Barnonkologisk och neurologisk forskning
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Genom att öka förståelse för kliniska, biologiska, och psykosociala aspekter av barnneurologiska sjukdomar och barncancer, arbetar forskargruppen Barnonkologisk och neurologisk forskning på att förbättra livskvalitet för barn och ungdomar med dessa sjukdomar och deras familjer.
Bredden är stor på den forskning som sker inom vår forskargrupp, från experimentell forskning med molekylärbiologiska tekniker till beteendevetenskaplig forskning som syftar till att hjälpa barn och familjer att bättre klara den krävande behandlingen. Vi samarbetar både nationellt och internationellt med att leda och samverka i olika forskningsprojekt. Vi arbetar särskilt tätt ihop med forskargruppen Barnonkologisk klinisk och translationell forskning som vi har flera gemensamma projekt med.
Särskilda resurser vid Uppsala universitet
Protonstrålning
Skandionkliniken i Uppsala som startade 2015 är en nationell, och även nordisk, resurs som har medfört en viktig utökning av den barnonkologiska behandlingsarsenalen. Protonbehandling gör att strålfälten kan avgränsas med stor precision. Tillkomsten av Skandionkliniken ger även utökade möjligheter till strålbehandling i de lägre åldrarna, där man för närvarande är restriktiv på grund av risker för allvarliga sena komplikationer, framför allt i hjärnan.
Biobanker
Det finns två biobanker med koppling till Uppsala som är särskilt inriktad mot barnonkologi och barnneurologi: Nordisk biobank för barnleukemi (Frost huvudansvarig, Palle et al.) och Barntumörbanken (Ljungman klinisk ledare och ordförande för styrgruppen). Läs mer om både biobanker på Barncancerfondens webbsida.
Finansiärer
Vi vill rikta ett varmt tack till våra finansiärer, samverkanspartner, och alla patienter och deras familjer som möjliggör vårt forskningsarbete, bland annat Barncancerfonden, Gillbergska Stiftelsen, Lions Cancerforskningsfond Mellansverige Uppsala-Örebro, Mary Bevés Stiftelse, Insamlingsstiftelsen för Prader-Willi forskning och Region Uppsala.
Gruppmedlemmar
Publikationer
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Ingår i Radiography, 2026
- DOI för Children's experiences of coping with proton radiotherapy: A mixed-method study at a Swedish nationwide clinic
- Ladda ner fulltext (pdf) av Children's experiences of coping with proton radiotherapy: A mixed-method study at a Swedish nationwide clinic
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Ingår i Pediatric Neurology, s. 134-140, 2026
- DOI för The Lack of Broad Multidisciplinary Assessments in Children and Adolescents With Newly Diagnosed Idiopathic Intracranial Hypertension
- Ladda ner fulltext (pdf) av The Lack of Broad Multidisciplinary Assessments in Children and Adolescents With Newly Diagnosed Idiopathic Intracranial Hypertension
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Ingår i Acta Paediatrica, s. 697-705, 2026
- DOI för Overall Good Quality of Life Reported by Survivors of Childhood Hodgkin Lymphoma in Sweden and Finland
- Ladda ner fulltext (pdf) av Overall Good Quality of Life Reported by Survivors of Childhood Hodgkin Lymphoma in Sweden and Finland
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Ingår i Pediatric Blood & Cancer, 2026
- DOI för Early Toxicity in Childhood Acute Lymphoblastic Leukemia: A Comparison of NOPHO ALL2008 and ALLTogether Protocols in Sweden
- Ladda ner fulltext (pdf) av Early Toxicity in Childhood Acute Lymphoblastic Leukemia: A Comparison of NOPHO ALL2008 and ALLTogether Protocols in Sweden
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Ingår i JMIR Formative Research, 2026
- DOI för Process Evaluation of Interdisciplinary Experiences During the Development of a Serious Game About Radiotherapy for Children: Qualitative Interview Study
- Ladda ner fulltext (pdf) av Process Evaluation of Interdisciplinary Experiences During the Development of a Serious Game About Radiotherapy for Children: Qualitative Interview Study
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An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia
Ingår i Communications Medicine, 2026
- DOI för An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia
- Ladda ner fulltext (pdf) av An integrative molecular map of pediatric B-cell precursor acute lymphoblastic leukemia
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Ingår i Pediatric Blood & Cancer, 2026
- DOI för Infectious Complications During Early Treatment of Childhood Acute Lymphoblastic Leukemia-A Comparison Between the ALLTogether and NOPHO ALL-2008 Protocols
- Ladda ner fulltext (pdf) av Infectious Complications During Early Treatment of Childhood Acute Lymphoblastic Leukemia-A Comparison Between the ALLTogether and NOPHO ALL-2008 Protocols
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Ingår i Cancer Epidemiology, 2026
