Publiceringar relaterade till Plattformen för preklinisk PET-MRI

Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts

Mortensen, Anja; Berglund, Hanna; Jha, Preeti; Stenman, Adam et al.

Ingår i Molecular Cancer Therapeutics, s. 753-762, 2025

• DOI för Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Ingår i Intensive Care Medicine Experimental, 2025

• DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Spiegelberg, Diana; Hwang, Le-Ann; Pua, Khian Hong; Kumar, Sashwini Chandra et al.

Ingår i Scientific Reports, 2025

• DOI för Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools
• Ladda ner fulltext (pdf) av Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
• Ladda ner fulltext (pdf) av Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Puuvuori, Emmi; Shen, Yunbing; Hulsart-Billström, Gry; Mitran, Bogdan et al.

Ingår i Journal of Nuclear Medicine, s. 294-299, 2024

• DOI för Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

PET imaging of GABA_A receptors in pancreatic islets by [¹¹C]flumazenil

Maloum-Rami, Faïza; Cheung, Pierre; Antoni, Gunnar; Jin, Zhe et al.

Ingår i EJNMMI Research, 2024

• DOI för PET imaging of GABA_A receptors in pancreatic islets by [¹¹C]flumazenil
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Radiation dosimetry of para-chloro-2-[¹⁸F]fluoroethyl-etomidate: a PET tracer for adrenocortical imaging

Silins, Isabella; Moreno, Adrian; Wall, Anders; Aigbirhio, Franklin et al.

Ingår i EJNMMI Research, 2024

• DOI för Radiation dosimetry of para-chloro-2-[¹⁸F]fluoroethyl-etomidate: a PET tracer for adrenocortical imaging
• Ladda ner fulltext (pdf) av Radiation dosimetry of para-chloro-2-[¹⁸F]fluoroethyl-etomidate: a PET tracer for adrenocortical imaging

Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

Velikyan, Irina; Bossart, Martin; Haack, Torsten; Laitinen, Iina et al.

Ingår i Pharmaceuticals, 2023

• DOI för Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences
• Ladda ner fulltext (pdf) av Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity

Geissel, Felix J.; Platania, Varvara; De Berardinis, Niccoló; Skjöldebrand, Charlotte et al.

Ingår i Advanced Materials Interfaces, 2023

• DOI för Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity
• Ladda ner fulltext (pdf) av Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity

PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Ingår i Journal of Nuclear Medicine, s. 423-429, 2023

• DOI för PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

Ingår i NeuroImage, 2023

• DOI för Synaptic density in aging mice measured by [18F]SynVesT-1 PET
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E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations

Wall, Anders; Roslin, Sara; Borg, Beatrice; McDermott, Simon et al.

Ingår i Pharmaceuticals, 2022

• DOI för E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations
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Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

Wechalekar, Ashutosh; Antoni, Gunnar; Al Azzam, Wasfi; Bergstrom, Mats et al.

Ingår i BMC Cardiovascular Disorders, 2022

• DOI för Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study
• Ladda ner fulltext (pdf) av Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase

Estrada, Sergio; Elgland, Mathias; Selvaraju, Ram Kumar; Mani, Kevin et al.

Ingår i Nuclear Medicine and Biology, s. 62-71, 2022

• DOI för Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase
• Ladda ner fulltext (pdf) av Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase

¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Nordeman, Patrik; Jayendra, Z. P.; Briard, E.; Li, Su-Chen et al.

Ingår i European Journal of Pharmaceutical Sciences, 2021

• DOI för ¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Rokka, Johanna; Nordeman, Patrik; Bergman, Sara; Eriksson, Jonas

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 447-455, 2021

• DOI för A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media
• Ladda ner fulltext (pdf) av A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Ingår i Scientific Reports, 2021

• DOI för Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
• Ladda ner fulltext (pdf) av Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Ingår i Diabetes, s. 966-975, 2021

• DOI för Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

News ways of understanding the complex biology of diabetes using PET

Eriksson, Olof; Långström, Bengt; Antoni, Gunnar

Ingår i Nuclear Medicine and Biology, s. 65-71, 2021

• DOI för News ways of understanding the complex biology of diabetes using PET

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Ingår i Biomedicines, 2021

• DOI för PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs
• Ladda ner fulltext (pdf) av PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Ingår i Nuclear Medicine and Biology, s. 54-62, 2021

• DOI för Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1
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Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients – A PET/MR study

Marklund, Niklas; Vedung, Fredrik; Lubberink, Mark; Tegner, Yelverton et al.

