Peetra Magnusson – Inflammation, trombos och ischemi i kärlbiologi

KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation

Arce, Maximiliano; Erzar, Iza; Yang, Fan; Senthilkumar, Neeharika et al.

Ingår i Cell Reports, 2025

• DOI för KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation
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BMI1 Inhibition Improves Lesion Burden in Cerebral Cavernous Malformations

Valentino, Mariaelena; Malinverno, Matteo; Maderna, Claudio; Pham, Van-Cuong et al.

Ingår i Circulation, s. 738-741, 2024

• DOI för BMI1 Inhibition Improves Lesion Burden in Cerebral Cavernous Malformations

Circulating biomarkers in familial cerebral cavernous malformation

Lazzaroni, Francesca; Meessen, Jennifer M. T. A.; Sun, Ying; Lanfranconi, Silvia et al.

Ingår i EBioMedicine, 2024

• DOI för Circulating biomarkers in familial cerebral cavernous malformation
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Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro

Selvarajan, Ilakya; Kiema, Miika; Huang, Ru-Ting; Li, Jin et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1330-1345, 2024

• DOI för Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro

Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations

Pham, Van-Cuong; Roedel, Claudia Jasmin; Valentino, Mariaelena; Malinverno, Matteo et al.

Ingår i EMBO Molecular Medicine, s. 2827-2855, 2024

• DOI för Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations
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Pharmacological blocking of neutrophil extracellular traps attenuates immunothrombosis and neuroinflammation in cerebral cavernous malformation

Onyeogaziri, Favour C.; Smith, Ross; Arce, Maximiliano; Huang, Hua et al.

Ingår i Nature Cardiovascular Research, s. 1549-1567, 2024

• DOI för Pharmacological blocking of neutrophil extracellular traps attenuates immunothrombosis and neuroinflammation in cerebral cavernous malformation
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Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology

Jauhiainen, Suvi; Onyeogaziri, Favour C.; Lazzaroni, Francesca; Liu Conze, Lei et al.

Ingår i Biochimica et Biophysica Acta - Molecular Basis of Disease, 2024

• DOI för Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology

Heparin Conjugate Pretreatment of Kidneys From Deceased Donors Before Transplantation: Results From the First-in-human Randomized Phase I Trial

Sedigh, Amir; Lundgren, Torbjörn; Lindnér, Per; Nordström, Johan et al.

Ingår i Transplantation direct, 2023

• DOI för Heparin Conjugate Pretreatment of Kidneys From Deceased Donors Before Transplantation: Results From the First-in-human Randomized Phase I Trial
• Ladda ner fulltext (pdf) av Heparin Conjugate Pretreatment of Kidneys From Deceased Donors Before Transplantation: Results From the First-in-human Randomized Phase I Trial

SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space

Beter, M.; Abdollahzadeh, A.; Pulkkinen, H. H.; Huang, Hua et al.

Ingår i Scientific Reports, 2023

• DOI för SproutAngio: an open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space
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Stromal transdifferentiation drives lipomatosis and induces extensive vascular remodeling in the aging human lymph node

Bekkhus, Tove; Olofsson, Anna; Sun, Ying; Magnusson, Peetra U. et al.

Ingår i Journal of Pathology, s. 236-253, 2023

• DOI för Stromal transdifferentiation drives lipomatosis and induces extensive vascular remodeling in the aging human lymph node
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Dysregulated Hemostasis and Immunothrombosis in Cerebral Cavernous Malformations

Globisch, Maria Ascencion; Onyeogaziri, Favour; Smith, Ross O.; Arce, Maximiliano et al.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Dysregulated Hemostasis and Immunothrombosis in Cerebral Cavernous Malformations
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Immunothrombosis and vascular heterogeneity in cerebral cavernous malformation

Globisch, Maria A.; Onyeogaziri, Favour C.; Jauhiainen, Suvi; Yau, Anthony C. Y. et al.

Ingår i Blood, s. 2154-2169, 2022

• DOI för Immunothrombosis and vascular heterogeneity in cerebral cavernous malformation
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Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

Yau, Anthony C. Y.; Globisch, Maria A.; Onyeogaziri, Favour; Conze, Lei Liu et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2022

• DOI för Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
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Inflammation and neutrophil extracellular traps in cerebral cavernous malformation (vol 79, 206, 2022)

Yau, Anthony C. Y.; Globisch, Maria A.; Onyeogaziri, Favour; Conze, Lei L. et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2022

• DOI för Inflammation and neutrophil extracellular traps in cerebral cavernous malformation (vol 79, 206, 2022)
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Slow-Closing Clip for the Treatment of Nonsaccular Vertebrobasilar Aneurysms: A Retrospective Case Series

Rezai Jahromi, Behnam; Dashti, Reza; Rustemi, Oriela; Silva, João M. et al.

