Maria João Pereira

Role of FKBP5 in adipose tissue function: Implications for obesity and insulin sensitivity

Laterveer, Rutger; Hetty, Susanne; Mathioudaki, Argyri; Lundqvist, Martin H. et al.

Part of Molecular and Cellular Endocrinology, 2026

• DOI for Role of FKBP5 in adipose tissue function: Implications for obesity and insulin sensitivity
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Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes

Ahmed, Fozia; Hetty, Susanne; Laterveer, Rutger; Surucu, Ece Busra et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2025

• DOI for Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes
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Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet

Fanni, Giovanni; Hukema, Fleur W.; Hetty, Susanne; Mathioudaki, Argyri et al.

Part of Diabetes, obesity and metabolism, p. 4836-4846, 2025

• DOI for Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet
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Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet

Fanni, Giovanni; Hukema, Fleur W.; Hetty, Susanne; Mathioudaki, Argyri et al.

Part of Diabetes, obesity and metabolism, p. 4836-4846, 2025

• DOI for Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet
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Depot-specific metabolic and inflammatory profiles in perirenal and renal sinus adipose tissue

Pereira, Maria J.; Mathioudaki, Argyri; Hetty, Susanne; Sedigh, Amir et al.

Part of Molecular Medicine, 2025

• DOI for Depot-specific metabolic and inflammatory profiles in perirenal and renal sinus adipose tissue
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Role of FKBP5 in adipose tissue function: Implications for obesity and insulin sensitivity

Laterveer, Rutger; Hetty, Susanne; Mathioudaki, Argyri; Lundqvist, Martin H. et al.

Part of Molecular and Cellular Endocrinology, 2026

• DOI for Role of FKBP5 in adipose tissue function: Implications for obesity and insulin sensitivity
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Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes

Ahmed, Fozia; Hetty, Susanne; Laterveer, Rutger; Surucu, Ece Busra et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2025

• DOI for Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes
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Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet

Fanni, Giovanni; Hukema, Fleur W.; Hetty, Susanne; Mathioudaki, Argyri et al.

Part of Diabetes, obesity and metabolism, p. 4836-4846, 2025

• DOI for Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet
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Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet

Fanni, Giovanni; Hukema, Fleur W.; Hetty, Susanne; Mathioudaki, Argyri et al.

Part of Diabetes, obesity and metabolism, p. 4836-4846, 2025

• DOI for Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet
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Depot-specific metabolic and inflammatory profiles in perirenal and renal sinus adipose tissue

Pereira, Maria J.; Mathioudaki, Argyri; Hetty, Susanne; Sedigh, Amir et al.

Part of Molecular Medicine, 2025

• DOI for Depot-specific metabolic and inflammatory profiles in perirenal and renal sinus adipose tissue
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Abundance of dopamine and its receptors in the brain and adipose tissue following diet-induced obesity or caloric restriction

Hukema, Fleur W.; Hetty, Susanne; Kagios, Christakis; Zelleroth, Sofia et al.

Part of Translational Research, p. 41-54, 2025

• DOI for Abundance of dopamine and its receptors in the brain and adipose tissue following diet-induced obesity or caloric restriction
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Cafeteria diet and caloric restriction affect metabolic but not behavioral characteristics in male Wistar rats

Kagios, Christakis; Hetty, Susanne; Grönbladh, Alfhild; Pereira, Maria J. et al.

Part of Physiology and Behavior, 2025

• DOI for Cafeteria diet and caloric restriction affect metabolic but not behavioral characteristics in male Wistar rats
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High percentage of immune Th1 and Tc1 cells infiltrating visceral adipose tissue in people with obesity

Barbosa, Pedro; Pinho, Aryane; Lazaro, Andre; Paula, Diogo et al.

Part of Obesity Research and Clinical Practice, p. 426-435, 2024

• DOI for High percentage of immune Th1 and Tc1 cells infiltrating visceral adipose tissue in people with obesity

Metabolomic Profiling of Adipose Tissue in Type 2 Diabetes: Associations with Obesity and Insulin Resistance

Mathioudaki, Argyri; Fanni, Giovanni; Eriksson, Jan W.; Pereira, Maria J.

Part of Metabolites, 2024

• DOI for Metabolomic Profiling of Adipose Tissue in Type 2 Diabetes: Associations with Obesity and Insulin Resistance
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Similar early metabolic changes induced by dietary weight loss or bariatric surgery. Reply to Taylor R [letter].

Eriksson, Jan W; Pereira, Maria J.; Fanni, Giovanni; Risérus, Ulf et al.

Part of Diabetologia, p. 2605-2607, 2024

• DOI for Similar early metabolic changes induced by dietary weight loss or bariatric surgery. Reply to Taylor R [letter].