- DOI för Impact of treatment for childhood acute lymphoblastic leukemia on later education, paid labor, and sickness- or activity compensation: A registry study from Sweden
- Ladda ner fulltext (pdf) av Impact of treatment for childhood acute lymphoblastic leukemia on later education, paid labor, and sickness- or activity compensation: A registry study from Sweden
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Ingår i BMJ Open, 2026
- DOI för Cancer survival and its social determinants among children with a migrant background: systematic review protocol
- Ladda ner fulltext (pdf) av Cancer survival and its social determinants among children with a migrant background: systematic review protocol
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Ingår i Journal of Pediatric Nursing, s. 67-75, 2026
- DOI för Children's lived experiences of transitioning between hospital and home in paediatric oncology: A qualitative study
- Ladda ner fulltext (pdf) av Children's lived experiences of transitioning between hospital and home in paediatric oncology: A qualitative study
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Ingår i European Journal of Oncology Nursing, 2025
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Ingår i International Journal of Cancer, s. 1347-1357, 2025
- DOI för Educational outcomes school year nine in children treated for acute lymphoblastic leukemia: A nationwide registry‐based study from Sweden
- Ladda ner fulltext (pdf) av Educational outcomes school year nine in children treated for acute lymphoblastic leukemia: A nationwide registry‐based study from Sweden
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Ingår i Frontiers in Immunology, 2025
- DOI för The quantity and quality of B-cell immunity against SARS-CoV-2 in children with cancer and hematological diseases
- Ladda ner fulltext (pdf) av The quantity and quality of B-cell immunity against SARS-CoV-2 in children with cancer and hematological diseases
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Quality of life after treatment for childhood Hodgkin lymphoma in Sweden and Finland
2025
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Ingår i Acta Paediatrica, 2025
- DOI för Systematic follow‐ups were not associated with reduced acute ventriculoperitoneal shunt dysfunction in infancy
- Ladda ner fulltext (pdf) av Systematic follow‐ups were not associated with reduced acute ventriculoperitoneal shunt dysfunction in infancy
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2025
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Ingår i Studies in Health Technology and Informatics, s. 929-933, 2025
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Risk Factors for Traumatic Lumbar Puncture in Children With ALL
Ingår i Acta Paediatrica, s. 2713-2715, 2025
- DOI för Risk Factors for Traumatic Lumbar Puncture in Children With ALL
- Ladda ner fulltext (pdf) av Risk Factors for Traumatic Lumbar Puncture in Children With ALL
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Ingår i British Journal of Haematology, s. 1454-1463, 2025
- DOI för Characteristics and prognosis of paediatric normal karyotype acute myeloid leukaemia: A NOPHO-DBH AML study
- Ladda ner fulltext (pdf) av Characteristics and prognosis of paediatric normal karyotype acute myeloid leukaemia: A NOPHO-DBH AML study
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Ingår i Disability and Rehabilitation, s. 4467-4475, 2025
- DOI för Long-term outcome and rehabilitation needs after acquired brain injury in children and adolescents: an evaluation in a Swedish cohort
- Ladda ner fulltext (pdf) av Long-term outcome and rehabilitation needs after acquired brain injury in children and adolescents: an evaluation in a Swedish cohort
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School Nurses’ Experiences of the School-Based HPV Vaccination Program – A Decade Later
Ingår i Journal of School Nursing, 2025
- DOI för School Nurses’ Experiences of the School-Based HPV Vaccination Program – A Decade Later
- Ladda ner fulltext (pdf) av School Nurses’ Experiences of the School-Based HPV Vaccination Program – A Decade Later
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Ingår i Thrombosis Research, 2025
- DOI för Venous thromboembolism in children with Hodgkin lymphoma: A population-based study in Sweden, Finland, and Denmark
- Ladda ner fulltext (pdf) av Venous thromboembolism in children with Hodgkin lymphoma: A population-based study in Sweden, Finland, and Denmark
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Ingår i British Journal of Haematology, s. 1920-1929, 2025
- DOI för Early prediction of subsequent peg-asparaginase inactivation in acute lymphoblastic leukaemia patients-A NOPHO ALL2008 study
