Olle Korsgren – Diabetesforskning

DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Ingår i Scientific Reports, 2025

• DOI för DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue

Yngve, Erik; Ingvast, Sofie; Korsgren, Olle; Yu, Di

Ingår i Upsala Journal of Medical Sciences, 2025

• DOI för Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue
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Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data

Teixeira, Pedro F.; Battelino, Tadej; Carlsson, Anneli; Gudbjornsdottir, Soffia et al.

Ingår i Diabetologia, s. 985-994, 2024

• DOI för Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data
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Illuminating the complete ߟ-cell mass of the human pancreas: signifying a new view on the islets of Langerhans

Lehrstrand, Joakim; Davies, Wayne I. L.; Hahn, Max; Korsgren, Olle et al.

Ingår i Nature Communications, 2024

• DOI för Illuminating the complete ߟ-cell mass of the human pancreas: signifying a new view on the islets of Langerhans
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Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Puuvuori, Emmi; Shen, Yunbing; Hulsart-Billström, Gry; Mitran, Bogdan et al.

Ingår i Journal of Nuclear Medicine, s. 294-299, 2024

• DOI för Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule

Wegrzyniak, Olivia; Lechi, Francesco; Mitran, Bogdan; Cheung, Pierre et al.

Ingår i iScience, 2024

• DOI för Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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Outcome after total pancreatectomy with islet autotransplantation: A European single-center study

Froberg, Klara; Halimi, Asif; Vujasinovic, Miroslav; Caballero-Corbalán, José et al.

Ingår i Scandinavian Journal of Surgery, s. 80-87, 2024

• DOI för Outcome after total pancreatectomy with islet autotransplantation: A European single-center study
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Reduced expression of central innate defense molecules in pancreatic biopsies from subjects with Type 1 diabetes

Tegehall, Angie; Ingvast, Sofie; Krogvold, Lars; Dahl-Jørgensen, Knut et al.

Ingår i Acta Diabetologica, 2024

• DOI för Reduced expression of central innate defense molecules in pancreatic biopsies from subjects with Type 1 diabetes
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[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Ingår i Pharmaceutics, 2023

• DOI för [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44
• Ladda ner fulltext (pdf) av [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Wegrzyniak, Olivia; Zhang, Bo; Rokka, Johanna; Rosestedt, Maria et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2023

• DOI för Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β
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PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Ingår i Journal of Nuclear Medicine, s. 423-429, 2023

• DOI för PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Ingår i EJNMMI Research, s. 107, 2023

• DOI för Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.
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A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angie; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Ingår i Acta Diabetologica, s. 1011-1018, 2022

• DOI för A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats
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Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Granlund, Louise; Hedin, Anders; Korsgren, Olle; Skog, Oskar et al.

Ingår i PLOS ONE, 2022

• DOI för Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Golec, Ewelina; Ekstrom, Alexander; Noga, Maciej; Omar-Hmeadi, Muhmmad et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI för Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
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Islet Gene View-a tool to facilitate islet research

Asplund, Olof; Storm, Petter; Chandra, Vikash; Hatem, Gad et al.

Ingår i Life Science Alliance, 2022

• DOI för Islet Gene View-a tool to facilitate islet research
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Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Ingår i Cell Reports Medicine, 2022

• DOI för Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
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PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

Puuvuori, Emmi; Liggieri, Francesco; Velikyan, Irina; Chiodaroli, Elena et al.

Ingår i EJNMMI Research, 2022

• DOI för PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
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3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas

Hahn, Max; Nord, Christoffer; Eriksson, Maria; Morini, Federico et al.

Ingår i Communications Biology, 2021

• DOI för 3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas
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Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up

Saellstrom, Sara; Sadeghi, Arian; Eriksson, Emma; Segall, Thomas et al.

Ingår i Frontiers in Veterinary Science, 2021

• DOI för Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up
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Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation

Bergström, Marcus; Yao, Ming; Müller, Malin; Korsgren, Olle et al.

Ingår i Transplant International, s. 2816-2823, 2021

• DOI för Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation
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Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Ingår i Diabetologia, s. 2491-2501, 2021

• DOI för Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
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Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Ingår i Scientific Reports, 2021

• DOI för Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
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Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Ingår i BMJ Open Diabetes Research & Care, 2021

• DOI för Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes
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Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Ingår i Diabetes, s. 966-975, 2021

• DOI för Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Ingår i Circulation Research, s. 1694-1707, 2021

• DOI för Perivascular macrophages regulate blood flow following tissue damage

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Ingår i Biomedicines, 2021

• DOI för PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs
• Ladda ner fulltext (pdf) av PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes

Markmann, James F.; Rickels, Michael R.; Eggerman, Thomas L.; Bridges, Nancy D. et al.

Ingår i American Journal of Transplantation, s. 1477-1492, 2021

• DOI för Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Ingår i Nuclear Medicine and Biology, s. 54-62, 2021

• DOI för Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1
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Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Per-Anton; Hedin, Anders; Granlund, Louise et al.

Ingår i PLOS ONE, 2021

• DOI för Transcriptional analysis of islets of Langerhans from organ donors of different ages

US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

Piemonti, Lorenzo; Andres, Axel; Casey, John; de Koning, Eelco et al.

Ingår i Transplant International, s. 1182-1186, 2021

• DOI för US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study

Nano, Rita; Kerr-Conte, Julie A.; Scholz, Hanne; Engelse, Marten et al.

Ingår i Transplantation, s. 190-196, 2020

• DOI för Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study

Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function

Abadpour, Shadab; Tyrberg, Bjorn; Schive, Simen W.; Huldt, Charlotte Wennberg et al.

Ingår i Diabetologia, s. 1355-1367, 2020

• DOI för Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function
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Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence

Hahn, Max; Nord, Christoffer; Franklin, Oskar; Alanentalo, Tomas et al.

Ingår i Scientific Reports, 2020

• DOI för Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence
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Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

Neiman, Daniel; Gillis, David; Piyanzin, Sheina; Cohen, Daniel et al.

Ingår i JCI Insight, 2020

• DOI för Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Skog, Oskar; Korsgren, Olle

Ingår i Acta Diabetologica, s. 503-511, 2020

• DOI för On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes
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Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes

Maffi, Paola; Lundgren, Torbjorn; Tufveson, Gunnar; Rafael, Ehab et al.

Ingår i Diabetes Care, s. 710-718, 2020

• DOI för Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes

The role of vitamin D in the aetiology of type 1 diabetes

Korsgren, Olle

Ingår i Diabetologia, s. 1279-1280, 2020

• DOI för The role of vitamin D in the aetiology of type 1 diabetes

Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

Jonsson, Alexander; Hedin, Anders; Müller, Malin; Skog, Oskar et al.

Ingår i Scientific Reports, 2020

• DOI för Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism
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A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Helker, Christian S M; Mullapudi, Sri-Teja; Mueller, Laura M; Preussner, Jens et al.

Ingår i Development, 2019

• DOI för A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Seiron, Peter; Wiberg, Anna; Kuric, Enida; Krogvold, Lars et al.

Ingår i The journal of pathology. Clinical research, s. 248-255, 2019

• DOI för Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
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Characterization of host defense molecules in the human pancreas

Stenwall, Anton; Ingvast, Sofie; Skog, Oskar; Korsgren, Olle

Ingår i Islets, s. 89-101, 2019

• DOI för Characterization of host defense molecules in the human pancreas
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Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells

Bergström, Marcus; Müller, Malin; Karlsson, Marie; Scholz, Hanne et al.

Ingår i Cell Transplantation, s. 1603-1613, 2019

• DOI för Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells
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Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation

Brandhorst, Heide; Johnson, Paul R.; Moench, Johanna; Kurfuerst, Manfred et al.

Ingår i Cell Transplantation, s. 176-184, 2019

• DOI för Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation
• Ladda ner fulltext (pdf) av Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, Olle; Skyler, Jay S; Skog, Oskar; Sundberg, Frida et al.

Ingår i Nature Reviews Endocrinology, s. 623-624, 2019

• DOI för Imagining a better future for all people with type 1 diabetes mellitus

Islets for Research: Nothing Is Perfect, but We Can Do Better

Nano, Rita; Kerr-Conte, Julie A.; Bosco, Domenico; Karlsson, Marie et al.

Ingår i Diabetes, s. 1541-1543, 2019

• DOI för Islets for Research: Nothing Is Perfect, but We Can Do Better

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Skog, Oskar; Klingel, Karin; Roivainen, Merja; Korsgren, Olle

Ingår i Diabetologia, s. 1097-1099, 2019

• DOI för Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

von Zur-Mühlen, Bengt; Lundgren, Torbjorn; Bayman, Levent; Berne, Christian et al.

Ingår i Transplantation, s. 630-637, 2019

• DOI för Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation
• Ladda ner fulltext (pdf) av Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Jonsson, Alexander; Yngve, Erik; Karlsson, Marie; Ingvast, Sofie et al.

Ingår i Journal of Histochemistry and Cytochemistry, s. 99-105, 2019

• DOI för Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Proton MR spectroscopy of human pancreas allografts

Weis, Jan; Ahlström, Håkan; Korsgren, Olle

Ingår i Magnetic Resonance Materials in Physics, Biology and Medicine, s. 511-517, 2019

• DOI för Proton MR spectroscopy of human pancreas allografts
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Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Nuclear Medicine and Biology, s. 1-10, 2019

• DOI för Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Teplizumab in Relatives at Risk for Type 1 Diabetes

Korsgren, Olle; Skog, Oskar; Ludvigsson, Johnny

Ingår i New England Journal of Medicine, s. 1879-1880, 2019

• DOI för Teplizumab in Relatives at Risk for Type 1 Diabetes

Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Skog, Oskar; Korsgren, Olle

Ingår i Diabetes, obesity and metabolism, s. 775-785, 2018

• DOI för Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas

Eich, Torsten; Ståhle, Magnus U.; Gustafsson, Bengt; Horneland, Rune et al.

Ingår i Cell Transplantation, s. 1031-1038, 2018

• DOI för Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas
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Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Gotthardt, Martin; Eizirik, Decio L.; Aanstoot, Henk-Jan; Korsgren, Olle et al.

Ingår i Diabetologia, s. 2516-2519, 2018

• DOI för Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

Lundberg, Marcus; Stenwall, Per-Anton; Tegehall, Angie; Korsgren, Olle et al.

Ingår i Islets, s. 69-79, 2018

• DOI för Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

In Vivo Visualization of beta-Cells by Targeting of GPR44

Eriksson, Olof; Johnström, Peter; Cselenyi, Zsolt; Jahan, Mahabuba et al.

Ingår i Diabetes, s. 182-192, 2018

• DOI för In Vivo Visualization of beta-Cells by Targeting of GPR44

Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT

Abadpour, Shadab; Halvorsen, Bente; Sahraoui, Afaf; Korsgren, Olle et al.

Ingår i Journal of Molecular Endocrinology, s. 171-183, 2018

• DOI för Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs, Anke; Gliwiński, Mateusz; Grageda, Nathali; Spiering, Rachel et al.

Ingår i Frontiers in Immunology, 2018

• DOI för Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.
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No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Kuric, Enida; Krogvold, Lars; Hanssen, Kristian F.; Dahl-Jorgensen, Knut et al.

Ingår i American Journal of Pathology, s. 1744-1748, 2018

• DOI för No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Eriksson, Olof; Korsgren, Olle; Selvaraju, Ram Kumar; Mollaret, Marjorie et al.

Ingår i Acta Diabetologica, s. 49-57, 2018

• DOI för Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4
• Ladda ner fulltext (pdf) av Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Ingår i European Journal of Clinical Investigation, s. 44-45, 2018

• DOI för Perivascular macrophages regulate blood flow following tissue damage

The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan, Mahabuba; Johnström, Peter; Selvaraju, Ramkumar; Svedberg, Marie et al.

Ingår i EJNMMI Research, 2018

• DOI för The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.
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Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

Carlsson, Per-Ola; Espes, Daniel; Sedigh, Amir; Rotem, Avi et al.

