Våra aktuella publiceringar

A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Olaniran Håkansson, Esther; Zelepukin, Ivan V.; Obeid, Karim; Bitzios, Athanasios et al.

Ingår i EJNMMI Research, 2025

• DOI för A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression
• Ladda ner fulltext (pdf) av A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Designed Ankyrin Repeat Protein-Mediated Peptide Nucleic Acid-Based Pretargeting: A Proof-of-Principle Study

Oroujeni, Maryam; Westerlund, Kristina; Papalanis, Eleftherios; van Deventer, Alexander et al.

Ingår i Journal of Nuclear Medicine, s. 1105-1111, 2025

• DOI för Designed Ankyrin Repeat Protein-Mediated Peptide Nucleic Acid-Based Pretargeting: A Proof-of-Principle Study

Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?

Kanellopoulos, Panagiotis; Yu, Quanyi; Abouzayed, Abouzayed; Bezverkhniaia, Ekaterina et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?
• Ladda ner fulltext (pdf) av Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?

First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT

Bjareback, Annie; Jonmarker, Olof; Tzortzakakis, Antonios; Jussing, Emma et al.

Ingår i EJNMMI Research, 2025

• DOI för First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT
• Ladda ner fulltext (pdf) av First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT

Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules

Tolmachev, Vladimir M.; Papalanis, Eleftherios; Bezverkhniaia, Ekaterina A.; Rosly, Alia Hani et al.

Ingår i ACS Pharmacology & Translational Science, s. 706-717, 2025

• DOI för Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules
• Ladda ner fulltext (pdf) av Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules

Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran Håkansson, Esther et al.

Ingår i Neuroscience Letters, 2025

• DOI för Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures
• Ladda ner fulltext (pdf) av Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures

Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir M. et al.

Ingår i European Journal of Pharmaceutical Sciences, 2025

• DOI för Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics
• Ladda ner fulltext (pdf) av Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Phase I Clinical Study with the GRPR-Antagonist [^99mTc]Tc-DB8 for SPECT Imaging of Prostate Cancer: Does the Injected Peptide Mass Make a Difference?

Orlova, Anna; Rybina, Anastasia; Medvedeva, Anna; Zelchan, Roman et al.

Ingår i Pharmaceutics, 2025

• DOI för Phase I Clinical Study with the GRPR-Antagonist [^99mTc]Tc-DB8 for SPECT Imaging of Prostate Cancer: Does the Injected Peptide Mass Make a Difference?
• Ladda ner fulltext (pdf) av Phase I Clinical Study with the GRPR-Antagonist [^99mTc]Tc-DB8 for SPECT Imaging of Prostate Cancer: Does the Injected Peptide Mass Make a Difference?

Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Rosenström, Ulrika; Tolmachev, Vladimir M. et al.

Ingår i ACS Pharmacology & Translational Science, s. 3600-3612, 2025

• DOI för Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m
• Ladda ner fulltext (pdf) av Reduction of negative charge in mercaptoacetyl-based chelators influences the biodistribution of prostate-specific membrane antigen-targeting pseudopeptides labeled with technetium-99m

RM2 and DB15 analogues bearing [¹⁷⁷Lu]Lu-DOTAGA via different linkers, as radiotherapeutics: a head-to-head comparative study

Kanellopoulos, Panagiotis; Bitzios, Athanasios; Zelepukin, Ivan; Bezverkhniaia, Ekaterina et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för RM2 and DB15 analogues bearing [¹⁷⁷Lu]Lu-DOTAGA via different linkers, as radiotherapeutics: a head-to-head comparative study
• Ladda ner fulltext (pdf) av RM2 and DB15 analogues bearing [¹⁷⁷Lu]Lu-DOTAGA via different linkers, as radiotherapeutics: a head-to-head comparative study

Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [^99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study

Medvedeva, Anna; Chernov, Vladimir; Larkina, Maria; Rybina, Anastasiya et al.

