Filip Mihalic

Defining short linear motif binding determinants by phage display-based deep mutational scanning

Benz, Caroline; Maasen, Lars; Simonetti, Leandro; Mihalič, Filip et al.

Part of Protein Science, 2025

• DOI for Defining short linear motif binding determinants by phage display-based deep mutational scanning
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Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes

Mihalič, Filip; Arcila, Dahiana; Pettersson, Mats; Farkhondehkish, Pouria et al.

Part of Molecular biology and evolution, 2024

• DOI for Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes
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Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions

Johansson, Josefin; Lidéus, Sarah; Frykholm, Carina; Gunnarsson, Cecilia et al.

Part of European Journal of Human Genetics, 2024

• DOI for Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions
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The evolutionary and molecular history of a chikungunya virus outbreak lineage

Krambrich, Janina; Mihalič, Filip; Gaunt, Michael W.; Bohlin, Jon et al.

Part of PLoS Neglected Tropical Diseases, 2024

• DOI for The evolutionary and molecular history of a chikungunya virus outbreak lineage
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Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

Mihalič, Filip; Simonetti, Leandro; Giudice, Girolamo; Rubin Sander, Marie et al.

Part of Nature Communications, 2023

• DOI for Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
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Defining short linear motif binding determinants by phage display-based deep mutational scanning

Benz, Caroline; Maasen, Lars; Simonetti, Leandro; Mihalič, Filip et al.

Part of Protein Science, 2025

• DOI for Defining short linear motif binding determinants by phage display-based deep mutational scanning
• Download full text (pdf) of Defining short linear motif binding determinants by phage display-based deep mutational scanning

Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes

Mihalič, Filip; Arcila, Dahiana; Pettersson, Mats; Farkhondehkish, Pouria et al.

Part of Molecular biology and evolution, 2024

• DOI for Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes
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Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions

Johansson, Josefin; Lidéus, Sarah; Frykholm, Carina; Gunnarsson, Cecilia et al.

Part of European Journal of Human Genetics, 2024

• DOI for Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions
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The evolutionary and molecular history of a chikungunya virus outbreak lineage

Krambrich, Janina; Mihalič, Filip; Gaunt, Michael W.; Bohlin, Jon et al.

Part of PLoS Neglected Tropical Diseases, 2024

• DOI for The evolutionary and molecular history of a chikungunya virus outbreak lineage
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Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

Mihalič, Filip; Simonetti, Leandro; Giudice, Girolamo; Rubin Sander, Marie et al.

Part of Nature Communications, 2023

• DOI for Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
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Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif-mediated interactions

Mihalič, Filip; Åberg, Emma; Farkhondehkish, Pouria; Theys, Niels et al.

Part of Protein Science, 2023

• DOI for Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif-mediated interactions
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Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Mihalic, Filip; Benz, Caroline; Kassa, Eszter; Lindqvist, Richard et al.

Part of Nature Communications, 2023

• DOI for Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
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Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions

Kassa, Eszter; Jamshidi, Sara; Mihalič, Filip; Simonetti, Leandro et al.

Part of Analytical Biochemistry, 2023

• DOI for Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions
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Proteome-scale mapping of binding sites in the unstructured regions of the human proteome

Benz, Caroline; Ali, Muhammad; Krystkowiak, Izabella; Simonetti, Leandro et al.

Part of Molecular Systems Biology, 2022

• DOI for Proteome-scale mapping of binding sites in the unstructured regions of the human proteome
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Monoclonal antibodies binding data for SARS-CoV-2 proteins

Mishra, Nawneet; Teyra, Joan; Boytz, RuthMabel; Miersch, Shane et al.

Part of Data in Brief, 2022

• DOI for Monoclonal antibodies binding data for SARS-CoV-2 proteins
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Development of Monoclonal Antibodies to Detect for SARS-CoV-2 Proteins

Mishra, Nawneet; Teyra, Joan; Boytz, RuthMabel; Miersch, Shane et al.

Part of Journal of Molecular Biology, 2022

• DOI for Development of Monoclonal Antibodies to Detect for SARS-CoV-2 Proteins

Discovery of an allosteric ligand binding site in SMYD3 lysine methyltransferase

Talibov, Vladimir O; Fabini, Edoardo; FitzGerald, Edward; Tedesco, Daniele et al.

Part of ChemBioChem, p. 1597-1608, 2021

• DOI for Discovery of an allosteric ligand binding site in SMYD3 lysine methyltransferase
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Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

Kruse, Thomas; Benz, Caroline; Garvanska, Dimitriya H.; Lindqvist, Richard et al.

Part of Nature Communications, 2021

• DOI for Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
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Unveiling the Biochemistry of the Epigenetic Regulator SMYD3

Fabini, Edoardo; Talibov, Vladimir O; Mihalic, Filip; Naldi, Marina et al.

Part of Biochemistry, p. 3634-3645, 2019

• DOI for Unveiling the Biochemistry of the Epigenetic Regulator SMYD3

Evolution and viral mimicry of short linear motif-mediated interactions

Mihalič, Filip

2022

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Loss-of-affinity mutations and new interaction motifs underlie a dynamic evolution of the p53/MDM2 interaction in teleosts

Mihalic, Filip; Arcila, Dahiana; Pettersson, Mats; Farkhondehkish, Pouria et al.

Evolution of binding affinity between p53 and MDM2 across the animal kingdom

Åberg, Emma; Mihalic, Filip; Farkhondehkish, Pouria; Theys, Niels et al.

Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions

Kassa, Eszter; Jamshidi, Sara; Mihalič, Filip; Simonetti, Leandro et al.

• DOI for Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions