Xinran Zhao
Visiting researcher at Department of Medical Biochemistry and Microbiology; Infection and Immunity; Gunnar Pejler
- E-mail:
- Xinran.Zhao@imbim.uu.se
- Visiting address:
- BMC
Husargatan 3
752 37 UPPSALA - Postal address:
- Box 582
751 23 UPPSALA
Keywords
- Mast cells
- Chymase
- Cell morphology
Biography
I am an immunologist and cell biologist with interdisciplinary training in inflammation, structural cell biology and biochemistry.
Research
My core research interest lies in understanding how cells change shape in diverse biological contexts. Cell morphology underpins tissue architecture and organ function, but the regulatory mechanisms connecting signaling pathways to shape changes remain poorly defined.
My research carved out a new niche by examining how mast cell proteases, particularly chymase, affect the structure and behavior of airway-resident cells, moving beyond the conventional immunoregulatory functions of these proteases.
Media
Linkedin profile:
https://www.linkedin.com/in/xinranzhaott
You can also find me at:
Publications
Selection of publications
Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024
- DOI for Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
- Download full text (pdf) of Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
Part of Journal of Allergy and Clinical Immunology, p. 718-727, 2022
- DOI for Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
- Download full text (pdf) of Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
Part of Journal of Allergy and Clinical Immunology, p. 1534-1544, 2022
- DOI for Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells
- Download full text (pdf) of Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells
Recent publications
Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024
- DOI for Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
- Download full text (pdf) of Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
Part of Journal of Allergy and Clinical Immunology, p. 940-951, 2024
- DOI for Blockade of endolysosomal acidification suppresses TLR3-mediated proinflammatory signaling in airway epithelial cells
- Download full text (pdf) of Blockade of endolysosomal acidification suppresses TLR3-mediated proinflammatory signaling in airway epithelial cells
Effects of mast cell proteases on lung structural cells: Implications for asthma
2024
Part of Journal of Allergy and Clinical Immunology, p. 718-727, 2022
- DOI for Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
- Download full text (pdf) of Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
Part of Journal of Allergy and Clinical Immunology, p. 1534-1544, 2022
- DOI for Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells
- Download full text (pdf) of Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells
All publications
Articles in journal
Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 2524-2527, 2024
- DOI for Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
- Download full text (pdf) of Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells
Part of Journal of Allergy and Clinical Immunology, p. 940-951, 2024
- DOI for Blockade of endolysosomal acidification suppresses TLR3-mediated proinflammatory signaling in airway epithelial cells
- Download full text (pdf) of Blockade of endolysosomal acidification suppresses TLR3-mediated proinflammatory signaling in airway epithelial cells
Part of Journal of Allergy and Clinical Immunology, p. 718-727, 2022
- DOI for Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
- Download full text (pdf) of Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma
Part of Journal of Allergy and Clinical Immunology, p. 1534-1544, 2022
- DOI for Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells
- Download full text (pdf) of Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells
Mast cell chymase has a negative impact on human osteoblasts
Part of Matrix Biology, p. 1-19, 2022
- DOI for Mast cell chymase has a negative impact on human osteoblasts
- Download full text (pdf) of Mast cell chymase has a negative impact on human osteoblasts