Ingår i ACS Pharmacology & Translational Science, s. 736-747, 2025

• DOI för Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [^99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study
• Ladda ner fulltext (pdf) av Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [^99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

The Impact of the Injected Mass of the Gastrin-Releasing Peptide Receptor Antagonist on Uptake in Breast Cancer: Lessons from a Phase I Trial of [99mTc]Tc-DB8

Bragina, Olga; Chernov, Vladimir; Larkina, Mariia; Varvashenya, Ruslan et al.

Ingår i Pharmaceutics, 2025

• DOI för The Impact of the Injected Mass of the Gastrin-Releasing Peptide Receptor Antagonist on Uptake in Breast Cancer: Lessons from a Phase I Trial of [99mTc]Tc-DB8
• Ladda ner fulltext (pdf) av The Impact of the Injected Mass of the Gastrin-Releasing Peptide Receptor Antagonist on Uptake in Breast Cancer: Lessons from a Phase I Trial of [99mTc]Tc-DB8

Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Ingår i ACS Pharmacology & Translational Science, s. 3228-3240, 2024

• DOI för Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
• Ladda ner fulltext (pdf) av Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization

Popov, Anton L.; Kolmanovich, Danil D.; Chukavin, Nikita N.; Zelepukin, Ivan V. et al.

Ingår i Molecules, 2024

• DOI för Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
• Ladda ner fulltext (pdf) av Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization

Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Larkina, Maria; Varvashenya, Ruslan; Yuldasheva, Feruza; Plotnikov, Evgenii et al.

Ingår i Molecular Pharmaceutics, s. 1919-1932, 2024

• DOI för Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Oroujeni, Maryam; Carlqvist, Matilda; Ryer, Eva; Orlova, Anna et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2024

• DOI för Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
• Ladda ner fulltext (pdf) av Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Den senaste utvecklingen av radionuklidbaserade teranostiska medel inriktad mot PSMA vid prostatacancer

Kahoori, Sahar

2024

Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile

Liu, Yongsheng; Oroujeni, Maryam; Liao, Yunqi; Vorobyeva, Anzhelika et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4038-4048, 2024

• DOI för Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
• Ladda ner fulltext (pdf) av Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile

Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

Nagy, Abel; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Landmark, Fredrika et al.

Ingår i ACS Omega, s. 36122-36133, 2024

• DOI för Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
• Ladda ner fulltext (pdf) av Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

Obeid, Karim; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Mattsson, Adam et al.

Ingår i Pharmaceutics, 2024

• DOI för GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
• Ladda ner fulltext (pdf) av GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.

Zhang, Jie; Bodenko, Vitalina; Larkina, Maria; Bezverkhniaia, Ekaterina et al.

Ingår i Journal of Controlled Release, s. 468-478, 2024

• DOI för Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
• Ladda ner fulltext (pdf) av Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.

Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Rosenström, Ulrika; Tolmachev, Vladimir et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m
• Ladda ner fulltext (pdf) av Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m

Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy

Belyaev, Iaroslav B.; Zelepukin, Ivan V.; Kotelnikova, Polina A.; Tikhonowski, Gleb V. et al.

Ingår i Advanced Science, 2024

• DOI för Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy
• Ladda ner fulltext (pdf) av Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy

Laser-synthesized plasmonic HfN-based nanoparticles as a novel multifunctional agent for photothermal therapy

Pastukhov, A. I.; Savinov, M. S.; Zelepukin, Ivan V.; Babkova, J. S. et al.

Ingår i Nanoscale, s. 17893-17907, 2024

• DOI för Laser-synthesized plasmonic HfN-based nanoparticles as a novel multifunctional agent for photothermal therapy
• Ladda ner fulltext (pdf) av Laser-synthesized plasmonic HfN-based nanoparticles as a novel multifunctional agent for photothermal therapy

Modification of contact lenses via metal-organic frameworks for glaucoma treatment

Yaremenko, Alexey V.; Melikov, Roman O.; Pechnikova, Nadezhda A.; Belyaev, Iaroslav B. et al.

