Henrik Land

Investigating the native functions of [NiFe]-carbon monoxide dehydrogenases through genomic context analysis

Böhm, Maximilian; Land, Henrik

Part of eLIFE, 2026

• DOI for Investigating the native functions of [NiFe]-carbon monoxide dehydrogenases through genomic context analysis

Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Schumann, Conrad; Kugler, Amit; Shah, Bhavik Ashwin; Berggren, Gustav et al.

Part of Microbial Cell Factories, 2025

• DOI for Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803
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A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people

Welsh, Caitlin; Cabotaje, Princess R.; Marcelino, Vanessa R.; Watts, Thomas D. et al.

Part of Nature Microbiology, p. 2686-2701, 2025

• DOI for A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people
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Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Schumann, Conrad; Kugler, Amit; Shah, Bhavik Ashwin; Berggren, Gustav et al.

Part of Microbial Cell Factories, 2025

• DOI for Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups

Senger, Moritz; Schumann, Conrad; Cabotaje, Princess R.; Zamader, Afridi et al.

Part of Physical Chemistry, Chemical Physics - PCCP, p. 9864-9875, 2025

• DOI for Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
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Investigating the native functions of [NiFe]-carbon monoxide dehydrogenases through genomic context analysis

Böhm, Maximilian; Land, Henrik

Part of eLIFE, 2026

• DOI for Investigating the native functions of [NiFe]-carbon monoxide dehydrogenases through genomic context analysis

Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Schumann, Conrad; Kugler, Amit; Shah, Bhavik Ashwin; Berggren, Gustav et al.

Part of Microbial Cell Factories, 2025

• DOI for Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803
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A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people

Welsh, Caitlin; Cabotaje, Princess R.; Marcelino, Vanessa R.; Watts, Thomas D. et al.

Part of Nature Microbiology, p. 2686-2701, 2025

• DOI for A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people
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Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Schumann, Conrad; Kugler, Amit; Shah, Bhavik Ashwin; Berggren, Gustav et al.

Part of Microbial Cell Factories, 2025

• DOI for Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups

Senger, Moritz; Schumann, Conrad; Cabotaje, Princess R.; Zamader, Afridi et al.

Part of Physical Chemistry, Chemical Physics - PCCP, p. 9864-9875, 2025

• DOI for Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups
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Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H₂ Evolution and O₂ Tolerance through Rational Design of [FeFe] Hydrogenase

Cabotaje, Princess R.; Sekretareva, Alina; Senger, Moritz; Huang, Ping et al.

Part of Journal of the American Chemical Society, p. 4654-4666, 2025

• DOI for Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H₂ Evolution and O₂ Tolerance through Rational Design of [FeFe] Hydrogenase
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Secondary structure changes as the potential H₂ sensing mechanism of group D [FeFe]-hydrogenases

Voloshyn, Ivan; Schumann, Conrad; Cabotaje, Princess R.; Zamader, Afridi et al.

Part of Chemical Communications, p. 10914-10917, 2024

• DOI for Secondary structure changes as the potential H₂ sensing mechanism of group D [FeFe]-hydrogenases
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Minimal and hybrid hydrogenases are active from archaea

Greening, Chris; Cabotaje, Princess R.; Valentin Alvarado, Luis E.; Leung, Pok Man et al.

Part of Cell, 2024

• DOI for Minimal and hybrid hydrogenases are active from archaea
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Photobiocatalytic CO₂ reduction into CO by organic nanorod-carbon monoxide dehydrogenase assemblies: surfactant matters

Pavliuk, Mariia V.; Böhm, Maximilian; Wilhelmsen, Janna; Hardt, Steffen et al.

Part of Chemical Science, p. 16789-16795, 2024

• DOI for Photobiocatalytic CO₂ reduction into CO by organic nanorod-carbon monoxide dehydrogenase assemblies: surfactant matters
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Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase

Cabotaje, Princess R.; Walter, Kaija; Zamader, Afridi; Huang, Ping et al.

Part of ACS Catalysis, p. 10435-10446, 2023

• DOI for Probing Substrate Transport Effects on Enzymatic Hydrogen Catalysis: An Alternative Proton Transfer Pathway in Putatively Sensory [FeFe] Hydrogenase
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Enantioselective Synthesis of Pharmaceutically Relevant Bulky Arylbutylamines Using Engineered Transaminases

Sheludko, Yuriy; Slagman, Sjoerd; Gittings, Samantha; Charnock, Simon J. et al.

Part of Advanced Synthesis and Catalysis, p. 2972-2981, 2022

• DOI for Enantioselective Synthesis of Pharmaceutically Relevant Bulky Arylbutylamines Using Engineered Transaminases
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Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems

Lorenzi, Marco; Gamache, Mira T.; Redman, Holly J.; Land, Henrik et al.

Part of ACS Sustainable Chemistry and Engineering, p. 10760-10767, 2022

• DOI for Light-Driven [FeFe] Hydrogenase Based H-2 Production in E. coli: A Model Reaction for Exploring E. coli Based Semiartificial Photosynthetic Systems
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Semi-synthetic hydrogenases—in vitro and in vivo applications

Meszaros, Livia S.; Land, Henrik; Redman, Holly J.; Berggren, Gustav

Part of Current Opinion in Green and Sustainable Chemistry, 2021

• DOI for Semi-synthetic hydrogenases—in vitro and in vivo applications
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Reversible or Irreversible Catalysis of H⁺/H₂ Conversion by FeFe Hydrogenases

Fasano, Andrea; Land, Henrik; Fourmond, Vincent; Berggren, Gustav et al.

Part of Journal of the American Chemical Society, p. 20320-20325, 2021

• DOI for Reversible or Irreversible Catalysis of H⁺/H₂ Conversion by FeFe Hydrogenases

Semisynthetic [FeFe]-hydrogenase with stable expression and H₂ production capacity in a photosynthetic microbe

Wegelius, Adam; Land, Henrik; Berggren, Gustav; Lindblad, Peter

Part of Cell Reports Physical Science, 2021

• DOI for Semisynthetic [FeFe]-hydrogenase with stable expression and H₂ production capacity in a photosynthetic microbe
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Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture

Land, Henrik; Sekretaryova, Alina N.; Huang, Ping; Redman, Holly J. et al.

Part of Chemical Science, p. 12789-12801, 2020

• DOI for Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
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The maturase HydF enables [FeFe] hydrogenase assembly via transient, cofactor-dependent interactions

Németh, Brigitta; Land, Henrik; Magnuson, Ann; Hofer, Anders et al.

Part of Journal of Biological Chemistry, p. 11891-11901, 2020

• DOI for The maturase HydF enables [FeFe] hydrogenase assembly via transient, cofactor-dependent interactions
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Engineering the Active Site of an (S)-Selective Amine Transaminase for Acceptance of Doubly Bulky Primary Amines

Land, Henrik; Ruggieri, Federica; Szekrenyi, Anna; Fessner, Wolf-Dieter et al.

Part of Advanced Synthesis and Catalysis, p. 812-821, 2020

• DOI for Engineering the Active Site of an (S)-Selective Amine Transaminase for Acceptance of Doubly Bulky Primary Amines
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Current State of [FeFe]-Hydrogenase Research: Biodiversity and Spectroscopic Investigations

Land, Henrik; Senger, Moritz; Berggren, Gustav; Stripp, Sven T.

Part of ACS Catalysis, p. 7069-7086, 2020

• DOI for Current State of [FeFe]-Hydrogenase Research: Biodiversity and Spectroscopic Investigations

Carbon Dots and [FeFe] Hydrogenase Biohybrid Assemblies for Efficient Light-Driven Hydrogen Evolution

Hola, Katerina; Pavliuk, Mariia V.; Nemeth, Brigitta; Huang, Ping et al.

Part of ACS Catalysis, p. 9943-9952, 2020

• DOI for Carbon Dots and [FeFe] Hydrogenase Biohybrid Assemblies for Efficient Light-Driven Hydrogen Evolution
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Discovery of novel [FeFe]-hydrogenases for biocatalytic H-2-production

Land, Henrik; Ceccaldi, Pierre; Meszaros, Livia S.; Lorenzi, Marco et al.

Part of Chemical Science, p. 9941-9948, 2019

• DOI for Discovery of novel [FeFe]-hydrogenases for biocatalytic H-2-production
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B-factor Guided Proline Substitutions in Chromobacterium violaceum Amine Transaminase: Evaluation of the Proline Rule as a Method for Enzyme Stabilization

Land, Henrik; Campillo-Brocal, Jonatan C.; Humble, Maria Svedendahl; Berglund, Per

Part of ChemBioChem, p. 1297-1304, 2019

• DOI for B-factor Guided Proline Substitutions in Chromobacterium violaceum Amine Transaminase: Evaluation of the Proline Rule as a Method for Enzyme Stabilization
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Studying [FeFe] hydrogenase maturation and the nature of the HydF-HydA interaction

Németh, Brigitta; Land, Henrik; Magnuson, Ann; Hofer, Anders et al.

Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Kugler, Amit; Schumann, Conrad; Land, Henrik; Blikstad, Cecilia et al.