Fabio Rabelo Melo

Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Part of Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI for Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
• Download full text (pdf) of Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells

Zhao, Xinran O.; Melo, Fabio Rabelo; Sommerhoff, Christian P.; Paivandy, Aida et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024

• DOI for Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
• Download full text (pdf) of Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells

Monensin induces secretory granule-mediated cell death in eosinophils

Vraila, Marianthi; Asp, Elin; Melo, Fabio R.; Grujic, Mirjana et al.

Part of Journal of Allergy and Clinical Immunology, 2023

• DOI for Monensin induces secretory granule-mediated cell death in eosinophils
• Download full text (pdf) of Monensin induces secretory granule-mediated cell death in eosinophils

Mast cell tryptase potentiates neutrophil extracellular trap formation

Pejler, Gunnar; Alanazi, Sultan; Grujic, Mirjana; Adler, Jeremy et al.

Part of Journal of Innate Immunity, p. 433-446, 2022

• DOI for Mast cell tryptase potentiates neutrophil extracellular trap formation
• Download full text (pdf) of Mast cell tryptase potentiates neutrophil extracellular trap formation

Mast cell chymase has a negative impact on human osteoblasts

Lind, Thomas; Melo, Fabio R.; Gustafson, Ann-Marie; Sundqvist, Anders et al.

Part of Matrix Biology, p. 1-19, 2022

• DOI for Mast cell chymase has a negative impact on human osteoblasts
• Download full text (pdf) of Mast cell chymase has a negative impact on human osteoblasts

Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Part of Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI for Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
• Download full text (pdf) of Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells

Zhao, Xinran O.; Melo, Fabio Rabelo; Sommerhoff, Christian P.; Paivandy, Aida et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024

• DOI for Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
• Download full text (pdf) of Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells

Monensin induces secretory granule-mediated cell death in eosinophils

Vraila, Marianthi; Asp, Elin; Melo, Fabio R.; Grujic, Mirjana et al.

Part of Journal of Allergy and Clinical Immunology, 2023

• DOI for Monensin induces secretory granule-mediated cell death in eosinophils
• Download full text (pdf) of Monensin induces secretory granule-mediated cell death in eosinophils

Mast cell tryptase potentiates neutrophil extracellular trap formation

Pejler, Gunnar; Alanazi, Sultan; Grujic, Mirjana; Adler, Jeremy et al.

Part of Journal of Innate Immunity, p. 433-446, 2022

• DOI for Mast cell tryptase potentiates neutrophil extracellular trap formation
• Download full text (pdf) of Mast cell tryptase potentiates neutrophil extracellular trap formation

Mast cell chymase has a negative impact on human osteoblasts

Lind, Thomas; Melo, Fabio R.; Gustafson, Ann-Marie; Sundqvist, Anders et al.

Part of Matrix Biology, p. 1-19, 2022

• DOI for Mast cell chymase has a negative impact on human osteoblasts
• Download full text (pdf) of Mast cell chymase has a negative impact on human osteoblasts

Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells

Alanazi, Sultan; Melo, Fabio Rabelo; Pejler, Gunnar

Part of Frontiers in Immunology, 2021

• DOI for Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells
• Download full text (pdf) of Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells

Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells

von Beek, Christopher; Alriksson, Linnéa; Palle, Josefine; Gustafson, Ann-Marie et al.

Part of PLOS ONE, 2021

• DOI for Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells
• Download full text (pdf) of Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells

Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Alanazi, Sultan; Grujic, Mirjana; Lampinen, Maria; Rollman, Ola et al.

Part of International Journal of Molecular Sciences, 2020

• DOI for Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA
• Download full text (pdf) of Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis

Alanazi, Sultan; Melo, Fabio R.; Pejler, Gunnar

Part of Anticancer Research, p. 2525-2536, 2020

• DOI for Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis

Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism

von Beek, Christopher; Waern, Ida; Eriksson, Jens; Melo, Fabio R. et al.

Part of Cellular Microbiology, 2019

• DOI for Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
• Download full text (pdf) of Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism

Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

Melo, Fabio R.; Martin, Sebastin Santosh; Sommerhoff, Christian P.; Pejler, Gunnar

Part of Cell Death and Disease, 2019

• DOI for Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression
• Download full text (pdf) of Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells

Martin, Sebastin Santosh; Melo, Fabio R.; Pejler, Gunnar

Part of Cells, 2019

• DOI for The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells
• Download full text (pdf) of The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells

Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production

Paivandy, Aida; Eriksson, Jens; Melo, Fabio R.; Sellin, Mikael E. et al.

Part of Cell Death Discovery, 2019

• DOI for Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
• Download full text (pdf) of Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production

Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules

Frisk, Jun Mei Hu; Kjellén, Lena; Melo, Fabio R.; Öhrvik, Helena et al.

Part of Frontiers in Immunology, 2018

• DOI for Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules
• Download full text (pdf) of Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules

Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

Paivandy, Aida; Sandelin, Martin; Igelström, Helena; Landelius, Per et al.

Part of Frontiers in Immunology, 2017

• DOI for Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells
• Download full text (pdf) of Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells

Melo, Fabio R.; Wallerman, Ola; Paivandy, Aida; Calounova, Gabriela et al.

Part of Journal of Allergy and Clinical Immunology, p. 474-485, 2017

• DOI for Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells

Induction of mast cell apoptosis by a novel secretory granule-mediated pathway.

Melo, Fabio R; Wernersson, Sara; Pejler, Gunnar

Part of Methods in Molecular Biology, p. 325-37, 2015

• DOI for Induction of mast cell apoptosis by a novel secretory granule-mediated pathway.