Autonomic nervous system responses to hypo- and hyperglycemia in type 2 diabetes and prediabetes

Lundqvist, Martin H.; Pereira, Maria J.; Wiklund, Urban; Hetty, Susanne et al.

Part of European Journal of Endocrinology, p. 499-508, 2024

• DOI for Autonomic nervous system responses to hypo- and hyperglycemia in type 2 diabetes and prediabetes
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Short-term effects of obesity surgery versus low-energy diet on body composition and tissue-specific glucose uptake: a randomised clinical study using whole-body integrated ¹⁸F-FDG-PET/MRI

Eriksson, Jan; Pereira, Maria J.; Kagios, Christakis; Kvernby, Sofia et al.

Part of Diabetologia, p. 1399-1412, 2024

• DOI for Short-term effects of obesity surgery versus low-energy diet on body composition and tissue-specific glucose uptake: a randomised clinical study using whole-body integrated ¹⁸F-FDG-PET/MRI
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Renal sinus adipose tissue: exploratory study of metabolic features and transcriptome compared with omental and subcutaneous adipose tissue

Pereira, Maria J.; Mathioudaki, Argyri; Otero, Alicia G.; Duvvuri, Padma Priya et al.

Part of Obesity, p. 1870-1884, 2024

• DOI for Renal sinus adipose tissue: exploratory study of metabolic features and transcriptome compared with omental and subcutaneous adipose tissue
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The role of CD20⁺ T cells: Insights in human peripheral blood

Pinho, Aryane Cruz Oliveira; Barbosa, Pedro; Pereira, Maria J.; Paiva, Artur et al.

Part of Cytometry. Part B, Clinical cytometry., p. 171-180, 2024

• DOI for The role of CD20⁺ T cells: Insights in human peripheral blood
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Identification and characterization of circulating and adipose tissue infiltrated CD20⁺ T cells from subjects with obesity that undergo bariatric surgery

Cruz Oliveira Pinho, Aryane; Barbosa, Pedro; Lazaro, André; Tralhão, José G. et al.

Part of Immunology Letters, 2024

• DOI for Identification and characterization of circulating and adipose tissue infiltrated CD20⁺ T cells from subjects with obesity that undergo bariatric surgery
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Regulation of the Cortisol Axis, Glucagon, and Growth Hormone by Glucose Is Altered in Prediabetes and Type 2 Diabetes

Lundqvist, Martin H.; Pereira, Maria J.; Almby, Kristina E.; Hetty, Susanne et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2024

• DOI for Regulation of the Cortisol Axis, Glucagon, and Growth Hormone by Glucose Is Altered in Prediabetes and Type 2 Diabetes
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Subcutaneous adipose tissue dopamine D2 receptor expression is increased in prediabetes and T2D

Vranic, Milica; Ahmed, Fozia; Kristófi, Robin; Hetty, Susanne et al.

Part of Endocrine, 2024

• DOI for Subcutaneous adipose tissue dopamine D2 receptor expression is increased in prediabetes and T2D
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Bariatric Surgery Induces Alterations in the Immune Profile of Peripheral Blood T Cells

Barbosa, Pedro; Pinho, Aryane; Lazaro, Andre; Paula, Diogo et al.

Part of Biomolecules, 2024

• DOI for Bariatric Surgery Induces Alterations in the Immune Profile of Peripheral Blood T Cells
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CD248 promotes insulin resistance by binding to the insulin receptor and dampening its insulin-induced autophosphorylation

Benedet, Patricia O.; Safikhan, Nooshin S.; Pereira, Maria J.; Lum, Bryan M. et al.

Part of EBioMedicine, 2024

• DOI for CD248 promotes insulin resistance by binding to the insulin receptor and dampening its insulin-induced autophosphorylation
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CD8+Treg cells play a role in the obesity-associated insulin resistance

Barbosa, Pedro; Pinho, Aryane; Lazaro, Andre; Rosendo-Silva, Daniela et al.

Part of Life Sciences, 2024

• DOI for CD8+Treg cells play a role in the obesity-associated insulin resistance
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CABLES1 expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism

Hetty, Susanne; Vranic, Milica; Kamble, Prasad G.; Lundqvist, Martin H. et al.

Part of Adipocyte, 2023

• DOI for CABLES1 expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism
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Several Metabolite Families Display Inflexibility during Glucose Challenge in Patients with Type 2 Diabetes: An Untargeted Metabolomics Study

Fanni, Giovanni; Eriksson, Jan; Pereira, Maria J.

Part of Metabolites, 2023

• DOI for Several Metabolite Families Display Inflexibility during Glucose Challenge in Patients with Type 2 Diabetes: An Untargeted Metabolomics Study
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Increased OCT3 Expression in Adipose Tissue With Aging: Implications for Catecholamine and Lipid Turnover and Insulin Resistance in Women

Ahmed, Fozia; Vranic, Milica; Hetty, Susanne; Mathioudaki, Argyri et al.

Part of Endocrinology, 2023

• DOI for Increased OCT3 Expression in Adipose Tissue With Aging: Implications for Catecholamine and Lipid Turnover and Insulin Resistance in Women
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Glucose-dependent inflammatory responses in obese compared to lean individuals

Lundqvist, Martin H.; Pereira, Maria J.; Eriksson, Jan

Part of Endocrine, p. 464-476, 2023

• DOI for Glucose-dependent inflammatory responses in obese compared to lean individuals
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Positional and compositional analysis of saturated, monounsaturated, and polyunsaturated fatty acids in human adipose tissue triglyceride by ¹³ C nuclear magnetic resonance

Torres, Alejandra N; Tavares, Ludgero; Pereira, Maria J.; Eriksson, Jan et al.

Part of NMR in Biomedicine, 2023

• DOI for Positional and compositional analysis of saturated, monounsaturated, and polyunsaturated fatty acids in human adipose tissue triglyceride by ¹³ C nuclear magnetic resonance

Interleukin-33 inhibits glucose uptake in human adipocytes and its expression in adipose tissue is elevated in insulin resistance and type 2 diabetes

Pereira, Maria J.; Azim, Ayesha; Hetty, Susanne; Jui Nandi, Bipasha et al.

Part of Cytokine, 2023

• DOI for Interleukin-33 inhibits glucose uptake in human adipocytes and its expression in adipose tissue is elevated in insulin resistance and type 2 diabetes
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Effects of the second-generation antipsychotic drugs aripiprazole and olanzapine on human adipocyte differentiation

Vranic, Milica; Ahmed, Fozia; Hetty, Susanne; Sarsenbayeva, Assel et al.

Part of Molecular and Cellular Endocrinology, 2023

• DOI for Effects of the second-generation antipsychotic drugs aripiprazole and olanzapine on human adipocyte differentiation
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Evaluation of RNA Isolation Methods in Human Adipose Tissue

Jui, Bipasha Nandi; Sarsenbayeva, Assel; Jernow, Henning; Hetty, Susanne et al.

Part of Laboratory medicine, 2022

• DOI for Evaluation of RNA Isolation Methods in Human Adipose Tissue

Role of Estrogen and Its Receptors in Adipose Tissue Glucose Metabolism in Pre- and Postmenopausal Women

Ahmed, Fozia; Kamble, Prasad G.; Hetty, Susanne; Fanni, Giovanni et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2022

• DOI for Role of Estrogen and Its Receptors in Adipose Tissue Glucose Metabolism in Pre- and Postmenopausal Women
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Response of multiple hormones to glucose and arginine challenge in T2DM after gastric bypass

Fanni, Giovanni; Katsogiannos, Petros; Jui Nandi, Bipasha; Sundbom, Magnus et al.

Part of Endocrine Connections, 2022

• DOI for Response of multiple hormones to glucose and arginine challenge in T2DM after gastric bypass
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ESR2 expression in subcutaneous adipose tissue is related to body fat distribution in women, and knockdown impairs preadipocyte differentiation

Ahmed, Fozia; Hetty, Susanne; Vranic, Milica; Fanni, Giovanni et al.

Part of Adipocyte, p. 434-447, 2022

• DOI for ESR2 expression in subcutaneous adipose tissue is related to body fat distribution in women, and knockdown impairs preadipocyte differentiation
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Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight

Ferreira, Vitor; Folgueira, Cintia; Guillen, Maria; Zubiaur, Pablo et al.

Part of Metabolism, 2022

• DOI for Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight
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Human adipose tissue gene expression of solute carrier family 19 member 3 ( SLC19A3 ): relation to obesity and weight‐loss

Pereira, Maria J.; Andersson‐Assarsson, Johanna C; Jacobson, Peter; Kamble, Prasad G. et al.

Part of Obesity Science & Practice, p. 21-31, 2022

• DOI for Human adipose tissue gene expression of solute carrier family 19 member 3 ( SLC19A3 ): relation to obesity and weight‐loss
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CDKN2C expression in adipose tissue is reduced in type II diabetes and central obesity: impact on adipocyte differentiation and lipid storage?

Pereira, Maria J.; Vranic, Milica; Kamble, Prasad G.; Jernow, Henning et al.