Ingår i American Journal of Transplantation, s. 1735-1744, 2018

• DOI för Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
• Ladda ner fulltext (pdf) av Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

[(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Martinell, Mats et al.

Ingår i Diabetes, s. 1286-1292, 2017

• DOI för [(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Characterization of resident lymphocytes in human pancreatic islets

Radenkovic, M; Uvebrant, K; Skog, Oskar; Sarmiento, L et al.

Ingår i Clinical and Experimental Immunology, s. 418-427, 2017

• DOI för Characterization of resident lymphocytes in human pancreatic islets

Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Skog, Oskar; Korsgren, Olle

Ingår i Diabetes, 2017

• DOI för Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Cost and clinical outcome of islet transplantation in Norway 2010-2015

Schive, Simen W.; Foss, Aksel; Sahraoui, Afaf; Kloster-Jensen, Kristine et al.

Ingår i Clinical Transplantation, 2017

• DOI för Cost and clinical outcome of islet transplantation in Norway 2010-2015

Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Kuric, Enida; Seiron, Peter; Krogvold, Lars; Edwin, Bjørn et al.

Ingår i American Journal of Pathology, s. 581-588, 2017

• DOI för Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Direct Substrate Delivery into Mitochondrial-Fission Deficient Pancreatic Islets Rescues Insulin Secretion

Kabra, Uma D; Pfuhlmann, Katrin; Migliorini, Adriana; Keipert, Susanne et al.

Ingår i Diabetes, s. 1247-1257, 2017

• DOI för Direct Substrate Delivery into Mitochondrial-Fission Deficient Pancreatic Islets Rescues Insulin Secretion

Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

Abadpour, Shadab; Göpel, Sven O.; Schive, Simen W.; Korsgren, Olle et al.

Ingår i Scientific Reports, 2017

• DOI för Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis
• Ladda ner fulltext (pdf) av Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

Schive, Simen W.; Mirlashari, Mohammad Reza; Hasvold, Grete; Wang, Mengyu et al.

Ingår i Cell Medicine, s. 103-116, 2017

• DOI för Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

Insulitis in human diabetes: a histological evaluation of donor pancreases

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Ingår i Diabetologia, s. 346-353, 2017

• DOI för Insulitis in human diabetes: a histological evaluation of donor pancreases
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Islet Encapsulation: Physiological Possibilities and Limitations

Korsgren, Olle

Ingår i Diabetes, s. 1748-1754, 2017

• DOI för Islet Encapsulation: Physiological Possibilities and Limitations

Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation

Brandhorst, Daniel; Parnaud, Geraldine; Friberg, Andrew; Lavallard, Vanessa et al.

Ingår i Cell Transplantation, s. 1688-1693, 2017

• DOI för Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation
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Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report

Horneland, R.; Guvag, S.; Korsgren, Olle; Aandahl, E.

Ingår i American Journal of Transplantation, s. 693-694, 2017

• DOI för Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report

Pre-transplantation ³¹P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts: A feasibility study

Carlbom, Lina; Weis, Jan; Johansson, Lars; Korsgren, Olle et al.

Ingår i Magnetic Resonance Imaging, s. 98-102, 2017

• DOI för Pre-transplantation ³¹P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts: A feasibility study

Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity

Brandhorst, Heide; Johnson, Paul R. V.; Korsgren, Olle; Brandhorst, Daniel

Ingår i Cell Transplantation, s. 1733-1741, 2017

• DOI för Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity
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Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Ingår i Diabetologia, s. 756-757, 2017

• DOI för Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas

Korsgren, Erik; Korsgren, Olle

Ingår i Diabetes, s. 1004-1008, 2016

• DOI för An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

Domsgen, Erna; Lind, Katharina; Kong, Lingjia; Huhn, Michael H. et al.

Ingår i Scientific Reports, 2016

• DOI för An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets
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Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

Rydén, Anneli; Nyman, Gorel; Nalin, Lovisa; Andreasson, Susanne et al.

Ingår i Nuclear Medicine and Biology, s. 397-402, 2016

• DOI för Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Hårdstedt, Maria; Lindblom, Susanne; Karlsson-Para, Alex; Nilsson, Bo et al.

