Susanne Lager
Senior Lecturer/Associate Professor at Department of Women's and Children's Health; Obstetric and Reproductive Health Research
- E-mail:
- susanne.lager@uu.se
- Visiting address:
- MTC-huset, Dag Hammarskjölds väg 14B, 1 tr
752 37 Uppsala - Postal address:
- Akademiska sjukhuset
751 85 UPPSALA
Deputy Director at The Centre for Reproductive Biology in Uppsala (CRU)
- Postal address:
- Box 7054
750 07 UPPSALA
- ORCID:
- 0000-0003-3556-065X
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Biography
Susanne Lager is a Senior Lecture in laboratory science at the Department of Women's and Children's Health, Uppsala University, Sweden. Lager has a master's degree in biology (specialization in molecular biology) and a PhD in physiology from the University of Gothenburg, Sweden. After undertaking postdoctoral training at the University of Texas Health Science Center at San Antonio (USA) and at the University of Cambridge (UK), Lager returned to Sweden in 2018.
Research
Susanne Lager's research focuses mainly on pregnancy complications and placenta using a range of in vitro and molecular biology approaches. Her current projects are investigating connections between early pregnancy maternal proteomics and pregnancy outcomes, alcohol / drug abuse during pregnancy and placental function, as well as viral infections and pregnancy complications. A list of her publications can be found here (PubMed). Currently, Lager is the main supervisor of three PhD students and co-supervising four PhD students.
Lager is a member of an international collaboration to improve outcomes for preeclampsia.
Publications
Selection of publications
- Spatial transcriptomics of human placentas reveal distinct RNA patterns associated with morphology and preeclampsia (2023)
- Placental Streptococcus agalactiae DNA is associated with neonatal unit admission and foetal pro-inflammatory cytokines in term infants (2023)
- Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia (2020)
- Abnormal placental CD8+ T cell infiltration is a feature of fetal growth restriction and pre-eclampsia. (2020)
- Human placenta has no microbiome but can contain potential pathogens (2019)
Recent publications
- Does Developing Interpregnancy Hypertension Affect the Recurrence Risk of Preeclampsia? (2024)
- Novel Associations Between Mid-Pregnancy Cardiovascular Biomarkers and Preeclampsia: An Explorative Nested Case-Control Study (2024)
- Biomarkers associated with cardiovascular disease in women with spontaneous preterm birth (2024)
- Differential gene expression in two consecutive pregnancies between same sex siblings and implications on maternal constraint (2024)
- Epidemiologically relevant phthalates affect human endometrial cells in vitro through cell specific gene expression changes related to the cytoskeleton and mitochondria (2024)
All publications
Articles
- Does Developing Interpregnancy Hypertension Affect the Recurrence Risk of Preeclampsia? (2024)
- Novel Associations Between Mid-Pregnancy Cardiovascular Biomarkers and Preeclampsia: An Explorative Nested Case-Control Study (2024)
- Biomarkers associated with cardiovascular disease in women with spontaneous preterm birth (2024)
- Differential gene expression in two consecutive pregnancies between same sex siblings and implications on maternal constraint (2024)
- Epidemiologically relevant phthalates affect human endometrial cells in vitro through cell specific gene expression changes related to the cytoskeleton and mitochondria (2024)
- Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences (2024)
- Spatial transcriptomics of human placentas reveal distinct RNA patterns associated with morphology and preeclampsia (2023)
- Placental Streptococcus agalactiae DNA is associated with neonatal unit admission and foetal pro-inflammatory cytokines in term infants (2023)
- Study protocol (2023)
- Early Mid-pregnancy Blood-Based Proteins as Possible Biomarkers of Increased Infant Birth Size in Sex-Stratified Analyses (2023)
- Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro (2023)
- Alcohol exposure prior to pregnancy-does hazardous consumption affect placenta- and inflammatory-mediated pregnancy outcomes? A Swedish population-based cohort study (2022)
- Elevated mid-pregnancy plasma levels of angiotensin-converting enzyme 2 in women prior to the development of preeclampsia. (2022)
- Maternal prenatal depressive symptoms and toddler behavior (2022)
- Alcohol consumption habits and associations with anxiety or depressive symptoms postpartum in women with high socioeconomic status in Sweden (2022)
- Evolutionary history of endogenous Human Herpesvirus 6 reflects human migration out of Africa (2021)
- Pregnancy-related hormones and COMT genotype (2021)
- DNA methylation in cord blood in association with prenatal depressive symptoms (2021)
- Study protocol (2021)
- Placental glucocorticoid receptors are not affected by maternal depression or SSRI treatment. (2020)
- Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia (2020)
- Abnormal placental CD8+ T cell infiltration is a feature of fetal growth restriction and pre-eclampsia. (2020)
- Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like rats. (2020)
- Cohort profile (2019)
- Human placenta has no microbiome but can contain potential pathogens (2019)
- The effect of antenatal depression and antidepressant treatment on placental tissue (2019)
- Blood plasma metabolic profiling of pregnant women with antenatal depressive symptoms (2019)
- Circulating antimüllerian hormone and steroid hormone levels remain high in pregnant women with polycystic ovary syndrome at term (2019)
- Hyperandrogenism and insulin resistance-induced fetal loss (2019)
- Biomarkers for cardiovascular disease in women with spontaneous preterm birth – A case control study
- Effect of phthalate metabolite MEHHP on mitochondrial metabolism and dynamics in human endometrial stromal cells