Introduction to NMR spectroscopy, 4 credits
Introduktion till NMR spektroskopi
Course information
Language of instruction: English
Course period: Spring 2025
Course structure: Campus
Recommended prerequisites
B.Sc/M.Sc in Chemsitry, Biology, Physics, Material science or Pharmacy, e.g. Civilingenjörsprogrammet i molekylär bioteknik Biomedicinareprogrammet
Learning outcomes
On completion of the course, the student should be able to:
- account for the theoretical foundation of the most commonly used NMR experiments
- relate NMR parameters such as chemical shift, scalar coupling constants, and relaxation time constants to molecular structure
- gain insight into practical applications of NMR, the role it plays in chemistry, biology and pharmacy, and how it pertains to their own research
- prepare samples for NMR measurement, choose and perform the right NMR experiments for their own research, and interpret and document their result
Learning outcomes for doctoral degree
The goal of this course is to enable students to add another tool to their scientific toolbox. It will allow them to gain deep familiarity with an important research method and to understand how it can be implemented in their own research. It will provide them with the insight to be able to critically assess the quality of work in the field. It will give them the skill set to design and implement experiments using the method, and to aptly trouble shoot when issues arise. It will also enable them to spread their knowledge to others and effectively advice and train other users in their respective research groups. The course supports learning outcomes A2 and B1 from PhD students individual study Plans.
Course contents
The basics of NMR spectroscopy, including vector model and its relation to pulse sequences. Function of pulse sequences. Parameter calibration and optimization. Polarization transfer and its application. Solvents suppression. Selective experiments. Diffusion measurements and DOSY.
Instruction
Lectures; Labs; computer labs; student-led seminars; Project where students can apply NMR to their own research (arrangements will be made for students who do not have any research to work on).
Assessment
Assessment is based on attendance (20%), written report (30%) and a final project (50%). The final project will be presented orally in a seminar.
Course examiner
Ruisheng Xiong, ruisheng.xiong@kemi.uu.se
Department with main responsibility
Department of Chemistry - BMC
Contact person/s
Ruisheng Xiong, ruisheng.xiong@kemi.uu.se
Application
Submit the application for admission to: ruisheng.xiong@kemi.uu.se
Submit the application not later than: 2025-01-15