Johan Wannberg

Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Akaberi, Dario; Pourghasemi, Monireh; Krambrich, Janina; Berger, Julia et al.

Part of Antimicrobial Agents and Chemotherapy, p. 1-18, 2024

• DOI for Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
• Download full text (pdf) of Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Part of European Journal of Medicinal Chemistry, 2024

• DOI for N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Download full text (pdf) of N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Part of NATURE CANCER, p. 156, 2022

• DOI for Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
• Download full text (pdf) of Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Part of Bioorganic & Medicinal Chemistry, 2021

• DOI for N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Part of ChemistryOpen, p. 114-125, 2019

• DOI for A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
• Download full text (pdf) of A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Akaberi, Dario; Pourghasemi, Monireh; Krambrich, Janina; Berger, Julia et al.

Part of Antimicrobial Agents and Chemotherapy, p. 1-18, 2024

• DOI for Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
• Download full text (pdf) of Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Part of European Journal of Medicinal Chemistry, 2024

• DOI for N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Download full text (pdf) of N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Part of NATURE CANCER, p. 156, 2022

• DOI for Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
• Download full text (pdf) of Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Part of Bioorganic & Medicinal Chemistry, 2021

• DOI for N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Part of ChemistryOpen, p. 114-125, 2019

• DOI for A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
• Download full text (pdf) of A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone

Larsson, Karin; Steinmetz, Julia; Bergqvist, Filip; Arefin, Samsul et al.

Part of British Journal of Pharmacology, p. 4625-4638, 2019

• DOI for Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

Wannberg, Johan; Isaksson, Rebecka; Bremberg, Ulf; Backlund, Maria et al.

Part of Bioorganic & Medicinal Chemistry Letters, p. 519-522, 2018

• DOI for A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions

Kumpina, Ilze; Isaksson, Rebecka; Sävmarker, Jonas; Wannberg, Johan et al.

Part of Organic Process Research & Development, p. 440-445, 2016

• DOI for Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions

Rapid and straightforward transesterification of sulfonyl carbamates

Isaksson, Rebecka; Kumpina, Ilze; Larhed, Mats; Wannberg, Johan

Part of Tetrahedron Letters, p. 1476-1478, 2016

• DOI for Rapid and straightforward transesterification of sulfonyl carbamates

Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401

Wakchaure, Prasad B.; Bremberg, Ulf; Wannberg, Johan; Larhed, Mats

Part of Tetrahedron, p. 6881-6887, 2015

• DOI for Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401

Nonresonant microwave heated continuous flow synthesis in medicinal chemistry

Engen, Karin; Sävmarker, Jonas; Lundback, Thomas; Wannberg, Johan et al.

Part of Abstracts of Papers of the American Chemical Society, 2014

Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Engen, Karin; Sävmarker, Jonas; Rosenström, Ulrika; Wannberg, Johan et al.

Part of Organic Process Research & Development, p. 1582-1588, 2014

• DOI for Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates

Wannberg, Johan; Wallinder, Charlotta; Unlusoy, Meltem; Sköld, Christian et al.

Part of Journal of Organic Chemistry, p. 4184-4189, 2013

• DOI for One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates

HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells

Mahalingam, A. Kannan; Axelsson, Linda; Ekegren, Jenny K.; Wannberg, Johan et al.

Part of Journal of Medicinal Chemistry, p. 607-615, 2010

• DOI for HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells

Stereoselective Synthesis of 3-Aminoindan-1-ones and Subsequent Incorporation into HIV-1 Protease Inhibitors

Arefalk, Anna; Wannberg, Johan; Larhed, Mats; Hallberg, Anders

Part of Journal of Organic Chemistry, p. 1265-1268, 2006

A New Structural Theme in C2-Symmetric HIV-1 Protease Inhibitors: ortho-Substituted P1/P1’ Side Chains

Wannberg, Johan; Sabnis, Yogesh A.; Vrang, Lotta; Samuelsson, Bertil et al.

Part of Bioorganic & Medicinal Chemistry, p. 5303-5315, 2006

Hydroxylamine as an ammonia equivalent in microwave-enhanced aminocarbonylations

Wu, Xiongyu; Wannberg, Johan; Larhed, Mats

Part of Tetrahedron, p. 4665-4670, 2006

Microwave-accelerated synthesis of protease inhibitors

Wannberg, Johan; Ersmark, Karolina; Larhed, Mats

Part of Top. Curr. Chem., p. 3040-3043, 2006

Microwave-Enhanced and Metal-Catalyzed Functionalizations of the 4-Aryl-Dihydropyrimidone Template

Wannberg, Johan; Dallinger, Doris; Kappe, C. Oliver; Larhed, Mats

Part of Journal of combinatorial chemistry, p. 574-583, 2005

High-Speed Synthesis of Potent C2-Symmetric HIV-1 Protease Inhibitors by in Situ Aminocarbonylations

Wannberg, Johan; Kaiser, Nils-Fredrik K.; Vrang, Lotta; Samuelsson, Bertil et al.

Part of Journal of combinatorial chemistry, p. 611-617, 2005

Microwave-enhanced medicinal chemistry: a high-speed opportunity for convenient preparation of protease inhibitors.

Ersmark, Karolina; Larhed, Mats; Wannberg, Johan

Part of Curr Opin Drug Discov Devel, p. 417-27, 2004

Direct microwave synthesis of N,N'-diacylhydrazines and Boc-protected hydrazides by in situ carbonylations under air.

Herrero, Maria Antonia; Wannberg, Johan; Larhed, Mats

Part of Synlett, p. 2335-2338, 2004

Increasing Rates and Scope of Reactions: Sluggish Amines in Microwave-Heated Aminocarbonylation Reactions under Air

Wannberg, Johan; Larhed, Mats

Part of Journal of Organic Chemistry, p. 5750-5753, 2003

• DOI for Increasing Rates and Scope of Reactions: Sluggish Amines in Microwave-Heated Aminocarbonylation Reactions under Air

Controlled microwave heating as an enabling technology: Expedient synthesis of protease inhibitors in perspective

Larhed, Mats; Wannberg, Johan; Hallberg, Anders

Part of QSAR & combinatorial science (Print), p. 51-68, 2007

• DOI for Controlled microwave heating as an enabling technology: Expedient synthesis of protease inhibitors in perspective