Part of Translational Research, p. 105-121, 2022

• DOI for CDKN2C expression in adipose tissue is reduced in type II diabetes and central obesity: impact on adipocyte differentiation and lipid storage?
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Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Part of Cell Reports Medicine, 2022

• DOI for Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
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Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells

Sarsenbayeva, Assel; Pereira, Maria J.; Jui Nandi, Bipasha; Ahmed, Fozia et al.

Part of Biochemical Pharmacology, 2022

• DOI for Excess glucocorticoid exposure contributes to adipose tissue fibrosis which involves macrophage interaction with adipose precursor cells
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Macrophage-derived secretome is sufficient to confer olanzapine-mediated insulin resistance in human adipocytes

Dipta, Priya; Sarsenbayeva, Assel; Shmuel, Miriam; Forno, Francesca et al.

Part of Comprehensive Psychoneuroendocrinology, 2021

• DOI for Macrophage-derived secretome is sufficient to confer olanzapine-mediated insulin resistance in human adipocytes
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Impaired HMG-CoA reductase activity caused by genetic variants or statin exposure: impact on human adipose tissue, β-cells and metabolome

Sarsenbayeva, Assel; Jui Nandi, Bipasha; Fanni, Giovanni; Barbosa, Pedro et al.

Part of Metabolites, 2021

• DOI for Impaired HMG-CoA reductase activity caused by genetic variants or statin exposure: impact on human adipose tissue, β-cells and metabolome
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Human macrophages stimulate expression of inflammatory mediators in adipocytes; effects of second-generation antipsychotics and glucocorticoids on cellular cross-talk

Sarsenbayeva, Assel; Dipta, Priya; Lundqvist, Martin H.; Almby, Kristina E. et al.

Part of Psychoneuroendocrinology, 2021

• DOI for Human macrophages stimulate expression of inflammatory mediators in adipocytes; effects of second-generation antipsychotics and glucocorticoids on cellular cross-talk
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Tissue-specific glucose partitioning and fat content in prediabetes and type 2 diabetes: whole-body PET/MRI during hyperinsulinemia

Eriksson, Jan W; Visvanathar, Robin; Kullberg, Joel; Strand, Robin et al.

Part of European Journal of Endocrinology, p. 879-889, 2021

• DOI for Tissue-specific glucose partitioning and fat content in prediabetes and type 2 diabetes: whole-body PET/MRI during hyperinsulinemia

Altered hormonal and autonomic nerve responses to hypo- and hyperglycaemia are found in overweight and insulin-resistant individuals and may contribute to the development of type 2 diabetes.

Lundqvist, Martin H.; Almby, Kristina E.; Wiklund, Urban; Abrahamsson, Niclas et al.

Part of Diabetologia, p. 641-655, 2021

• DOI for Altered hormonal and autonomic nerve responses to hypo- and hyperglycaemia are found in overweight and insulin-resistant individuals and may contribute to the development of type 2 diabetes.

Time Course of Metabolic, Neuroendocrine, and Adipose Effects During 2 Years of Follow-up After Gastric Bypass in Patients With Type 2 Diabetes

Almby, Kristina E.; Katsogiannos, Petros; Pereira, Maria J.; Karlsson, Anders et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2021

• DOI for Time Course of Metabolic, Neuroendocrine, and Adipose Effects During 2 Years of Follow-up After Gastric Bypass in Patients With Type 2 Diabetes
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Effects of Gastric Bypass Surgery on the Brain: Simultaneous Assessment of Glucose Uptake, Blood Flow, Neural Activity, and Cognitive Function During Normo- and Hypoglycemia

Almby, Kristina E.; Lundqvist, Martin H.; Abrahamsson, Niclas; Kvernby, Sofia et al.

Part of Diabetes, p. 1265-1277, 2021

• DOI for Effects of Gastric Bypass Surgery on the Brain: Simultaneous Assessment of Glucose Uptake, Blood Flow, Neural Activity, and Cognitive Function During Normo- and Hypoglycemia

Changes in Circulating Cytokines and Adipokines After RYGB in Patients with and without Type 2 Diabetes

Katsogiannos, Petros; Kamble, Prasad G.; Pereira, Maria J.; Sundbom, Magnus et al.

Part of Obesity, p. 535-542, 2021

• DOI for Changes in Circulating Cytokines and Adipokines After RYGB in Patients with and without Type 2 Diabetes
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Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes

Diamanti, Klev; Visvanathar, Robin; Pereira, Maria J.; Cavalli, Marco et al.

Part of Scientific Reports, 2020

• DOI for Integration of whole-body [¹⁸F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes
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Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery

Katsogiannos, Petros; Kamble, Prasad G.; Wiklund, Urban; Sundbom, Magnus et al.

