Olle Korsgren

Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue

Yngve, Erik; Ingvast, Sofie; Korsgren, Olle; Yu, Di

Part of Upsala Journal of Medical Sciences, 2025

• DOI for Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue

DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Part of Scientific Reports, 2025

• DOI for DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Puuvuori, Emmi; Shen, Yunbing; Hulsart-Billström, Gry; Mitran, Bogdan et al.

Part of Journal of Nuclear Medicine, p. 294-299, 2024

• DOI for Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule

Wegrzyniak, Olivia; Lechi, Francesco; Mitran, Bogdan; Cheung, Pierre et al.

Part of iScience, 2024

• DOI for Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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Outcome after total pancreatectomy with islet autotransplantation: A European single-center study

Froberg, Klara; Halimi, Asif; Vujasinovic, Miroslav; Caballero-Corbalán, José et al.

Part of Scandinavian Journal of Surgery, p. 80-87, 2024

• DOI for Outcome after total pancreatectomy with islet autotransplantation: A European single-center study
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Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue

Yngve, Erik; Ingvast, Sofie; Korsgren, Olle; Yu, Di

Part of Upsala Journal of Medical Sciences, 2025

• DOI for Evaluation of drug delivery vehicles for improved transduction of oncolytic adenoviruses in solid tumor tissue

DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Part of Scientific Reports, 2025

• DOI for DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Puuvuori, Emmi; Shen, Yunbing; Hulsart-Billström, Gry; Mitran, Bogdan et al.

Part of Journal of Nuclear Medicine, p. 294-299, 2024

• DOI for Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis

Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule

Wegrzyniak, Olivia; Lechi, Francesco; Mitran, Bogdan; Cheung, Pierre et al.

Part of iScience, 2024

• DOI for Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule
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Outcome after total pancreatectomy with islet autotransplantation: A European single-center study

Froberg, Klara; Halimi, Asif; Vujasinovic, Miroslav; Caballero-Corbalán, José et al.

Part of Scandinavian Journal of Surgery, p. 80-87, 2024

• DOI for Outcome after total pancreatectomy with islet autotransplantation: A European single-center study
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Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data

Teixeira, Pedro F.; Battelino, Tadej; Carlsson, Anneli; Gudbjornsdottir, Soffia et al.

Part of Diabetologia, p. 985-994, 2024

• DOI for Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data
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Reduced expression of central innate defense molecules in pancreatic biopsies from subjects with Type 1 diabetes

Tegehall, Angie; Ingvast, Sofie; Krogvold, Lars; Dahl-Jørgensen, Knut et al.

Part of Acta Diabetologica, 2024

• DOI for Reduced expression of central innate defense molecules in pancreatic biopsies from subjects with Type 1 diabetes
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Illuminating the complete ߟ-cell mass of the human pancreas: signifying a new view on the islets of Langerhans

Lehrstrand, Joakim; Davies, Wayne I. L.; Hahn, Max; Korsgren, Olle et al.

Part of Nature Communications, 2024

• DOI for Illuminating the complete ߟ-cell mass of the human pancreas: signifying a new view on the islets of Langerhans
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Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Wegrzyniak, Olivia; Zhang, Bo; Rokka, Johanna; Rosestedt, Maria et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2023

• DOI for Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β
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[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Part of Pharmaceutics, 2023

• DOI for [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44
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Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Part of EJNMMI Research, p. 107, 2023

• DOI for Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.
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PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Part of Journal of Nuclear Medicine, p. 423-429, 2023

• DOI for PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angie; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022

• DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats
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PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

Puuvuori, Emmi; Liggieri, Francesco; Velikyan, Irina; Chiodaroli, Elena et al.

Part of EJNMMI Research, 2022

• DOI for PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE
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Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Granlund, Louise; Hedin, Anders; Korsgren, Olle; Skog, Oskar et al.

Part of PLOS ONE, 2022

• DOI for Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
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Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

Diamanti, Klev; Cavalli, Marco; Pereira, Maria J.; Pan, Gang et al.

Part of Cell Reports Medicine, 2022

• DOI for Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Golec, Ewelina; Ekstrom, Alexander; Noga, Maciej; Omar-Hmeadi, Muhmmad et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI for Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
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Islet Gene View-a tool to facilitate islet research

Asplund, Olof; Storm, Petter; Chandra, Vikash; Hatem, Gad et al.

Part of Life Science Alliance, 2022

• DOI for Islet Gene View-a tool to facilitate islet research
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Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Part of Scientific Reports, 2021

• DOI for Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
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US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

Piemonti, Lorenzo; Andres, Axel; Casey, John; de Koning, Eelco et al.

Part of Transplant International, p. 1182-1186, 2021

• DOI for US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Part of Biomedicines, 2021

• DOI for PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs
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Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up

Saellstrom, Sara; Sadeghi, Arian; Eriksson, Emma; Segall, Thomas et al.

Part of Frontiers in Veterinary Science, 2021

• DOI for Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up
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Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation

Bergström, Marcus; Yao, Ming; Müller, Malin; Korsgren, Olle et al.

Part of Transplant International, p. 2816-2823, 2021

• DOI for Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation
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Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Part of Circulation Research, p. 1694-1707, 2021

• DOI for Perivascular macrophages regulate blood flow following tissue damage

Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Part of BMJ Open Diabetes Research & Care, 2021

• DOI for Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes
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3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas

Hahn, Max; Nord, Christoffer; Eriksson, Maria; Morini, Federico et al.

Part of Communications Biology, 2021

• DOI for 3D imaging of human organs with micrometer resolution-applied to the endocrine pancreas
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Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Part of Nuclear Medicine and Biology, p. 54-62, 2021

• DOI for Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1
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Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes

Markmann, James F.; Rickels, Michael R.; Eggerman, Thomas L.; Bridges, Nancy D. et al.

Part of American Journal of Transplantation, p. 1477-1492, 2021

• DOI for Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes

Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Per-Anton; Hedin, Anders; Granlund, Louise et al.

Part of PLOS ONE, 2021

• DOI for Transcriptional analysis of islets of Langerhans from organ donors of different ages

Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Part of Diabetologia, p. 2491-2501, 2021

• DOI for Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
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Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Part of Diabetes, p. 966-975, 2021

• DOI for Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

Jonsson, Alexander; Hedin, Anders; Müller, Malin; Skog, Oskar et al.

Part of Scientific Reports, 2020

• DOI for Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism
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Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence

Hahn, Max; Nord, Christoffer; Franklin, Oskar; Alanentalo, Tomas et al.

Part of Scientific Reports, 2020

• DOI for Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence
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Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

Neiman, Daniel; Gillis, David; Piyanzin, Sheina; Cohen, Daniel et al.

Part of JCI Insight, 2020

• DOI for Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

The role of vitamin D in the aetiology of type 1 diabetes

Korsgren, Olle

Part of Diabetologia, p. 1279-1280, 2020

• DOI for The role of vitamin D in the aetiology of type 1 diabetes

Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function

Abadpour, Shadab; Tyrberg, Bjorn; Schive, Simen W.; Huldt, Charlotte Wennberg et al.

Part of Diabetologia, p. 1355-1367, 2020

• DOI for Inhibition of the prostaglandin D₂-GPR44/DP2 axis improves human islet survival and function
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Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study

Nano, Rita; Kerr-Conte, Julie A.; Scholz, Hanne; Engelse, Marten et al.

Part of Transplantation, p. 190-196, 2020

• DOI for Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study

Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes

Maffi, Paola; Lundgren, Torbjorn; Tufveson, Gunnar; Rafael, Ehab et al.

Part of Diabetes Care, p. 710-718, 2020

• DOI for Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes

On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Skog, Oskar; Korsgren, Olle

Part of Acta Diabetologica, p. 503-511, 2020

• DOI for On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes
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Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Jonsson, Alexander; Yngve, Erik; Karlsson, Marie; Ingvast, Sofie et al.

Part of Journal of Histochemistry and Cytochemistry, p. 99-105, 2019

• DOI for Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Part of Nuclear Medicine and Biology, p. 1-10, 2019

• DOI for Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass
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Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells

Bergström, Marcus; Müller, Malin; Karlsson, Marie; Scholz, Hanne et al.

Part of Cell Transplantation, p. 1603-1613, 2019

• DOI for Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells
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Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Seiron, Peter; Wiberg, Anna; Kuric, Enida; Krogvold, Lars et al.

Part of The journal of pathology. Clinical research, p. 248-255, 2019

• DOI for Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
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Teplizumab in Relatives at Risk for Type 1 Diabetes

Korsgren, Olle; Skog, Oskar; Ludvigsson, Johnny

Part of New England Journal of Medicine, p. 1879-1880, 2019

• DOI for Teplizumab in Relatives at Risk for Type 1 Diabetes

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, Olle; Skyler, Jay S; Skog, Oskar; Sundberg, Frida et al.

Part of Nature Reviews Endocrinology, p. 623-624, 2019

• DOI for Imagining a better future for all people with type 1 diabetes mellitus

Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation

von Zur-Mühlen, Bengt; Lundgren, Torbjorn; Bayman, Levent; Berne, Christian et al.

Part of Transplantation, p. 630-637, 2019

• DOI for Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation
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Proton MR spectroscopy of human pancreas allografts

Weis, Jan; Ahlström, Håkan; Korsgren, Olle

Part of Magnetic Resonance Materials in Physics, Biology and Medicine, p. 511-517, 2019

• DOI for Proton MR spectroscopy of human pancreas allografts
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A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Helker, Christian S M; Mullapudi, Sri-Teja; Mueller, Laura M; Preussner, Jens et al.

Part of Development, 2019

• DOI for A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Islets for Research: Nothing Is Perfect, but We Can Do Better

Nano, Rita; Kerr-Conte, Julie A.; Bosco, Domenico; Karlsson, Marie et al.

Part of Diabetes, p. 1541-1543, 2019

• DOI for Islets for Research: Nothing Is Perfect, but We Can Do Better

Characterization of host defense molecules in the human pancreas

Stenwall, Anton; Ingvast, Sofie; Skog, Oskar; Korsgren, Olle

Part of Islets, p. 89-101, 2019

• DOI for Characterization of host defense molecules in the human pancreas
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Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Skog, Oskar; Klingel, Karin; Roivainen, Merja; Korsgren, Olle

Part of Diabetologia, p. 1097-1099, 2019

• DOI for Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation

Brandhorst, Heide; Johnson, Paul R.; Moench, Johanna; Kurfuerst, Manfred et al.

Part of Cell Transplantation, p. 176-184, 2019

• DOI for Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation
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Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

Lundberg, Marcus; Stenwall, Per-Anton; Tegehall, Angie; Korsgren, Olle et al.

Part of Islets, p. 69-79, 2018

• DOI for Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Fuchs, Anke; Gliwiński, Mateusz; Grageda, Nathali; Spiering, Rachel et al.

Part of Frontiers in Immunology, 2018

• DOI for Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.
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The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan, Mahabuba; Johnström, Peter; Selvaraju, Ramkumar; Svedberg, Marie et al.

Part of EJNMMI Research, 2018

• DOI for The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.
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Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

Carlsson, Per-Ola; Espes, Daniel; Sedigh, Amir; Rotem, Avi et al.

Part of American Journal of Transplantation, p. 1735-1744, 2018

• DOI for Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
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Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Eriksson, Olof; Korsgren, Olle; Selvaraju, Ram Kumar; Mollaret, Marjorie et al.

Part of Acta Diabetologica, p. 49-57, 2018

• DOI for Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4
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Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Gotthardt, Martin; Eizirik, Decio L.; Aanstoot, Henk-Jan; Korsgren, Olle et al.

Part of Diabetologia, p. 2516-2519, 2018

• DOI for Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Part of European Journal of Clinical Investigation, p. 44-45, 2018

• DOI for Perivascular macrophages regulate blood flow following tissue damage

No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Kuric, Enida; Krogvold, Lars; Hanssen, Kristian F.; Dahl-Jorgensen, Knut et al.

Part of American Journal of Pathology, p. 1744-1748, 2018

• DOI for No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas

Eich, Torsten; Ståhle, Magnus U.; Gustafsson, Bengt; Horneland, Rune et al.

Part of Cell Transplantation, p. 1031-1038, 2018

• DOI for Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas
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Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT

Abadpour, Shadab; Halvorsen, Bente; Sahraoui, Afaf; Korsgren, Olle et al.

Part of Journal of Molecular Endocrinology, p. 171-183, 2018

• DOI for Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT

Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Skog, Oskar; Korsgren, Olle

Part of Diabetes, obesity and metabolism, p. 775-785, 2018

• DOI for Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

In Vivo Visualization of beta-Cells by Targeting of GPR44

Eriksson, Olof; Johnström, Peter; Cselenyi, Zsolt; Jahan, Mahabuba et al.

Part of Diabetes, p. 182-192, 2018

• DOI for In Vivo Visualization of beta-Cells by Targeting of GPR44

Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

Schive, Simen W.; Mirlashari, Mohammad Reza; Hasvold, Grete; Wang, Mengyu et al.

Part of Cell Medicine, p. 103-116, 2017

• DOI for Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo

Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

Abadpour, Shadab; Göpel, Sven O.; Schive, Simen W.; Korsgren, Olle et al.

Part of Scientific Reports, 2017

• DOI for Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis
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Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity

Brandhorst, Heide; Johnson, Paul R. V.; Korsgren, Olle; Brandhorst, Daniel

Part of Cell Transplantation, p. 1733-1741, 2017

• DOI for Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity
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Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Kuric, Enida; Seiron, Peter; Krogvold, Lars; Edwin, Bjørn et al.

Part of American Journal of Pathology, p. 581-588, 2017

• DOI for Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Insulitis in human diabetes: a histological evaluation of donor pancreases

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 346-353, 2017

• DOI for Insulitis in human diabetes: a histological evaluation of donor pancreases
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Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Skog, Oskar; Korsgren, Olle

Part of Diabetes, 2017

• DOI for Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

[(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Martinell, Mats et al.

Part of Diabetes, p. 1286-1292, 2017

• DOI for [(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Pre-transplantation ³¹P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts: A feasibility study

Carlbom, Lina; Weis, Jan; Johansson, Lars; Korsgren, Olle et al.

Part of Magnetic Resonance Imaging, p. 98-102, 2017

• DOI for Pre-transplantation ³¹P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts: A feasibility study

Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation

Brandhorst, Daniel; Parnaud, Geraldine; Friberg, Andrew; Lavallard, Vanessa et al.

Part of Cell Transplantation, p. 1688-1693, 2017

• DOI for Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation
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Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report

Horneland, R.; Guvag, S.; Korsgren, Olle; Aandahl, E.

Part of American Journal of Transplantation, p. 693-694, 2017

• DOI for Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report

Cost and clinical outcome of islet transplantation in Norway 2010-2015

Schive, Simen W.; Foss, Aksel; Sahraoui, Afaf; Kloster-Jensen, Kristine et al.

Part of Clinical Transplantation, 2017

• DOI for Cost and clinical outcome of islet transplantation in Norway 2010-2015

Characterization of resident lymphocytes in human pancreatic islets

Radenkovic, M; Uvebrant, K; Skog, Oskar; Sarmiento, L et al.

Part of Clinical and Experimental Immunology, p. 418-427, 2017

• DOI for Characterization of resident lymphocytes in human pancreatic islets

Islet Encapsulation: Physiological Possibilities and Limitations

Korsgren, Olle

Part of Diabetes, p. 1748-1754, 2017

• DOI for Islet Encapsulation: Physiological Possibilities and Limitations

Direct Substrate Delivery into Mitochondrial-Fission Deficient Pancreatic Islets Rescues Insulin Secretion

Kabra, Uma D; Pfuhlmann, Katrin; Migliorini, Adriana; Keipert, Susanne et al.

Part of Diabetes, p. 1247-1257, 2017

• DOI for Direct Substrate Delivery into Mitochondrial-Fission Deficient Pancreatic Islets Rescues Insulin Secretion

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 756-757, 2017

• DOI for Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

Rydén, Anneli; Nyman, Gorel; Nalin, Lovisa; Andreasson, Susanne et al.

Part of Nuclear Medicine and Biology, p. 397-402, 2016

• DOI for Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs

Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation

Ståhle, Magnus; Foss, Aksel; Gustafsson, Bengt; Lempinen, Marko et al.

Part of Cell Transplantation, p. 2269-2276, 2016

• DOI for Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation
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Positron Emission Tomography to assess the outcome of intraportal islet transplantation

Eriksson, Olof; Selvaraju, Ramkumar; Eich, Torsten; Willny, Mariam et al.

Part of Diabetes, p. 2482-2489, 2016

• DOI for Positron Emission Tomography to assess the outcome of intraportal islet transplantation

GPR44 is a pancreatic protein restricted to the human beta cell

Hellström-Lindahl, Ewa; Danielsson, Angelika; Pontén, Fredrik; Czernichow, Paul et al.

Part of Acta Diabetologica, p. 413-421, 2016

• DOI for GPR44 is a pancreatic protein restricted to the human beta cell

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

Domsgen, Erna; Lind, Katharina; Kong, Lingjia; Huhn, Michael H. et al.

Part of Scientific Reports, 2016

• DOI for An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets
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Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation

Brandhorst, Heide; Kurfuerst, Manfred; Johnson, Paul R.; Korsgren, Olle et al.

