Patrick Mickes publikationer

Ageing promotes metastasis via activation of the integrated stress response

Patel, Angana A. H.; Dzanan, Jozefina J.; Ali, Kevin X.; Eklund, Ella A. et al.

Ingår i Nature, 2026

• DOI för Ageing promotes metastasis via activation of the integrated stress response
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An Intelligent Differential Capacitive Bioelectronic Sensing System for Reliable Microfluidic Reagent Delivery in Automated Pathology

Kabashkin, Igor; Krainukovs, Aleksandrs; Pasicniks, Dmitrijs; Gercevs, Ivans et al.

Ingår i Electronics, 2026

• DOI för An Intelligent Differential Capacitive Bioelectronic Sensing System for Reliable Microfluidic Reagent Delivery in Automated Pathology
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Composite proteomic and metabolomic plasma biomarkers for detection of colorectal, lung and ovarian cancers

Åkerrén Ögren, Jim; Ekström, Joakim; Rameika, Natallia; Torell, Emma et al.

Ingår i Molecular Cancer, 2026

• DOI för Composite proteomic and metabolomic plasma biomarkers for detection of colorectal, lung and ovarian cancers
• Ladda ner fulltext (pdf) av Composite proteomic and metabolomic plasma biomarkers for detection of colorectal, lung and ovarian cancers

Design of a Modular Cyber-Physical Architecture for Multiplex Histological Staining

Kabashkin, Igor; Krainukovs, Aleksandrs; Pasicniks, Dmitrijs; Gercevs, Ivans et al.

Ingår i Applied Sciences, 2026

• DOI för Design of a Modular Cyber-Physical Architecture for Multiplex Histological Staining
• Ladda ner fulltext (pdf) av Design of a Modular Cyber-Physical Architecture for Multiplex Histological Staining

In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC

Lindberg, Amanda; Hellberg, Louise; Grandon, Anaïs; Yu, Hui et al.

Ingår i Cell Communication and Signaling, 2026

• DOI för In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
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Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer

Nordling, Love; Backman, Max; Mezheyeuski, Artur; Lindblad, Joakim et al.

Ingår i Lung Cancer, 2026

• DOI för Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer
• Ladda ner fulltext (pdf) av Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer

Left behind but not left alone: Excluded cell populations in the non-small cell lung cancer stroma predict superior long-term overall survival

Marwitz, Sebastian; Brunnstrom, Hans; Gulyas, Miklos; Botling, Johan et al.

Ingår i European Journal of Cancer, 2026

• DOI för Left behind but not left alone: Excluded cell populations in the non-small cell lung cancer stroma predict superior long-term overall survival

Spatially resolved T cell receptor diversity mapping uncovers of the cancer immune microenvironment

Magoulopoulou, Anastasia; Chatzinikolaou, Maria; Metousis, Andreas; Hu, Taobo et al.

Ingår i eBioMedicine, 2026

• DOI för Spatially resolved T cell receptor diversity mapping uncovers of the cancer immune microenvironment
• Ladda ner fulltext (pdf) av Spatially resolved T cell receptor diversity mapping uncovers of the cancer immune microenvironment

Vascular leakage in non-small cell lung cancer is associated with immune evasion and poor response to immunotherapy

Nwadozi, Emmanuel; Strell, Carina; Nordling, Sofia; Lindberg, Amanda et al.

Ingår i Cancer Letters, 2026

• DOI för Vascular leakage in non-small cell lung cancer is associated with immune evasion and poor response to immunotherapy
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Gene expression-based identification of prognostic markers in lung adenocarcinoma

Salomonsson, Annette; Ehinger, Daniel; Jonsson, Mats; Botling, Johan et al.

Ingår i PLOS ONE, 2025

• DOI för Gene expression-based identification of prognostic markers in lung adenocarcinoma
• Ladda ner fulltext (pdf) av Gene expression-based identification of prognostic markers in lung adenocarcinoma

In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC

Lindberg, Amanda; Muhl, Lars; Yu, Hui; Hellberg, Louise et al.