- Ladda ner fulltext (pdf) av Early prediction of subsequent peg-asparaginase inactivation in acute lymphoblastic leukaemia patients-A NOPHO ALL2008 study
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Ingår i JMIR Pediatrics and Parenting, 2025
- DOI för Perspectives on Swedish Regulations for Online Record Access Among Adolescents With Serious Health Issues and Their Parents: Mixed Methods Study
- Ladda ner fulltext (pdf) av Perspectives on Swedish Regulations for Online Record Access Among Adolescents With Serious Health Issues and Their Parents: Mixed Methods Study
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Ingår i BMC Health Services Research, 2025
- DOI för Pediatric oncology healthcare professionals’ attitudes to and awareness of regulations for minors’ and guardians’ online record access: A mixed-methods study in Sweden
- Ladda ner fulltext (pdf) av Pediatric oncology healthcare professionals’ attitudes to and awareness of regulations for minors’ and guardians’ online record access: A mixed-methods study in Sweden
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Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
Ingår i HemaSphere, 2025
- DOI för Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
- Ladda ner fulltext (pdf) av Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
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Ingår i Pediatric Blood & Cancer, 2024
- DOI för Educational and occupational outcomes in Swedish children treated for sarcomas: A nationwide registry-based study
- Ladda ner fulltext (pdf) av Educational and occupational outcomes in Swedish children treated for sarcomas: A nationwide registry-based study
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Radiotherapy-induced vascular cognitive impairment 20 years after childhood brain tumor
Ingår i Neuro-Oncology, s. 362-373, 2024
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Ingår i Journal of Clinical Oncology, s. 2174-2185, 2024
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Ingår i International Journal of Molecular Sciences, 2024
- DOI för Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation
- Ladda ner fulltext (pdf) av Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation
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Ingår i HemaSphere, 2024
- DOI för Parents' perception of treatment-related toxicity in children treated according to the NOPHO ALL2008 protocol for acute lymphoblastic leukemia
- Ladda ner fulltext (pdf) av Parents' perception of treatment-related toxicity in children treated according to the NOPHO ALL2008 protocol for acute lymphoblastic leukemia
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Ingår i Early Human Development, 2024
- DOI för Neonatal therapeutic hypothermia in a regional swedish cohort: Adherence to guidelines, transport and outcomes
- Ladda ner fulltext (pdf) av Neonatal therapeutic hypothermia in a regional swedish cohort: Adherence to guidelines, transport and outcomes
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Ingår i Pediatric Blood & Cancer, 2024
- DOI för Quality of life in children and adolescents after treatment for acute lymphoblastic leukemia according to the NOPHO ALL2008 protocol
- Ladda ner fulltext (pdf) av Quality of life in children and adolescents after treatment for acute lymphoblastic leukemia according to the NOPHO ALL2008 protocol
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Intensive care in children with non-Hodgkin lymphoma in Sweden
Ingår i Acta Paediatrica, s. 1974-1976, 2024
- DOI för Intensive care in children with non-Hodgkin lymphoma in Sweden
- Ladda ner fulltext (pdf) av Intensive care in children with non-Hodgkin lymphoma in Sweden
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Ingår i Acta Paediatrica, s. 2676-2678, 2024
- DOI för Haemostasis during early treatment of childhood acute lymphoblastic leukaemia with the ALLTogether protocol
- Ladda ner fulltext (pdf) av Haemostasis during early treatment of childhood acute lymphoblastic leukaemia with the ALLTogether protocol
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Ingår i British Journal of Haematology, s. 1450-1459, 2024
- DOI för Severe steroid-related neuropsychiatric symptoms during paediatric acute lymphoblastic leukaemia therapy-An observational Ponte di Legno Toxicity Working Group Study
- Ladda ner fulltext (pdf) av Severe steroid-related neuropsychiatric symptoms during paediatric acute lymphoblastic leukaemia therapy-An observational Ponte di Legno Toxicity Working Group Study
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Ingår i Acta Paediatrica, s. 2398-2405, 2024
- DOI för Unpredictable supplementation of vitamin D to infants in the neonatal intensive care unit: An experimental study
- Ladda ner fulltext (pdf) av Unpredictable supplementation of vitamin D to infants in the neonatal intensive care unit: An experimental study
