Henrik Lodén
Researcher at Department of Pharmaceutical Biosciences; Research; Mass Spectrometry Imaging
- Mobile phone:
- +46 70 408 96 34
- E-mail:
- henrik.loden@uu.se
- Visiting address:
- Husargatan 3
- Postal address:
- Box 591
751 24 UPPSALA
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Short presentation
Analytical chemist with many years of experience from academia, private companies and government agency of analysis of drugs and endogenous compounds. Enjoys collaboration as well as running my own projects.
Keywords
- cryosectioning
- desi
- maldi
- mass spectrometry imaging (msi)
- statistical evaluation
- tissue preparation
Biography
PhD in Analytical Pharmaceutical Chemistry from Uppsala University (2008). Have been employed as an analytical chemist for different CRO companies and the Swedish Medical Products Agency before rejoining the group in 2020 (was also a part of the group between 2012-2014).
Research
Main research interest is utilization of MSI for exploratory work, aiming to identify underlying factors behind medical conditions. Also enjoys development projects aiming to increase the versatility of MALDI through derivatization of compounds with low inherent ionization. Internal and external collaboration projects are challenging, but fun!
Publications
Recent publications
- Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging (2024)
- Peptide ion channel toxins from the bootlace worm, the longest animal on Earth (2018)
- Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry (2016)
- An introduction to MS imaging in drug discovery and development (2015)
- Principles for different modes of multiple-injection CZE (2008)
All publications
Articles
- Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging (2024)
- Peptide ion channel toxins from the bootlace worm, the longest animal on Earth (2018)
- Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry (2016)
- An introduction to MS imaging in drug discovery and development (2015)
- Principles for different modes of multiple-injection CZE (2008)
- Quantitative determination of salbutamol in tablets by multiple-injection capillary zone electrophoresis (2008)
- Quantification of Buserelin in a Pharmaceutical Product by Multiple-injection CZE (2007)