Ingår i Journal of Thoracic Oncology, s. 625-640, 2025

• DOI för In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC
• Ladda ner fulltext (pdf) av In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC

Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study

Broström, Erika; Isaksson, Johan; Xanthoulis, Panagiotis; Börjesson, Rebecka et al.

Ingår i Translational Lung Cancer Research, s. 1972-1985, 2025

• DOI för Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study
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Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma

Biswas, Dhruva; Liu, Yun-Hsin; Herrero, Javier; Wu, Yin et al.

Ingår i Nature Cancer, s. 86-101, 2025

• DOI för Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma
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scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples

Yadav, Ram Prakash; Xing, Pengwei; Zhao, Miao; Hollander, Peter et al.

Ingår i Nature Communications, 2025

• DOI för scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples
• Ladda ner fulltext (pdf) av scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples

Spatial distribution of tertiary lymphoid structures in the molecular and clinical context of non-small cell lung cancer.

Elfving, Hedvig; Yu, Hui; Kassete Fessehatsio, Kaleab; Brunnström, Hans et al.

Ingår i Cellular Oncology, s. 801-808, 2025

• DOI för Spatial distribution of tertiary lymphoid structures in the molecular and clinical context of non-small cell lung cancer.
• Ladda ner fulltext (pdf) av Spatial distribution of tertiary lymphoid structures in the molecular and clinical context of non-small cell lung cancer.

Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer

Yu, Hui; Magoulopoulou, Anastasia; Amini, Rose-Marie; Chatzinikolaou, Maria Paraskevi et al.

Ingår i Journal for ImmunoTherapy of Cancer, 2025

• DOI för Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer
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The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Ingår i Cell Death and Differentiation, s. 1915-1929, 2025

• DOI för The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
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Tumoral pSMAD2 as a prognostic biomarker in early-stage breast cancer: insights from the randomized SweBCG91RT trial

Tullberg, Axel Stenmark; Thurfjell, Viktoria; Kovacs, Aniko; Micke, Patrick et al.

Ingår i Breast Cancer Research and Treatment, s. 499-509, 2025

• DOI för Tumoral pSMAD2 as a prognostic biomarker in early-stage breast cancer: insights from the randomized SweBCG91RT trial
• Ladda ner fulltext (pdf) av Tumoral pSMAD2 as a prognostic biomarker in early-stage breast cancer: insights from the randomized SweBCG91RT trial

Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation

Maravelia, Panagiota; Yao, Haidong; Cai, Curtis; Silva, Daniela Nascimento et al.

Ingår i Gut, s. 1125-1136, 2025

• DOI för Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
• Ladda ner fulltext (pdf) av Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation

Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases

Malmros, Karina; Lindholm, Andreas; Vidarsdottir, Halla; Jirström, Karin et al.

Ingår i Virchows Archiv, s. 347-357, 2024

• DOI för Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases
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Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma

Enokido, Takayoshi; Horie, Masafumi; Yoshino, Seiko; Suzuki, Hiroshi I. et al.

Ingår i Molecular Cancer Research, s. 29-40, 2024

• DOI för Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma

The histological growth patterns in liver metastases from colorectal cancer display differences in lymphoid, myeloid, and mesenchymal cells

Garcia-Vicien, Gemma; Ruiz, Nuria; Micke, Patrick; Ruffinelli, Jose Carlos et al.

Ingår i MEDCOMM, 2024

• DOI för The histological growth patterns in liver metastases from colorectal cancer display differences in lymphoid, myeloid, and mesenchymal cells
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Tumor Heterogeneity Confounds Lymphocyte Metrics in Diagnostic Lung Cancer Biopsies

Elfving, Hedvig; Thurfjell, Viktoria; Mattsson, Johanna Sofia Margareta; Backman, Max et al.

Ingår i Archives of Pathology & Laboratory Medicine, 2024

• DOI för Tumor Heterogeneity Confounds Lymphocyte Metrics in Diagnostic Lung Cancer Biopsies
• Ladda ner fulltext (pdf) av Tumor Heterogeneity Confounds Lymphocyte Metrics in Diagnostic Lung Cancer Biopsies

Use of beta-blockers in patients with ductal carcinoma in situ and risk of invasive breast cancer recurrence: a Swedish retrospective cohort study

Strell, Carina; Smith, Daniel Robert; Valachis, Antonis; Woldeyesus, Hellen et al.

Ingår i Breast Cancer Research and Treatment, s. 293-299, 2024

• DOI för Use of beta-blockers in patients with ductal carcinoma in situ and risk of invasive breast cancer recurrence: a Swedish retrospective cohort study
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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, Artur; Backman, Max; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Ingår i eBioMedicine, 2023

• DOI för An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
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Expression of cancer-testis antigens in the immune microenvironment of non-small cell lung cancer

Hikmet Noraddin, Feria; Rassy, Marc; Backman, Max; Méar, Loren et al.

Ingår i Molecular Oncology, s. 2603-2617, 2023

• DOI för Expression of cancer-testis antigens in the immune microenvironment of non-small cell lung cancer
• Ladda ner fulltext (pdf) av Expression of cancer-testis antigens in the immune microenvironment of non-small cell lung cancer

Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features

Pellinen, Teijo; Paavolainen, Lassi; Martín-Bernabé, Alfonso; Papatella Araujo, Renata et al.

Ingår i Journal of the National Cancer Institute, s. 71-82, 2023

• DOI för Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features
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Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature

Tsakonas, Georgios; Koulouris, Andreas; Kazmierczak, Dominika; Botling, Johan et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature
• Ladda ner fulltext (pdf) av Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature

Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Gerdtsson, Anna Sandström; Knulst, Mattis; Botling, Johan; Mezheyeuski, Artur et al.

Ingår i Oncoimmunology, 2023

• DOI för Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer
• Ladda ner fulltext (pdf) av Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna S. M. et al.

Ingår i European Journal of Cancer, s. 40-52, 2023

• DOI för Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
• Ladda ner fulltext (pdf) av Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Harryvan, T.J.; Hawinkels, L.J.A.C.; Inderson, A.; van Hooft, J.E. et al.

Ingår i Gastro Hep Advances, s. 678-681, 2022

• DOI för A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation
• Ladda ner fulltext (pdf) av A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas

Thurfjell, Viktoria; Micke, Patrick; Yu, Hui; Krupar, Rosemarie et al.

Ingår i Translational Lung Cancer Research, s. 2477-2494, 2022

• DOI för Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas
• Ladda ner fulltext (pdf) av Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas

Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines

Ericson Lindquist, Kajsa; Ciornei, Cristina; Westbom-Fremer, Sofia; Gudinaviciene, Inga et al.

Ingår i Journal of Clinical Pathology, s. 302-309, 2022

• DOI för Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines
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Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Papadakos, Konstantinos S.; Lundgren, Sebastian; Gialeli, Chrysostomi; Micke, Patrick et al.

Ingår i Oncoimmunology, 2022

• DOI för Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion
• Ladda ner fulltext (pdf) av Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer

Isaksson, Johan; Wennström, Leo; Brandén, Eva; Koyi, Hirsh et al.

Ingår i Cancer Treatment and Research Communications, 2022

• DOI för Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer
• Ladda ner fulltext (pdf) av Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer

Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma

Khadse, Anand; Haakensen, Vilde D.; Silwal-Pandit, Laxmi; Hamfjord, Julian et al.

Ingår i Frontiers in Oncology, 2022

• DOI för Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma
• Ladda ner fulltext (pdf) av Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma

Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern

Garcia-Vicien, Gemma; Mezheyeuski, Artur; Micke, Patrick; Ruiz, Nuria et al.

Ingår i Cancers, 2022

• DOI för Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern
• Ladda ner fulltext (pdf) av Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern

Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial

Schiza, Aglaia; Thurfjell, Viktoria; Stenmark Tullberg, Axel; Olofsson, Helena et al.

Ingår i European Journal of Cancer, s. 128-137, 2022

• DOI för Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial
• Ladda ner fulltext (pdf) av Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation

Sabatier, Pierre; Beusch, Christian M.; Saei, Amir A.; Aoun, Mike et al.

Ingår i Nature Communications, 2021

• DOI för An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
• Ladda ner fulltext (pdf) av An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation

Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer

Elfving, Hedvig; Broström, Erika; Moens, Lotte N.J.; Almlöf, Jonas et al.

Ingår i Lung Cancer, s. 53-59, 2021

• DOI för Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer

FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response

Bogatyrova, Olga; Mattsson, Johanna S M; Ross, Edith M.; Sanderson, Michael P. et al.

Ingår i European Journal of Cancer, s. 136-149, 2021

• DOI för FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response
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High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

Tsakonas, Georgios; Martin-Bernabe, Alfonso; Rounis, Konstantinos; Moreno-Ruiz, Pablo et al.

Ingår i Cancers, 2021

• DOI för High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC
• Ladda ner fulltext (pdf) av High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Doffe, Flora; Carbonnier, Vincent; Tissier, Manon; Leroy, Bernard et al.

Ingår i Cell Death and Differentiation, s. 1477-1492, 2021

• DOI för Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene
• Ladda ner fulltext (pdf) av Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Ingår i Journal of Pathology, s. 243-256, 2021

• DOI för Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
• Ladda ner fulltext (pdf) av Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung

Goldmann, Torsten; Marwitz, Sebastian; Nitschkowski, Dorte; Krupar, Rosemarie et al.

Ingår i Cancer Immunology and Immunotherapy, s. 2577-2587, 2021

• DOI för PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung
• Ladda ner fulltext (pdf) av PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung

Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection

Bauer, Wolfgang; Weber, Marcus; Diehl-Wiesenecker, Eva; Galtung, Noa et al.

Ingår i Viruses, 2021

• DOI för Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection
• Ladda ner fulltext (pdf) av Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection

Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Eltahir, Mohamed; Isaksson, Johan; Mattsson, Johanna Sofia Margareta; Karre, Klas et al.

Ingår i Cancers, 2021

• DOI för Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade
• Ladda ner fulltext (pdf) av Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

Yu, Hui; Brustugun, Odd Terje; Ekman, Simon; Botling, Johan et al.

Ingår i Clinical Lung Cancer, s. 555-562, 2021

• DOI för Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation

Moreno-Ruiz, Pablo; Corvigno, Sara; te Grootenhuis, Nienke C.; La Fleur, Linnéa et al.

Ingår i Lung Cancer, s. 10-19, 2021

• DOI för Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation
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Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis

Yamaguchi, Yoko; Saito, Akira; Horie, Masafumi; Aoki, Akira et al.

Ingår i Odontology, s. 912-920, 2021

• DOI för Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis
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Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

La Fleur, Linnea; Botling, Johan; He, Fei; Pelicano, Catarina et al.

Ingår i Cancer Research, s. 956-967, 2021

• DOI för Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma

Miyashita, Naoya; Enokido, Takayoshi; Horie, Masafumi; Fukuda, Kensuke et al.

Ingår i Scientific Reports, 2021

• DOI för TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma
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The Immune Landscape of Colorectal Cancer

Mezheyeuski, Artur; Micke, Patrick; Martin-Bernabe, Alfonso; Backman, Max et al.

Ingår i Cancers, 2021

• DOI för The Immune Landscape of Colorectal Cancer
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The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, Patrick; Strell, Carina; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Ingår i eBioMedicine, 2021

• DOI för The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
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An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

Tsakonas, Georgios; Lewensohn, Rolf; Botling, Johan; Ortiz-Villalon, Cristian et al.

Ingår i European Journal of Cancer, s. 24-34, 2020

• DOI för An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer
• Ladda ner fulltext (pdf) av An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

Miyashita, Naoya; Horie, Masafumi; Mikami, Yu; Urushiyama, Hirokazu et al.

Ingår i Cancer Letters, s. 121-132, 2020

• DOI för ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer

Salomonsson, Annette; Micke, Patrick; Mattsson, Johanna S M; La Fleur, Linnéa et al.

Ingår i Cancer Medicine, s. 5609-5619, 2020

• DOI för Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer
• Ladda ner fulltext (pdf) av Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer

Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature

Staaf, Johan; Tran, Lena; Söderlund, Linnea; Nodin, Björn et al.

Ingår i Archives of Pathology & Laboratory Medicine, s. 1075-1085, 2020

• DOI för Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature

PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3

Ali, Abir Salwa; Langer, Seppo W.; Federspiel, Birgitte; Hjortland, Geir Olav et al.

Ingår i PLOS ONE, 2020

• DOI för PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3
• Ladda ner fulltext (pdf) av PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3

Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis

Kramer, Frederike; Dernedde, Jens; Mezheyeuski, Artur; Tauber, Rudolf et al.

Ingår i Haematologica, s. 2083-2094, 2020

• DOI för Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis
• Ladda ner fulltext (pdf) av Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis

Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma

Lundgren, Sebastian; Elebro, Jacob; Heby, Margareta; Nodin, Björn et al.

Ingår i International Journal of Cancer, s. 3461-3473, 2020

• DOI för Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma
• Ladda ner fulltext (pdf) av Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma

The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

Spiegelberg, Diana; Lundgren Mortensen, Anja Charlotte; Palupi, Kartika Dyah; Micke, Patrick et al.

Ingår i Frontiers in Oncology, 2020

• DOI för The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model
• Ladda ner fulltext (pdf) av The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

The protein expression profile of ACE2 in human tissues

Noraddin, Feria Hikmet; Méar, Loren; Edvinsson, Åsa; Micke, Patrick et al.

Ingår i Molecular Systems Biology, 2020

• DOI för The protein expression profile of ACE2 in human tissues

Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma

Lundgren, Sebastian; Micke, Patrick; Elebro, Jacob; Heby, Margareta et al.

Ingår i Frontiers in Immunology, 2020

• DOI för Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma
• Ladda ner fulltext (pdf) av Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma

A clonal expression biomarker associates with lung cancer mortality

Biswas, Dhruva; Birkbak, Nicolai J.; Rosenthal, Rachel; Hiley, Crispin T. et al.

Ingår i Nature Medicine, s. 1540-1548, 2019

• DOI för A clonal expression biomarker associates with lung cancer mortality

A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer

Karlsson, Anna; Cirenajwis, Helena; Ericson-Lindquist, Kajsa; Brunnström, Hans et al.

Ingår i Scientific Reports, 2019

• DOI för A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer
• Ladda ner fulltext (pdf) av A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer

Cancer stemness, intratumoral heterogeneity, and immune response across cancers

Miranda, Alex; Hamilton, Phineas T.; Zhang, Allen W.; Pattnaik, Swetansu et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 9020-9029, 2019

• DOI för Cancer stemness, intratumoral heterogeneity, and immune response across cancers

c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

Tsakonas, Georgios; Botling, Johan; Micke, Patrick; Rivard, Chris et al.

Ingår i Lung Cancer, s. 69-74, 2019

• DOI för c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases

Vidarsdottir, Halla; Tran, Lena; Nodin, Björn; Jirström, Karin et al.

Ingår i Human Pathology, s. 221-230, 2019

• DOI för Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, Cristina; Vosbeck, Sonja; Edlund, Karolina; Grgas, Katharina et al.