Ingår i World Neurosurgery, 2022

• DOI för Slow-Closing Clip for the Treatment of Nonsaccular Vertebrobasilar Aneurysms: A Retrospective Case Series

Propranolol Reduces the Development of Lesions and Rescues Barrier Function in Cerebral Cavernous Malformations: A Preclinical Study

Oldenburg, Joppe; Malinverno, Matteo; Globisch, Maria A.; Maderna, Claudio et al.

Ingår i Stroke, s. 1418-1427, 2021

• DOI för Propranolol Reduces the Development of Lesions and Rescues Barrier Function in Cerebral Cavernous Malformations: A Preclinical Study

The blood endothelial cell chamber: an innovative system to study immune responses in drug development

Stancic, Brina; Qvarfordt, Bodil; Berglund, Magnus M.; Brenden, Nina et al.

Ingår i International Journal of Immunopharmacology, 2021

• DOI för The blood endothelial cell chamber: an innovative system to study immune responses in drug development
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Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/beta-catenin signaling

Cottarelli, Azzurra; Corada, Monica; Beznoussenko, Galina, V; Mironov, Alexander A. et al.

Ingår i Development, 2020

• DOI för Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/beta-catenin signaling

Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution

Orsenigo, Fabrizio; Conze, Lei Liu; Jauhiainen, Suvi; Corada, Monica et al.

Ingår i eLIFE, 2020

• DOI för Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution
• Ladda ner fulltext (pdf) av Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution

Endothelial cell clonal expansion in the development of cerebral cavernous malformations

Malinverno, Matteo; Maderna, Claudio; Abu Taha, Abdallah; Corada, Monica et al.

Ingår i Nature Communications, 2019

• DOI för Endothelial cell clonal expansion in the development of cerebral cavernous malformations
• Ladda ner fulltext (pdf) av Endothelial cell clonal expansion in the development of cerebral cavernous malformations

Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

Corada, Monica; Orsenigo, Fabrizio; Bhat, Ganesh Parameshwar; Conze, Lei Liu et al.

Ingår i Circulation Research, s. 511-525, 2019

• DOI för Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier
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Perfusion of Porcine Kidneys With Macromolecular Heparin Reduces Early Ischemia Reperfusion Injury

Sedigh, Amir; Nordling, Sofia; Carlsson, Fredrik; Larsson, Erik et al.

Ingår i Transplantation, s. 420-427, 2019

• DOI för Perfusion of Porcine Kidneys With Macromolecular Heparin Reduces Early Ischemia Reperfusion Injury

Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse

Nordling, Sofia; Brännström, Johan; Carlsson, Fredrik; Lu, Bo et al.

Ingår i Scientific Reports, 2018

• DOI för Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse
• Ladda ner fulltext (pdf) av Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse

Deregulated TGF-beta/BMP Signaling in Vascular Malformations

Cunha, Sara I.; Magnusson, Peetra; Dejana, Elisabetta; Lampugnani, Maria Grazia

Ingår i Circulation Research, s. 981-999, 2017

• DOI för Deregulated TGF-beta/BMP Signaling in Vascular Malformations

Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Bongoni, Anjan K.; Salvaris, Evelyn; Nordling, Sofia; Klymiuk, Nikolai et al.

Ingår i Scientific Reports, 2017

• DOI för Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood
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Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Nilsson Ekdahl, Kristina; Teramura, Yuji; Hamad, Osama A.; Asif, Sana et al.

Ingår i Immunological Reviews, s. 245-269, 2016

• DOI för Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man

Liu, Wei; Edin, Fredrik; Blom, Hans; Magnusson, Peetra et al.

Ingår i Cell and Tissue Research, s. 13-27, 2016

• DOI för Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man

Comparing PLGA and PLGA/Chitosan Nanofibers Seeded by Msc: A Cell-scaffold Interaction Study

Ajalloueian, F.; Fransson, M.; Tavanai, H.; Hilborn, Jöns et al.

Ingår i Tissue Engineering. Part A, 2015

Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria

Berg, Aase; Otterdal, Karl; Patel, Sam; Gonca, Miguel et al.