Ingår i Aggregate, 2024

• DOI för Modification of contact lenses via metal-organic frameworks for glaucoma treatment
• Ladda ner fulltext (pdf) av Modification of contact lenses via metal-organic frameworks for glaucoma treatment

MPS blockade with liposomes controls pharmacokinetics of nanoparticles in a size-dependent manner

Belyaev, Iaroslav B.; Mirkasymov, Aziz B.; Rodionov, Vladislav, I; Babkova, Julia S. et al.

Ingår i Biomedical Materials, 2024

• DOI för MPS blockade with liposomes controls pharmacokinetics of nanoparticles in a size-dependent manner
• Ladda ner fulltext (pdf) av MPS blockade with liposomes controls pharmacokinetics of nanoparticles in a size-dependent manner

Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [^99mTc]Tc(CO)₃-(HE)₃-Ec1 for Visualization of EpCAM-Expressing Lung Cancer

Zelchan, Roman; Chernov, Vladimir; Medvedeva, Anna; Rybina, Anastasia et al.

Ingår i Cancers, 2024

• DOI för Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [^99mTc]Tc(CO)₃-(HE)₃-Ec1 for Visualization of EpCAM-Expressing Lung Cancer
• Ladda ner fulltext (pdf) av Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [^99mTc]Tc(CO)₃-(HE)₃-Ec1 for Visualization of EpCAM-Expressing Lung Cancer

Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion

Deyev, Sergey M.; Oroujeni, Maryam; Garousi, Javad; Graeslund, Torbjoern et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion
• Ladda ner fulltext (pdf) av Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion

Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology

Kanellopoulos, Panagiotis; Mattsson, Adam; Abouzayed, Ayman; Obeid, Karim et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2024

• DOI för Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology
• Ladda ner fulltext (pdf) av Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology

Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery

Zelepukin, Ivan V.; Shevchenko, Konstantin G.; Deyev, Sergey M.

Ingår i Perspectives, 2024

• DOI för Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery
• Ladda ner fulltext (pdf) av Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery

Shorter Peptide Nucleic Acid Probes Improve Affibody-Mediated Peptide Nucleic Acid-Based Pretargeting

Westerlund, Kristina; Oroujeni, Maryam; Gestin, Maxime; Clinton, Jacob et al.

Ingår i ACS Pharmacology & Translational Science, s. 1595-1611, 2024

• DOI för Shorter Peptide Nucleic Acid Probes Improve Affibody-Mediated Peptide Nucleic Acid-Based Pretargeting
• Ladda ner fulltext (pdf) av Shorter Peptide Nucleic Acid Probes Improve Affibody-Mediated Peptide Nucleic Acid-Based Pretargeting

Synthesis and Preclinical Evaluation of Urea-Based Prostate-Specific Membrane Antigen-Targeted Conjugates Labeled with ¹⁷⁷Lu

Machulkin, Aleksei E.; Petrov, Stanislav A.; Bodenko, Vitalina; Larkina, Mariia S. et al.

Ingår i ACS Pharmacology & Translational Science, s. 1457-1473, 2024

• DOI för Synthesis and Preclinical Evaluation of Urea-Based Prostate-Specific Membrane Antigen-Targeted Conjugates Labeled with ¹⁷⁷Lu

Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Kanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenström, Ulrika et al.

Ingår i ACS Omega, s. 18608-18616, 2024

• DOI för Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
• Ladda ner fulltext (pdf) av Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

Abouzayed, Ayman; Seitova, Kamila; Lundmark, Fanny; Bodenko, Vitalina et al.

Ingår i Frontiers in Oncology, 2023

• DOI för ¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry
• Ladda ner fulltext (pdf) av ¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry

Co-injection of anti-HER2 antibody Trastuzumab does not increase efficacy of [Lu-177]Lu-PSMA-617 therapy in an animal model of prostate cancer

Abouzayed, Ayman; Zedan, Wahed; Altai, Mohamed; Strand, Joanna et al.

