Marco Tjakra
PhD student at Department of Pharmacy; Molecular Pharmaceutics
- E-mail:
- marco.tjakra@uu.se
- Visiting address:
- Biomedicinskt Centrum BMC, Husargatan 3
- Postal address:
- Box 580
751 23 UPPSALA
Download contact information for Marco Tjakra at Department of Pharmacy; Molecular Pharmaceutics
- ORCID:
- 0000-0003-2266-4011
Short presentation
https://colotan-etn.eu/
Biography
Marco has studied Biomedical Engineering in Chongqing University, China and graduated with Master of Engineering degree in 2020. His previous research involves signalling pathway in the neurovascular unit and hemodynamic force, as well as toxicology. During bachelor study in Atma Jaya Catholic University of Indonesia, he was investigating antimicrobial compound from essential oil to combat oral biofilm forming bacteria. He was graduated in 2016 as a Bachelor of Science in Biotechnology.
He is always eager to explore and study more regarding different perspectives and aspects of biomedical field, which requires multidisciplinary approach to tackle health problems. Thus leading him into the COLOTAN project.
His project aims to improve the understanding of drug dissolution, diffusion, and absorption from the human colon with a focus on the role of the colonic mucus layer. The obtained results will be used to design drug delivery decision trees for colonic drug delivery as well as improved in silico models for drug absorption from the colon.

Publications
Recent publications
Artificial colonic mucus for studies of the mucus absorption barrier
2025
Part of Molecular Pharmaceutics, p. 4032-4045, 2025
- DOI for Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
- Download full text (pdf) of Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
Part of Journal of Nanobiotechnology, 2025
- DOI for Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus
- Download full text (pdf) of Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus
Development of a canine artificial colonic mucus model for drug diffusion studies
Part of European Journal of Pharmaceutical Sciences, 2024
- DOI for Development of a canine artificial colonic mucus model for drug diffusion studies
- Download full text (pdf) of Development of a canine artificial colonic mucus model for drug diffusion studies
All publications
Articles in journal
Part of Molecular Pharmaceutics, p. 4032-4045, 2025
- DOI for Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
- Download full text (pdf) of Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
Part of Journal of Nanobiotechnology, 2025
- DOI for Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus
- Download full text (pdf) of Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus
Development of a canine artificial colonic mucus model for drug diffusion studies
Part of European Journal of Pharmaceutical Sciences, 2024
- DOI for Development of a canine artificial colonic mucus model for drug diffusion studies
- Download full text (pdf) of Development of a canine artificial colonic mucus model for drug diffusion studies