Alexandru Dasu
Professor at Department of Immunology, Genetics and Pathology; Clinical units; Skandion Clinic
- E-mail:
- alexandru.dasu@igp.uu.se
- Visiting address:
- Skandionkliniken
von Kraemers allé 26
752 37 Uppsala - Postal address:
- Kommunalförbundet Skandionkliniken
Box 6374
751 36 Uppsala
- E-mail:
- alexandru.dasu@igp.uu.se
- Visiting address:
- Skandionkliniken
von Kraemers allé 26
752 37 UPPSALA - Postal address:
- Kommunalförbundet Skandionkliniken
Box 6374
751 36 UPPSALA
Publications
Recent publications
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Part of Journal of Nuclear Medicine, p. 374-382, 2026
- DOI for Biologically individualized radiotherapy based on PET: A novel approach to treatment optimization of head and neck cancer
- Download full text (pdf) of Biologically individualized radiotherapy based on PET: A novel approach to treatment optimization of head and neck cancer
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Part of Radiotherapy and Oncology, 2026
- DOI for Radiation therapy in adolescents and young adults (AYA): contemporary evidence on utilization, outcomes, late toxicities, and second malignant neoplasms – A comprehensive systematic review and synthesis
- Download full text (pdf) of Radiation therapy in adolescents and young adults (AYA): contemporary evidence on utilization, outcomes, late toxicities, and second malignant neoplasms – A comprehensive systematic review and synthesis
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Part of Physica medica (Testo stampato), 2026
- DOI for Accounting for out-of-field dose and second cancer risk in classical Hodgkin lymphoma: A comprehensive comparison of proton and photon therapy using whole-body phantom
- Download full text (pdf) of Accounting for out-of-field dose and second cancer risk in classical Hodgkin lymphoma: A comprehensive comparison of proton and photon therapy using whole-body phantom
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Part of Physics and Imaging in Radiation Oncology, 2026
- DOI for Effects of breath-hold reproducibility on proton and photon lung cancer stereotactic body radiotherapy
- Download full text (pdf) of Effects of breath-hold reproducibility on proton and photon lung cancer stereotactic body radiotherapy
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Part of Physica medica (Testo stampato), 2026
- DOI for Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
- Download full text (pdf) of Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
All publications
Articles in journal
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Part of Journal of Nuclear Medicine, p. 374-382, 2026
- DOI for Biologically individualized radiotherapy based on PET: A novel approach to treatment optimization of head and neck cancer
- Download full text (pdf) of Biologically individualized radiotherapy based on PET: A novel approach to treatment optimization of head and neck cancer
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Part of Physica medica (Testo stampato), 2026
- DOI for Accounting for out-of-field dose and second cancer risk in classical Hodgkin lymphoma: A comprehensive comparison of proton and photon therapy using whole-body phantom
- Download full text (pdf) of Accounting for out-of-field dose and second cancer risk in classical Hodgkin lymphoma: A comprehensive comparison of proton and photon therapy using whole-body phantom
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Part of Physics and Imaging in Radiation Oncology, 2026
- DOI for Effects of breath-hold reproducibility on proton and photon lung cancer stereotactic body radiotherapy
- Download full text (pdf) of Effects of breath-hold reproducibility on proton and photon lung cancer stereotactic body radiotherapy
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Part of Physica medica (Testo stampato), 2026
- DOI for Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
- Download full text (pdf) of Personalized organ dose assessment from CT imaging during proton therapy for classical Hodgkin lymphoma patients
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Part of Physics in Medicine and Biology, 2025
- DOI for Robust treatment planning and displacement vector field editing for the probabilistic evaluation of proton radiotherapy of small lung tumors
- Download full text (pdf) of Robust treatment planning and displacement vector field editing for the probabilistic evaluation of proton radiotherapy of small lung tumors
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Part of Physica medica (Testo stampato), 2025
- DOI for Patterns of practice of image guided particle therapy for brain tumours: A site specific multi-institutional survey of the European particle therapy network
- Download full text (pdf) of Patterns of practice of image guided particle therapy for brain tumours: A site specific multi-institutional survey of the European particle therapy network
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Part of Physica medica (Testo stampato), 2025
- DOI for Radiation protection in proton therapy: Insights from a multi-institutional survey and experimental measurements within the SINFONIA project
- Download full text (pdf) of Radiation protection in proton therapy: Insights from a multi-institutional survey and experimental measurements within the SINFONIA project
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Part of Physica medica (Testo stampato), 2025
- DOI for Patterns of practice of image guided particle therapy for extremity tumours: A site specific multi-institutional survey of European particle therapy network
- Download full text (pdf) of Patterns of practice of image guided particle therapy for extremity tumours: A site specific multi-institutional survey of European particle therapy network
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In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup
Part of Clinical and Translational Radiation Oncology, 2025
- DOI for In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup
- Download full text (pdf) of In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup
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Part of Physics and Imaging in Radiation Oncology, 2025
- DOI for Recommendations for reporting and evaluating proton therapy beyond dose and constant relative biological effectiveness
- Download full text (pdf) of Recommendations for reporting and evaluating proton therapy beyond dose and constant relative biological effectiveness
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Part of Physica medica (Testo stampato), 2025
- DOI for Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
- Download full text (pdf) of Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
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Part of Neurosurgery, p. 174-182, 2024
- DOI for Impact of the Mean Cochlear Biologically Effective Dose on Hearing Preservation After Stereotactic Radiosurgery for Vestibular Schwannoma: A Retrospective Longitudinal Analysis
- Download full text (pdf) of Impact of the Mean Cochlear Biologically Effective Dose on Hearing Preservation After Stereotactic Radiosurgery for Vestibular Schwannoma: A Retrospective Longitudinal Analysis
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Part of Physica medica (Testo stampato), 2024
- DOI for Dosimetric evaluation of intensity modulated photon versus proton reirradiation of head and neck cancer
- Download full text (pdf) of Dosimetric evaluation of intensity modulated photon versus proton reirradiation of head and neck cancer
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Part of Neurosurgery, p. 423-430, 2024
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Towards a European prospective data registry for particle therapy
Part of Radiotherapy and Oncology, 2024
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Part of Physica medica (Testo stampato), 2024
- DOI for Impact of setup and geometric uncertainties on the robustness of free-breathing photon radiotherapy of small lung tumors
- Download full text (pdf) of Impact of setup and geometric uncertainties on the robustness of free-breathing photon radiotherapy of small lung tumors
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Range shifter contribution to neutron exposure of patients undergoing proton pencil beam scanning
Part of Medical physics (Lancaster), p. 5099-5108, 2024
- DOI for Range shifter contribution to neutron exposure of patients undergoing proton pencil beam scanning
- Download full text (pdf) of Range shifter contribution to neutron exposure of patients undergoing proton pencil beam scanning
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Part of Physica medica (Testo stampato), 2024
- DOI for Patterns of practice of image guided particle therapy for cranio-spinal irradiation: A site specific multi-institutional survey of European Particle Therapy Network
- Download full text (pdf) of Patterns of practice of image guided particle therapy for cranio-spinal irradiation: A site specific multi-institutional survey of European Particle Therapy Network
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Part of Physics and Imaging in Radiation Oncology, 2024
- DOI for Robustness and dosimetric verification of hippocampal-sparing craniospinal pencil beam scanning proton plans for pediatric medulloblastoma
- Download full text (pdf) of Robustness and dosimetric verification of hippocampal-sparing craniospinal pencil beam scanning proton plans for pediatric medulloblastoma
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Part of Neurosurgical review, 2023
- DOI for Proton beam radiation therapy for vestibular schwannomas-tumor control and hearing preservation rates: a systematic review and meta-analysis
- Download full text (pdf) of Proton beam radiation therapy for vestibular schwannomas-tumor control and hearing preservation rates: a systematic review and meta-analysis
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Plan robustness and RBE influence for proton dose painting by numbers for head and neck cancers
Part of Physica medica (Testo stampato), p. 103157, 2023
- DOI for Plan robustness and RBE influence for proton dose painting by numbers for head and neck cancers
- Download full text (pdf) of Plan robustness and RBE influence for proton dose painting by numbers for head and neck cancers
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Part of Neurosurgery, p. 1216-1226, 2023
- DOI for The relevance of biologically effective dose for hearing preservation after stereotactic radiosurgery for vestibular schwannomas: a retrospective longitudinal study
- Download full text (pdf) of The relevance of biologically effective dose for hearing preservation after stereotactic radiosurgery for vestibular schwannomas: a retrospective longitudinal study
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Dosimetric robustness of lung tumor photon radiotherapy evaluated from multiple event CT imaging
Part of Physica medica (Testo stampato), p. 1-10, 2022
- DOI for Dosimetric robustness of lung tumor photon radiotherapy evaluated from multiple event CT imaging
- Download full text (pdf) of Dosimetric robustness of lung tumor photon radiotherapy evaluated from multiple event CT imaging
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Part of Acta Oncologica, p. 206-214, 2022
- DOI for Towards harmonizing clinical linear energy transfer (LET) reporting in proton radiotherapy: A European multi-centric study
- Download full text (pdf) of Towards harmonizing clinical linear energy transfer (LET) reporting in proton radiotherapy: A European multi-centric study
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Part of Frontiers in Oncology, 2022
- DOI for Range-shifter effects on the stray field in proton therapy measured with the variance–covariance method
- Download full text (pdf) of Range-shifter effects on the stray field in proton therapy measured with the variance–covariance method
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Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
Part of Frontiers in Oncology, 2022
- DOI for Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