Part of Endocrine, p. 344-353, 2020

• DOI for Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery
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Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism

Kamble, Prasad G.; Hetty, Susanne; Vranic, Milica; Almby, Kristina et al.

Part of Scientific Reports, 2020

• DOI for Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism
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Validation of automated whole-body analysis of metabolic and morphological parameters from an integrated FDG-PET/MRI acquisition

Guglielmo, Priscilla; Ekström, Simon; Strand, Robin; Visvanathar, Robin et al.

Part of Scientific Reports, 2020

• DOI for Validation of automated whole-body analysis of metabolic and morphological parameters from an integrated FDG-PET/MRI acquisition
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The effects of bisphenol A and bisphenol S on adipokine expression and glucose metabolism in human adipose tissue

Ahmed, Fozia; Sarsenbayeva, Assel; Katsogiannos, Petros; Aguer, Céline et al.

Part of Toxicology, 2020

• DOI for The effects of bisphenol A and bisphenol S on adipokine expression and glucose metabolism in human adipose tissue
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Type B insulin resistance syndrome in a patient with type 1 diabetes

Sjoholm, Ake; Pereira, Maria João; Nilsson, Thomas; Linde, Torbjörn et al.

Part of Endocrinology, diabetes & metabolism case reports, 2020

• DOI for Type B insulin resistance syndrome in a patient with type 1 diabetes
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Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes

Pereira, Maria J; Thombare, Ketan; Sarsenbayeva, Assel; Kamble, Prasad G. et al.

Part of Molecular and Cellular Endocrinology, 2020

• DOI for Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes

Early Changes in Adipose Tissue Morphology, Gene Expression, and Metabolism After RYGB in Patients With Obesity and T2D

Katsogiannos, Petros; Kamble, Prasad G.; Boersma, Greta J.; Karlsson, F. Anders et al.

Part of Journal of Clinical Endocrinology and Metabolism, p. 2601-2613, 2019

• DOI for Early Changes in Adipose Tissue Morphology, Gene Expression, and Metabolism After RYGB in Patients With Obesity and T2D

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Diamanti, Klev; Cavalli, Marco; Pan, Gang; Pereira, Maria J et al.

Part of Scientific Reports, 2019

• DOI for Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes
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Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism

Sarsenbayeva, Assel; Marques-Santos, Cátia M.; Thombare, Ketan; Di Nunzio, Giada et al.

Part of Psychoneuroendocrinology, 2019

• DOI for Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism
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Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor alpha and beta in insulin resistance?

Kamble, Prasad G.; Pereira, Maria J; Almby, Kristina E.; Eriksson, Jan

Part of Molecular and Cellular Endocrinology, p. 28-36, 2019

• DOI for Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor alpha and beta in insulin resistance?

Glucagon Levels During Short-Term SGLT2 Inhibition Are Largely Regulated by Glucose Changes in Patients With Type 2 Diabetes.

Lundkvist, Per; Pereira, Maria J.; Kamble, Prasad G.; Katsogiannos, Petros et al.

Part of Journal of Clinical Endocrinology and Metabolism, p. 193-201, 2019

• DOI for Glucagon Levels During Short-Term SGLT2 Inhibition Are Largely Regulated by Glucose Changes in Patients With Type 2 Diabetes.

Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity

Pereira, Maria J; Eriksson, Jan

Part of Drugs, p. 219-230, 2019

• DOI for Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity
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Calcineurin is an important factor involved in glucose uptake in human adipocytes

Fonseca, Ana Catarina R. G.; Carvalho, Eugenia; Eriksson, Jan; Pereira, Maria J

Part of Molecular and Cellular Biochemistry, p. 157-168, 2018

• DOI for Calcineurin is an important factor involved in glucose uptake in human adipocytes
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FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes

Sidibeh, Cherno O; Pereira, Maria J; Abalo, Xesus; Boersma, Gretha J. et al.

Part of Endocrine, p. 116-128, 2018

• DOI for FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes
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Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction

Hansson, Sara F.; Zhou, Alex-Xianghua; Vachet, Pauline; Eriksson, Jan W et al.

Part of PLOS ONE, 2018

• DOI for Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction
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Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.

Kamble, Prasad G.; Pereira, Maria J; Gustafsson, Stefan; Lundkvist, Per et al.

Part of Adipocyte, p. 285-296, 2018

• DOI for Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.
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Direct effects of glucagon on human adipose tissue metabolism

Pereira, Maria J; Boersma, Greta J.; Kamble, Prasad G.; Lundkvist, Per et al.