Ingår i American Journal of Nuclear Medicine and Molecular Imaging, s. 107-+, 2023

Comparison of HER2-targeted affibody conjugates loaded with auristatin-and maytansine-derived drugs

Yin, Wen; Xu, Tianqi; Ding, Haozhong; Zhang, Jie et al.

Ingår i Journal of Controlled Release, s. 515-527, 2023

• DOI för Comparison of HER2-targeted affibody conjugates loaded with auristatin-and maytansine-derived drugs

Conditionally activated affibody-based prodrug targeting EGFR demonstrates improved tumour selectivity

Leitao, Charles Dahlsson; Borras, Anna Mestre; Xu, Tianqi; Oroujeni, Maryam et al.

Ingår i Journal of Controlled Release, s. 185-195, 2023

• DOI för Conditionally activated affibody-based prodrug targeting EGFR demonstrates improved tumour selectivity

Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

Haraldsson, Astrid

2023

• Ladda ner fulltext (pdf) av Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model

Xu, Tianqi; Schulga, Alexey; Konovalova, Elena; Rinne, Sara S. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model
• Ladda ner fulltext (pdf) av Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model

Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

Chernov, Vladimir; Rybina, Anastasiya; Zelchan, Roman; Medvedeva, Anna et al.

Ingår i Cancers, 2023

• DOI för Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
• Ladda ner fulltext (pdf) av Phase I Trial of [Tc-99m]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors

Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Lundmark, Fanny; Abouzayed, Ayman; Rinne, Sara S.; Timofeev, Vasiliy et al.

Ingår i Cancers, 2023

• DOI för Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation
• Ladda ner fulltext (pdf) av Preclinical Characterisation of PSMA/GRPR-Targeting Heterodimer [Ga-68]Ga-BQ7812 for PET Diagnostic Imaging of Prostate Cancer: A Step towards Clinical Translation

Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Larkina, Mariia et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)
• Ladda ner fulltext (pdf) av Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

Preclinical evaluation of novel therapeutical GRPR-targeting antagonists labeled with ¹¹¹In

Mattsson, Adam

2023

Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab

Liu, Yongsheng; Xu, Tianqi; Vorobyeva, Anzhelika; Loftenius, Annika et al.

Ingår i Cancers, 2023

• DOI för Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
• Ladda ner fulltext (pdf) av Radionuclide Therapy of HER2-Expressing Xenografts Using [Lu-177]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab

Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures

Hasnowo, Lutfi A.; Larkina, Maria S.; Plotnikov, Evgenii; Bodenko, Vitalina et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
• Ladda ner fulltext (pdf) av Synthesis, I-123-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures

The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity

Abouzayed, Ayman; Borin, Jesper; Lundmark, Fanny; Rybina, Anastasiya et al.

Ingår i Diagnostics, 2023

• DOI för The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity
• Ladda ner fulltext (pdf) av The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity

Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125

Tolmachev, Vladimir; Bodenko, Vitalina; Orlova, Anna; Schulga, Alexey et al.

Ingår i Oncology Letters, 2023

• DOI för Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125
• Ladda ner fulltext (pdf) av Visualization of epithelial cell adhesion molecule-expressing renal cell carcinoma xenografts using designed ankyrin repeat protein Ec1 labelled with Tc-99m and I-125

Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis

Liu, Yongsheng; Gueler, Rezan; Liao, Yunqi; Vorobyeva, Anzhelika et al.

Ingår i Pharmaceutics, 2022

• DOI för Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis
• Ladda ner fulltext (pdf) av Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis

Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Lundmark, Fanny; Olanders, Gustav; Rinne, Sara Sophie; Abouzayed, Ayman et al.

Ingår i Pharmaceutics, 2022

• DOI för Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
• Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands