Rudbeckseminarium - Claudia Kutter

Short bio:

Claudia Kutter is a Principal Researcher and Group Leader at Karolinska Institutet and SciLifeLab in Stockholm, Sweden. She received her PhD from the University of Basel following research at the Friedrich Miescher Institute in Switzerland, where she investigated the role of microRNAs in stem cell differentiation. She subsequently joined Cancer Research UK and the University of Cambridge as a postdoctoral researcher, where she studied the evolution and genome-wide regulation of non-coding RNAs and regulatory sequences in mammals. In 2016, she joint the Karolinska Institute as a SciLifeLab and Wallenberg Fellow. Her research focuses on how coding and non-coding genomic elements coordinate gene regulation and how these mechanisms are disrupted in disease. Her lab combines experimental and computational multi-omics to study post-transcriptional regulation, particularly in liver disease and cancer, with the aim of uncovering disease mechanisms and identifying new diagnostic and therapeutic opportunities.

Relevant literature:

Mosca R, Gallardo-Dodd C, Li Q, Sommerauer C, Šidiškis J, Søndergaard JN and Kutter C.

“RAPseq enables large-scale identification of RBP-RNA interactions and reveals essentials of post-transcriptional gene regulation”

Nucleic Acids Research (2026), 54(5):gkag090

Sommerauer C, Gallardo-Dodd CJ, Savva C, Hases L, Birgersson M, Indukuri R, Shen JX, Carravilla P, Geng K, Søndergaard JN, Ferrer-Aumatell C, Mercier G, Sezgin E, Korach-André M, Petersson C, Hagström H, Lauschke V, Archer A, Williams C and Kutter C.

“Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis”

Molecular Systems Biology (2024) 20 (4):374-402

Søndergaard JN, Sommerauer C, Atanasoai I, Hinte L, Geng K, Guiducci G, Bräutigam L, Aouadi M, Stojic L, Barragan I and Kutter C.

“CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism”

Gut (2022) 71(10):2081-92