Pediatrisk inflammations- och metabolismforskning samt barnhälsa

Inom Gruppen för Pediatrisk Inflammationsforskning forskar vi på ett antal vanliga sjukdomar såsom astma och allergi, tarmsjukdomar, fr.a. coeliacisjukdomen men också på mindre vanliga sjukdomar såsom de reumatiska sjukdomarna. Samtliga dessa sjukdomar karakteriseras av inflammation.
Därför studeras inflammationsmarkörer och deras betydelse för att diagnostisera och övervaka sjukdom, det gäller t.ex. mätning av kväveoxid i utandad luft som vid astma kan användas både för diagnos och för att styra behandling. Sjukdomsmarkörer som ibland är rena inflammationsmarkörer studeras relativt tarmsjukdomar och reumatologiska sjukdomar. Vid dessa sjukdomstillstånd försöker vi också förbättra den kliniska karakteriseringen av patienterna. Vad gäller barnsjukdomar som är inflammatoriska sjukdomar samverkar vi i ”Centrum för pediatrisk inflammationsforskning”. Cystisk Fibros är en ovanlig sjukdom som bl.a. drabbar lungorna med segt slem samt svåra infektioner i luftvägarna. Sjukdomen orsakas av defekt funktion i kloridkanalen i celler och vi försöker hitta läkemedel som kan påverka detta. En ny metod för att diagnosticera sjukdomen är också under utveckling. Inom barnhälsovården har vi en rad olika projekt. Vi gör en uppföljning av specialbarnavårdscentralernas verksamhet. I projektet ”Barnhälsovård i förändring”, försöker vi effektivisera och optimera barnavårdscentralernas verksamhet. I ytterligare ett projekt utvärderas metoder för bedömning av språkutvecklingen hos barn. Den allmänpediatriska forskningsgruppen omfattar också forskning på nattväta och hur detta tillstånd behandlas samt på immunsystemets utveckling hos nyfödda barn.
Gruppmedlemmar
Publikationer
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Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 954-976, 2026
- DOI för Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines — 2024–2025 Revision: Part I — Guidelines on Intranasal Treatments
- Ladda ner fulltext (pdf) av Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines — 2024–2025 Revision: Part I — Guidelines on Intranasal Treatments
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Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 1947-1970, 2026
- DOI för Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines-2024-2025 Revision: Part II-Guidelines on Oral and Ocular Treatments
- Ladda ner fulltext (pdf) av Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines-2024-2025 Revision: Part II-Guidelines on Oral and Ocular Treatments
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Allergic sensitization in asthma and COPD in the NOVELTY study
Ingår i Respiratory Medicine, 2026
- DOI för Allergic sensitization in asthma and COPD in the NOVELTY study
- Ladda ner fulltext (pdf) av Allergic sensitization in asthma and COPD in the NOVELTY study
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Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2026
- DOI för APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans
- Ladda ner fulltext (pdf) av APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans
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Ingår i Clinical and Experimental Allergy, s. 176-179, 2026
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Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics
Ingår i Clinical and Translational Allergy, 2026
- DOI för Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics
- Ladda ner fulltext (pdf) av Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics
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2026
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Childen with enuresis - are they more constipated than others?
Ingår i Journal of Pediatric Urology, 2026
- DOI för Childen with enuresis - are they more constipated than others?
- Ladda ner fulltext (pdf) av Childen with enuresis - are they more constipated than others?
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Ingår i Pediatric Obesity, 2026
- DOI för Combining GLP-1 Receptor Agonists and Health-Behaviour and Lifestyle Therapy Yields Higher Adherence and Reduces Session Needs for Successful Weight Management in Adolescence: An Observational Real-World Single-Center Study
- Ladda ner fulltext (pdf) av Combining GLP-1 Receptor Agonists and Health-Behaviour and Lifestyle Therapy Yields Higher Adherence and Reduces Session Needs for Successful Weight Management in Adolescence: An Observational Real-World Single-Center Study
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Ingår i Diagnostic microbiology and infectious disease, 2026
- DOI för Cough plates as a non-invasive alternative for pathogen detection in paediatric community-acquired pneumonia
- Ladda ner fulltext (pdf) av Cough plates as a non-invasive alternative for pathogen detection in paediatric community-acquired pneumonia
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Ingår i Biomedicines, s. 694-694, 2026
- DOI för Disease-Causing Mechanisms and Therapeutic Targets in Infectious Diseases: Implications for Clinical Management and Public Health
- Ladda ner fulltext (pdf) av Disease-Causing Mechanisms and Therapeutic Targets in Infectious Diseases: Implications for Clinical Management and Public Health
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Ingår i Scientific Reports, 2026
- DOI för Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial
- Ladda ner fulltext (pdf) av Effect of dietary counseling and dietary fiber on tolerability during weight management with EMP16 and conventional orlistat: a single-blind randomized pilot trial
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Ingår i Frontiers in Pediatrics, 2026
- DOI för Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
- Ladda ner fulltext (pdf) av Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
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2026
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Glucose Intolerance in Children and Adolescents with Obesity
2026
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Ingår i Early Human Development, 2026
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Ingår i Acta Paediatrica, s. 1283-1289, 2026
- DOI för Improved Quality of Life in Children With Cystic Fibrosis Who Received Transmembrane Conductance Regulator Modulators
- Ladda ner fulltext (pdf) av Improved Quality of Life in Children With Cystic Fibrosis Who Received Transmembrane Conductance Regulator Modulators
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Ingår i Diabetes, obesity and metabolism, s. 4876-4883, 2026
- DOI för In vivo imaging of the innate immune system in the pancreas in new-onset and long-standing type 1 diabetes
- Ladda ner fulltext (pdf) av In vivo imaging of the innate immune system in the pancreas in new-onset and long-standing type 1 diabetes
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Infected total knee arthroplasty: could cotrimoxazole be the answer?