- Download full text (pdf) of Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
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Part of Frontiers in Oncology, 2022
- DOI for Determining out-of-field doses and second cancer risk from proton therapy in young patients: an overview
- Download full text (pdf) of Determining out-of-field doses and second cancer risk from proton therapy in young patients: an overview
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Editorial: Out-of-field second primary cancer induction: Dosimetry and modelling
Part of Frontiers in Oncology, 2022
- DOI for Editorial: Out-of-field second primary cancer induction: Dosimetry and modelling
- Download full text (pdf) of Editorial: Out-of-field second primary cancer induction: Dosimetry and modelling
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Part of Journal of Magnetic Resonance Imaging, p. 620-622, 2022
- DOI for T1 and T2 mapping for early detection of treatment-related myocardial changes in breast cancer patients
- Download full text (pdf) of T1 and T2 mapping for early detection of treatment-related myocardial changes in breast cancer patients
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Part of Anticancer Research, p. 279-288, 2021
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Part of Advances in Experimental Medicine and Biology, p. 185-190, 2021
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Part of Medical Physics, p. 342-351, 2020
- DOI for Spatial correlation of linear energy transfer and relative biological effectiveness with suspected treatment related toxicities following proton therapy for intracranial tumors
- Download full text (pdf) of Spatial correlation of linear energy transfer and relative biological effectiveness with suspected treatment related toxicities following proton therapy for intracranial tumors
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RBE for proton radiation therapy – a Nordic view in the international perspective
Part of Acta Oncologica, p. 1151-1156, 2020
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Cancer risk after breast proton therapy considering physiological and radiobiological uncertainties
Part of Physica medica (Testo stampato), p. 1-6, 2020
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Mapping the Future of Particle Radiobiology in Europe: The INSPIRE Project
Part of Frontiers in Physics, 2020
- DOI for Mapping the Future of Particle Radiobiology in Europe: The INSPIRE Project
- Download full text (pdf) of Mapping the Future of Particle Radiobiology in Europe: The INSPIRE Project
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Hypoxia induced by vascular damage at high doses could compromise the outcome of radiotherapy
Part of Anticancer Research, p. 2337-2340, 2019
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Part of Medical physics (Lancaster), p. 2512-2521, 2019
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Part of Anticancer Research, p. 2721-2727, 2019
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Part of Radiotherapy and Oncology, p. 4-8, 2018
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Part of Physica medica (Testo stampato), p. 56-61, 2018
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Part of Radiation Protection Dosimetry, p. 261-266, 2018
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Part of Physica medica (Testo stampato), p. 129-136, 2018
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Part of Radiation Protection Dosimetry, p. 338-341, 2018
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Part of Advances in Experimental Medicine and Biology, p. 183-187, 2018
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Mathematical Description of Changes in Tumour Oxygenation from Repeated Functional Imaging
Part of Advances in Experimental Medicine and Biology, p. 195-200, 2018
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Part of Physica medica (Testo stampato), p. 45-51, 2018
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Part of Acta Oncologica, p. 485-490, 2018
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Part of Physica medica (Testo stampato), p. 81-85, 2018
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Part of Acta Oncologica, p. 1428-1436, 2017
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Part of Journal of Instrumentation, 2017
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EPR oximetry of cetuximab-treated head-and-neck tumours in a mouse model
Part of Cell Biochemistry and Biophysics, p. 299-309, 2017
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High brachytherapy doses can counteract hypoxia in cervical cancer - a modelling study
Part of Physics in Medicine and Biology, p. 560-572, 2017
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Quality control in cone-beam computed tomography (CBCT) EFOMP-ESTRO-IAEA protocol (summary report)
Part of Physica medica (Testo stampato), p. 67-72, 2017
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Modelling of a proton spot scanning system using MCNP6
Part of Journal of Physics: Conference Series, 2017
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Part of Acta Oncologica, p. 819-825, 2017
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Part of Physica medica (Testo stampato), p. 88-94, 2017
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Changes in skin microcirculation during radiation therapy for breast cancer
Part of Acta Oncologica, p. 1072-1080, 2017
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Models for the risk of secondary cancers from radiation therapy
Part of Physica medica (Testo stampato), p. 232-238, 2017
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Respiratory gating for proton beam scanning versus photon 3D-CRT for breast cancer radiotherapy
Part of Acta Oncologica, p. 577-583, 2016
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Part of International Journal of Particle Therapy, p. 845-855, 2015
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Part of International Journal of Particle Therapy, p. 845-855, 2015
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Part of Anticancer Research, p. 2841-2848, 2015
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Relative clinical effectiveness of carbon ion radiotherapy: theoretical modelling for H&N tumours
Part of Journal of radiation research, p. 639-645, 2015
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Part of International Journal of Radiation Oncology, Biology, Physics, p. 376-384, 2015
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Predictive Models of Tumour Response to Treatment Using Functional Imaging Techniques
Part of Computational & Mathematical Methods in Medicine, p. 1-2, 2015
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Part of International Federation for Medical and Biological Engineering Proceedings, p. 1675-1678, 2015
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Optimal fractionation in radiotherapy for non-small cell lung cancer – a modelling approach
Part of Acta Oncologica, p. 1592-1598, 2015
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Impact of increasing irradiation time on the treatment of prostate cancers
Part of International Federation for Medical and Biological Engineering Proceedings, p. 490-493, 2015
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Part of British Journal of Radiology, 2015
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Towards Multidimensional Radiotherapy: Key Challenges for Treatment Individualisation
Part of Computational & Mathematical Methods in Medicine, p. 1-8, 2015
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Part of Radiation Oncology, 2014
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Part of Anticancer Research, p. 3563-3568, 2014
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Part of Acta Oncologica, p. 1035-1040, 2014
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Quantitative Hypoxia Imaging for Treatment Planning of Radiotherapy
Part of Advances in Experimental Medicine and Biology, p. 143-148, 2014
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Part of Radiation Protection Dosimetry, p. 357-362, 2014
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Are IMRT treatments in the head and neck region increasing the risk of secondary cancers?
Part of Acta Oncologica, p. 1041-1047, 2014
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Part of Journal of radiation research, p. 902-911, 2014
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To fractionate or not to fractionate? That is the question for the radiosurgery of hypoxic tumors
Part of Journal of Neurosurgery, p. 110-115, 2014
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Part of Anticancer Research, p. 5873-5874, 2014
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Part of Anticancer Research, p. 1009-1011, 2013
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Impact of variable RBE on proton fractionation
Part of Medical physics (Lancaster), 2013
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Part of ISRN Oncology, p. 1-5, 2013
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Part of International Federation for Medical and Biological Engineering Proceedings, p. 1742-1745, 2013
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Part of International Federation for Medical and Biological Engineering Proceedings, p. 1731-1734, 2013
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Modelling Tumour Oxygenation, Reoxygenation and Implications on Treatment Outcome
Part of Computational & Mathematical Methods in Medicine, p. 1-9, 2013
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Part of International Journal of Radiation Oncology, Biology, Physics, p. 554-560, 2012
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Prostate alpha/beta revisited – an analysis of clinical results from 14 168 patients
Part of Acta Oncologica, p. 963-974, 2012
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Part of International Journal of Radiation Oncology, Biology, Physics, p. 738-746, 2011
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Dose prescription and treatment planning based on FMISO-PET hypoxia
Part of Acta Oncologica, p. 222-230, 2011
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Dose prescription and optimisation based on tumour hypoxia
Part of Acta Oncologica, p. 1-12, 2009
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Quantifying tumour hypoxia from PET - a theoretical analysis
Part of Advances in Experimental Medicine and Biology, p. 267-272, 2009
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The relationship between vascular oxygen distribution and tissue oxygenation
Part of Advances in Experimental Medicine and Biology, p. 255-260, 2009
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Part of International Federation for Medical and Biological Engineering Proceedings, p. 237-240, 2009
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Therapy Optimization Based on Non-linear Uptake of PET Tracers versus “Linear Dose Painting”
Part of International Federation for Medical and Biological Engineering Proceedings, p. 221-224, 2009
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Treatment planning optimisation based on imaging tumour proliferation and cell density
Part of Acta Oncologica, p. 1221-1228, 2008
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Vascular oxygen content and the tissue oxygenation-A theoretical analysis
Part of Medical physics (Lancaster), p. 539-545, 2008
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In Response to Dr. Karger et al.
Part of International Journal of Radiation Oncology, Biology, Physics, p. 1614-1615, 2008
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Treatment modelling: The influence of micro-environmental conditions
Part of Acta Oncologica, p. 896-905, 2008
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Part of International Journal of Radiation Oncology, Biology, Physics, p. 867-874, 2008
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Is the α/β Value for Prostate Tumours Low Enough to be Safely Used in Clinical Trials?
Part of Clinical Oncology, p. 289-301, 2007
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Theoretical simulation of tumour oxygenation - practical applications
Part of Advances in Experimental Medicine and Biology, p. 357-362, 2006
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Theoretical simulation of tumour hypoxia measurements
Part of Advances in Experimental Medicine and Biology, p. 369-374, 2006
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Dose-effect models for risk – relationship to cell survival parameters
Part of Acta Oncologica, p. 829-835, 2005
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The use of risk estimation models for the induction of secondary cancers following radiotherapy
Part of Acta Oncologica, p. 339-347, 2005
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Comments on `Comparison of in vitro and in vivo α/β ratios for prostate cancer'
Part of Physics in Medicine and Biology, 2005
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Conversion of polarographic electrode measurements—a computer based approach
Part of Physics in Medicine and Biology, p. 4581-4591, 2005
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The effects of hypoxia on the theoretical modelling of tumour control probability
Part of Acta Oncologica, p. 563-571, 2005
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Part of Physics in Medicine and Biology, p. 4463-4475, 2004
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Theoretical simulation of tumour oxygenation and results from acute and chronic hypoxia
Part of Physics in Medicine and Biology, p. 2829-2842, 2003
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Computer Simulation of Oxygen Microelectrode Measurements in Tissues
Part of Advances in Experimental Medicine and Biology, p. 157-161, 2003
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Part of Physics in Medicine and Biology, p. 387-397, 2003
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The Impact of Tissue Microenvironment on Treatment Simulation
Part of Advances in Experimental Medicine and Biology, p. 63-67, 2003
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Part of Radiotherapy and Oncology, p. 109-118, 2002
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Part of Physiological Measurement, p. 713-725, 2001
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Inducible Repair and Intrinsic Radiosensitivity: A Complex but Predictable Relationship?
Part of Radiation Research, p. 279-288, 2000
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Comments on `Standard effective doses for proliferative tumours'
Part of Physics in Medicine and Biology, 2000
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Inducible Repair and the Two Forms of Tumour Hypoxia - Time for a Paradigm Shift
Part of Acta Oncologica, p. 903-918, 1999
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Part of International Journal of Radiation Oncology, Biology, Physics, p. 1083-1094, 1999
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Liquid ionization chamber measurements of dose distributions in small 6 MV photon beams
Part of Physics in Medicine and Biology, p. 21-36, 1998
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Hyperfractionation as an effective way of overcoming radioresistance
Part of International Journal of Radiation Oncology, Biology, Physics, p. 705-709, 1998
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Part of Advances in Enzyme Regulation, p. 281-299, 1998
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New insights into factors influencing the clinically relevant oxygen enhancement ratio
Part of Radiotherapy and Oncology, p. 269-277, 1998
Articles, review/survey
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Part of Radiotherapy and Oncology, 2026
- DOI for Radiation therapy in adolescents and young adults (AYA): contemporary evidence on utilization, outcomes, late toxicities, and second malignant neoplasms – A comprehensive systematic review and synthesis
- Download full text (pdf) of Radiation therapy in adolescents and young adults (AYA): contemporary evidence on utilization, outcomes, late toxicities, and second malignant neoplasms – A comprehensive systematic review and synthesis
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Part of Radiotherapy and Oncology, p. 177-184, 2021
- DOI for Does uncertainty in variability in relative biological effectiveness affect patient treatment in proton therapy?
- Download full text (pdf) of Does uncertainty in variability in relative biological effectiveness affect patient treatment in proton therapy?
Books
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Radiotherapy and clinical radiobiology of head and neck cancer
CRC Press, 2018
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Optimum overall treatment time in radiation oncology
Medical Physics Publishing, 2015
Chapters in book
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The Six Rs of Head and Neck Cancer Radiotherapy
Part of Contemporary Issues in Head and Neck Cancer Management, p. 35-58, InTech, 2015
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Long-term effects and secondary tumors
Part of Comprehensive Biomedical Physics, Volume 9: Radiation Therapy Physics and Treatment Optimization, p. 223-233, Elsevier, 2014
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Radiobiology of Prostate Cancer
Part of Robotic Radiosurgery, Treating Prostate Cancer and Related Genitourinary Applications, p. 79-101, Springer, 2012
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Influence of acute tumour hypoxia on radiation therapy outcome
Part of AAPM Symposium Proceedings No. 14: Physical, Chemical and Biological Targeting in Radiation Oncology, p. 111-117, Medical Physics Publishing, 2005