Henrik Lodén
Researcher at Department of Pharmaceutical Biosciences; Research; Mass Spectrometry Imaging
- Mobile phone:
- +46 70 408 96 34
- E-mail:
- henrik.loden@uu.se
- Visiting address:
- Husargatan 3
- Postal address:
- Box 591
751 24 UPPSALA
Short presentation
Analytical chemist with many years of experience from academia, private companies and government agency of analysis of drugs and endogenous compounds. Enjoys collaboration as well as running my own projects.
Keywords
- mass spectrometry imaging (msi)
- maldi
- desi
- tissue preparation
- cryosectioning
- statistical evaluation
Biography
PhD in Analytical Pharmaceutical Chemistry from Uppsala University (2008). Have been employed as an analytical chemist for different CRO companies and the Swedish Medical Products Agency before rejoining the group in 2020 (was also a part of the group between 2012-2014).
Research
Main research interest is utilization of MSI for exploratory work, aiming to identify underlying factors behind medical conditions. Also enjoys development projects aiming to increase the versatility of MALDI through derivatization of compounds with low inherent ionization. Internal and external collaboration projects are challenging, but fun!

Publications
Recent publications
Part of Analytical Chemistry, p. 1338-1346, 2025
- DOI for Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
- Download full text (pdf) of Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
Part of Chemical Communications, p. 9238-9241, 2024
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
Part of Scientific Reports, 2018
- DOI for Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
- Download full text (pdf) of Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry
Part of Methods, p. 86-92, 2016
An introduction to MS imaging in drug discovery and development
Part of Bioanalysis, p. 2621-2627, 2015
All publications
Articles in journal
Part of Analytical Chemistry, p. 1338-1346, 2025
- DOI for Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
- Download full text (pdf) of Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues
Part of Chemical Communications, p. 9238-9241, 2024
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
Part of Scientific Reports, 2018
- DOI for Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
- Download full text (pdf) of Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry
Part of Methods, p. 86-92, 2016
An introduction to MS imaging in drug discovery and development
Part of Bioanalysis, p. 2621-2627, 2015
Part of Journal of Chromatography A, p. 181-185, 2008
Principles for different modes of multiple-injection CZE
Part of Electrophoresis, p. 3952-3958, 2008
Quantification of Buserelin in a Pharmaceutical Product by Multiple-injection CZE
Part of Electrophoresis, p. 1548-1556, 2007