Ingår i European Journal of Clinical Microbiology and Infectious Diseases, s. 777-786, 2026
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Low ICU Admission and Excellent Outcomes in MIS-C: A Swedish Study From an Open Society
Ingår i Acta Paediatrica, s. 335-344, 2026
- DOI för Low ICU Admission and Excellent Outcomes in MIS-C: A Swedish Study From an Open Society
- Ladda ner fulltext (pdf) av Low ICU Admission and Excellent Outcomes in MIS-C: A Swedish Study From an Open Society
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Ingår i Scandinavian journal of urology, s. 8-14, 2026
- DOI för Lower urinary tract symptoms in adults treated for vesico-ureteral reflux in childhood, compared to healthy controls
- Ladda ner fulltext (pdf) av Lower urinary tract symptoms in adults treated for vesico-ureteral reflux in childhood, compared to healthy controls
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Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 427-453, 2026
- DOI för Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms
- Ladda ner fulltext (pdf) av Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI 2024-2025 Guidelines: From Evidence-to-Decision Frameworks to Digitalised Shared Decision-Making Algorithms
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Ingår i Physiological Reports, 2026
- DOI för Real-life application of respiratory oscillometry in pediatric asthma outpatient care: Feasibility and methodological aspects
- Ladda ner fulltext (pdf) av Real-life application of respiratory oscillometry in pediatric asthma outpatient care: Feasibility and methodological aspects
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Ingår i Clinical and Translational Allergy, 2026
- DOI för Serum and Nasal Lavage Fluid Eosinophil-Derived Neurotoxin Levels in Clinically Defined Asthma Phenotypes
- Ladda ner fulltext (pdf) av Serum and Nasal Lavage Fluid Eosinophil-Derived Neurotoxin Levels in Clinically Defined Asthma Phenotypes
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Ingår i Pediatric Rheumatology, 2026
- DOI för Serum bile salt-stimulated lipase levels associates with systemic inflammation and declines with effect of treatment in juvenile idiopathic arthritis
- Ladda ner fulltext (pdf) av Serum bile salt-stimulated lipase levels associates with systemic inflammation and declines with effect of treatment in juvenile idiopathic arthritis
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What is the treatment pattern of juvenile systemic sclerosis?: Results from an international cohort
Ingår i Journal of Scleroderma and Related Disorders, 2026
- DOI för What is the treatment pattern of juvenile systemic sclerosis?: Results from an international cohort
- Ladda ner fulltext (pdf) av What is the treatment pattern of juvenile systemic sclerosis?: Results from an international cohort
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Ingår i Clinical Pharmacology in Drug Development, s. 304-310, 2025
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Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK-air Study
Ingår i Clinical and Experimental Allergy, s. 226-238, 2025
- DOI för Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK-air Study
- Ladda ner fulltext (pdf) av Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK-air Study
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Adolescent males' consultations with GPs: Exploring GP's consultation techniques.: A study plan.
