Lena Claesson-Welsh – Vaskulärbiologi

Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Pal, Sagnik; Su, Yangyang; Nwadozi, Emmanuel; Claesson-Welsh, Lena et al.

Ingår i Angiogenesis, 2025

• DOI för Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
• Ladda ner fulltext (pdf) av Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Hypersensitive blood vessels in Clarkson disease

Nwadozi, Emmanuel; Claesson-Welsh, Lena

Ingår i Journal of Clinical Investigation, 2024

• DOI för Hypersensitive blood vessels in Clarkson disease
• Ladda ner fulltext (pdf) av Hypersensitive blood vessels in Clarkson disease

TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Shan, Ke Zoe; Le, Trieu; Liang, Pengfei; Dong, Ping et al.

Ingår i Journal of Cell Science, 2024

• DOI för TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis

Sáinz-Jaspeado, Miguel; Ring, Sarah; Proulx, Steven T.; Richards, Mark et al.

Ingår i Life Science Alliance, 2024

• DOI för VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
• Ladda ner fulltext (pdf) av VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis

CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin

Lugano, Roberta; Vemuri, Kalyani; Barbera, Stefano; Orlandini, Maurizio et al.

Ingår i The FASEB Journal, 2023

• DOI för CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin
• Ladda ner fulltext (pdf) av CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin

Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption

Zarkada, Georgia; Chen, Xun; Zhou, Xuetong; Lange, Martin et al.

Ingår i Circulation Research, s. 333-349, 2023

• DOI för Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption

Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src

Sjöberg, Elin; Melssen, Marit; Richards, Mark; Ding, Yindi et al.

Ingår i Journal of Clinical Investigation, 2023

• DOI för Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src
• Ladda ner fulltext (pdf) av Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src

Report from the 2023 workshop on endothelial permeability, edema and inflammation

Vestweber, Dietmar; Claesson-Welsh, Lena; McDonald, Donald M.; Williams, Timothy et al.

Ingår i Nature Cardiovascular Research, s. 1120-1124, 2023

• DOI för Report from the 2023 workshop on endothelial permeability, edema and inflammation

Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Richards, Mark; Nwadozi, Emmanuel; Pal, Sagnik; Martinsson, Pernilla et al.

Ingår i eLIFE, 2022

• DOI för Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
• Ladda ner fulltext (pdf) av Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Endothelial Unc5B controls blood-brain barrier integrity

Boye, Kevin; Geraldo, Luiz Henrique; Furtado, Jessica; Pibouin-Fragner, Laurence et al.

Ingår i Nature Communications, 2022

• DOI för Endothelial Unc5B controls blood-brain barrier integrity
• Ladda ner fulltext (pdf) av Endothelial Unc5B controls blood-brain barrier integrity

p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin

Maeso-Alonso, Laura; Alonso-Olivares, Hugo; Martinez-Garcia, Nicole; Lopez-Ferreras, Lorena et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2022

• DOI för p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin
• Ladda ner fulltext (pdf) av p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin

Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

Persson Skare, Tor; Kaito, Hiroshi; Durall, Claudia; Aastrup, Teodor et al.

Ingår i Cells, 2022

• DOI för Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells
• Ladda ner fulltext (pdf) av Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

Zhou, Weibin; Liu, Keli; Zeng, Lei; He, Jiaqi et al.

Ingår i Circulation, s. 1855-1881, 2022

• DOI för Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

Targeting VEGF-induced vascular permeability

Richards, Mark; Claesson-Welsh, Lena

Ingår i Nature Cardiovascular Research, s. 413-414, 2022

• DOI för Targeting VEGF-induced vascular permeability

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Ingår i Nature Cardiovascular Research, s. 1156-1173, 2022

• DOI för Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
• Ladda ner fulltext (pdf) av Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Tyrosine-protein kinase Yes is essential in vascular barrier dynamics

Claesson-Welsh, Lena; Jin, Yi

Ingår i Nature Cardiovascular Research, s. 1136-1137, 2022

• DOI för Tyrosine-protein kinase Yes is essential in vascular barrier dynamics

Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Vion, Anne-Clemence; Perovic, Tijana; Petit, Charlie; Hollfinger, Irene et al.

Ingår i Frontiers in Physiology, 2021

• DOI för Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways
• Ladda ner fulltext (pdf) av Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Ninchoji, Takeshi; Love, Dominic T.; Smith, Ross O.; Hedlund, Marie et al.

Ingår i eLIFE, 2021

• DOI för eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin
• Ladda ner fulltext (pdf) av eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin alpha 5

Richards, Mark; Pal, Sagnik; Sjöberg, Elin; Martinsson, Pernilla et al.

Ingår i Cell Reports, 2021

• DOI för Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin alpha 5

Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis

Nitzsche, Anja; Pietilä, Riikka; Love, Dominic T.; Testini, Chiara et al.

Ingår i EMBO Reports, 2021

• DOI för Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
• Ladda ner fulltext (pdf) av Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis

Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Sainz-Jaspeado, Miguel; Smith, Ross O.; Plunde, Oscar; Pawelzik, Sven-Christian et al.

Ingår i Circulation, s. 1629-1645, 2021

• DOI för Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium
• Ladda ner fulltext (pdf) av Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

Claesson-Welsh, Lena; Dejana, Elisabetta; McDonald, Donald M.

Ingår i Trends in Molecular Medicine, s. 314-331, 2021

• DOI för Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies
• Ladda ner fulltext (pdf) av Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

Stories in Molecular Medicine April 2021

Kavelaars, Annemieke; Claesson-Welsh, Lena; Culp-Hill, Rachel; Lothstein, Katherine et al.

Ingår i Trends in Molecular Medicine, s. 293-296, 2021

• DOI för Stories in Molecular Medicine April 2021

c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly

Schimmel, Lilian; Fukuhara, Daisuke; Richards, Mark; Jin, Yi et al.

Ingår i Development, 2020

• DOI för c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly
• Ladda ner fulltext (pdf) av c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly

House retinal cell behaviour in space and time using light sheet fluorescence microscopy

Prahst, Claudia; Ashrafzadeh, Parham; Mead, Thomas; Figueiredo, Ana et al.

Ingår i eLIFE, 2020

• DOI för House retinal cell behaviour in space and time using light sheet fluorescence microscopy
• Ladda ner fulltext (pdf) av House retinal cell behaviour in space and time using light sheet fluorescence microscopy

How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer: Comment

Claesson-Welsh, Lena

Ingår i Journal of Clinical Investigation, s. 1093-1095, 2020

• DOI för How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer: Comment

Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival

Persson Skare, Tor; Sjöberg, Elin; Berglund, Mattias; Smith, Ross O. et al.

Ingår i eJHaem, s. 199-207, 2020

• DOI för Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival
• Ladda ner fulltext (pdf) av Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival

Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer

Claesson-Welsh, Lena

Ingår i Upsala Journal of Medical Sciences, s. 205-210, 2020

• DOI för Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer
• Ladda ner fulltext (pdf) av Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer

Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma

Morin, Eric; Lindskog, Cecilia; Johansson, Martin; Egevad, Lars et al.

Ingår i Journal of Pathology, s. 387-396, 2020

• DOI för Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma
• Ladda ner fulltext (pdf) av Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma

Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction

Li, Xiujuan; Redfors, Bjorn; Sainz-Jaspeado, Miguel; Shi, Shujing et al.

Ingår i Frontiers in Physiology, 2020

• DOI för Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction
• Ladda ner fulltext (pdf) av Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction

Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin

Smith, Ross O.; Ninchoji, Takeshi; Gordon, Emma; Andre, Helder et al.

Ingår i eLIFE, 2020

• DOI för Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
• Ladda ner fulltext (pdf) av Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin

ATTRACT Arterial Flow as Attractor for Endothelial Cell Migration

Georgieva, Petya B.; Marchuk, Douglas A.; Gerhardt, Holger; Franco, Claudio A. et al.

Ingår i Circulation Research, s. 262-264, 2019

• DOI för ATTRACT Arterial Flow as Attractor for Endothelial Cell Migration

Caspase-8 modulates physiological and pathological angiogenesis during retina development

Tisch, Nathalie; Freire-Valls, Aida; Yerbes, Rosario; Paredes, Isidora et al.

Ingår i Journal of Clinical Investigation, s. 5092-5107, 2019

• DOI för Caspase-8 modulates physiological and pathological angiogenesis during retina development

Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

Corada, Monica; Orsenigo, Fabrizio; Bhat, Ganesh Parameshwar; Conze, Lei Liu et al.

Ingår i Circulation Research, s. 511-525, 2019

• DOI för Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier
• Ladda ner fulltext (pdf) av Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Testini, Chiara; Smith, Ross O.; Jin, Yi; Martinsson, Pernilla et al.

