Daniel Espes
Associate senior lecturer/Assistant Professor at Department of Medical Cell Biology; Research group Daniel Espes
- E-mail:
- daniel.espes@mcb.uu.se
- Visiting address:
- BMC
Husargatan 3
751 23 Uppsala - Postal address:
- Box 571
751 23 UPPSALA
Associate senior lecturer/Assistant Professor at Department of Medical Sciences; Transplantation and regenerative medicine
- Visiting address:
- Akademiska sjukhuset, ingång 40, 5 tr
751 85 Uppsala - Postal address:
- Akademiska sjukhuset, Ingång 40, 5 tr
751 85 UPPSALA

Publications
Recent publications
Part of Biomarker research, p. 67, 2025
Part of Scientific Reports, 2025
- DOI for Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
- Download full text (pdf) of Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
Part of BMJ Open Diabetes Research & Care, 2024
- DOI for Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes
- Download full text (pdf) of Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
Part of EJNMMI Research, 2024
- DOI for PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
- Download full text (pdf) of PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
Part of Diabetologia, p. 199-208, 2024
- DOI for Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
- Download full text (pdf) of Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
All publications
Articles in journal
Part of Biomarker research, p. 67, 2025
Part of Scientific Reports, 2025
- DOI for Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
- Download full text (pdf) of Long-term treatment with gamma-aminobutyric acid (GABA) fails to regain beta-cell function in longstanding type 1 diabetes: results from a randomized trial
Part of BMJ Open Diabetes Research & Care, 2024
- DOI for Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes
- Download full text (pdf) of Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
Part of EJNMMI Research, 2024
- DOI for PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
- Download full text (pdf) of PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
Part of Diabetologia, p. 199-208, 2024
- DOI for Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
- Download full text (pdf) of Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes
Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes
Part of BMJ Open Diabetes Research & Care, 2024
- DOI for Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes
- Download full text (pdf) of Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes
Real-life data of hypoglycemic events in children and adolescents with type 1 diabetes
Part of BMJ Open Diabetes Research & Care, 2023
- DOI for Real-life data of hypoglycemic events in children and adolescents with type 1 diabetes
- Download full text (pdf) of Real-life data of hypoglycemic events in children and adolescents with type 1 diabetes
Classification of Hypoglycemic Events in Type 1 Diabetes Using Machine Learning Algorithms
Part of Diabetes Therapy, p. 953-965, 2023
Part of Diabetologia, p. 1431-1441, 2023
- DOI for Umbilical cord-derived mesenchymal stromal cells preserve endogenous insulin production in type 1 diabetes: a Phase I/II randomised double-blind placebo-controlled trial
- Download full text (pdf) of Umbilical cord-derived mesenchymal stromal cells preserve endogenous insulin production in type 1 diabetes: a Phase I/II randomised double-blind placebo-controlled trial
Part of Biomedicines, 2022
- DOI for Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes
- Download full text (pdf) of Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes
Pregnancy induces pancreatic insulin secretion in women with long-standing type 1 diabetes
Part of BMJ Open Diabetes Research & Care, 2022
- DOI for Pregnancy induces pancreatic insulin secretion in women with long-standing type 1 diabetes
- Download full text (pdf) of Pregnancy induces pancreatic insulin secretion in women with long-standing type 1 diabetes
Irisin-A Pancreatic Islet Hormone
Part of Biomedicines, 2022
- DOI for Irisin-A Pancreatic Islet Hormone
- Download full text (pdf) of Irisin-A Pancreatic Islet Hormone
Part of Journal of Sleep Research, 2022
- DOI for Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial.
- Download full text (pdf) of Acute sleep loss alters circulating fibroblast growth factor 21 levels in humans: A randomised crossover trial.
