för Levonorgestrel intrauterine device and depression: A Swedish register-based cohort study
- Ladda ner fulltext (pdf) av Levonorgestrel intrauterine device and depression: A Swedish register-based cohort study
Ingår i Translational Psychiatry, 2022
- DOI för Differential grey matter structure in women with premenstrual dysphoric disorder: evidence from brain morphometry and data-driven classification
- Ladda ner fulltext (pdf) av Differential grey matter structure in women with premenstrual dysphoric disorder: evidence from brain morphometry and data-driven classification
Ingår i European Neuropsychopharmacology, s. 35-43, 2022
- DOI för Grey matter morphology in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
- Ladda ner fulltext (pdf) av Grey matter morphology in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator.
Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder
Ingår i Scientific Reports, 2022
- DOI för Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder
- Ladda ner fulltext (pdf) av Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder
Exploring the relationship between early life adversity, telomere length and peripartum depression
2022
Ingår i Scientific Reports, 2021
- DOI för DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study
- Ladda ner fulltext (pdf) av DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study
DNA methylation in cord blood in association with prenatal depressive symptoms
Ingår i Clinical Epigenetics, 2021
- DOI för DNA methylation in cord blood in association with prenatal depressive symptoms
- Ladda ner fulltext (pdf) av DNA methylation in cord blood in association with prenatal depressive symptoms
Ingår i Frontiers in Neuroendocrinology, 2021
Ingår i Neuropsychopharmacology, s. 1460-1467, 2021
- DOI för Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator
- Ladda ner fulltext (pdf) av Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator
Ingår i American Journal of Psychiatry, s. 256-265, 2021
Neuroimaging the menstrual cycle: A multimodal systematic review
Ingår i Frontiers in neuroendocrinology (Print), 2021
- DOI för Neuroimaging the menstrual cycle: A multimodal systematic review
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Neuroimaging premenstrual dysphoric disorder: A systematic and critical review
Ingår i Frontiers in neuroendocrinology (Print), 2020
Ingår i Behavioural Brain Research, 2020
Ingår i Frontiers in neuroendocrinology (Print), 2020
Ingår i Psychoneuroendocrinology, s. 1-8, 2019
Early life stress and voluntary alcohol consumption in relation to Maoa methylation in male rats.
Ingår i Alcohol, s. 7-16, 2019
Ingår i European Child and Adolescent Psychiatry, s. 1329-1340, 2019
- DOI för VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths
- Ladda ner fulltext (pdf) av VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths
Ingår i Frontiers in Psychology, 2019
- DOI för Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age
- Ladda ner fulltext (pdf) av Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age
Ingår i ACS Chemical Neuroscience, s. 3132-3142, 2019
Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.
Ingår i Journal of neural transmission, s. 107-130, 2018
- DOI för Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.
- Ladda ner fulltext (pdf) av Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.
Platelet monoamine oxidase activity and interpersonal violence in male suicide attempters
Ingår i Psychiatry Research, s. 173-176, 2018
Ingår i Journal of neural transmission, s. 1601-1626, 2018
- DOI för Gene-environment interaction of monoamine oxidase A in relation to antisocial behaviour: current and future directions.
- Ladda ner fulltext (pdf) av Gene-environment interaction of monoamine oxidase A in relation to antisocial behaviour: current and future directions.
Ingår i Development and psychopathology (Print), s. 449-459, 2018
Ingår i Alcoholism, s. 508-519, 2018
Tracer kinetic analysis of [C-11] Cetrozole as a PET tracer for aromatase in the human brain
Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 71-72, 2017
Ingår i Child Psychiatry and Human Development, s. 584-596, 2017
- DOI för A Biopsychosocial Approach to Risk and Resilience on Behavior in Children Followed from Birth to Age 12
- Ladda ner fulltext (pdf) av A Biopsychosocial Approach to Risk and Resilience on Behavior in Children Followed from Birth to Age 12
Ingår i Molecular Neurobiology, s. 6225-6234, 2017
- DOI för Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans
- Ladda ner fulltext (pdf) av Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans
Ingår i European psychiatry, 2017
Ingår i Hormones and Behavior, s. 106-113, 2017
- DOI för Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway
- Ladda ner fulltext (pdf) av Allopregnanolone levels and depressive symptoms during pregnancy in relation to single nucleotide polymorphisms in the allopregnanolone synthesis pathway
Ingår i Brain Research, s. 36-45, 2017
- DOI för The expression of opioid genes in non-classical reward areas depends on early life conditions and ethanol intake
- Ladda ner fulltext (pdf) av The expression of opioid genes in non-classical reward areas depends on early life conditions and ethanol intake
Vgluts In The Mesocorticolimbic Brain Of Adolescent Outbred Rats Exposed To Alcohol And Nicotine
Ingår i Alcohol and Alcoholism, 2017