GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

Obeid, Karim; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Mattsson, Adam et al.

Ingår i Pharmaceutics, 2024

• DOI för GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
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Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.

Zhang, Jie; Bodenko, Vitalina; Larkina, Maria; Bezverkhniaia, Ekaterina et al.

Ingår i Journal of Controlled Release, s. 468-478, 2024

• DOI för Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
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Introduction of a fatty acid chain modification to prolong circulatory half-life of a radioligand towards glucose-dependent insulinotropic polypeptide receptor

Khalil, Amina; Hakhverdyan, Sona; Cheung, Pierre; Bossart, Martin et al.

Ingår i Nuclear Medicine and Biology, 2024

• DOI för Introduction of a fatty acid chain modification to prolong circulatory half-life of a radioligand towards glucose-dependent insulinotropic polypeptide receptor
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Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes

Vyakaranam, Achyut Ram; Mahamed, Maryama M.; Hellman, Per; Eriksson, Olof et al.

Ingår i Diabetologia, s. 199-208, 2024

• DOI för Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
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Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule

Wegrzyniak, Olivia; Lechi, Francesco; Mitran, Bogdan; Cheung, Pierre et al.

Ingår i iScience, 2024

• DOI för Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study

Liggieri, Francesco; Chiodaroli, Elena; Pellegrini, Mariangela; Puuvuori, Emmi et al.

Ingår i Intensive Care Medicine Experimental, 2024

• DOI för Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study
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Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

Kanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenström, Ulrika et al.

Ingår i ACS Omega, s. 18608-18616, 2024

• DOI för Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
• Ladda ner fulltext (pdf) av Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Ingår i Pharmaceutics, 2023

• DOI för [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44
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Bone formation beyond the skeletal envelope using calcium phosphate granules packed into a collagen pouch-a pilot study

Guillet, Claire; Birgersson, Ulrik; Engstrand, Thomas; Åberg, Jonas et al.

Ingår i Biomedical Materials, 2023

• DOI för Bone formation beyond the skeletal envelope using calcium phosphate granules packed into a collagen pouch-a pilot study
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Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels

Echeverri Correa, Estefania; Skjöldebrand, Charlotte; O'Callaghan, Paul; Palmquist, Anders et al.

Ingår i Biomaterials Science, s. 3144-3158, 2023

• DOI för Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels
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Human Epidermal Growth Factor Receptor 2-Targeting [⁶⁸Ga]Ga-ABY-025 PET/CT Predicts Early Metabolic Response in Metastatic Breast Cancer.

Alhuseinalkhudhur, Ali; Lindman, Henrik; Liss, Per; Sundin, Tora et al.

Ingår i Journal of Nuclear Medicine, s. 1364-1370, 2023

• DOI för Human Epidermal Growth Factor Receptor 2-Targeting [⁶⁸Ga]Ga-ABY-025 PET/CT Predicts Early Metabolic Response in Metastatic Breast Cancer.
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Human Whole Blood Interactions with Craniomaxillofacial Reconstruction Materials: Exploring In Vitro the Role of Blood Cascades and Leukocytes in Early Healing Events

Lopes, Viviana; Birgersson, Ulrik; Manivel, Vivek Anand; Hulsart Billström, Gry et al.

Ingår i Journal of Functional Biomaterials, 2023

• DOI för Human Whole Blood Interactions with Craniomaxillofacial Reconstruction Materials: Exploring In Vitro the Role of Blood Cascades and Leukocytes in Early Healing Events
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Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

Velikyan, Irina; Bossart, Martin; Haack, Torsten; Laitinen, Iina et al.

Ingår i Pharmaceuticals, 2023

• DOI för Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences
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In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES

Antoni, Gunnar; Lubberink, Mark; Sörensen, Jens; Lindström, Elin et al.

Ingår i Journal of Nuclear Medicine, s. 145-148, 2023

• DOI för In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES
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Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity

Geissel, Felix J.; Platania, Varvara; De Berardinis, Niccoló; Skjöldebrand, Charlotte et al.

Ingår i Advanced Materials Interfaces, 2023

• DOI för Nanostructured Ag-Bioglass Implant Coatings with Antibacterial and Osteogenic Activity
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PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Ingår i Journal of Nuclear Medicine, s. 423-429, 2023

• DOI för PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Ingår i EJNMMI Research, s. 107, 2023

• DOI för Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.
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Radiotracers for Imaging of Fibrosis: Advances during the Last Two Decades and Future Directions

Eriksson, Olof; Velikyan, Irina

Ingår i Pharmaceuticals, 2023

• DOI för Radiotracers for Imaging of Fibrosis: Advances during the Last Two Decades and Future Directions
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Reducing the dissolution rate of silicon nitride coatings for spinal implants using Fe and C as alloying elements

Echeverri Correa, Estefania; Skjöldebrand, Charlotte; Palmquist, Anders; Hulsart Billström, Gry et al.

2023

Translational PET imaging of inflammation

Puuvuori, Emmi

2023

• Ladda ner fulltext (pdf) av Translational PET imaging of inflammation

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Bossart, Martin; Wagner, Michael; Elvert, Ralf; Evers, Andreas et al.

Ingår i Cell Metabolism, s. 59-+, 2022

• DOI för Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Ingår i Journal of Nuclear Medicine, s. 794-800, 2022

• DOI för Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes

Guiding bone formation using semi‐onlay calcium phosphate implants in an ovine calvarial model

Hulsart-Billstrom, Gry; Lopes, Viviana; Illies, Christopher; Gallinetti, Sara et al.