Part of BMJ Open Diabetes Research & Care, 2022
- DOI for Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis
- Download full text (pdf) of Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis
Part of Peptides, 2021
- DOI for CART decreases islet blood flow, but has no effect on total pancreatic blood flow and glucose tolerance in anesthetized rats
- Download full text (pdf) of CART decreases islet blood flow, but has no effect on total pancreatic blood flow and glucose tolerance in anesthetized rats
Part of International Journal of Molecular Sciences, 2021
- DOI for Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells
- Download full text (pdf) of Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells
GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes
Part of BMJ Open Diabetes Research & Care, 2021
- DOI for GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes
- Download full text (pdf) of GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes
Longitudinal Assessment of 11C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes
Part of Diabetes, p. 966-975, 2021
Part of Obesity, p. 535-542, 2021
- DOI for Changes in Circulating Cytokines and Adipokines After RYGB in Patients with and without Type 2 Diabetes
- Download full text (pdf) of Changes in Circulating Cytokines and Adipokines After RYGB in Patients with and without Type 2 Diabetes
Part of Läkartidningen, 2020
Part of Frontiers in Immunology, 2020
- DOI for Increased Plasma Levels of the Co-stimulatory Proteins CDCP1 and SLAMF1 in Patients With Autoimmune Endocrine Diseases
- Download full text (pdf) of Increased Plasma Levels of the Co-stimulatory Proteins CDCP1 and SLAMF1 in Patients With Autoimmune Endocrine Diseases
Part of Frontiers in Immunology, 2020
- DOI for Mass Cytometry Studies of Patients With Autoimmune Endocrine Diseases Reveal Distinct Disease-Specific Alterations in Immune Cell Subsets
- Download full text (pdf) of Mass Cytometry Studies of Patients With Autoimmune Endocrine Diseases Reveal Distinct Disease-Specific Alterations in Immune Cell Subsets
Part of Endocrine, p. 344-353, 2020
- DOI for Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery
- Download full text (pdf) of Rapid changes in neuroendocrine regulation may contribute to reversal of type 2 diabetes after gastric bypass surgery
Part of BMJ Open Diabetes Research & Care, 2020
- DOI for Better HbA1c during the first years after diagnosis of type 1 diabetes is associated with residual C peptide 10 years later
- Download full text (pdf) of Better HbA1c during the first years after diagnosis of type 1 diabetes is associated with residual C peptide 10 years later
Part of Physiological Reports, 2020
- DOI for Highly blood perfused, highly metabolically active pancreatic islets may be more susceptible for immune attack
- Download full text (pdf) of Highly blood perfused, highly metabolically active pancreatic islets may be more susceptible for immune attack
Unsurpassed Intrahepatic Islet Engraftment: the Quest for New Sites for Beta Cell Replacement
Part of Cell Medicine, 2019
- DOI for Unsurpassed Intrahepatic Islet Engraftment: the Quest for New Sites for Beta Cell Replacement
- Download full text (pdf) of Unsurpassed Intrahepatic Islet Engraftment: the Quest for New Sites for Beta Cell Replacement
Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.
Part of International Journal of Molecular Sciences, 2019
- DOI for Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.
- Download full text (pdf) of Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.
Part of Upsala Journal of Medical Sciences, p. 228-237, 2019
- DOI for Characterization of neural crest-derived stem cells isolated from human bone marrow for improvement of transplanted islet function.
- Download full text (pdf) of Characterization of neural crest-derived stem cells isolated from human bone marrow for improvement of transplanted islet function.
Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI
Part of Acta Diabetologica, p. 1113-1120, 2019
- DOI for Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI
- Download full text (pdf) of Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI
Part of Clinical and Experimental Immunology, p. 64-73, 2019
- DOI for Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes
- Download full text (pdf) of Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes
Part of PLOS ONE, 2018
- DOI for Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes
- Download full text (pdf) of Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes
Part of EBioMedicine, p. 283-294, 2018
- DOI for GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes
- Download full text (pdf) of GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes
Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells
Part of EBioMedicine, 2018
- DOI for Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells
- Download full text (pdf) of Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells
Part of American Journal of Transplantation, p. 1735-1744, 2018
- DOI for Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
- Download full text (pdf) of Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
Part of Journal of Diabetes Research, 2017
- DOI for The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control
- Download full text (pdf) of The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control
Role of regulatory B cells in clinical and experimental type 1 diabetes
Part of Scandinavian Journal of Immunology, p. 349-349, 2017
[(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes
Part of Diabetes, p. 1286-1292, 2017
Increased Interleukin-35 Levels in Patients With Type 1 Diabetes With Remaining C-Peptide
Part of Diabetes Care, p. 1090-1095, 2017
Part of American Journal of Transplantation, p. 3246-3254, 2016
Part of Diabetologia, p. 1968-1972, 2016
Quantification of Beta-Cell Mass in Intramuscular Islet Grafts using Radiolabeled Exendin-4
Part of Transplantation Direct, 2016
- DOI for Quantification of Beta-Cell Mass in Intramuscular Islet Grafts using Radiolabeled Exendin-4
- Download full text (pdf) of Quantification of Beta-Cell Mass in Intramuscular Islet Grafts using Radiolabeled Exendin-4
Part of Transplantation, 2016
Part of Scientific Reports, 2015
- DOI for Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells
- Download full text (pdf) of Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells
Part of Transplantation, p. 2077-2082, 2015
Increased levels of irisin in people with long-standing Type1 diabetes
Part of Diabetic Medicine, p. 1172-1176, 2015
The Cannabinoid Receptor-1 Is an Imaging Biomarker of Brown Adipose Tissue
Part of Journal of Nuclear Medicine, p. 1937-1941, 2015
Part of Journal of labelled compounds & radiopharmaceuticals, 2015
Dosimetry of [Ga-68]Ga-DO3A-VS-Cys(40)-Exendin-4 in rodents, pigs, non-human primates and human
Part of Journal of labelled compounds & radiopharmaceuticals, 2015
Part of Diabetes, p. 3428-3437, 2014
Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes
Part of Diabetologia, p. 50-53, 2014
Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
Part of International Journal of Endocrinology, p. 323407, 2014
- DOI for Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
- Download full text (pdf) of Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
Part of Upsala Journal of Medical Sciences, p. 130-133, 2013
Articles, review/survey
Part of Frontiers in Physiology, 2019
- DOI for Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass
- Download full text (pdf) of Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass
Towards the clinical translation of stem cell therapy for type 1 diabetes
Part of European Journal of Endocrinology, 2017
Pancreatic islet blood flow and its measurement
Part of Upsala Journal of Medical Sciences, p. 81-95, 2016
- DOI for Pancreatic islet blood flow and its measurement
- Download full text (pdf) of Pancreatic islet blood flow and its measurement
Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans
Part of Current Diabetes Reports, 2015
Striated Muscle as Implantation Site for Transplanted Pancreatic Islets
Part of Journal of Transplantation, p. 352043, 2011
Comprehensive doctoral thesis
2016
Conference papers
Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
Part of Typ1 ?Typ x Språk: - Engelska Svenska Norska Arabiska Bokmål Bulgariska Danska Engelska Esperanto Estniska Finska Franska Färöiska Grönländska (Kalaallit oqaasi) Hebreiska Hindi Indonesiska Iriska Isländska Italienska Japanska Katalanska Kinesiska Koreanska Kroatiska Kurdiska Latin Lettiska Litauiska Madurese Makedonska Mongoliskt språk Nederländska Norska Nygrekiska (1453-) Nynorsk Odefinierat språk Persiska Polska Portugisiska Rumänska Ryska Samiskt språk Sanskrit Serbiska Slovakiska Slovenska Spanska Svenska Tjeckiska Turkiska Tyska Ukrainska Ungerska Urdu Vietnamesiska, 2014