Ingår i The Internet Journal of Infectious Diseases, s. 1835-1840, 2015

• DOI för Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria

Investigation of Human Mesenchymal Stromal Cells Cultured on PLGA orPLGA/Chitosan Electrospun Nanofibers

Ajalloueian, Fatemeh; Fransson, Moa; Tavanai, Hossein; Massuni, Mohammad et al.

Ingår i Journal of Bioprocessing & Biotechniques, 2015

• DOI för Investigation of Human Mesenchymal Stromal Cells Cultured on PLGA orPLGA/Chitosan Electrospun Nanofibers
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Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Fransson, Moa; Brännström, Johan; Duprez, Ida; Essand, Magnus et al.

Ingår i Regenerative Medicine Research, 2015

• DOI för Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model
• Ladda ner fulltext (pdf) av Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Perfusion Of Porcine Kidneys With Macromolecular Heparin Ameliorates Early Ischemia Reperfusion Injury

Sedigh, Amir; Nordling, Sofia; Larsson, Rolf; Larsson, Erik et al.

Ingår i Transplant International, s. 94-95, 2015

Perturbed endothelial cell Blood interactions during thromboinflammation: Evaluation of a novel treatment for IRI

Nordling, Sofia; Nilsson, Bo; Magnusson, Peetra U.

Ingår i Molecular Immunology, s. 165-166, 2015

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Ingår i Science Signaling, 2015

• DOI för Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Thromboinflammation in Therapeutic Medicine

Nilsson Ekdahl, Kristina; Teramura, Yuji; Asif, Sana; Jonsson, Nina et al.

Ingår i Advances in Experimental Medicine and Biology, s. 3-17, 2015

• DOI för Thromboinflammation in Therapeutic Medicine

Vascular repair utilising immobilised heparin conjugate for protection against early activation of inflammation and coagulation

Nordling, Sofia; Hong, Jaan; Fromell, Karin; Edin, Fredrik et al.

Ingår i Thrombosis and Haemostasis, s. 1312-1322, 2015

• DOI för Vascular repair utilising immobilised heparin conjugate for protection against early activation of inflammation and coagulation

3-D gel culture and time-lapse video microscopy of the human vestibular nerve

Edin, Fredrik; Liu, Wei; Li, Hao; Atturo, Francesca et al.

Ingår i Acta Oto-Laryngologica, s. 1211-1218, 2014

• DOI för 3-D gel culture and time-lapse video microscopy of the human vestibular nerve
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A novel in vitro model for studying the interactions between human whole blood and endothelium

Nordling, Sofia; Nilsson, Bo; Magnusson, Peetra

Ingår i Journal of Visualized Experiments, 2014

• DOI för A novel in vitro model for studying the interactions between human whole blood and endothelium
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Differentiation of human neural progenitor cell-derived spiral ganglion-like neurons: a time-lapse video study

Edin, Fredrik; Liu, Wei; Boström, Marja; Magnusson, Peetra U. et al.

Ingår i Acta Oto-Laryngologica, s. 441-447, 2014

• DOI för Differentiation of human neural progenitor cell-derived spiral ganglion-like neurons: a time-lapse video study
• Ladda ner fulltext (pdf) av Differentiation of human neural progenitor cell-derived spiral ganglion-like neurons: a time-lapse video study

Intranasal Delivery of CNS-Retargeted Human Mesenchymal Stromal Cells Prolongs Treatment Efficacy of Experimental Autoimmune Encephalomyelitis

Fransson, Moa; Piras, Elena; Wang, Hao; Burman, Joachim et al.

Ingår i Immunology, s. 431-441, 2014

• DOI för Intranasal Delivery of CNS-Retargeted Human Mesenchymal Stromal Cells Prolongs Treatment Efficacy of Experimental Autoimmune Encephalomyelitis

Modifying the vessel walls in porcine kidneys during machine perfusion

Sedigh, Amir; Larsson, Rolf; Brännström, Johan; Magnusson, Peetra et al.

Ingår i Journal of Surgical Research, s. 455-462, 2014

• DOI för Modifying the vessel walls in porcine kidneys during machine perfusion

Attachment of macromolecular heparin conjugate to gelatin scaffolds improves endothelial cell infiltration

Leijon, Jonas; Carlsson, Fredrik; Brännström, Johan; Sanchez, Javier et al.

Ingår i Tissue Engineering. Parts A, B and C, s. 1336-1348, 2013

• DOI för Attachment of macromolecular heparin conjugate to gelatin scaffolds improves endothelial cell infiltration
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Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating

Nilsson, Per H.; N. Ekdahl, Kristina; Magnusson, Peetra U.; Qu, Hongchang et al.