Ingår i International Journal of Cancer, s. 901-915, 2019

• DOI för LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
• Ladda ner fulltext (pdf) av LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer

Micke, Patrick; Botling, Johan; Mattsson, Johanna Sofia Margareta; Planck, Maria et al.

Ingår i Scientific Reports, 2019

• DOI för Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer
• Ladda ner fulltext (pdf) av Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer

Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

Djureinovic, Dijana; Pontén, Victor; Landelius, Per; Al Sayegh, Sahar et al.

Ingår i BMC Cancer, 2019

• DOI för Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung
• Ladda ner fulltext (pdf) av Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11

La Fleur, Linnea; Falk-Sörqvist, Elin; Smeds, Patrik; Berglund, Anders et al.

Ingår i Lung Cancer, s. 50-58, 2019

• DOI för Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11
• Ladda ner fulltext (pdf) av Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11

NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy

Sottile, Rosa; Tannazi, Milad; Johansson, Maria H.; Cristiani, Costanza Maria et al.

Ingår i International Journal of Cancer, s. 2238-2248, 2019

• DOI för NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Edlund, Karolina; Madjar, Katrin; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana et al.

Ingår i Journal of Thoracic Oncology, s. 628-640, 2019

• DOI för Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
• Ladda ner fulltext (pdf) av Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray

Elfving, Hedvig; Mattsson, Johanna Sofia Margareta; Lindskog, Cecilia; Backman, Max et al.

Ingår i Clinical Lung Cancer, s. 258-2620, 2019

• DOI för Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray

Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non small-cell lung cancer: The global, multicenter EXPRESS study

Dietel, M.; Savelov, N.; Salanova, R.; Micke, Patrick et al.

Ingår i Lung Cancer, s. 174-179, 2019

• DOI för Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non small-cell lung cancer: The global, multicenter EXPRESS study

30O Real-world prevalence of PD-L1 expression in locally advanced or metastatic non-small cell lung cancer (NSCLC): The global, multicentre EXPRESS study

Dietel, M.; Savelov, N.; Salanova, R.; Micke, Patrick et al.

Ingår i Journal of Thoracic Oncology, 2018

• DOI för 30O Real-world prevalence of PD-L1 expression in locally advanced or metastatic non-small cell lung cancer (NSCLC): The global, multicentre EXPRESS study

An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas

Miyashita, Naoya; Horie, Masafumi; Suzuki, Hiroshi I.; Yoshihara, Masahito et al.

Ingår i Journal of Thoracic Oncology, s. 1676-1691, 2018

• DOI för An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas

An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Horie, Masafumi; Miyashita, Naoya; Mattsson, Johanna Sofia Margareta; Mikami, Yu et al.

Ingår i Journal of Pathology, s. 154-165, 2018

• DOI för An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase

Vidarsdottir, Halla; Tran, Lena; Nodin, Björn; Jirström, Karin et al.

Ingår i American Journal of Clinical Pathology, s. 533-544, 2018

• DOI för Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase

COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Gulyas, Miklos; Mattsson, Johanna Sofia Margareta; Lindgren, Andrea; Ek, Lars et al.

Ingår i Acta Oncologica, s. 244-250, 2018

• DOI för COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Djureinovic, Dijana; Dodig-Crnkovic, Tea; Hellström, Cecilia; Holgersson, Georg et al.

Ingår i Lung Cancer, s. 157-163, 2018

• DOI för Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Digital multiplex immunofluorescence analysis identifies immune profiles in the tumor stroma associated with clinical outcome

Mezheyeuski, Artur; Bergsland, Christian; Backman, Max; Sjöblom, Tobias et al.

Ingår i CANCER IMMUNOLOGY RESEARCH, 2018

• DOI för Digital multiplex immunofluorescence analysis identifies immune profiles in the tumor stroma associated with clinical outcome

Digital pathology 2.0: a deep learning image analysis tool to identify lung cancer in human tissue samples

Micke, Patrick; Björk, L.; Backman, M.; Elfving, H. et al.