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Ingår i Children & society, s. 228-244, 2024
- DOI för Exploring young people's experiences of race, gender and socioeconomic status in relation to everyday challenges: A focus group study
- Ladda ner fulltext (pdf) av Exploring young people's experiences of race, gender and socioeconomic status in relation to everyday challenges: A focus group study
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Ingår i Brain Injury, s. 151-159, 2024
- DOI för Further recommendations of the International Paediatric Brain Injury Society (IPBIS) for the post-acute rehabilitation of children with acquired brain injury
- Ladda ner fulltext (pdf) av Further recommendations of the International Paediatric Brain Injury Society (IPBIS) for the post-acute rehabilitation of children with acquired brain injury
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Ingår i Pediatric Blood & Cancer, 2024
- DOI för Symptomatic osteonecrosis in children treated for Hodgkin lymphoma: A population‐based study in Sweden, Finland, and Denmark
- Ladda ner fulltext (pdf) av Symptomatic osteonecrosis in children treated for Hodgkin lymphoma: A population‐based study in Sweden, Finland, and Denmark
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Radiological follow‐up of osteonecrosis lesions in children and adolescents with Hodgkin lymphoma
Ingår i British Journal of Haematology, s. 1460-1468, 2024
- DOI för Radiological follow‐up of osteonecrosis lesions in children and adolescents with Hodgkin lymphoma
- Ladda ner fulltext (pdf) av Radiological follow‐up of osteonecrosis lesions in children and adolescents with Hodgkin lymphoma
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Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
Ingår i Clinical Epigenetics, 2024
- DOI för Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
- Ladda ner fulltext (pdf) av Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
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Ingår i Haematologica, s. 2846-2853, 2024
- DOI för Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study
- Ladda ner fulltext (pdf) av Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study
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Ingår i Haematologica, s. 2873-2883, 2024
- DOI för Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol
- Ladda ner fulltext (pdf) av Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol
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Ingår i JBMR Plus, 2024
- DOI för Demographic and disease-related factors impact bone turnover and vitamin D in children with hemato-oncological diseases
- Ladda ner fulltext (pdf) av Demographic and disease-related factors impact bone turnover and vitamin D in children with hemato-oncological diseases
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Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening
Ingår i NAR Genomics and Bioinformatics, 2024
- DOI för Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening
- Ladda ner fulltext (pdf) av Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening
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Ingår i Acta Paediatrica, s. 742-752, 2023
- DOI för Predictive value of Bayley-III Motor Index for later motor difficulties in children born extremely preterm
- Ladda ner fulltext (pdf) av Predictive value of Bayley-III Motor Index for later motor difficulties in children born extremely preterm
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Childhood lymphoma treatment impacts educational outcomes: a registry study from Sweden
Ingår i Journal of cancer survivorship, s. 1072-1081, 2023
- DOI för Childhood lymphoma treatment impacts educational outcomes: a registry study from Sweden
- Ladda ner fulltext (pdf) av Childhood lymphoma treatment impacts educational outcomes: a registry study from Sweden
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Ingår i British Journal of Haematology, s. 384-392, 2023
- DOI för The prognostic impact of IKZF1 deletions and UKALL genetic classifiers in paediatric B-cell precursor acute lymphoblastic leukaemia treated according to NOPHO 2008 protocols
- Ladda ner fulltext (pdf) av The prognostic impact of IKZF1 deletions and UKALL genetic classifiers in paediatric B-cell precursor acute lymphoblastic leukaemia treated according to NOPHO 2008 protocols
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Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia
Ingår i British Journal of Haematology, s. 757-765, 2023
- DOI för Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia
- Ladda ner fulltext (pdf) av Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia

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