Ingår i Biomaterials, s. 985-994, 2013

• DOI för Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating
• Ladda ner fulltext (pdf) av Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating

Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer's Disease

Westman, Gabriel; Lidehall, Anna-Karin; Magnusson, Peetra; Ingelsson, Martin et al.

Ingår i PLOS ONE, 2013

• DOI för Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer's Disease
• Ladda ner fulltext (pdf) av Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer's Disease

Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?

Moll, Guido; Rasmusson-Duprez, Ida; von Bahr, Lena; Connolly-Andersen, Anne-Marie et al.

Ingår i Stem Cells, s. 1565-1574, 2012

• DOI för Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?

Autoregulation of thromboinflammation on biomaterials and cells by a novel therapeutic coating technique

Teramura, Yuji; Nilsson, Per H.; Ekdahl, Kristina N.; Magnusson, Peetra U. et al.

Ingår i Immunobiology, s. 1140-1140, 2012

• DOI för Autoregulation of thromboinflammation on biomaterials and cells by a novel therapeutic coating technique

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

Fransson, Moa; Piras, Elena; Burman, Joachim; Nilsson, Berith et al.

Ingår i Journal of Neuroinflammation, s. 112, 2012

• DOI för CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
• Ladda ner fulltext (pdf) av CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

Oxygen-charged HTK-F6H8 emulsion reduces ischemia: reperfusion injury in kidneys from brain-dead pigs

Asif, Sana; Sedigh, Amir; Nordström, Johan; Brandhorst, Heide et al.

Ingår i Journal of Surgical Research, s. 959-967, 2012

• DOI för Oxygen-charged HTK-F6H8 emulsion reduces ischemia: reperfusion injury in kidneys from brain-dead pigs

Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation

Duprez, Ida Rasmusson; Johansson, Ulrika; Nilsson, Bo; Korsgren, Olle et al.

Ingår i Upsala Journal of Medical Sciences, s. 8-17, 2011

• DOI för Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation

Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis

Cabric, Sanja; Sanchez, Javier; Johansson, Ulrika; Larsson, Rolf et al.

Ingår i Tissue engineering. Part A, s. 961-970, 2010

• DOI för Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis

Mapping pro- and antiangiogenic factors on the surface of prostasomes of normal and malignant cell origin

Babiker, Adil A.; Magnusson, Peetra U.; Ronquist, Gunnar; Nilsson, Bo et al.

Ingår i The Prostate, s. 834-847, 2010

• DOI för Mapping pro- and antiangiogenic factors on the surface of prostasomes of normal and malignant cell origin

Endothelial cell signalling supports pancreatic beta cellfunction in the rat

Johansson, Åsa; Lau, Joey; Sandberg, Monica; Borg, L.A. Håkan et al.

Ingår i Diabetologia, s. 2385-2394, 2009

• DOI för Endothelial cell signalling supports pancreatic beta cellfunction in the rat

Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization

Johansson, Ulrika; Rasmusson, Ida; Niclou, Simone P.; Forslund, Naomi et al.

Ingår i Diabetes, s. 2393-2401, 2008

• DOI för Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization
• Ladda ner fulltext (pdf) av Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Magnusson, Peetra U; Dimberg, Anna; Mellberg, Sofie; Lukinius, Agneta et al.

Ingår i Blood, s. 4214-4222, 2007

• DOI för FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro

Magnusson, Peetra U.; Looman, Camilla; Åhgren, Aive; Wu, Yan et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2142-2149, 2007

• DOI för Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Rolny, Charlotte; Nilsson, Ingrid; Magnusson, Peetra; Armulik, Annika et al.

Ingår i Blood, s. 1877-1886, 2006

• DOI för Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Magnusson, Peetra Ulrica; Ronca, Roberto; Dell'Era, Patrizia; Carlstedt, Pia et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 944-949, 2005

• DOI för Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.

Matsumoto, Taro; Bohman, Svante; Dixelius, Johan; Berge, Tone et al.

Ingår i EMBO J, s. 2342-53, 2005

Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

Magnusson, Peetra; Rolny, Charlotte; Jakobsson, Lars; Wikner, Charlotte et al.

Ingår i Journal of Cell Science, s. 1513-1523, 2004

• DOI för Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Cross, Michael J; Lu, Lingge; Magnusson, Peetra; Nyqvist, Daniel et al.

Ingår i Molecular Biology of the Cell, s. 2881-2893, 2002

• DOI för The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells