Angelica Fasching

Adenosine reuptake inhibition reduces diabetes-induced glomerular hyperfiltration via the adenosine A2_a receptor

Persson, Patrik; Fasching, Angelica; Pihl, Liselotte; Palm, Fredrik

Part of American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2023

• DOI for Adenosine reuptake inhibition reduces diabetes-induced glomerular hyperfiltration via the adenosine A2_a receptor

Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

Burmakin, Mikhail; Fasching, Angelica; Kobayashi, Hanako; Urrutia, Andrés A. et al.

Part of Acta Physiologica, 2021

• DOI for Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation
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Determinants of renal oxygen metabolism during low Na⁺ diet: effect of angiotensin II AT₁ and aldosterone receptor blockade

Patinha, Daniela; Carvalho, Carla; Persson, Patrik; Pihl, Liselotte et al.

Part of Journal of Physiology, p. 5573-5587, 2020

• DOI for Determinants of renal oxygen metabolism during low Na⁺ diet: effect of angiotensin II AT₁ and aldosterone receptor blockade
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Acute intrarenal angiotensin (1-7) infusion decreases diabetes-induced glomerular hyperfiltration but increases kidney oxygen consumption in the rat

Persson, Patrik; Fasching, Angelica; Palm, Fredrik

Part of Acta Physiologica, 2019

• DOI for Acute intrarenal angiotensin (1-7) infusion decreases diabetes-induced glomerular hyperfiltration but increases kidney oxygen consumption in the rat

Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability

Sivertsson, Ebba; Friederich Persson, Malou; Öberg, Carl M.; Fasching, Angelica et al.

Part of American Journal of Physiology - Renal Physiology, 2018

• DOI for Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability

Adenosine reuptake inhibition reduces diabetes-induced glomerular hyperfiltration via the adenosine A2_a receptor

Persson, Patrik; Fasching, Angelica; Pihl, Liselotte; Palm, Fredrik

Part of American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2023

• DOI for Adenosine reuptake inhibition reduces diabetes-induced glomerular hyperfiltration via the adenosine A2_a receptor

Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

Burmakin, Mikhail; Fasching, Angelica; Kobayashi, Hanako; Urrutia, Andrés A. et al.

Part of Acta Physiologica, 2021

• DOI for Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation
• Download full text (pdf) of Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

Determinants of renal oxygen metabolism during low Na⁺ diet: effect of angiotensin II AT₁ and aldosterone receptor blockade

Patinha, Daniela; Carvalho, Carla; Persson, Patrik; Pihl, Liselotte et al.

Part of Journal of Physiology, p. 5573-5587, 2020

• DOI for Determinants of renal oxygen metabolism during low Na⁺ diet: effect of angiotensin II AT₁ and aldosterone receptor blockade
• Download full text (pdf) of Determinants of renal oxygen metabolism during low Na⁺ diet: effect of angiotensin II AT₁ and aldosterone receptor blockade

Acute intrarenal angiotensin (1-7) infusion decreases diabetes-induced glomerular hyperfiltration but increases kidney oxygen consumption in the rat

Persson, Patrik; Fasching, Angelica; Palm, Fredrik

Part of Acta Physiologica, 2019

• DOI for Acute intrarenal angiotensin (1-7) infusion decreases diabetes-induced glomerular hyperfiltration but increases kidney oxygen consumption in the rat

Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability

Sivertsson, Ebba; Friederich Persson, Malou; Öberg, Carl M.; Fasching, Angelica et al.

Part of American Journal of Physiology - Renal Physiology, 2018

• DOI for Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability

Intrarenal activation of endothelin type B receptors improves kidney oxygenation in type 1 diabetic rats

Franzén, Stephanie; Pihl, Liselotte; Fasching, Angelica; Palm, Fredrik

Part of American Journal of Physiology - Renal Physiology, 2018

• DOI for Intrarenal activation of endothelin type B receptors improves kidney oxygenation in type 1 diabetic rats

Cellular transport of L-Arginine determines renal medullary blood flow in control rats, but not in diabetic rats despite enhanced cellular uptake capacity

Persson, Patrik; Fasching, Angelica; Teerlink, Tom; Hansell, Peter et al.

Part of American Journal of Physiology - Renal Physiology, 2017

• DOI for Cellular transport of L-Arginine determines renal medullary blood flow in control rats, but not in diabetic rats despite enhanced cellular uptake capacity

Iodinated contrast media inhibit oxygen consumption in freshly isolated proximal tubular cells from elderly humans and diabetic rats: Influence of nitric oxide.

Liss, Per; Hansell, Peter; Fasching, Angelica; Palm, Fredrik

Part of Upsala Journal of Medical Sciences, p. 12-16, 2016

• DOI for Iodinated contrast media inhibit oxygen consumption in freshly isolated proximal tubular cells from elderly humans and diabetic rats: Influence of nitric oxide.
• Download full text (pdf) of Iodinated contrast media inhibit oxygen consumption in freshly isolated proximal tubular cells from elderly humans and diabetic rats: Influence of nitric oxide.

Acute SGLT inhibition normalizes O-2 tension in the renal cortex but causes hypoxia in the renal medulla in anaesthetized control and diabetic rats

O'Neill, Julie; Fasching, Angelica; Pihl, Liselotte; Patinha, Daniela et al.

Part of American Journal of Physiology - Renal Physiology, 2015

• DOI for Acute SGLT inhibition normalizes O-2 tension in the renal cortex but causes hypoxia in the renal medulla in anaesthetized control and diabetic rats

Adenosine A2 a receptor stimulation prevents proteinuria in diabetic rats by promoting an anti-inflammatory phenotype without affecting oxidative stress

Persson, Patrik; Friederich-Persson, Malou; Fasching, Angelica; Hansell, Peter et al.

Part of Acta Physiologica, p. 311-318, 2015

• DOI for Adenosine A2 a receptor stimulation prevents proteinuria in diabetic rats by promoting an anti-inflammatory phenotype without affecting oxidative stress

Activation of Hypoxia-Inducible Factors Prevents Diabetic Nephropathy

Nordquist, Lina; Friederich-Persson, Malou; Fasching, Angelica; Liss, Per et al.

Part of Journal of the American Society of Nephrology, p. 328-338, 2015

• DOI for Activation of Hypoxia-Inducible Factors Prevents Diabetic Nephropathy

L-citrulline, but not L-arginine, prevents diabetes-induced glomerular hyperfiltration and proteinuria

Persson, Patrik; Fasching, Angelica; Teerlink, Tom; Hansell, Peter et al.

Part of The FASEB Journal, 2014

Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes

Franzen, Stephanie; Friederich-Persson, Malou; Fasching, Angelica; Hansell, Peter et al.

Part of American Journal of Physiology-Renal Physiology, 2014

• DOI for Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes

L-Citrulline, But Not L-Arginine, Prevents Diabetes Mellitus–Induced Glomerular Hyperfiltration and Proteinuria in Rat

Persson, Patrik; Fasching, Angelica; Teerlink, Tom; Hansell, Peter et al.

Part of Hypertension, p. 323-329, 2014

• DOI for L-Citrulline, But Not L-Arginine, Prevents Diabetes Mellitus–Induced Glomerular Hyperfiltration and Proteinuria in Rat

Renal hypoxia due to increased oxygen metabolism is an independent pathway to nephropathy

Friederich-Persson, Malou; Persson, Patrik; Fasching, Angelica; Hansell, Peter et al.

Part of The FASEB Journal, 2014

Increased kidney metabolismas a pathway to kidney tissue hypoxia and damage: effects of triiodothyronine and dinitrophenol in normoglycemic rats

Friederich-Persson, Malou; Persson, Patrik; Fasching, Angelica; Hansell, Peter et al.

Part of Advances in Experimental Medicine and Biology, p. 9-14, 2013

• DOI for Increased kidney metabolismas a pathway to kidney tissue hypoxia and damage: effects of triiodothyronine and dinitrophenol in normoglycemic rats

Hypoxia in the diabetic kidney is independent of advanced glycation end-products

Nordquist, Lina; Liss, Per; Fasching, Angelica; Hansell, Peter et al.