Ingår i NeuroImage, 2021

• DOI för Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients – A PET/MR study
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Theranostic Approach in Breast Cancer A Treasured Tailor for Future Oncology

Jokar, Narges; Velikyan, Irina; Ahmadzadehfar, Hojjat; Rekabpour, Seyed Javad et al.

Ingår i Clinical Nuclear Medicine, 2021

• DOI för Theranostic Approach in Breast Cancer A Treasured Tailor for Future Oncology

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Syvänen, Stina; Fang, Xiaotian T.; Faresjö, Rebecca; Rokka, Johanna et al.

Ingår i ACS Chemical Neuroscience, s. 4460-4468, 2020

• DOI för Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain
• Ladda ner fulltext (pdf) av Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Phosphodiesterase 10A levels are related to striatal function in schizophrenia: a combined positron emission tomography and functional magnetic resonance imaging study

Persson, Jonas; Szalisznyo, Krisztina; Antoni, Gunnar; Wall, Anders et al.

Ingår i European Archives of Psychiatry and Clinical Neuroscience, s. 451-459, 2020

• DOI för Phosphodiesterase 10A levels are related to striatal function in schizophrenia: a combined positron emission tomography and functional magnetic resonance imaging study
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Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.

Jonasson, My; Nordeman, Patrik; Eriksson, Jonas; Wilking, Helena et al.

Ingår i Journal of Neuroscience Research, s. 2208-2218, 2020

• DOI för Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.
• Ladda ner fulltext (pdf) av Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.

High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar et al.

Ingår i NeuroImage, s. 881-888, 2019

• DOI för High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Rokka, Johanna; Schlein, Eva; Eriksson, Jonas

Ingår i EJNMMI Radiopharmacy and Chemistry, 2019

• DOI för Improved synthesis of SV2A targeting radiotracer [11C]UCB-J
• Ladda ner fulltext (pdf) av Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

Heurling, Kerstin; Ashton, Nicholas J; Leuzy, Antoine; Zimmer, Eduardo R et al.

Ingår i Molecular and Cellular Neuroscience, s. 34-42, 2019

• DOI för Synaptic vesicle protein 2A as a potential biomarker in synaptopathies
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Synthesis and initial preclinical evaluation of the CRTH2 antagonist [C-11] MK-7246

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Journal of Labelled Compounds and Pharmaceuticals, 2019

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Nuclear Medicine and Biology, s. 1-10, 2019

• DOI för Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass
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Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

Olsen, Malin; Aguilar, Ximena; Sehlin, Dag; Fang, Xiaotian T. et al.

Ingår i Molecular Imaging and Biology, s. 605-614, 2018

• DOI för Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease
• Ladda ner fulltext (pdf) av Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

In Vivo Visualization of beta-Cells by Targeting of GPR44

Eriksson, Olof; Johnström, Peter; Cselenyi, Zsolt; Jahan, Mahabuba et al.

Ingår i Diabetes, s. 182-192, 2018

• DOI för In Vivo Visualization of beta-Cells by Targeting of GPR44

Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept

Hulsart Billström, Gry; Selvaraju, Ramkumar; Estrada, Sergio; Lubberink, Mark et al.

Ingår i Journal of Controlled Release, s. 178-186, 2018

• DOI för Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept
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Phase 0, Including Microdosing Approaches: Applying the Three Rs and Increasing the Efficiency of Human Drug Development

Burt, Tal; Vuong, Le Thuy; Baker, Elizabeth; Young, Graeme C. et al.

