Fabio Rabelo Melo

The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration

Punga, Tanel; Larsson, Mårten; Mujica, Endrina; Melo, Fabio R. et al.

Part of Scientific Reports, 2026

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Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for Asthma

Pejler, Gunnar; Paivandy, Aida; Melo, Fabio R.; Allam, Venkata et al.

Part of Inflammation, 2026

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Melanoma cells suppress mast cell function via a melanin-dependent mechanism

Melo, Fabio R.; Nyman, Lea; Österman Menander, Ida; Grujic, Mirjana et al.

Part of The FEBS Journal, p. 6075-6099, 2025

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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Part of Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI for Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells

Zhao, Xinran O.; Melo, Fabio Rabelo; Sommerhoff, Christian P.; Paivandy, Aida et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024

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The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration

Punga, Tanel; Larsson, Mårten; Mujica, Endrina; Melo, Fabio R. et al.

Part of Scientific Reports, 2026

• DOI for The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration
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Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for Asthma

Pejler, Gunnar; Paivandy, Aida; Melo, Fabio R.; Allam, Venkata et al.

Part of Inflammation, 2026

• DOI for Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for Asthma
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Melanoma cells suppress mast cell function via a melanin-dependent mechanism

Melo, Fabio R.; Nyman, Lea; Österman Menander, Ida; Grujic, Mirjana et al.

Part of The FEBS Journal, p. 6075-6099, 2025

• DOI for Melanoma cells suppress mast cell function via a melanin-dependent mechanism
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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Part of Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI for Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells

Zhao, Xinran O.; Melo, Fabio Rabelo; Sommerhoff, Christian P.; Paivandy, Aida et al.

Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024

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Monensin induces secretory granule-mediated cell death in eosinophils

Vraila, Marianthi; Asp, Elin; Melo, Fabio R.; Grujic, Mirjana et al.

Part of Journal of Allergy and Clinical Immunology, 2023

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Mast cell tryptase potentiates neutrophil extracellular trap formation

Pejler, Gunnar; Alanazi, Sultan; Grujic, Mirjana; Adler, Jeremy et al.

Part of Journal of Innate Immunity, p. 433-446, 2022

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Mast cell chymase has a negative impact on human osteoblasts

Lind, Thomas; Melo, Fabio R.; Gustafson, Ann-Marie; Sundqvist, Anders et al.

Part of Matrix Biology, p. 1-19, 2022

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Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells

Alanazi, Sultan; Melo, Fabio Rabelo; Pejler, Gunnar

Part of Frontiers in Immunology, 2021

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Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells

von Beek, Christopher; Alriksson, Linnéa; Palle, Josefine; Gustafson, Ann-Marie et al.

Part of PLOS ONE, 2021

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Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Alanazi, Sultan; Grujic, Mirjana; Lampinen, Maria; Rollman, Ola et al.

Part of International Journal of Molecular Sciences, 2020

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Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis

Alanazi, Sultan; Melo, Fabio R.; Pejler, Gunnar

Part of Anticancer Research, p. 2525-2536, 2020

• DOI for Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis

Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism

von Beek, Christopher; Waern, Ida; Eriksson, Jens; Melo, Fabio R. et al.

Part of Cellular Microbiology, 2019

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Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

Melo, Fabio R.; Martin, Sebastin Santosh; Sommerhoff, Christian P.; Pejler, Gunnar

Part of Cell Death and Disease, 2019

• DOI for Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression
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The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells

Martin, Sebastin Santosh; Melo, Fabio R.; Pejler, Gunnar

Part of Cells, 2019

• DOI for The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells
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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production

Paivandy, Aida; Eriksson, Jens; Melo, Fabio R.; Sellin, Mikael E. et al.

Part of Cell Death Discovery, 2019

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Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules

Frisk, Jun Mei Hu; Kjellén, Lena; Melo, Fabio R.; Öhrvik, Helena et al.

Part of Frontiers in Immunology, 2018

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Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

Paivandy, Aida; Sandelin, Martin; Igelström, Helena; Landelius, Per et al.

Part of Frontiers in Immunology, 2017

• DOI for Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells
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Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells

Melo, Fabio R.; Wallerman, Ola; Paivandy, Aida; Calounova, Gabriela et al.

Part of Journal of Allergy and Clinical Immunology, p. 474-485, 2017

• DOI for Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells

Induction of mast cell apoptosis by a novel secretory granule-mediated pathway.

Melo, Fabio R; Wernersson, Sara; Pejler, Gunnar

Part of Methods in Molecular Biology, p. 325-37, 2015

• DOI for Induction of mast cell apoptosis by a novel secretory granule-mediated pathway.