2025
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Age at diagnosis as a prognostic factor in selected categories of juvenile idiopathic arthritis
Ingår i RMD Open, 2025
- DOI för Age at diagnosis as a prognostic factor in selected categories of juvenile idiopathic arthritis
- Ladda ner fulltext (pdf) av Age at diagnosis as a prognostic factor in selected categories of juvenile idiopathic arthritis
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Allergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air Users
Ingår i Journal of investigational allergology & clinical immunology, s. 373-383, 2025
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Alterations of the pancreas in type 1 diabetes: from prior to diagnosis to long-standing disease
Ingår i Endocrine, s. 140-148, 2025
- DOI för Alterations of the pancreas in type 1 diabetes: from prior to diagnosis to long-standing disease
- Ladda ner fulltext (pdf) av Alterations of the pancreas in type 1 diabetes: from prior to diagnosis to long-standing disease
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Ingår i Pediatric Allergy and Immunology, 2025
- DOI för Asthma diagnosis is not associated with reduced beta-cell function in children and adolescents with obesity
- Ladda ner fulltext (pdf) av Asthma diagnosis is not associated with reduced beta-cell function in children and adolescents with obesity
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Ingår i Acta Médica Portuguesa, s. 208-216, 2025
- DOI för Automated Adjustment of the Fraction of Inspired Oxygen (FiO2) and the Time Spent in Normoxemia in Preterm Infants: [O Ajuste Automático da Fração Inspirada de Oxigénio (FiO2) e o Tempo em Normoxémia em Recém-Nascidos Prematuros]
- Ladda ner fulltext (pdf) av Automated Adjustment of the Fraction of Inspired Oxygen (FiO2) and the Time Spent in Normoxemia in Preterm Infants: [O Ajuste Automático da Fração Inspirada de Oxigénio (FiO2) e o Tempo em Normoxémia em Recém-Nascidos Prematuros]
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Ingår i Cardiovascular Diabetology, 2025
- DOI för Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
- Ladda ner fulltext (pdf) av Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
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Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 3319-3330, 2025
- DOI för Comparison of Allergic Rhinitis Treatments on Patient Satisfaction: A MASK-air and EAACI Methodological Committee Report
- Ladda ner fulltext (pdf) av Comparison of Allergic Rhinitis Treatments on Patient Satisfaction: A MASK-air and EAACI Methodological Committee Report
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Ingår i Frontiers in Pharmacology, 2025
- DOI för Curcumin: biochemistry, pharmacology, advanced drug delivery systems, and its epigenetic role in combating cancer
- Ladda ner fulltext (pdf) av Curcumin: biochemistry, pharmacology, advanced drug delivery systems, and its epigenetic role in combating cancer
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Ingår i Rheumatology, s. 2143-2152, 2025
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Ingår i Scientific Reports, 2025
- DOI för Development of a 3D cephalometric index to grade severity of dentofacial deformity in patients with juvenile idiopathic arthritis
- Ladda ner fulltext (pdf) av Development of a 3D cephalometric index to grade severity of dentofacial deformity in patients with juvenile idiopathic arthritis
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Ingår i Journal of Urology, s. 117-117, 2025
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Evaluation of BMI Growth Charts for Children Living with Severe Obesity
Ingår i CHILDHOOD OBESITY, s. 629-639, 2025
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Ingår i Journal of Nutritional Science, 2025
- DOI för Exploring nutritional risks of the specific carbohydrate diet: food and nutrient intake in children with juvenile idiopathic arthritis
- Ladda ner fulltext (pdf) av Exploring nutritional risks of the specific carbohydrate diet: food and nutrient intake in children with juvenile idiopathic arthritis
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Ingår i ACR Open Rheumatology, 2025
- DOI för HLA-B27 has wide clinical impact on juvenile idiopathic arthritis - Eighteen years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis Cohort
- Ladda ner fulltext (pdf) av HLA-B27 has wide clinical impact on juvenile idiopathic arthritis - Eighteen years of follow-up in the population-based Nordic Juvenile Idiopathic Arthritis Cohort
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2025
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Ingår i Scientific Reports, 2025
- DOI för Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
- Ladda ner fulltext (pdf) av Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
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Ingår i Pediatric Pulmonology, 2025
- DOI för Nasal Nitric Oxide Measurements During Tidal Breathing: A Device Comparison Study in Ciliary Disease.
- Ladda ner fulltext (pdf) av Nasal Nitric Oxide Measurements During Tidal Breathing: A Device Comparison Study in Ciliary Disease.
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Ingår i Pediatric Research, s. 182-187, 2025
- DOI för Obesity-related subclinical hypothyroidism in childhood: Elevated triglycerides but not basal metabolic rate
- Ladda ner fulltext (pdf) av Obesity-related subclinical hypothyroidism in childhood: Elevated triglycerides but not basal metabolic rate
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Ingår i Clinical Rheumatology, s. 2031-2041, 2025
- DOI för One-year follow-up of a short specific carbohydrate diet intervention in children with juvenile idiopathic arthritis: a retrospectively controlled study with focus on medical burden
- Ladda ner fulltext (pdf) av One-year follow-up of a short specific carbohydrate diet intervention in children with juvenile idiopathic arthritis: a retrospectively controlled study with focus on medical burden
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Ingår i BMC Primary Care, 2025
- DOI för Opportunities and difficulties with providing child healthcare through team-based visits in child healthcare services: a focus group study
- Ladda ner fulltext (pdf) av Opportunities and difficulties with providing child healthcare through team-based visits in child healthcare services: a focus group study
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Ingår i Child Protection and Practice, 2025
- DOI för Parents’ views of the acceptability and efficacy of the Safe Environment for Every Kid model in the Swedish child health services
- Ladda ner fulltext (pdf) av Parents’ views of the acceptability and efficacy of the Safe Environment for Every Kid model in the Swedish child health services