Ingår i EMBO Reports, 2019

• DOI för Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2
• Ladda ner fulltext (pdf) av Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

Ragunathrao, Vijay Avin Balaji; Anwar, Mumtaz; Akhter, Md Zahid; Chavez, Alejandra et al.

Ingår i Cell Reports, s. 3472-3487, 2019

• DOI för Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
• Ladda ner fulltext (pdf) av Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pietilä, Ilkka; van Mourik, Djenolan; Tamelander, Andreas; Kriz, Vitezslav et al.

Ingår i Cells, 2019

• DOI för Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB
• Ladda ner fulltext (pdf) av Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality

Claesson-Welsh, Lena

Ingår i EMBO Molecular Medicine, 2019

• DOI för What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality
• Ladda ner fulltext (pdf) av What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality

Alk1 (Activin Receptor-Like Kinase 1) and Vascular Hyperpermeability in Diabetic Retinopathy: More Is Less

Claesson-Welsh, Lena

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1673-1675, 2018

• DOI för Alk1 (Activin Receptor-Like Kinase 1) and Vascular Hyperpermeability in Diabetic Retinopathy: More Is Less

Cytokines regulating lymphangiogenesis

Sainz-Jaspeado, Miguel; Claesson-Welsh, Lena

Ingår i Current Opinion in Immunology, s. 58-63, 2018

• DOI för Cytokines regulating lymphangiogenesis

Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Honkura, Naoki; Richards, Mark; Laviña, Bàrbara; Sainz-Jaspeado, Miguel et al.

Ingår i Nature Communications, 2018

• DOI för Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events
• Ladda ner fulltext (pdf) av Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018

• DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
• Ladda ner fulltext (pdf) av Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Ingår i Theranostics, s. 4462-4476, 2018

• DOI för Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
• Ladda ner fulltext (pdf) av Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Shear Stress and VE-Cadherin: The Molecular Mechanism of Vascular Fusion

Caolo, Vincenza; Peacock, Hanna M.; Kasaai, Bahar; Swennen, Geertje et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2174-2183, 2018

• DOI för Shear Stress and VE-Cadherin: The Molecular Mechanism of Vascular Fusion

Shear stress, notch and VE-cadherin: the molecular mechanism of vascular fusion

Caolo, V.; Peacock, H. M.; Kasaai, B.; Swennen, G. et al.

Ingår i Cardiovascular Research, 2018

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Ingår i Acta Oncologica, s. 187-194, 2018

• DOI för U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
• Ladda ner fulltext (pdf) av U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Morin, Eric; Sjöberg, Elin; Tjomsland, Vegard; Testini, Chiara et al.

Ingår i Journal of Pathology, s. 311-322, 2018

• DOI för VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival
• Ladda ner fulltext (pdf) av VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan, Narendra; Yan, Junhong; Boge, Annegret; Scrivener, Elaine et al.

Ingår i Scientific Reports, 2017

• DOI för Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation
• Ladda ner fulltext (pdf) av Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model

Mitran, Bogdan; Guler, R.; Roche, Francis P.; Lindström, Elin et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Ingår i Oncotarget, s. 73200-73215, 2016

• DOI för Case-specific potentiation of glioblastoma drugs by pterostilbene

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Padhan, Narendra; Nordling, Torbjorn E. M.; Sundström, Magnus; Åkerud, Peter et al.

Ingår i BMC Cancer, 2016

• DOI för High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
• Ladda ner fulltext (pdf) av High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Mechanisms and regulation of endothelial VEGF receptor signalling

Simons, Michael; Gordon, Emma; Claesson-Welsh, Lena

Ingår i Nature reviews. Molecular cell biology, s. 611-625, 2016

• DOI för Mechanisms and regulation of endothelial VEGF receptor signalling

Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling

Fleetwood, Filippa; Guler, Rezan; Gordon, Emma; Stahl, Stefan et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 1671-1683, 2016

• DOI för Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling

The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Gordon, Emma J.; Fukuhara, Daisuke; Weström, Simone; Padhan, Narendra et al.

Ingår i Science Signaling, 2016

• DOI för The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns

Claesson-Welsh, Lena; Hansson, Goran K.

Ingår i The Lancet, s. 942-942, 2016

• DOI för Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns

VEGF receptor signal transduction - A brief update

Claesson-Welsh, Lena

Ingår i Vascular pharmacology, s. 14-17, 2016

• DOI för VEGF receptor signal transduction - A brief update

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Li, Xiujuan; Padhan, Narendra; Sjöström, Elisabet O.; Roche, Francis P. et al.

Ingår i Nature Communications, 2016

• DOI för VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
• Ladda ner fulltext (pdf) av VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with alpha 2 integrin

Roche, Francis; Sipilä, Kalle; Honjo, Satoshi; Staffan, Johansson et al.

Ingår i Matrix Biology, s. 89-99, 2015

• DOI för Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with alpha 2 integrin

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Ingår i Blood, s. 2016-2026, 2015

• DOI för Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

New Frontiers in VEGF/VEGFR Biology

Claesson-Welsh, Lena

Ingår i Journal of Vascular Research, s. 79-79, 2015

On the physiology of vascular permeability

Claesson-Welsh, Lena

Ingår i Acta Physiologica, s. 19-19, 2015

p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGF beta signaling

Fernandez-Alonso, R.; Martin-Lopez, M.; Gonzalez-Cano, L.; Garcia, S. et al.

Ingår i Cell Death and Differentiation, s. 1287-+, 2015

• DOI för p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGF beta signaling

Vascular permeability - the essentials

Claesson-Welsh, Lena

Ingår i Upsala Journal of Medical Sciences, s. 135-143, 2015

• DOI för Vascular permeability - the essentials

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet K.; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2014

Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.

Tugues, Sònia; Roche, Francis; Noguer, Oriol; Orlova, Anna et al.

Ingår i PLOS ONE, 2014

• DOI för Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.
• Ladda ner fulltext (pdf) av Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

Koch, Sina; van Meeteren, Laurens A.; Morin, Eric; Testini, Chiara et al.

Ingår i Developmental Cell, s. 633-646, 2014

• DOI för NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey et al.

Ingår i Circulation Research, s. 806-822, 2014

• DOI för Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

Bentley, Katie; Franco, Claudio Areias; Philippides, Andrew; Blanco, Raquel et al.

Ingår i Nature Cell Biology, s. 309-321, 2014

• DOI för The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2013

Hypoxia-Induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

Lanner, Fredrik; Lee, Kian Leong; Ortega, German C.; Sohl, Marcus et al.

Ingår i Stem Cells and Development, s. 1360-1369, 2013

• DOI för Hypoxia-Induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

Introduction to symposium on vascular biology, metabolism and cancer

Claesson-Welsh, Lena

Ingår i Journal of Internal Medicine, s. 112-113, 2013

• DOI för Introduction to symposium on vascular biology, metabolism and cancer

Introduction to the ECR special angiogenesis issue

Claesson-Welsh, Lena; Gerhardt, Holger

Ingår i Experimental Cell Research, s. 1239-1239, 2013

• DOI för Introduction to the ECR special angiogenesis issue

Pulmunary Lymphangiectasia Resulting From Vascular Endotelial Growth Factor-C Overexpression During a Critical Period

Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey et al.

Ingår i Circulation Research, 2013

Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-beta 1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo

Tugues, Sonia; Honjo, Satoshi; König, Christian; Padhan, Narendra et al.

Ingår i Journal of Biological Chemistry, s. 19060-19071, 2013

• DOI för Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-beta 1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo

The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013

VEGFA and tumour angiogenesis

Claesson-Welsh, Lena; Welsh, Michael

Ingår i Journal of Internal Medicine, s. 114-127, 2013

• DOI för VEGFA and tumour angiogenesis
• Ladda ner fulltext (pdf) av VEGFA and tumour angiogenesis

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Hayashi, Makoto; Majumdar, Arindam; Li, Xiujuan; Adler, Jeremy et al.

Ingår i Nature Communications, s. 1672, 2013

• DOI för VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Blood vessels as targets in tumor therapy

Claesson-Welsh, Lena

Ingår i Upsala Journal of Medical Sciences, s. 178-186, 2012

• DOI för Blood vessels as targets in tumor therapy

Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Le Jan, Sébastien; Hayashi, Makoto; Kasza, Zsolt; Eriksson, Inger et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1255-1263, 2012

• DOI för Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization

Tugues, Sònia; Honjo, Satoshi; König, Christian; Noguer, Oriol et al.

Ingår i Cancer Research, 2012

• DOI för Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization

Histidine-rich Glycoprotein Regulates Macrophage Differentiation

Noguer, Oriol; Tugues, Sonia; Honjo, Satoshi; Claesson-Welsh, Lena

Ingår i European Journal of Cancer, 2012

• DOI för Histidine-rich Glycoprotein Regulates Macrophage Differentiation

Receptor Talk and Tumor Cell Walk in Glioblastoma

Claesson-Welsh, Lena

Ingår i Cancer Cell, s. 1-2, 2012

• DOI för Receptor Talk and Tumor Cell Walk in Glioblastoma

Signal transduction by vascular endothelial growth factor receptors

Claesson-Welsh, Lena

Ingår i Vascular pharmacology, s. 308-308, 2012

• DOI för Signal transduction by vascular endothelial growth factor receptors

Signal transduction by vascular endothelial growth factor receptors

Koch, Sina; Claesson-Welsh, Lena

Ingår i Cold Spring Harbor Perspectives in Medicine, 2012

• DOI för Signal transduction by vascular endothelial growth factor receptors

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Sun, Zuyue; Li, Xiujuan; Massena, Sara; Kutschera, Simone et al.

Ingår i Journal of Experimental Medicine, s. 1363-1377, 2012

• DOI för VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

Rivera, Corban G.; Mellberg, Sofie; Claesson-Welsh, Lena; Bader, Joel S. et al.

Ingår i PLOS ONE, 2011

• DOI för Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

Rolny, Charlotte; Mazzone, Massimiliano; Tugues, Sònia; Laoui, Damya et al.

Ingår i Cancer Cell, s. 31-44, 2011

• DOI för HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

Signal transduction by vascular endothelial growth factor receptors

Koch, Sina; Tugues, Sonia; Li, Xiujuan; Gualandi, Laura et al.

Ingår i Biochemical Journal, s. 169-183, 2011

• DOI för Signal transduction by vascular endothelial growth factor receptors

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

Tugues, Sonia; Koch, Sina; Gualandi, Laura; Li, Xiujuan et al.

Ingår i Molecular Aspects of Medicine, s. 88-111, 2011

• DOI för Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

Geretti, Elena; van Meeteren, Laurens A.; Shimizu, Akio; Dudley, Andrew C. et al.

Ingår i Molecular Cancer Research, s. 1063-1073, 2010

• DOI för A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

ADAM-mediated shedding, a new flavor in angiogenesis regulation

Claesson-Welsh, Lena

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2087-2088, 2010

• DOI för ADAM-mediated shedding, a new flavor in angiogenesis regulation

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

Van de Veire, Sara; Stalmans, Ingeborg; Heindryckx, Femke; Oura, Hajimu et al.

Ingår i Cell, s. 178-190, 2010

• DOI för Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

Gremlin: vexing VEGF receptor agonist

Claesson-Welsh, Lena

Ingår i Blood, s. 3386-3387, 2010

• DOI för Gremlin: vexing VEGF receptor agonist

p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration

Li, Zhilun; Zhang, Hongquan; Lundin, Lars; Thullberg, Minna et al.

Ingår i Journal of Biological Chemistry, s. 23699-23710, 2010

• DOI för p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

Berge, Tone; Sundvold-Gjerstad, Vibeke; Granum, Stine; Andersen, Thorny C. et al.

Ingår i PloS one, 2010

• DOI för T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

Vascular endothelial growth factor B controls endothelial fatty acid uptake

Hagberg, Carolina E.; Falkevall, Annelie; Wang, Xun; Larsson, Erik et al.

Ingår i Nature, s. 917-921, 2010

• DOI för Vascular endothelial growth factor B controls endothelial fatty acid uptake

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

Nilsson, Ingrid; Bahram, Fuad; Li, Xiujuan; Gualandi, Laura et al.

Ingår i EMBO Journal, s. 1377-1388, 2010

• DOI för VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

VEGF-mediated signal transduction in lymphatic endothelial cells

Bahram, Fuad; Claesson-Welsh, Lena

Ingår i Pathophysiology : the official journal of the International Society for Pathophysiology / ISP, s. 253-261, 2010

• DOI för VEGF-mediated signal transduction in lymphatic endothelial cells

Distinct role of PLC{beta}3 in VEGF-mediated directional migration and vascular sprouting

Bhattacharya, Resham; Kwon, Junhye; Li, Xiujuan; Wang, Enfeng et al.

Ingår i Journal of Cell Science, s. 1025-1034, 2009

• DOI för Distinct role of PLC{beta}3 in VEGF-mediated directional migration and vascular sprouting

Embryonic stem cell models in vascular biology

Li, Xiujuan; Claesson-Welsh, Lena

Ingår i Journal of Thrombosis and Haemostasis, s. 53-56, 2009

• DOI för Embryonic stem cell models in vascular biology