Ingår i Cell Transplantation, s. 503-515, 2016

• DOI för Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation

Brandhorst, Heide; Kurfuerst, Manfred; Johnson, Paul R.; Korsgren, Olle et al.

Ingår i TRANSPLANTATION DIRECT, 2016

• DOI för Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation
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Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation

Ståhle, Magnus; Foss, Aksel; Gustafsson, Bengt; Lempinen, Marko et al.

Ingår i Cell Transplantation, s. 2269-2276, 2016

• DOI för Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation
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Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

Markmann, James F.; Bartlett, Stephen T.; Johnson, Paul; Korsgren, Olle et al.

Ingår i Transplantation, 2016

• DOI för Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

von Herrath, M. G.; Korsgren, Olle; Atkinson, M. A.

Ingår i Clinical and Experimental Immunology, s. 1-7, 2016

• DOI för Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial

Cooper, David K. C.; Bottino, Rita; Gianello, Pierre; Graham, Melanie et al.

Ingår i Xenotransplantation, s. 46-52, 2016

• DOI för First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial

Glucose Effectiveness: The Mouse Trap in the Development of Novel beta-Cell Replacement Therapies

Korsgren, Erik; Korsgren, Olle

Ingår i Transplantation, s. 111-115, 2016

• DOI för Glucose Effectiveness: The Mouse Trap in the Development of Novel beta-Cell Replacement Therapies

GPR44 is a pancreatic protein restricted to the human beta cell

Hellström-Lindahl, Ewa; Danielsson, Angelika; Pontén, Fredrik; Czernichow, Paul et al.

Ingår i Acta Diabetologica, s. 413-421, 2016

• DOI för GPR44 is a pancreatic protein restricted to the human beta cell

Identification of proliferative and mature beta-cells in the islets of Langerhans

Bader, Erik; Migliorini, Adriana; Gegg, Moritz; Moruzzi, Noah et al.

Ingår i Nature, s. 430-+, 2016

• DOI för Identification of proliferative and mature beta-cells in the islets of Langerhans

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Krogvold, Lars; Wiberg, Anna; Edwin, Bjørn; Buanes, Trond et al.

Ingår i Diabetologia, s. 492-501, 2016

• DOI för Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

Ricordi, Camillo; Goldstein, Julia S.; Balamurugan, A. N.; Szot, Gregory L. et al.

Ingår i Diabetes, s. 3418-3428, 2016

• DOI för National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Eriksson, Olof et al.

Ingår i Diabetologia, s. 1968-1972, 2016

• DOI för Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Hering, Bernhard J.; Clarke, William R.; Bridges, Nancy D.; Eggerman, Thomas L. et al.

Ingår i Diabetes Care, s. 1230-1240, 2016

• DOI för Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Positron Emission Tomography to assess the outcome of intraportal islet transplantation

Eriksson, Olof; Selvaraju, Ramkumar; Eich, Torsten; Willny, Mariam et al.

Ingår i Diabetes, s. 2482-2489, 2016

• DOI för Positron Emission Tomography to assess the outcome of intraportal islet transplantation

Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement

Bartlett, Stephen T.; Markmann, James F.; Johnson, Paul; Korsgren, Olle et al.

Ingår i Transplantation, 2016

• DOI för Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement
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Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids

Kloster-Jensen, Kristine; Sahraoui, Afaf; Vethe, Nils Tore; Korsgren, Olle et al.

Ingår i Journal of Diabetes Research, 2016

• DOI för Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids
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Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

Davies, Lindsay C.; Alm, Jessica J.; Heldring, Nina; Moll, Guido et al.

Ingår i Stem Cells Translational Medicine, s. 1485-1495, 2016

• DOI för Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

A novel model for studies of blood-mediated long-term responses to cellular transplants

Hårdstedt, Maria; Lindblom, Susanne; Hong, Jaan; Nilsson, Bo et al.

Ingår i Upsala Journal of Medical Sciences, s. 28-39, 2015

• DOI för A novel model for studies of blood-mediated long-term responses to cellular transplants