Våra aktuella publiceringar
Här tar du del av våra publicerade artiklar inom Theranostics. Välkommen att kontakta oss för ytterligare information om våra resultat.
Ingår i EJNMMI Radiopharmacy and Chemistry, 2025
- DOI för Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry?
- Ladda ner fulltext (pdf) av Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry?
Ingår i EJNMMI Research, 2025
- DOI för First-in-human experience with GRPR antagonist [68Ga]Ga-NOTA-PEG2-RM26 in prostate and breast cancer patients using PET/CT
- Ladda ner fulltext (pdf) av First-in-human experience with GRPR antagonist [68Ga]Ga-NOTA-PEG2-RM26 in prostate and breast cancer patients using PET/CT
Ingår i EJNMMI Radiopharmacy and Chemistry, 2025
- DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [18F]MeTz-PEG2-RM26 for positron emission tomography
- Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [18F]MeTz-PEG2-RM26 for positron emission tomography
Ingår i ACS Pharmacology & Translational Science, s. 3228-3240, 2024
- DOI för Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
- Ladda ner fulltext (pdf) av Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
Ingår i Molecules, 2024
- DOI för Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
- Ladda ner fulltext (pdf) av Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
Ingår i Molecular Pharmaceutics, s. 1919-1932, 2024
Ingår i EJNMMI Radiopharmacy and Chemistry, 2024
- DOI för Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
- Ladda ner fulltext (pdf) av Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
2024
Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4038-4048, 2024
- DOI för Evaluation of a novel 177Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
- Ladda ner fulltext (pdf) av Evaluation of a novel 177Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
Ingår i ACS Omega, s. 36122-36133, 2024
- DOI för Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
- Ladda ner fulltext (pdf) av Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
Ingår i Pharmaceutics, 2024
- DOI för GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
- Ladda ner fulltext (pdf) av GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
Ingår i Journal of Controlled Release, s. 468-478, 2024
- DOI för Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
- Ladda ner fulltext (pdf) av Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
Ingår i International Journal of Molecular Sciences, 2024
- DOI för Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m
- Ladda ner fulltext (pdf) av Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m
Ingår i Advanced Science, 2024
- DOI för Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy
- Ladda ner fulltext (pdf) av Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy
Ingår i Nanoscale, s. 17893-17907, 2024
- DOI för Laser-synthesized plasmonic HfN-based nanoparticles as a novel multifunctional agent for photothermal therapy
- Ladda ner fulltext (pdf) av Laser-synthesized plasmonic HfN-based nanoparticles as a novel multifunctional agent for photothermal therapy
Modification of contact lenses via metal-organic frameworks for glaucoma treatment
Ingår i Aggregate, 2024
- DOI för Modification of contact lenses via metal-organic frameworks for glaucoma treatment
- Ladda ner fulltext (pdf) av Modification of contact lenses via metal-organic frameworks for glaucoma treatment
MPS blockade with liposomes controls pharmacokinetics of nanoparticles in a size-dependent manner
Ingår i Biomedical Materials, 2024
- DOI för MPS blockade with liposomes controls pharmacokinetics of nanoparticles in a size-dependent manner
- Ladda ner fulltext (pdf) av MPS blockade with liposomes controls pharmacokinetics of nanoparticles in a size-dependent manner
Ingår i Cancers, 2024
- DOI för Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [99mTc]Tc(CO)3-(HE)3-Ec1 for Visualization of EpCAM-Expressing Lung Cancer
- Ladda ner fulltext (pdf) av Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [99mTc]Tc(CO)3-(HE)3-Ec1 for Visualization of EpCAM-Expressing Lung Cancer
Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
Ingår i International Journal of Molecular Sciences, 2024
- DOI för Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
- Ladda ner fulltext (pdf) av Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
Ingår i EJNMMI Radiopharmacy and Chemistry, 2024
- DOI för Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology
- Ladda ner fulltext (pdf) av Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology
Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery
Ingår i Perspectives, 2024
- DOI för Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery
- Ladda ner fulltext (pdf) av Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery
Ingår i ACS Pharmacology & Translational Science, s. 1595-1611, 2024
- DOI för Shorter Peptide Nucleic Acid Probes Improve Affibody-Mediated Peptide Nucleic Acid-Based Pretargeting
- Ladda ner fulltext (pdf) av Shorter Peptide Nucleic Acid Probes Improve Affibody-Mediated Peptide Nucleic Acid-Based Pretargeting
Ingår i ACS Pharmacology & Translational Science, s. 1457-1473, 2024
Ingår i ACS Omega, s. 18608-18616, 2024
- DOI för Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
- Ladda ner fulltext (pdf) av Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
Ingår i Frontiers in Oncology, 2023
- DOI för 177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
- Ladda ner fulltext (pdf) av 177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
Ingår i American Journal of Nuclear Medicine and Molecular Imaging, s. 107-+, 2023
Comparison of HER2-targeted affibody conjugates loaded with auristatin-and maytansine-derived drugs
Ingår i Journal of Controlled Release, s. 515-527, 2023
Ingår i Journal of Controlled Release, s. 185-195, 2023
Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs
2023
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
- Ladda ner fulltext (pdf) av Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
Ingår i Cancers, 2023
- DOI för Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
- Ladda ner fulltext (pdf) av Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
Ingår i Cancers, 2023
- DOI för Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
- Ladda ner fulltext (pdf) av Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Preclinical Evaluation of a Novel High-Affinity Radioligand [99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
- Ladda ner fulltext (pdf) av Preclinical Evaluation of a Novel High-Affinity Radioligand [99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
Preclinical evaluation of novel therapeutical GRPR-targeting antagonists labeled with 111In
2023
Ingår i Cancers, 2023
- DOI för Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
- Ladda ner fulltext (pdf) av Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
Ingår i International Journal of Molecular Sciences, 2023
- DOI för Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
- Ladda ner fulltext (pdf) av Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
Ingår i Diagnostics, 2023
- DOI för The GRPR Antagonist [99mTc]Tc-maSSS-PEG2-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity
- Ladda ner fulltext (pdf) av The GRPR Antagonist [99mTc]Tc-maSSS-PEG2-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity
Ingår i Oncology Letters, 2023
- DOI för Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125
- Ladda ner fulltext (pdf) av Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125
Ingår i Pharmaceutics, 2022
- DOI för Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis
- Ladda ner fulltext (pdf) av Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis
Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
Ingår i Pharmaceutics, 2022
- DOI för Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
- Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
Ingår i International Journal of Molecular Sciences, 2022
- DOI för Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
- Ladda ner fulltext (pdf) av Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
Ingår i Pharmaceutics, 2022
- DOI för Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2
- Ladda ner fulltext (pdf) av Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2
Ingår i Pharmaceutics, 2022
- DOI för Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule 188Re-ZHER2:41071
- Ladda ner fulltext (pdf) av Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule 188Re-ZHER2:41071
In vitro characterization of affibody molecules intended for therapy of EGFR-expressing cancer
2022
PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
Ingår i EJNMMI Research, 2022
- DOI för PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
- Ladda ner fulltext (pdf) av PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
Ingår i Journal of Nuclear Medicine, s. 528-535, 2022
Ingår i Pharmaceutics, 2022
- DOI för Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT
- Ladda ner fulltext (pdf) av Preclinical Evaluation of a New Format of Ga-68- and In-111-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT
Ingår i Biomedicines, 2022
- DOI för Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
- Ladda ner fulltext (pdf) av Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer
Ingår i Biomedicines, 2022
- DOI för The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer
- Ladda ner fulltext (pdf) av The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer
A method of drug delivery to tumors based on rapidly biodegradable drug-loaded containers
Ingår i APPLIED MATERIALS TODAY, 2021