Ingår i ATLA (Alternatives to Laboratory Animals), s. 335-346, 2018

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Ingår i Theranostics, s. 4462-4476, 2018

• DOI för Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
• Ladda ner fulltext (pdf) av Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan, Mahabuba; Johnström, Peter; Selvaraju, Ramkumar; Svedberg, Marie et al.

Ingår i EJNMMI Research, 2018

• DOI för The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.
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Blood Flow Quantitation by Positron Emission Tomography During Selective Antegrade Cerebral Perfusion

Tovedal, Thomas; Lubberink, Mark; Morell, Arvid; Estrada, Sergio et al.

Ingår i Annals of Thoracic Surgery, s. 610-616, 2017

• DOI för Blood Flow Quantitation by Positron Emission Tomography During Selective Antegrade Cerebral Perfusion

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting

Fang, Xiaotian T.; Eriksson, Jonas; Antoni, Gunnar; Yngve, Ulrika et al.

Ingår i Neuropharmacology, s. 293-300, 2017

• DOI för Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting

Palladium-mediated C-11-carbonylations using aryl halides and cyanamide

Nordeman, Patrik; Chow, Shiao Y.; Odell, A. F.; Antoni, Gunnar et al.

Ingår i Organic and biomolecular chemistry, s. 4875-4881, 2017

• DOI för Palladium-mediated C-11-carbonylations using aryl halides and cyanamide

Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Eriksson, Olof; Rosenström, Ulrika; Selvaraju, Ram Kumar; Eriksson, Barbro et al.

Ingår i Acta Diabetologica, s. 1039-1045, 2017

• DOI för Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4
• Ladda ner fulltext (pdf) av Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

C-11 and F-18 Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates

Nordeman, Patrik; Johansson, Leif B. G.; Back, Marcus; Estrada, Sergio et al.

Ingår i ACS Medicinal Chemistry Letters, s. 368-373, 2016

• DOI för C-11 and F-18 Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates

[C-11]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A

Estrada, Sergio; Lubberink, Mark; Thibblin, Alf; Sprycha, Margareta et al.

Ingår i Nuclear Medicine and Biology, s. 325-332, 2016

• DOI för [C-11]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

Haylock, Anna-Karin; Spiegelberg, Diana; Mortensen, Anja C.; Selvaraju, Ram K. et al.

Ingår i International journal of oncology, s. 461-470, 2016

• DOI för Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma
• Ladda ner fulltext (pdf) av Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Honarvar, Hadis; Westerlund, Kristina; Altai, Mohamed; Sandström, Mattias et al.

Ingår i Theranostics, s. 93-103, 2016

• DOI för Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors
• Ladda ner fulltext (pdf) av Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Feasibility of affibody-based bioorthogonal chemistry-mediated radionuclide pretargeting

Altai, Mohamed; Perols, Anna; Tsourma, Maria; Mitran, Bogdan et al.

Ingår i Journal of Nuclear Medicine, s. 431-436, 2016

• DOI för Feasibility of affibody-based bioorthogonal chemistry-mediated radionuclide pretargeting

Ga-68/PET imaging and quantification of fibrosis using peptide-based tracers

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof; Antoni, Gunnar

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2016

Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.

Spiegelberg, Diana; Mortensen, Anja C; Selvaraju, Ram K; Eriksson, Olof et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 974-982, 2016

• DOI för Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.
• Ladda ner fulltext (pdf) av Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.

Tracer kinetic analysis of (S)-18F-THK5117 as a PET tracer for assessing tau pathology.

Jonasson, My; Wall, Anders; Chiotis, Konstantinos; Saint-Aubert, Laure et al.

Ingår i Journal of Nuclear Medicine, s. 574-581, 2016

• DOI för Tracer kinetic analysis of (S)-18F-THK5117 as a PET tracer for assessing tau pathology.

ADAPT, a novel scaffold protein-based probe for radionuclide imaging of molecular targets that are expressed in disseminated cancers

Garousi, Javad; Lindbo, Sarah; Nilvebrant, Johan; Åstrand, Mikael et al.

Ingår i Cancer Research, s. 4364-4371, 2015

• DOI för ADAPT, a novel scaffold protein-based probe for radionuclide imaging of molecular targets that are expressed in disseminated cancers