Part of Advances in Experimental Medicine and Biology, p. 185-193, 2013

• DOI for Hypoxia in the diabetic kidney is independent of advanced glycation end-products

Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors

Patinha, Daniela; Fasching, Angelica; Pinho, Dora; Albino-Teixeira, Antonio et al.

Part of American Journal of Physiology - Renal Physiology, 2013

• DOI for Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors

Insulin induces the correlation between renal blood flow and glomerular filtration rate in diabetes: implications for mechanisms causing hyperfiltration

Pihl, Liselotte; Persson, Patrik; Fasching, Angelica; Hansell, Peter et al.

Part of American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2012

• DOI for Insulin induces the correlation between renal blood flow and glomerular filtration rate in diabetes: implications for mechanisms causing hyperfiltration

Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney

Palm, Fredrik; Fasching, Angelica; Hansell, Peter; Källskog, Örjan

Part of American Journal of Physiology - Renal Physiology, 2010

• DOI for Nitric oxide originating from NOS1 controls oxygen utilization and electrolyte transport efficiency in the diabetic kidney

Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress

Palm, Fredrik; Nangaku, Masaomi; Fasching, Angelica; Tanaka, Tetsuhiro et al.

Part of American Journal of Physiology - Renal Physiology, 2010

• DOI for Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress

The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney

Edlund, Jenny; Fasching, Angelica; Liss, Per; Hansell, Peter et al.

Part of Diabetes/Metabolism Research Reviews, p. 349-356, 2010

• DOI for The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney

Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption

Nordquist, Lina; Brown, Russell; Fasching, Angelica; Sjöquist, Mats et al.

Part of American Journal of Physiology - Renal Physiology, 2009

• DOI for Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption

Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging

Edlund, Jenny; Hansell, Peter; Fasching, Angelica; Liss, Per et al.

Part of Advances in Experimental Medicine and Biology, p. 199-204, 2009

• DOI for Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging

Iodinated contrast media decrease renomedullary blood flow. A possible cause of contrast media-induced nephropathy

Liss, Per; Hansell, Peter; Carlsson, Per-Ola; Fasching, Angelica et al.

Part of Advances in Experimental Medicine and Biology, p. 213-218, 2009

• DOI for Iodinated contrast media decrease renomedullary blood flow. A possible cause of contrast media-induced nephropathy

Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells

Friederich, Malou; Fasching, Angelica; Hansell, Peter; Nordquist, Lina et al.

Part of Biochimica et Biophysica Acta, p. 935-940, 2008

• DOI for Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells

Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism

Palm, Fredrik; Carlsson, Per-Ola; Fasching, Angelica; Hansell, Peter et al.

Part of Advances in Experimental Medicine and Biology, p. 161-166, 2006

Effects of the contrast medium iopromide on renal hemodynamics and oxygen tension in the diabetic rat kidney

Palm, Fredrik; Carlsson, Per-Ola; Fasching, Angelica; Hellberg, Olof et al.

Part of Advances in Experimental Medicine and Biology, p. 653-659, 2003

Changing dopaminergic activity through different pathways: consequences for renal sodium excretion, regional blood flow and oxygen tension in the rat.

Odlind, Cecilia; Fasching, Angelica; Liss, Per; Palm, Fredrik et al.

Part of Acta Physiol Scand, p. 219-26, 2001

Uncoupling protein-2 in diabetic kidneys: increased protein expression correlates to increased non-transport related oxygen consumption

Friederich, Malou; Olerud, Johan; Fasching, Angelica; Liss, Per et al.

Part of Oxygen Transport to Tissue XXIX, p. 37-43, Springer Berlin/Heidelberg, 2008

• DOI for Uncoupling protein-2 in diabetic kidneys: increased protein expression correlates to increased non-transport related oxygen consumption

Tissue Specific Binding of Radiolabelled C-Peptide in Healthy and Diabetic Rats

Nensén, Oskar; Lindfors, Lina; Fasching, Angelica; Kihlberg, Jan et al.