Jessica Mwinyi

Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism

Mohammad, Salahuddin; Bussu, Giorgia; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Cephalalgia, p. 1-12, 2025

• DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort

Mwinyi, Jessica; Strippoli, Marie-Pierre F.; Kanders, Sofia H.; Schiöth, Helgi et al.

Part of Translational Psychiatry, 2024

• DOI for Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Mohammad, Salahuddin; Gentreau, Mélissa; Dubol, Manon; Rukh, Gull et al.

Part of Molecular Autism, 2024

• DOI for Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
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Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Part of Scientific Reports, 2024

• DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Lafta, Muataz S.; Mwinyi, Jessica; Affatato, Oreste; Rukh, Gull et al.

Part of Frontiers in Neuroscience, 2024

• DOI for Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism

Mohammad, Salahuddin; Bussu, Giorgia; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Cephalalgia, p. 1-12, 2025

• DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort

Mwinyi, Jessica; Strippoli, Marie-Pierre F.; Kanders, Sofia H.; Schiöth, Helgi et al.

Part of Translational Psychiatry, 2024

• DOI for Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Mohammad, Salahuddin; Gentreau, Mélissa; Dubol, Manon; Rukh, Gull et al.

Part of Molecular Autism, 2024

• DOI for Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
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Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Part of Scientific Reports, 2024

• DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study

Mohammad, Salahuddin; Miguet, Maud; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Scandinavian Journal of Public Health, p. 1248-1257, 2023

• DOI for Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
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Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study

Affatato, Oreste; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B. et al.

Part of BMC Neurology, 2023

• DOI for Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
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Well-being spectrum traits are associated with polygenic scores for autism

Mohammad, Salahuddin; de Ruijter, Markus J. T.; Rukh, Gull; Rask-Andersen, Mathias et al.

Part of Autism Research, p. 1891-1902, 2023

• DOI for Well-being spectrum traits are associated with polygenic scores for autism
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Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study

Affatato, Oreste; Rukh, Gull; Schiöth, Helgi B.; Mwinyi, Jessica

Part of Biomedicines, 2023

• DOI for Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
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Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study

Welander, Nike Zoe; Rukh, Gull; Rask-Andersen, Mathias; Harder, Aster V E et al.

Part of Headache, p. 642-651, 2023

• DOI for Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
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Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Al-Sabri, Mohamed H.; Behare, Neha; Alsehli, Ahmed M.; Berkins, Samuel et al.

Part of Cells, 2022

• DOI for Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
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Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study

Welander, Nike Zoe; Olivo, Gaia; Pisanu, Claudia; Rukh, Gull et al.

Part of Brain and Behavior, 2021

• DOI for Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
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Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank

Affatato, Oreste; Miguet, Maud; Schiöth, Helgi B.; Mwinyi, Jessica

Part of Journal of Headache and Pain, 2021

• DOI for Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank
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Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.

Welander, Nike Zoe; Mwinyi, Jessica; Asif, Sana; Schiöth, Helgi Birgir et al.

Part of Journal of Affective Disorders, p. 733-739, 2021

• DOI for Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.
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Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Rasmusson, Annica J.; Gallwitz, Maike; Soltanabadi, Bardia; Ciuculete, Diana-Maria et al.

Part of Translational Psychiatry, 2021

• DOI for Toll-like receptor 4 methylation grade is linked to depressive symptom severity
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Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank

Pisanu, Claudia; Welander, Nike Zoe; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Biomedicine and Pharmacotherapy, 2021

• DOI for Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
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Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments

Zobdeh, Farzin; Ben Kraiem, Aziza; Attwood, Misty M.; Chubarev, Vladimir N et al.

Part of British Journal of Pharmacology, p. 4588-4607, 2021

• DOI for Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments
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Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes

Boström, Adrian; Chatzittofis, Andreas; Ciuculete, Diana-Maria; Flanagan, John N. et al.

Part of Epigenetics, p. 145-160, 2020

• DOI for Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes
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meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

Ciuculete, Diana-Maria; Voisin, Sarah; Kular, Lara; Jonsson, Jörgen et al.

Part of Clinical Epigenetics, 2020

• DOI for meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes
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A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants

Kanders, Sofia H.; Pisanu, Claudia; Bandstein, Marcus; Jonsson, Jörgen et al.

Part of Drug development research, p. 102-113, 2020

• DOI for A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants
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Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression

Ciuculete, Diana Maria; Voisin, Sarah; Kular, Lara; Welihinda, Nipuni et al.

Part of Epigenetics, p. 646-663, 2020

• DOI for Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression
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Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Pisanu, Claudia; Lundin, Emma; Preisig, Martin; Gholam-Rezaee, Mehdi et al.

Part of Cephalalgia, p. 347-356, 2020

• DOI for Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Plasma levels of leptin and adiponectin and depressive symptoms in young adults

Syk, Mikaela; Ellström, Sofie; Mwinyi, Jessica; Schiöth, Helgi B. et al.

Part of Psychiatry Research, p. 1-7, 2019

• DOI for Plasma levels of leptin and adiponectin and depressive symptoms in young adults
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Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents

Ciuculete, Diana-Maria; Boström, Adrian E.; Tuunainen, Anna-Kaisa; Sohrabi, Farah et al.

Part of Journal of Psychiatric Research, p. 44-51, 2018

• DOI for Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents
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Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene

Skuladottir, Gudrun Valgerdur; Oskarsdottir, Harpa; Pisanu, Claudia; Sjodin, Marcus et al.

Part of Diabetes, Metabolic Syndrome and Obesity, p. 611-618, 2018

• DOI for Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene
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A genetic risk score is differentially associated with migraine with and without aura

Pisanu, Claudia; Preisig, Martin; Castelao, Enrique; Glaus, Jennifer et al.

Part of Human Genetics, p. 999-1008, 2017

• DOI for A genetic risk score is differentially associated with migraine with and without aura
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Response to Leusink et al.

Ciuculete, Diana-Maria; Schiöth, Helgi B.; Mwinyi, Jessica

Part of Clinical Genetics, p. 566-566, 2017

• DOI for Response to Leusink et al.

A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score

Ciuculete, Diana-Maria; Boström, Adrian E.; Voisin, Sarah; Philipps, H. et al.

Part of Translational Psychiatry, 2017

• DOI for A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score
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A genetic risk score is significantly associated with statin therapy response in the elderly population

Ciuculete, Diana-Maria; Bandstein, Marcus; Benedict, Christian; Waeber, G. et al.

Part of Clinical Genetics, p. 379-385, 2017

• DOI for A genetic risk score is significantly associated with statin therapy response in the elderly population

High leptin levels are associated with migraine with aura

Pisanu, Claudia; Preisig, Martin; Castelao, Enrique; Glaus, Jennifer et al.

Part of Cephalalgia, p. 435-441, 2017

• DOI for High leptin levels are associated with migraine with aura

A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

Xu, Jiayue; Boström, Adrian; Saeed, Mohamed; Dubey, Raghvendra K. et al.

Part of Medicine, 2017

• DOI for A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Mwinyi, Jessica; Boström, Adrian; Pisanu, Claudia; Murphy, Susan K. et al.

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 314-323, 2017

• DOI for NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

Mwinyi, Jessica; Boström, Adrian; Fehrer, I.; Othman, A. et al.

Part of PLOS ONE, 2017

• DOI for Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus
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A MIR4646 associated methylation locus is hypomethylated in adolescent depression

Boström, Adrian; Ciuculete, Diana-Maria; Attwood, Misty M.; Krattinger, Regina et al.

Part of Journal of Affective Disorders, p. 117-128, 2017

• DOI for A MIR4646 associated methylation locus is hypomethylated in adolescent depression
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Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men

Mwinyi, Jessica; Pisanu, Claudia; Castelao, Enrique; Stringhini, Silvia et al.

Part of Women's health issues, p. 302-307, 2017

• DOI for Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men

A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery

Bandstein, Marcus; Mwinyi, Jessica; Ernst, Barbara; Thurnheer, Martin et al.

Part of Scandinavian Journal of Gastroenterology, p. 1050-1055, 2016

• DOI for A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery
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microRNA-192 suppresses the expression of the farnesoid X receptor

Krattinger, Regina; Boström, Adrian; Schiöth, Helgi B.; Thasler, Wolfgang E. et al.