Ingår i Virchows Archiv, 2018

Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

La Fleur, Linnea; Boura, Vanessa F.; Alexeyenko, Andrey; Berglund, Anders et al.

Ingår i International Journal of Cancer, s. 1741-1752, 2018

• DOI för Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease

Karlsson, Terese; Kvarnbrink, Samuel; Holmlund, Camilla; Botling, Johan et al.

Ingår i Lung Cancer, s. 174-184, 2018

• DOI för LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease

Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients

Mezheyeuski, Artur; Bergsland, Christian Holst; Backman, Max; Djureinovic, Dijana et al.

Ingår i Journal of Pathology, s. 421-431, 2018

• DOI för Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Westerlund, Kristina; Altai, Mohamed; Mitran, Bogdan; Konijnenberg, Mark et al.

Ingår i Journal of Nuclear Medicine, s. 1092-1098, 2018

• DOI för Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Real-World Prevalence of PD-L1 Expression in Advanced NoneSmall-Cell Lung Cancer: The Global, Multicenter EXPRESS Study

Salanova, R.; Dietel, M.; Savelov, N.; Micke, Patrick et al.

Ingår i Journal of Thoracic Oncology, 2018

The Heidelberg compact electron beam ion traps

Micke, Patrick; Kühn, S; Buchauer, L; Harries, J R et al.

Ingår i Review of Scientific Instruments, 2018

• DOI för The Heidelberg compact electron beam ion traps

The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis

Saito, Akira; Horie, Masafumi; Micke, Patrick; Nagase, Takahide

Ingår i International Journal of Molecular Sciences, 2018

• DOI för The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis
• Ladda ner fulltext (pdf) av The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis

A pathology atlas of the human cancer transcriptome

Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina et al.

Ingår i Science, 2017

• DOI för A pathology atlas of the human cancer transcriptome

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Sandelin, Martin; Gruden, S.; Räsänen, Veera; Micke, Patrick et al.

Ingår i Annals of Oncology, 2017

• DOI för Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Grudén, Stefan; Sandelin, Martin; Rasanen, Veera; Micke, Patrick et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 186-193, 2017

• DOI för Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel
• Ladda ner fulltext (pdf) av Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Establishing Reflex NGS Testing in NSCLC in a Regional Network of County Hospitals in Central Sweden

Isaksson, Johan; Willen, Linda; La Fleur, Linnea; Mindus, Stephanie et al.

Ingår i Journal of Thoracic Oncology, 2017

• DOI för Establishing Reflex NGS Testing in NSCLC in a Regional Network of County Hospitals in Central Sweden

Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification

Karlsson, Anna; Brunnström, Hans; Micke, Patrick; Veerla, Srinivas et al.

Ingår i Journal of Thoracic Oncology, s. 1257-1267, 2017

• DOI för Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification
• Ladda ner fulltext (pdf) av Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification

Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer

Jabs, Verena; Edlund, Karolina; Koenig, Helena; Grinberg, Marianna et al.

Ingår i PLOS ONE, 2017

• DOI för Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer
• Ladda ner fulltext (pdf) av Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer

Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Horie, Masafumi; Kaczkowski, Bogumil; Ohshima, Mitsuhiro; Matsuzaki, Hirotaka et al.

Ingår i Molecular Cancer Research, s. 1354-1365, 2017

• DOI för Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Mutation Profiling by Targeted Next Generation Sequencing of an Unselected NSCLC Cohort

La Fleur, Linnea; Falk-Sörqvist, Elin; Smeds, Patrik; Sundström, Magnus et al.

Ingår i Journal of Thoracic Oncology, 2017

• DOI för Mutation Profiling by Targeted Next Generation Sequencing of an Unselected NSCLC Cohort