EMBLA
Forskargruppen EMBLA leds av Prof. Maria Tenje och utvecklar nya mikrofluidala forskningsverktyg för livsvetenskaperna
The EMBLA group - Enabling Microtechnologies for Biomedical and Life science Applications - is led by Prof. Maria Tenje and comprises researchers with backgrounds in material science, nanotechnology, chemistry and biology. The research activities of EMBLA are focused on droplet based microfluidics and organs-on-chip.
We have an interdisciplinary character of our projects and we use microfabrication techniques combined with microfluidics to develop new platforms for visualisation and characterisation of cells to learn more about the human biology. We address both fundamental research questions and develop microsystems that in the near future could find clinical and industrial applications.
Vi är mycket tacksamma för anslag från våra bidragsgivare
Forskningsintressen
Organs-on-Chip
Classical and exotic microfabrication techniques are used to modify the mechanical and chemical properties of biologically derived hydrogels for controlled cell adhesion and proliferation.
Acoustofluidics
Acoustic forces are used to manipulate cells and bioparticles in microfluidic systems. We specialise in acoustic trapping and free-flow acoustophoresis in two-phase systems.
Droplet Microfluidics
We research droplet microfluidic systems using both aqeuous and hydrogel-based droplets and use these for rapid biological assays, specifically focused on studying cell growth.
Integrated electronic sensors
Microstructured metal electrodes are integrated in several of the microfluidic systems we fabricate. The electrodes can be used to stimulate cells, analyse in situ temperature and measure the tightness of cell junctions in real time.
Biomaterials-on-Chip
To assess the potential of biomaterials under more relevant physiological conditions, we integrate biomaterials into microfluidic systems for studies of their biological properties.
Microfabrication
We fabricate microfluidic systems for several different life science applications in Si, glass and different polymers on the length scale from sub-µm to mm. The pilot facility Customized Microfluidics work with external parties.
Gruppmedlemmar
Publikationer
3D Acoustic Mixing via Two-photon-printed Microstructures
2025
A Microfluidic Platform for In Situ Studies of Bacteria Electroporation
Ingår i Advanced Materials Technologies, 2025
- DOI för A Microfluidic Platform for In Situ Studies of Bacteria Electroporation
- Ladda ner fulltext (pdf) av A Microfluidic Platform for In Situ Studies of Bacteria Electroporation
Ingår i Journal of the Royal Society Interface, 2025
- DOI för Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures
- Ladda ner fulltext (pdf) av Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures
Dynamics of non-Newtonian agarose gel droplet formation in two-phase microfluidic systems
Ingår i Physics of fluids, 2025
- DOI för Dynamics of non-Newtonian agarose gel droplet formation in two-phase microfluidic systems
- Ladda ner fulltext (pdf) av Dynamics of non-Newtonian agarose gel droplet formation in two-phase microfluidic systems
Ingår i Journal of the Acoustical Society of America, s. 4262-4272, 2025
- DOI för Effects of the choice of the continuous phase in droplet microfluidics on internal particle manipulation with acoustophoresis
- Ladda ner fulltext (pdf) av Effects of the choice of the continuous phase in droplet microfluidics on internal particle manipulation with acoustophoresis
2024
Ingår i Advanced Materials Technologies, 2024
- DOI för A perfusable multi-hydrogel vasculature on-chip engineered by 2-photon 3D printing and scaffold molding to improve microfabrication fidelity in hydrogels
- Ladda ner fulltext (pdf) av A perfusable multi-hydrogel vasculature on-chip engineered by 2-photon 3D printing and scaffold molding to improve microfabrication fidelity in hydrogels
Acoustic fluid manipulation via two-photon-printed resonant microstructures
2024
Design optimization of acoustic cavity traps for effective microparticle trapping
Ingår i Acoustofluidics 2024, 2024
Exploring the dependence of hydrogel sample thickness on resulting apparent Young's modulus
2024
- Fler publikationer
Alumni
- Yuan Cui, PhD 2024
- Anna Fornell, Researcher 2023-2024
- Samah Abousharieha, Researcher 2020-2024
- Laurent Barbe, Researcher 2017-2024
- Susan Peacock, Project Coordinator 2017-2024
- Rebecka Norman, MSc 2024
- Praneeth Karempudi, PhD 2023
- Kristel Parv, Project Coordinator 2023
- Federico Cantoni, PhD 2023
- Lulu Wu, PhD 2023
- Nuzhet Inci Kilic, PhD student 2022-2023
- Femke Tolboom, MSc 2023
- Lilli Ahopelto, MSc 2023
- Abdul Raouf Atif, PhD 2023
- Isabel Burdallo, Project Coordinator 2022-2023
- Sarah-Sophia Carter, PhD 2022
- Ana Maria Porras Hernandez, PhD 2022
- Zhenhua Liu, PhD 2022
- Susanna Wärmegård, MSc 2022
- Atena Khaji, Postdoc 2017-2022
- Hannah Pohlit, Postdoc 2018-2022
- Linnéa Soto Carlsson, BSc 2022
- Albin Jonasson, BSc 2022
- Samuel Lindner, MSc 2022
- Ramon Katoele, Intern 2022
- Maja Grape, MSc 2022
- Gemma Mestres, Senior Lecturer 2015-2021
- Anna Kim, Researcher 2021
- Maryam Shojaee, Guest PhD Student 2021
- Alina Beer, MSc 2021
- Tinde Höjer, MSc 2021
- Hanlu Deng, MSc 2021
- Björn Stenestam, MSc 2020
- Daniel Feldt, Intern 2020
- Qian Shi, MSc 2020
- Anna Fornell, Postdoc 2018-2020
- Martin Andersson, Senior Research Engineer 2020
- Mara Lucchetti, Visiting PhD student 2020
- Milena De Albuquerque Moreira, Senior Research Engineer 2018-2019
- Sean Searle, Visiting PhD student 2017-2019
- Björn Stenestam, Intern 2019
- Gianluca Bortolini, Intern 2019
- Per Söderbäck, MSc 2019
- Julia Levy, Intern 2019
- Fredrik Lindeberg, MSc 2019
- Jingyi Sun, MSc 2019
- Gabriel Werr, Intern 2019
- Anna Blasi, MSc 2019
- Lars Erdmann, MSc 2019
- Anna Fornell, PhD 2018
- Noelia D’Elía, Visiting postdoc, 2018
- Ramón Rial Silva, Visiting PhD student, 2018
- Fredrik Lindeberg, Intern 2018
- Gabriel Werr, MSc 2018
- Klara Björnander Rahimi, MSc 2018
- Abdul Raouf Atif, MSc 2018
- Anette Wolff, Licentiate 2019
- Rebecka Sörensen, MSc 2018
- Sajal Tiwari, MSc 2018
- Axel Happstadius, MSc 2017
- Frida Sjögren, Licentiate 2017
- Krishna Narayan, MSc 2017
- Simonne Jocic, MSc 2016
- Anabel Villanueav, BSc 2016
- Nicki Nordh, MSc 2015
- Arun Thumula, MSc 2016
- Ana María Porras, MSc 2016
- Karolina Svensson, MSc 2017
- Emma Thomée, MSc 2017
- Mathias Ohlin, Postdoc 2015-2017