Part of American Journal of Physiology - Gastrointestinal and Liver Physiology, 2016

• DOI for microRNA-192 suppresses the expression of the farnesoid X receptor

One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men

Skuladottir, Gudrun Valgerdur; Nilsson, Emil Karl; Mwinyi, Jessica; Schiöth, Helgi Birgir

Part of Lipids in Health and Disease, 2016

• DOI for One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men
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Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

Nilsson, Emil K.; Boström, Adrian E.; Mwinyi, Jessica; Schiöth, Helgi B.

Part of Omics, p. 334-342, 2016

• DOI for Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension

Boström, Adrian E.; Mwinyi, Jessica; Voisin, Sarah; Wu, Wenting et al.

Part of BMC Medical Genomics, 2016

• DOI for Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension
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A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery

Bandstein, Marcus; Voisin, Sarah; Nilsson, Emil; Schultes, Bernd et al.

Part of Obesity Surgery, p. 2183-2189, 2016

• DOI for A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery
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A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease

Schiöth, Helgi B.; Boström, Adrian; Murphy, Susan K.; Erhart, Wiebke et al.

Part of BMC Genomics, 2016

• DOI for A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease
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Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Krattinger, Regina; Boström, Adrian; Lee, Serene M. L.; Thasler, Wolfgang E. et al.

Part of Life Sciences, p. 47-56, 2016

• DOI for Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes
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Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Nilsson, Emil; Ernst, Barbara; Voisin, Sarah; Sällman Almén, Markus et al.

Part of PLOS ONE, 2015

• DOI for Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients
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Chenodeoxycholic acid induced changes in the expression of microRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Kullak-Ublick, Gerd A.; Krattinger, Regina; Lee, Serene M.; Thasler, Wolfgang E. et al.

Part of Hepatology, 2015

Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Lafta, Muataz S.; Mwinyi, Jessica; Affatato, Oreste; Rukh, Gull et al.

Part of Frontiers in Neuroscience, 2024

• DOI for Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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The Epigenetics of Migraine

Zobdeh, Farzin; Eremenko, Ivan I.; Akan, Mikail A.; Tarasov, Vadim V. et al.

Part of International Journal of Molecular Sciences, 2023

• DOI for The Epigenetics of Migraine
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Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health

Ciuculete, Diana-Maria; Mwinyi, Jessica; Schiöth, Helgi B.

Part of International Journal of Molecular Sciences, 2022

• DOI for Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health
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Pharmacogenetics and Pain Treatment with a Focus on Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Antidepressants: A Systematic Review

Zobdeh, Farzin; Eremenko, Ivan I.; Akan, Mikail A.; Tarasov, Vadim V. et al.

Part of Pharmaceutics, 2022

• DOI for Pharmacogenetics and Pain Treatment with a Focus on Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Antidepressants: A Systematic Review
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Pharmacogenetics in Primary Headache Disorders

Belyaeva, Irina I.; Subbotina, Anna G.; Eremenko, Ivan I.; Tarasov, Vadim V. et al.

Part of Frontiers in Pharmacology, 2022

• DOI for Pharmacogenetics in Primary Headache Disorders
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The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential

Al-Sabri, Mohamed H.; Nikpour, Maryam; Clemensson, Laura Emily; Attwood, Misty M. et al.

Part of Cell & Bioscience, 2022

• DOI for The regulatory role of AP-2 beta in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential
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High efficacy of onabotulinumtoxinA treatment in patients with comorbid migraine and depression: a meta-analysis

Affatato, Oreste; Moulin, Thiago; Pisanu, Claudia; Babasieva, Victoria S. et al.

Part of Journal of Translational Medicine, 2021

• DOI for High efficacy of onabotulinumtoxinA treatment in patients with comorbid migraine and depression: a meta-analysis
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Therapy response prediction in major depressive disorder: current and novel genomic markers influencing pharmacokinetics and pharmacodynamics

Shalimova, Alena; Babasieva, Viktoria; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Part of Pharmacogenomics (London), p. 485-503, 2021

• DOI for Therapy response prediction in major depressive disorder: current and novel genomic markers influencing pharmacokinetics and pharmacodynamics
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Antidepressant therapy, subtypes of major depressive disorder and the risk for weight gain: effect on body mass index, waist circumference, and fat mass

Mwinyi, Jessica; Kanders, Sofia H.; Strippoli, Marie-Pierre; Schiöth, Helgi B. et al.