Part of Diabetologia, 2018

FKBP51 ablation using CRISPR/Cas-9 impairs adipocyte differentiation

Castillejo-Lopez, Casimiro; Abalo, Xesus M.; Sidibeh, Cherno O; Pereira, Maria J et al.

Part of Diabetologia, 2018

Estrogen and glucocorticoid effects on lipocalin 2 expression in human adipose tissue: A role of ER beta pathway in insulin resistance?

Kamble, Prasad G.; Pereira, Maria J; Boersma, Greta J.; Almby, Kristina E. et al.

Part of Diabetologia, 2018

Altered Glucose Uptake in Muscle, Visceral Adipose Tissue, and Brain Predict Whole-Body Insulin Resistance and may Contribute to the Development of Type 2 Diabetes: A Combined PET/MR Study

Boersma, Greta J.; Johansson, Emil; Pereira, Maria J; Heurling, Kerstin et al.

Part of Hormone and Metabolic Research, p. 627-639, 2018

• DOI for Altered Glucose Uptake in Muscle, Visceral Adipose Tissue, and Brain Predict Whole-Body Insulin Resistance and may Contribute to the Development of Type 2 Diabetes: A Combined PET/MR Study

A Randomized Controlled Trial of Dapagliflozin Plus Once-Weekly Exenatide Versus Placebo in Individuals with Obesity and Without Diabetes: Metabolic Effects and Markers Associated with Bodyweight Loss

Pereira, Maria J; Lundkvist, Per; Kamble, Prasad G.; Lau, Joey et al.

Part of Diabetes Therapy, p. 1511-1532, 2018

• DOI for A Randomized Controlled Trial of Dapagliflozin Plus Once-Weekly Exenatide Versus Placebo in Individuals with Obesity and Without Diabetes: Metabolic Effects and Markers Associated with Bodyweight Loss
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Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers

Kamble, Prasad G.; Gustafsson, Stefan; Pereira, Maria J; Lundkvist, Per et al.

Part of Upsala Journal of Medical Sciences, p. 234-242, 2017

• DOI for Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers
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Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance

Sidibeh, Cherno O.; Pereira, Maria J.; Börjesson, Joey Lau; Kamble, Prasad G. et al.

Part of Endocrine, p. 839-852, 2017

• DOI for Role of cannabinoid receptor 1 in human adipose tissue for lipolysis regulation and insulin resistance
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Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: Sustained reductions in body weight, glycaemia and blood pressure over 1 year

Lundkvist, Per; Pereira, Maria J; Katsogiannos, Petros; Sjöström, C. David et al.

Part of Diabetes, obesity and metabolism, p. 1276-1288, 2017

• DOI for Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: Sustained reductions in body weight, glycaemia and blood pressure over 1 year
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Dapagliflozin once-daily and exenatide once-weekly dual therapy: A 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes

Lundkvist, Per; Sjöström, C. David; Amini, Sam; Pereira, Maria J. et al.

Part of Diabetes, obesity and metabolism, p. 49-60, 2017

• DOI for Dapagliflozin once-daily and exenatide once-weekly dual therapy: A 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes
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PPARG Pro12Ala variant in relation to adipose tissue metabolism and differentiation: a small genotype-based recall study

Kamble, Prasad G.; Pereira, Maria J; Gustafsson, Stefan; Lundkvist, Per et al.

Part of Diabetologia, 2017

CDKN2C expression is low in type 2 diabetes and associated with reduced lipid storage capacity in subcutaneous adipose tissue and elevated free fatty acid levels

Pereira, Maria J; Skrtic, S.; Katsogiannos, Petros; Abrahamsson, Niclas et al.

Part of Diabetologia, 2017

Glucose homeostasis and whole-body insulin resistance improved 4 weeks after gastric bypass surgery in type 2 diabetes, whereas adipose tissue metabolism was unchanged

Katsogiannos, Petros; Boersma, Greta J.; Pereira, Maria J; Lundkvist, Per et al.

Part of Diabetologia, 2017

Calcineurin is involved in the regulation of human adipocyte glucose uptake

Fonseca, Ana R. G.; Carvalho, E.; Eriksson, Jan W; Pereira, Maria J

Part of Diabetologia, 2017

Glucagon levels during short-term SGLT2 inhibition are largely regulated by plasma glucose changes

Lundkvist, Per; Pereira, Maria J; Kamble, Prasad G.; Katsogiannos, Petros et al.

Part of Diabetologia, 2017

Glucose uptake in skeletal muscle, brain and visceral adipose tissue assessed with PET/MR strongly predicts whole body glucose uptake during hyperinsulinaemia

Boersma, Greta J.; Heurling, Kerstin; Pereira, Maria J; Johansson, Emil et al.

Part of Diabetologia, 2017

Lipocalin 2 produces insulin resistance and can be upregulated by glucocorticoids in human adipose tissue

Kamble, Prasad G.; Pereira, Maria J.; Sidibeh, Cherno O.; Amini, Sam et al.

Part of Molecular and Cellular Endocrinology, p. 124-132, 2016

• DOI for Lipocalin 2 produces insulin resistance and can be upregulated by glucocorticoids in human adipose tissue

Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors

Pereira, Maria J.; Skrtic, Stanko; Katsogiannos, Petros; Abrahamsson, Niclas et al.

Part of Metabolism, p. 1768-1780, 2016

• DOI for Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of NEFA in type 2 diabetes. Degree of hyperglycemia and adiposity are important factors

Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients

Fryk, Emanuel; Sundelin, Jeanna Perman; Strindberg, Lena; Pereira, Maria J. et al.

Part of Metabolism, p. 998-1006, 2016

• DOI for Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients

Impaired adipose tissue lipid storage, but not altered lipolysis, contributes to elevated levels of free fatty acids in type 2 diabetes

Pereira, Maria J.; Skrtic, S.; Katsogiannos, Petros; Abrahamsson, Niclas et al.

Part of Diabetologia, 2016

Metabolic effects of dapagliflozin QD and exenatide QW in obese adults without diabetes: a 24-week randomised placebo-controlled phase 2 study

Lundkvist, Per; Amini, Sam; Lau Börjesson, Joey; Pereira, Maria J. et al.

Part of Diabetologia, 2016

Skeletal muscle and liver, but not brain, account for impaired glucose utilisation in type 2 diabetes: whole-body PET/MR during hyperinsulinaemic euglycaemic clamp

Boersma, Greta J.; Johansson, Emil; Pereira, Maria J.; Skrtic, S. et al.

Part of Diabetologia, 2016

One year of treatment with dapagliflozin QD plus exenatide QW in obese adults without diabetes: results of an open-label extension study

Eriksson, Jan W.; Lundkvist, Per; Sjöström, C.; Katsogiannos, Petros et al.

Part of Diabetologia, 2016

Role of cannabinoid receptor type 1 in glucocorticoid-induced insulin resistance (IR) and lipolysis regulation in human adipose tissue (AT)

Sidibeh, Cherno O.; Pereira, Maria J.; Börjesson, Joey Lau; Kamble, Prasad G. et al.

Part of Diabetologia, 2016

Evaluation of reference genes for gene expression studies in human brown adipose tissue

Taube, Magdalena; Andersson-Assarsson, Johanna C; Lindberg, Kristin; Pereira, Maria J et al.

Part of Adipocyte, p. 280-285, 2015

• DOI for Evaluation of reference genes for gene expression studies in human brown adipose tissue

Role of cannabinoid receptor type 1 in glucocorticoid-induced lipolysis, insulin resistance and central obesity in human adipose tissue

Sidibeh, Cherno O.; Pereira, Maria João; Börjesson, Joey Lau; Kamble, Prasad G. et al.

Part of Diabetologia, 2015

Role of lipocalin 2 in human adipose tissue metabolism and glucocorticoid-induced insulin resistance

Kamble, Prasad G.; Pereira, Maria João; Sidibeh, Cherno O.; Amini, Sam et al.

Part of Diabetologia, 2015

Microdialysis and proteomics of the subcutaneous interstitial fluid reveals abundance of galectin-1 in type 2 diabetes patients

Fryk, E.; Sundelin, J. Perman; Strindberg, L.; Pereira, Maria João et al.

Part of Diabetologia, 2015

Characterization of Brown Adipose Tissue in the Human Perirenal Depot

Svensson, Per-Arne; Lindberg, Kristin; Hoffmann, Jenny M.; Taube, Magdalena et al.

Part of Obesity, p. 1830-1837, 2014

• DOI for Characterization of Brown Adipose Tissue in the Human Perirenal Depot

Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment

Lopes, P. C.; Fuhrmann, A.; Carvalho, F.; Sereno, J. et al.

Part of Biochemical Pharmacology, p. 61-73, 2014

• DOI for Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment

A Case Report of Improved Metabolic Control After Conversion From Everolimus to Cyclosporin A: Role of Adipose Tissue Mechanisms?

Pereira, Maria J.; Eriksson, Jan W.; Svensson, M. K.

Part of Transplantation Proceedings, p. 2377-2380, 2014

• DOI for A Case Report of Improved Metabolic Control After Conversion From Everolimus to Cyclosporin A: Role of Adipose Tissue Mechanisms?

FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance

Pereira, Maria J; Palming, Jenny; Svensson, Maria K; Rizell, Magnus et al.

Part of Metabolism, p. 1198-1208, 2014

• DOI for FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance

Cyclosporine A and Tacrolimus Reduce the Amount of GLUT4 at the Cell Surface in Human Adipocytes: Increased Endocytosis as a Potential Mechanism for the Diabetogenic Effects of Immunosuppressive Agents

Pereira, Maria João; Palming, Jenny; Rizell, Magnus; Aureliano, Manuel et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2014

• DOI for Cyclosporine A and Tacrolimus Reduce the Amount of GLUT4 at the Cell Surface in Human Adipocytes: Increased Endocytosis as a Potential Mechanism for the Diabetogenic Effects of Immunosuppressive Agents

Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model

Fuhrmann, A.; Lopes, P. C.; Sereno, J.; Pedro, J. et al.

Part of Biochemical Pharmacology, p. 216-228, 2014

• DOI for Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model

Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats

Lopes, Patricia C.; Fuhrmann, Amelia; Sereno, Jose; Espinoza, Daniel O. et al.

Part of Metabolism, p. 702-715, 2014

• DOI for Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats

FKBP5 gene polymorphisms and expression in human adipose tissue are associated with insulin resistance and type 2 diabetes

Pereira, Maria João; Palming, J.; Svensson, M. K.; Rizell, M. et al.

Part of Diabetologia, 2014

Cannabinoid receptor type 1 expression in human adipose tissue is upregulated by glucocorticoids and is associated with insulin resistance

Sidibeh, Cherno O.; Pereira, Maria João; Hammar, M.; Katsogiannos, Petros et al.

Part of Diabetologia, 2014

Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model

Lopes, P; Fuhrmann, A; Sereno, J; Pereira, Maria J et al.

Part of Transplantation Proceedings, p. 1142-1148, 2013

• DOI for Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model

Differences between men and women in the regulation of adipose 11β-HSD1 and in its association with adiposity and insulin resistance

deSchoolmeester, J; Palming, J; Persson, T; Pereira, Maria J et al.

Part of Diabetes, obesity and metabolism, p. 1056-1560, 2013

• DOI for Differences between men and women in the regulation of adipose 11β-HSD1 and in its association with adiposity and insulin resistance

Cyclosporin A and tacrolimus impair dynamics of GLUT4 traffic in insulin-responsive cells

Pereira, Maria João; Palming, J.; Rizell, M.; Aureliano, M. et al.

Part of Diabetologia, 2013

The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue

Pereira, Maria J; Palming, Jenny; Rizell, Magnus; Aureliano, Manuel et al.

Part of Molecular and Cellular Endocrinology, p. 260-269, 2013

• DOI for The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Pereira, Maria J; Palming, Jenny; Rizell, Magnus; Aureliano, Manuel et al.

Part of Molecular and Cellular Endocrinology, p. 96-105, 2012

• DOI for mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Effects of decavanadate and insulin enhancing vanadium compounds on glucose uptake in isolated rat adipocytes

Pereira, Maria João; Carvalho, Eugénia; Eriksson, Jan W; Crans, Debbie C et al.

Part of Journal of Inorganic Biochemistry, p. 1687-1692, 2009

• DOI for Effects of decavanadate and insulin enhancing vanadium compounds on glucose uptake in isolated rat adipocytes

Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue

Ahmed, Fozia; Pereira, Maria João; Aguer, Celine

Part of Environments, 2021

• DOI for Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue
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Integration of whole-body PET/MRI with non-targeted metabolomics provides new insights into insulin sensitivity of various tissues

Diamanti, Klev; Visvanathar, Robin; Pereira, Maria J; Cavalli, Marco et al.

Role of glucocorticoids in adipose tissue fibrosis and interplay between macrophages and adipose cells

Sarsenbayeva, Assel; Pereira, Maria J.; Ahmed, Fozia; Dipta, Priya et al.

Exploration of whole-body PET/MRI and clinical variables in type 2 diabetes for data-driven hypothesis generation

Visvanathar, Robin; Carlbom, Lina; Ekström, Simon; Strand, Robin et al.

Effects of acute GLP-1 receptor activation on the glycemic and neurohormonal responses to meal test after gastric bypass

Almby, Kristina; Wiklund, Urban; Lundqvist, Martin H.; Pereira, Maria J. et al.

Early hormonal adaptations to weight loss: Responses to an oral glucose load following obesity surgery and low-energy diet

Fanni, Giovanni; Hukema, Fleur; Hetty, Susanne; Sundbom, Magnus et al.