Michal Maj
Associate senior lecturer/Assistant Professor at Department of Chemistry - Ångström Laboratory; Physical Chemistry
- E-mail:
- michal.maj@kemi.uu.se
- Visiting address:
- Ångströmlaboratoriet
Lägerhyddsvägen 1
751 20 UPPSALA - Postal address:
- Box 523
751 20 UPPSALA
Short presentation
Research in the Maj group focuses on studying the structure and aggregation kinetics of toxic amyloid intermediates using femtosecond two-dimensional infrared (2D-IR) spectroscopy and cryo-electron microscopy. To increase the structural specificity of 2D-IR, we develop new molecular probes that can be used as IR-active sensors of site-specific structure and dynamics of biomolecules.
For more information see https://www.majgroup.net
Publications
Recent publications
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Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
Part of Journal of Physical Chemistry A, p. 2566-2574, 2026
- DOI for Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
- Download full text (pdf) of Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
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A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
Part of Journal of Physical Chemistry B, p. 3042-3053, 2026
- DOI for A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
- Download full text (pdf) of A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
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Part of RSC Chemical Biology, p. 38-43, 2026
- DOI for High-resolution structure of proIAPP(1–48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs
- Download full text (pdf) of High-resolution structure of proIAPP(1–48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs
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Part of Journal of Chemical Physics, 2026
- DOI for Two-dimensional infrared spectroscopy of solute-solvent complexes from linear-scaling DFT and machine learning
- Download full text (pdf) of Two-dimensional infrared spectroscopy of solute-solvent complexes from linear-scaling DFT and machine learning
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Part of Biochemistry, p. 2583-2595, 2025
- DOI for Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
- Download full text (pdf) of Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
All publications
Articles in journal
-
Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
Part of Journal of Physical Chemistry A, p. 2566-2574, 2026
- DOI for Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
- Download full text (pdf) of Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
-
A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
Part of Journal of Physical Chemistry B, p. 3042-3053, 2026
- DOI for A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
- Download full text (pdf) of A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
-
Part of RSC Chemical Biology, p. 38-43, 2026
- DOI for High-resolution structure of proIAPP(1–48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs
- Download full text (pdf) of High-resolution structure of proIAPP(1–48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs
-
Part of Journal of Chemical Physics, 2026
- DOI for Two-dimensional infrared spectroscopy of solute-solvent complexes from linear-scaling DFT and machine learning
- Download full text (pdf) of Two-dimensional infrared spectroscopy of solute-solvent complexes from linear-scaling DFT and machine learning
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Part of Biochemistry, p. 2583-2595, 2025
- DOI for Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
- Download full text (pdf) of Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
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Part of Journal of Molecular Biology, 2025
- DOI for Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics
- Download full text (pdf) of Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics
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Part of Physical Chemistry, Chemical Physics - PCCP, p. 20279-20287, 2025
- DOI for Detection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery
- Download full text (pdf) of Detection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery
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Part of Journal of the American Chemical Society, p. 45701-45711, 2025
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Part of Communications Chemistry, 2025
- DOI for Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography
- Download full text (pdf) of Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography
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Part of Journal of Chemical Physics, 2025
- DOI for Solvatochromic charge model of isonitrile probes for investigating hydrogen-bond dynamics with 2DIR spectroscopy
- Download full text (pdf) of Solvatochromic charge model of isonitrile probes for investigating hydrogen-bond dynamics with 2DIR spectroscopy
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Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins
Part of Biophysical Journal, p. 718-729, 2024
- DOI for Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins
- Download full text (pdf) of Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins
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Part of Nature Chemistry, p. 624-632, 2024
- DOI for Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
- Download full text (pdf) of Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
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Protein cohabitation: long-term immunoglobulin G storage at room temperature
Part of Journal of materials chemistry. B, p. 5400-5405, 2023
- DOI for Protein cohabitation: long-term immunoglobulin G storage at room temperature
- Download full text (pdf) of Protein cohabitation: long-term immunoglobulin G storage at room temperature
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Part of Journal of Chemical Physics, 2023
- DOI for Ground-state heterogeneity and vibrational energy redistribution in bacterial phytochrome observed with femtosecond 2D IR spectroscopy
- Download full text (pdf) of Ground-state heterogeneity and vibrational energy redistribution in bacterial phytochrome observed with femtosecond 2D IR spectroscopy