Ingår i Journal of Tissue Engineering and Regenerative Medicine, s. 435-447, 2022

• DOI för Guiding bone formation using semi‐onlay calcium phosphate implants in an ovine calvarial model
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PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

Puuvuori, Emmi; Liggieri, Francesco; Velikyan, Irina; Chiodaroli, Elena et al.

Ingår i EJNMMI Research, 2022

• DOI för PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
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Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobium

Skjöldebrand, Charlotte; Echeverri Correa, Estefania; Hulsart Billström, Gry; Persson, Cecilia

Ingår i Biomaterials Science, s. 3757-3769, 2022

• DOI för Tailoring the dissolution rate and in vitro cell response of silicon nitride coatings through combinatorial sputtering with chromium and niobium
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Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Ingår i Scientific Reports, 2021

• DOI för Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
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Dissolution and biocompatibility of combinatorially sputtered SiCrNbN coatings

Echeverri Correa, Estefania; Skjöldebrand, Charlotte; Hulsart Billström, Gry; Persson, Cecilia

2021

Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Ingår i Diabetes, s. 842-853, 2021

• DOI för Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography

Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

Manell, Elin; Puuvuori, Emmi; Svensson, Anna; Velikyan, Irina et al.

Ingår i BMJ Open Diabetes Research & Care, 2021

• DOI för Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography
• Ladda ner fulltext (pdf) av Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Velikyan, Irina; Rosenström, Ulrika; Rosestedt, Maria; Eriksson, Olof et al.

Ingår i Pharmaceuticals, 2021

• DOI för Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis
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Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Ingår i Diabetes, s. 966-975, 2021

• DOI för Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

News ways of understanding the complex biology of diabetes using PET

Eriksson, Olof; Långström, Bengt; Antoni, Gunnar

Ingår i Nuclear Medicine and Biology, s. 65-71, 2021

• DOI för News ways of understanding the complex biology of diabetes using PET

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Ingår i Biomedicines, 2021

• DOI för PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs
• Ladda ner fulltext (pdf) av PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans

Puuvuori, Emmi; Rokka, Johanna; Carlsson, Per-Ola; Li, Zhanchun et al.

Ingår i Scientific Reports, 2021

• DOI för Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans
• Ladda ner fulltext (pdf) av Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Ingår i Nuclear Medicine and Biology, s. 54-62, 2021

• DOI för Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1
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Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease

Wegrzyniak, Olivia; Rosestedt, Maria; Eriksson, Olof

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease
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Targeted ToF-SIMS Analysis of Macrophage Content from a Human Cranial Triphasic Calcium Phosphate Implant

Malmberg, Per; Lopes, Viviana; Hulsart Billström, Gry; Gallinetti, Sara et al.

Ingår i ACS Applied Bio Materials, s. 6791-6798, 2021

• DOI för Targeted ToF-SIMS Analysis of Macrophage Content from a Human Cranial Triphasic Calcium Phosphate Implant
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The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies

Cheung, Pierre; Eriksson, Olof

Ingår i Biomedicines, 2021

• DOI för The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies
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Theranostic Approach in Breast Cancer A Treasured Tailor for Future Oncology

Jokar, Narges; Velikyan, Irina; Ahmadzadehfar, Hojjat; Rekabpour, Seyed Javad et al.

Ingår i Clinical Nuclear Medicine, 2021

• DOI för Theranostic Approach in Breast Cancer A Treasured Tailor for Future Oncology

[¹¹C]5-Hydroxy-tryptophan model for quantitative assessment of in vivo serotonin biosynthesis, retention and degradation in the endocrine pancreas

Lubberink, Mark; Eriksson, Olof

Ingår i American Journal of Nuclear Medicine and Molecular Imaging, s. 226-234, 2020

Automated GMP-Compliant Production of [Ga-68]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans

Wagner, Michael; Doverfjord, Johan G.; Tillner, Joachim; Antoni, Gunnar et al.

Ingår i Pharmaceuticals, 2020

• DOI för Automated GMP-Compliant Production of [Ga-68]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans
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(Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer

Velikyan, Irina

Ingår i Pharmaceuticals, 2020

• DOI för (Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer
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Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes

Eriksson, Olof; Haack, Torsten; Hijazi, Youssef; Teichert, Lenore et al.

Ingår i Scientific Reports, 2020

• DOI för Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes
• Ladda ner fulltext (pdf) av Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes

Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

Ingår i Cancers, 2019

• DOI för Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer
• Ladda ner fulltext (pdf) av Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Impact of particles derived from spinal implant materials on glial survival and activation

Echeverri Correa, Estefania; O'Callaghan, Paul; Ferraz, Natalia; Hulsart Billström, Gry et al.

Lead compound identification from first-in-class high affinity Affibody molecules binders towards DGCR2

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Khalil, Amina et al.

Osteogenic potential of a calcium phosphate-PLLA composite structure

Echeverri Correa, Estefanía; Grzeszczak, Ana; Shtender, Vitalii; Åberg, Jonas et al.

Positron Emission Tomography imaging of CD69 in a murine model of rheumatoid arthritis

Puuvuori, Emmi; Shen, Yunbing; Hulsart Billström, Gry; Mitran, Bogdan et al.

Preclinical evaluation of Affibody molecule ¹⁸F-TZ-Z_AM106 for PET imaging of DGCR2

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Synthesis and Preclinical Evaluation of GRPR Antagonist [¹⁸F]-MeTz-PEG₂-RM26 for Position Emission Tomography

Lundmark, Fanny; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir et al.