Part of TRANSPLANTATION DIRECT, 2016

• DOI for Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation
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Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Hårdstedt, Maria; Lindblom, Susanne; Karlsson-Para, Alex; Nilsson, Bo et al.

Part of Cell Transplantation, p. 503-515, 2016

• DOI for Characterization of innate immunity in an extended whole blood model of human islet allotransplantation

Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Eriksson, Olof et al.

Part of Diabetologia, p. 1968-1972, 2016

• DOI for Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes

Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

Davies, Lindsay C.; Alm, Jessica J.; Heldring, Nina; Moll, Guido et al.

Part of Stem Cells Translational Medicine, p. 1485-1495, 2016

• DOI for Type 1 Diabetes Mellitus Donor Mesenchymal. Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro

Identification of proliferative and mature beta-cells in the islets of Langerhans

Bader, Erik; Migliorini, Adriana; Gegg, Moritz; Moruzzi, Noah et al.

Part of Nature, p. 430-+, 2016

• DOI for Identification of proliferative and mature beta-cells in the islets of Langerhans

Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement

Bartlett, Stephen T.; Markmann, James F.; Johnson, Paul; Korsgren, Olle et al.

Part of Transplantation, 2016

• DOI for Report from IPITA-TTS Opinion Leaders Meeting on the Future of beta-Cell Replacement
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Glucose Effectiveness: The Mouse Trap in the Development of Novel beta-Cell Replacement Therapies

Korsgren, Erik; Korsgren, Olle

Part of Transplantation, p. 111-115, 2016

• DOI for Glucose Effectiveness: The Mouse Trap in the Development of Novel beta-Cell Replacement Therapies

Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

von Herrath, M. G.; Korsgren, Olle; Atkinson, M. A.

Part of Clinical and Experimental Immunology, p. 1-7, 2016

• DOI for Factors impeding the discovery of an intervention-based treatment for type 1 diabetes

An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas

Korsgren, Erik; Korsgren, Olle

Part of Diabetes, p. 1004-1008, 2016

• DOI for An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Krogvold, Lars; Wiberg, Anna; Edwin, Bjørn; Buanes, Trond et al.

Part of Diabetologia, p. 492-501, 2016

• DOI for Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids

Kloster-Jensen, Kristine; Sahraoui, Afaf; Vethe, Nils Tore; Korsgren, Olle et al.

Part of Journal of Diabetes Research, 2016

• DOI for Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids
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First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial

Cooper, David K. C.; Bottino, Rita; Gianello, Pierre; Graham, Melanie et al.

Part of Xenotransplantation, p. 46-52, 2016

• DOI for First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

Ricordi, Camillo; Goldstein, Julia S.; Balamurugan, A. N.; Szot, Gregory L. et al.

Part of Diabetes, p. 3418-3428, 2016

• DOI for National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Hering, Bernhard J.; Clarke, William R.; Bridges, Nancy D.; Eggerman, Thomas L. et al.

Part of Diabetes Care, p. 1230-1240, 2016

• DOI for Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation

Ståhle, Magnus; Foss, Aksel; Gustafsson, Bengt; Lempinen, Marko et al.

Part of Transplantation direct, p. 1-6, 2015

• DOI for Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation

Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Part of Cell Transplantation, p. 263-276, 2015

• DOI for Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Skog, Oskar; Korsgren, Stella; Wiberg, Anna; Danielsson, Angelika et al.

Part of American Journal of Pathology, p. 129-138, 2015

• DOI for Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

A novel model for studies of blood-mediated long-term responses to cellular transplants

Hårdstedt, Maria; Lindblom, Susanne; Hong, Jaan; Nilsson, Bo et al.

Part of Upsala Journal of Medical Sciences, p. 28-39, 2015

• DOI for A novel model for studies of blood-mediated long-term responses to cellular transplants

The Effects of Exendin-4 Treatment on Graft Failure: An Animal Study Using a Novel Re-Vascularized Minimal Human Islet Transplant Model

Sahraoui, Afaf; Winzell, Maria Soerhede; Gorman, Tracy; Smith, Dave M. et al.

Part of PLOS ONE, 2015

• DOI for The Effects of Exendin-4 Treatment on Graft Failure: An Animal Study Using a Novel Re-Vascularized Minimal Human Islet Transplant Model
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Human islet distribution programme for basic research: activity over the last 5 years

Nano, Rita; Bosco, Domenico; Kerr-Conte, Julie A.; Karlsson, Marie et al.

Part of Diabetologia, p. 1138-1140, 2015

• DOI for Human islet distribution programme for basic research: activity over the last 5 years

Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Part of Cell Transplantation, p. 263-276, 2015

• DOI for Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Graft function 1 year after pregnancy in an islet-transplanted patient

Schive, Simen W.; Scholz, Hanne; Sahraoui, Afaf; Kloster-Jensen, Kristine et al.

Part of Transplant International, p. 1235-1239, 2015

• DOI for Graft function 1 year after pregnancy in an islet-transplanted patient

Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets invitro

Kloster-Jensen, Kristine; Vethe, Nils Tore; Bremer, Sara; Abadpour, Shadab et al.

Part of Transplant International, p. 1152-1161, 2015

• DOI for Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets invitro

Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Wiberg, Anna; Granstam, Anna; Ingvast, Sofie; Harkonen, T. et al.

Part of Clinical and Experimental Immunology, p. 278-288, 2015

• DOI for Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Proof Of Concept For The Clinical Application Of Animal Component Free Recombinant Collagenase For Isolating Pancreatic Islets

Goto, Masafumi; Friberg, Andrew; Ståhle, Magnus; Imura, Takehiro et al.

Part of Transplantation, 2015

Preserved Beta-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells

Carlsson, Per-Ola; Schwarcz, Erik; Korsgren, Olle; Le Blanc, Katarina

Part of Diabetes, p. 587-592, 2015

• DOI for Preserved Beta-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells

Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Frisk, Gun et al.

Part of Diabetes, p. 1682-1687, 2015

• DOI for Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Synthesis and biological evaluation of [C-11]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver

Jahan, M.; Johnstrom, P.; Nag, S.; Takano, A. et al.

Part of Nuclear Medicine and Biology, p. 387-394, 2015

• DOI for Synthesis and biological evaluation of [C-11]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver

Mesenchymal Stromal Cells to Halt the Progression of Type 1 Diabetes?

Carlsson, Per-Ola; Korsgren, Olle; Le Blanc, Katarina

Part of Current Diabetes Reports, 2015

• DOI for Mesenchymal Stromal Cells to Halt the Progression of Type 1 Diabetes?

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Krogvold, Lars; Skog, Oskar; Sundström, Görel; Edwin, Bjorn et al.

Part of Diabetes, p. 2506-2512, 2015

• DOI for Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Identification of potential circulating beta cell biomarkers

Hansson, S. F.; Vachet, P.; Hammar, M.; Korsgren, Olle et al.

Part of Diabetologia, 2015

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

Simonson, Oscar E.; Mougiakakos, Dimitrios; Heldring, Nina; Bassi, Giulio et al.

Part of Stem Cells Translational Medicine, p. 1199-1213, 2015

• DOI for In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

Proof of concept for the clinical application of animal component free recombinant collagenase for isolating pancreatic islets

Goto, Masafumi; Friberg, Andrew; Ståhle, Magnus; Imura, Takehiro et al.

Part of Xenotransplantation, 2015

Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model

Fransson, Moa; Brännström, Johan; Duprez, Ida; Essand, Magnus et al.

Part of Regenerative Medicine Research, 2015

• DOI for Mesenchymal stromal cells supportendothelial cell interactions in anintramuscular islet transplantation model
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Strategical steering of the immune system: induction of leukocyte vascular chaperoning increases functional blood flow responses in ischemic muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Part of The FASEB Journal, 2014

Increased Inflammatory Response in Cytomegalovirus Seropositive Patients with Alzheimer's Disease

Westman, Gabriel; Berglund, David; Widen, Johan; Ingelsson, Martin et al.

Part of PLOS ONE, 2014

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Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

Skog, Oskar; Ingvast, Sofie; Korsgren, Olle

Part of Journal of Clinical Virology, p. 242-247, 2014

• DOI for Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

Gene expression analysis of human islets in a subject at onset of type 1 diabetes

Hopfgarten, Johan; Stenwall, Per-Anton; Wiberg, Anna; Anagandula, Mahesh et al.

Part of Acta Diabetologica, p. 199-204, 2014

• DOI for Gene expression analysis of human islets in a subject at onset of type 1 diabetes

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?

Hansson, Sara F; Korsgren, Stella; Pontén, Fredrik; Korsgren, Olle

Part of Diabetologia, p. 645-646, 2014

• DOI for Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?

Detection of metastatic insulinoma by positron emission tomography with [68Ga]Exendin-4-a case report

Eriksson, B.; Eriksson, O.; Velikyan, Irina; Selvaraju, R. et al.

Part of Wiener Klinische Wochenschrift, 2014

The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling

Danielsson, Angelika; Ponten, Fredrik; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of PLOS ONE, 2014

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Anakinra and Tocilizumab Enhance Survival and Function of Human Islets During Culture: Implications for Clinical Islet Transplantation

Sahraoui, Afaf; Kloster-Jensen, Kristine; Ueland, Thor; Korsgren, Olle et al.

Part of Cell Transplantation, p. 1199-1211, 2014

• DOI for Anakinra and Tocilizumab Enhance Survival and Function of Human Islets During Culture: Implications for Clinical Islet Transplantation

Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma

Selvaraju, Ram Kumar; Velikyan, Irina; Asplund, Veronika; Johansson, Lars et al.

Part of Nuclear Medicine and Biology, p. 471-476, 2014

• DOI for Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma

Quantitative Imaging of Serotonergic Biosynthesis and Degradation in the Endocrine Pancreas

Eriksson, Olof; Selvaraju, Ram K; Johansson, Lars; Eriksson, Jan W et al.

Part of Journal of Nuclear Medicine, p. 460-465, 2014

• DOI for Quantitative Imaging of Serotonergic Biosynthesis and Degradation in the Endocrine Pancreas

Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system

Hulspas, Ruud; Villa-Komaroff, Lydia; Koksal, Erin; Etienne, Kenol et al.

Part of Cytotherapy, p. 1384-1389, 2014

• DOI for Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system

The Positron Emission Tomography ligand [11C]5-Hydroxy-Tryptophan can be used as a surrogate marker for the human endocrine pancreas

Eriksson, Olof; Espes, Daniel; Selvaraju, Ram K; Jansson, Emma et al.

Part of Diabetes, p. 3428-3437, 2014

• DOI for The Positron Emission Tomography ligand [11C]5-Hydroxy-Tryptophan can be used as a surrogate marker for the human endocrine pancreas

Engineering Regulatory Cells With a T Cell Receptor for Controlled Activation

Hillerdal, Victoria; Berglund, David; Boura, Vanessa; Jin, Chuan et al.

Part of Molecular Therapy, 2014

Detection of Metastatic Insulinoma by Positron Emission Tomography with [(68)Ga]Exendin-4 -: a case report

Eriksson, Olof; Velikyan, Irina; Selvaraju, Ram K; Kandeel, Fouad et al.

Part of Journal of Clinical Endocrinology and Metabolism, p. 1519-1524, 2014

• DOI for Detection of Metastatic Insulinoma by Positron Emission Tomography with [(68)Ga]Exendin-4 -: a case report

Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study

Krogvold, Lars; Edwin, Bjorn; Buanes, Trond; Ludvigsson, Johnny et al.

Part of Diabetologia, p. 841-843, 2014

• DOI for Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study

Completion of the First FDA Phase 3 Multicenter Trial of Islet Transplantation in Type 1 Diabetes by the NIH CIT Consortium

Ricordi, C.; Hering, B.; Bridges, N.; Eggerman, T. et al.

Part of Cytotherapy, 2014

• DOI for Completion of the First FDA Phase 3 Multicenter Trial of Islet Transplantation in Type 1 Diabetes by the NIH CIT Consortium

Utilization of Small Pediatric Donors Including Infants for Pancreas and Kidney Transplantation: Exemplification of the Surgical Technique and the Surveillance

Biglarnia, Ali-Reza; Bennet, William; Nilsson, Thomas; Larsson, Erik et al.

Part of Annals of Surgery, 2014

• DOI for Utilization of Small Pediatric Donors Including Infants for Pancreas and Kidney Transplantation: Exemplification of the Surgical Technique and the Surveillance

PET imaging of the GLP-1 receptor in healthy and streptozotocin-induced diabetic pigs

Selvaraju, Ram Kumar; Nalin, Lovisa; Velikyan, Irina; Berglund, Marie et al.

Part of Journal of Nuclear Medicine, p. 387, 2014

Endovascular Method for Transplantation of Insulin-Producing Cells to the Pancreas Parenchyma in Swine

Lundberg, J.; Stone-Elander, S.; Zhang, X. -M; Korsgren, Olle et al.

Part of American Journal of Transplantation, p. 694-700, 2014

• DOI for Endovascular Method for Transplantation of Insulin-Producing Cells to the Pancreas Parenchyma in Swine
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Infection of Human Islets of Langerhans With Two Strains of Coxsackie B Virus Serotype 1: Assessment of Virus Replication, Degree of Cell Death and Induction of Genes Involved in the Innate Immunity Pathway

Anagandula, Mahesh; Richardson, Sarah J.; Oberste, M. Steven; Sioofy-Khojine, Amir-Babak et al.

Part of Journal of Medical Virology, p. 1402-1411, 2014

• DOI for Infection of Human Islets of Langerhans With Two Strains of Coxsackie B Virus Serotype 1: Assessment of Virus Replication, Degree of Cell Death and Induction of Genes Involved in the Innate Immunity Pathway

Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs

Nalin, Lovisa; Selvaraju, Ram K; Velikyan, Irina; Berglund, Marie et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 1800-1810, 2014

• DOI for Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs

Positron Emission Tomography imaging of the glucagon like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs

Selvaraju, Ram Kumar; Nalin, L.; Velikyan, Irina; Berglund, Marie et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2014

Cytomegalovirus-Specific CD4 and CD8 T Cell Responses in Infants and Children

Lidehäll, Anna Karin; Engman, Mona-Lisa; Sund, Fredrik; Malm, Gunilla et al.

Part of Scandinavian Journal of Immunology, p. 135-143, 2013

• DOI for Cytomegalovirus-Specific CD4 and CD8 T Cell Responses in Infants and Children

Human Islet Isolation Processing Times Shortened by One Hour: No Incubation Between Tissue Harvest and Isopycnic Islet Purification

Friberg, Andrew S.; Ståhle, Magnus; Honkanen-Scott, Minna; Ingvast, Sofie et al.

Part of Transplantation, 2013

Tropism Analysis of Two Coxsackie B5 Strains Reveals Virus Growth in Human Primary Pancreatic Islets but not in Exocrine Cell Clusters In Vitro

Hodik, Monika; Lukinius, Agneta; Korsgren, Olle; Frisk, Gun

Part of Open Virology Journal, p. 49-56, 2013

• DOI for Tropism Analysis of Two Coxsackie B5 Strains Reveals Virus Growth in Human Primary Pancreatic Islets but not in Exocrine Cell Clusters In Vitro

Ga-68-labelling of Exendin-4, preclinical evaluation of the resultant tracer for the imaging and quantification of insulinomas, and case patient examination

Velikyan, Irina; Selvaraju, K. Ram; Sörensen, Jens; Kandeel, Fouad et al.

Part of Journal of labelled compounds & radiopharmaceuticals, 2013

Human Islet Isolation Processing Times Shortened By One Hour: Minimized Incubation Time Between Tissue Harvest and Islet Purification

Ståhle, Magnus; Honkanen-Scott, Minna; Ingvast, Sofie; Korsgren, Olle et al.

Part of Transplantation, 2013

• DOI for Human Islet Isolation Processing Times Shortened By One Hour: Minimized Incubation Time Between Tissue Harvest and Islet Purification

Preliminary Results From Evaluation of an Innovative, Closed, Automated, Continuous Media Renewal System for Human Islets of Langerhans

Ståhle, Magnus; Friberg, Andrew; Ingvast, Sofie; Honkanen-Scott, Minna et al.

Part of Transplantation, 2013

Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer's Disease

Westman, Gabriel; Lidehall, Anna-Karin; Magnusson, Peetra; Ingelsson, Martin et al.

Part of PLOS ONE, 2013

• DOI for Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer's Disease
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Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures

Yu, Di; Jin, Chuan; Ramachandran, Mohanraj; Xu, Jing et al.

Part of PLOS ONE, 2013

• DOI for Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
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Imaging the in vivo fate of human T cells following transplantation in immunoincompetent mice - Implications for clinical cell therapy trials

Berglund, David; Karlsson, Marie; Palanisamy, Senthilkumar; Carlsson, Björn et al.

Part of Transplant Immunology, p. 105-108, 2013

• DOI for Imaging the in vivo fate of human T cells following transplantation in immunoincompetent mice - Implications for clinical cell therapy trials

Human Pancreatic Islet Preparations Release HMGB1: (Ir)Relevance for Graft Engraftment

Nano, Rita; Racanicchi, Leda; Melzi, Raffaella; Mercalli, Alessia et al.

Part of Cell Transplantation, p. 2175-2186, 2013

• DOI for Human Pancreatic Islet Preparations Release HMGB1: (Ir)Relevance for Graft Engraftment

The diagnosis of insulitis in human type 1 diabetes

Campbell-Thompson, M. L.; Atkinson, M. A.; Butler, A. E.; Chapman, N. M. et al.

Part of Diabetologia, p. 2541-2543, 2013

• DOI for The diagnosis of insulitis in human type 1 diabetes

Obtaining regulatory T cells from uraemic patients awaiting kidney transplantation for use in clinical trials

Berglund, David; Karlsson, Marie; Biglarnia, Ali-Reza; Lorant, Tomas et al.

Part of Clinical and Experimental Immunology, p. 310-322, 2013

• DOI for Obtaining regulatory T cells from uraemic patients awaiting kidney transplantation for use in clinical trials

Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Molnár, Christian; Essand, Magnus; Wennberg, Lars; Berne, Christian et al.

Part of Cell Transplantation, p. 243-251, 2013

• DOI for Islet Engraftment and Revascularization in Clinical and Experimental Transplantation

Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins

Hansson, Sara F.; Korsgren, Stella; Pontén, Fredrik; Korsgren, Olle

Part of Journal of Pathology, p. 719-728, 2013

• DOI for Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins

A Vast Amount of Enzyme Activity Fails to Be Absorbed Within the Human Pancreas: Implications for Cost-Effective Islet Isolation Procedures

Friberg, Andrew S.; Korsgren, Olle; Hellgren, Mikko

Part of Transplantation, 2013

• DOI for A Vast Amount of Enzyme Activity Fails to Be Absorbed Within the Human Pancreas: Implications for Cost-Effective Islet Isolation Procedures

Induction of an Antiviral State and Attenuated Coxsackievirus Replication in Type III Interferon-Treated Primary Human Pancreatic Islets

Lind, Katharina; Richardson, Sarah J.; Leete, Pia; Morgan, Noel G. et al.

Part of Journal of Virology, p. 7646-7654, 2013

• DOI for Induction of an Antiviral State and Attenuated Coxsackievirus Replication in Type III Interferon-Treated Primary Human Pancreatic Islets

In Vivo Imaging of the Glucagonlike Peptide 1 Receptor in the Pancreas with Ga-68-Labeled DO3A-Exendin-4

Selvaraju, Ram K.; Velikyan, Irina; Johansson, Lars; Wu, Zhanhong et al.

Part of Journal of Nuclear Medicine, p. 1458-1463, 2013

• DOI for In Vivo Imaging of the Glucagonlike Peptide 1 Receptor in the Pancreas with Ga-68-Labeled DO3A-Exendin-4

Quality of Isolated Pig Islets Is Improved Using Perfluorohexyloctane for Pancreas Storage in a Split Lobe Model

Brandhorst, H.; Iken, M.; Scott, W. E. ; Papas, K. K. et al.

Part of Cell Transplantation, p. 1477-1483, 2013

• DOI for Quality of Isolated Pig Islets Is Improved Using Perfluorohexyloctane for Pancreas Storage in a Split Lobe Model
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Treatment Efficacy and Immune Stimulation by AdCD40L Gene Therapy of Spontaneous Canine Malignant Melanoma

Westberg, Sara; Sadeghi, Arian; Svensson, Emma; Segall, Thomas et al.

Part of Journal of immunotherapy (1997), p. 350-358, 2013

• DOI for Treatment Efficacy and Immune Stimulation by AdCD40L Gene Therapy of Spontaneous Canine Malignant Melanoma

Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion

Vågesjö, Evalina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Part of European Journal of Clinical Investigation, p. 27-27, 2013

Assessing the Viability of Human Pancreas Grafts using 31P MR Spectroscopy - a Pilot Study

Sjöberg, Lina; Biglarnia, Alireza; Ahlström, Håkan; Korsgren, Olle et al.

Part of Transplantation, 2013

Neural Crest Stem Cells Induce Beta-cell Proliferation in Cultured and Transplanted Human Pancreatic Islets

Grapensparr, Liza; Vasylovska, Svitlana; Olerud, Johan; Korsgren, Olle et al.

Part of Transplantation, 2013

Commercial Enzymes for Islet Isolation: Integrity and Degradation Over Time and Temperature

Ståhle, Magnus; Friberg, Andrew; Korsgren, Olle

Part of Transplantation, 2013

Functional Imaging of the Pancreatic Graft by Positron Emission Tomography

Eriksson, Olof; Sjöberg, Lina; Ahlström, Håkan; Antoni, Gunnar et al.

Part of Transplantation, 2013

Expanding the Donor Pool in Islet Transplantation: Age Impacts Parameters Regulating Glucose Metabolism

Sahraoui, Afaf; Hoeyem, Merete; Winzell, Maria Soerhede; Smith, Dave et al.

Part of Transplantation, 2013

In Human Islets the Intracellular Concentration of Sirolimus Diminish when Combined with Tacrolimus, In Vitro.

Kloster-Jensen, Kristine; Vethe, Nils Tore; Bremer, Sara; Foss, Aksel et al.

Part of Transplantation, 2013

Human islet isolation processing times shortened by one hour: minimized incubation time between tissue harvest and islet purification

Ståhle, Magnus; Honkanen-Scott, Minna; Ingvast, Sofie; Korsgren, Olle et al.

Part of Transplantation, 2013

• DOI for Human islet isolation processing times shortened by one hour: minimized incubation time between tissue harvest and islet purification

On the etiology of type 1 diabetes: A new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response

Korsgren, Stella; Molin, Ylva; Salmela, K.; Lundgren, T. et al.

Part of American Journal of Pathology, p. 1735-1748, 2012

• DOI for On the etiology of type 1 diabetes: A new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response

Transplanted functional islet mass: donor islet preparation, and recipitent factors influence early graft function in islet-after-kidney patients

Friberg, Andrew S.; Lundgren, Torbjörn; Malm, Helene; Felldin, M et al.

Part of Transplantation, p. 632-638, 2012

• DOI for Transplanted functional islet mass: donor islet preparation, and recipitent factors influence early graft function in islet-after-kidney patients

Using HTK for Prolonged Pancreas Preservation Prior to Human Islet Isolation

Caballero-Corbalán, José; Brandhorst, Heide; Malm, Helene; Felldin, Marie et al.

Part of Journal of Surgical Research, p. 163-168, 2012

• DOI for Using HTK for Prolonged Pancreas Preservation Prior to Human Islet Isolation

Oxygen-charged HTK-F6H8 emulsion reduces ischemia: reperfusion injury in kidneys from brain-dead pigs

Asif, Sana; Sedigh, Amir; Nordström, Johan; Brandhorst, Heide et al.

Part of Journal of Surgical Research, p. 959-967, 2012

• DOI for Oxygen-charged HTK-F6H8 emulsion reduces ischemia: reperfusion injury in kidneys from brain-dead pigs

Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?

Moll, Guido; Rasmusson-Duprez, Ida; von Bahr, Lena; Connolly-Andersen, Anne-Marie et al.

Part of Stem Cells, p. 1565-1574, 2012

• DOI for Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?

Preclinical evaluation of a ⁶⁸Ga-labeled biotin analogue for applications in islet transplantation

Eriksson, Olof; Carlsson, Fredrik; Blom, Elisabeth; Sundin, Anders et al.

Part of Nuclear Medicine and Biology, p. 415-421, 2012

• DOI for Preclinical evaluation of a ⁶⁸Ga-labeled biotin analogue for applications in islet transplantation

Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation

Berglund, David; Korsgren, Olle; Lorant, Tomas; Schneider, Karin et al.

Part of Transplant Immunology, p. 27-33, 2012

• DOI for Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation

Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts

Westermark, Gunilla T.; Davalli, Alberto M.; Secchi, Antonio; Folli, Franco et al.

Part of Transplantation, p. 219-223, 2012

• DOI for Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts

Pancreatic uptake of [68Ga]DO3A-Exendin4 is mediated by the GLP-1 receptor

Selvaraju, Ram Kumar; Velikyan, Irina; Espes, Daniel; Carlsson, Per-Ola et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2012

Insulin independence after conversion from tacrolimus to cyclosporine in islet transplantation

von Zur-Mühlen, Bengt; Tufveson, Gunnar; Korsgren, Olle

Part of Transplant International, 2012

• DOI for Insulin independence after conversion from tacrolimus to cyclosporine in islet transplantation

Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction

Ylipaasto, P.; Smura, T.; Gopalacharyulu, P.; Paananen, A. et al.

Part of Diabetologia, p. 3273-3283, 2012

• DOI for Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction

A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets

Taneera, Jalal; Lang, Stefan; Sharma, Amitabh; Fadista, Joao et al.

Part of Cell Metabolism, p. 122-134, 2012

• DOI for A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets

gamma-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

Taneera, J.; Jin, Zhe; Jin, Yang; Muhammed, S. J. et al.

Part of Diabetologia, p. 1985-1994, 2012

• DOI for gamma-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates

Lindskog, Cecilia; Korsgren, Olle; Pontén, Fredrik; Eriksson, Jan W et al.

Part of Journal of Proteomics, p. 2611-2620, 2012

• DOI for Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates

Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms

Banerjee, Meenal; Virtanen, Ismo; Palgi, Jaan; Korsgren, Olle et al.

Part of Molecular and Cellular Endocrinology, p. 78-86, 2012

• DOI for Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms

Decreased defluorination using the novel beta-cell imaging agent [¹⁸F]FE-DTBZ-d4 in pigs examined by PET

Jahan, Mahabuba; Eriksson, Olof; Johnström, Peter; Korsgren, Olle et al.

Part of EJNMMI Research, p. 33, 2011

• DOI for Decreased defluorination using the novel beta-cell imaging agent [¹⁸F]FE-DTBZ-d4 in pigs examined by PET

Syngeneic islet transplantation into the submandibular gland of mice

Sandberg, Monica; Carlsson, Fredrik; Nilsson, Bo; Korsgren, Olle et al.

Part of Transplantation, 2011

• DOI for Syngeneic islet transplantation into the submandibular gland of mice

Syngeneic islet transplantations into the submandibular gland of mice

Sandberg, Monica; Carlsson, Fredrik; Nilsson, Bo; Korsgren, Olle et al.

Part of Transplantation, 2011

• DOI for Syngeneic islet transplantations into the submandibular gland of mice

Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography

Eriksson, Olof; Sadeghi, Arian; Carlsson, Björn; Eich, Torsten et al.

Part of Nuclear Medicine and Biology, p. 827-833, 2011

• DOI for Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography

Large-scale bioreactor expansion of tumor-infiltrating lymphocytes

Sadeghi, Arian; Pauler, Linnea; Annerén, Cecilia; Friberg, Andrew et al.

Part of JIM - Journal of Immunological Methods, p. 94-100, 2011

• DOI for Large-scale bioreactor expansion of tumor-infiltrating lymphocytes

Long-term engraftment and function of transplanted pancreatic islets in vascularized segments of small intestine

Kakabadze, Zurab; Gupta, Sanjeev; Brandhorst, Daniel; Korsgren, Olle et al.

Part of Transplant International, p. 175-183, 2011

• DOI for Long-term engraftment and function of transplanted pancreatic islets in vascularized segments of small intestine

Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig

Purins, Karlis; Sedigh, Amir; Molnar, Christian; Jansson, Leif et al.

Part of Critical Care Medicine, p. 512-517, 2011

• DOI for Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig

Pathogen Inactivation of Human Serum Facilitates its Clinical Use for Islet Cell Culture and Subsequent Transplantation

Ståhle, Magnus U.; Brandhorst, Daniel; Korsgren, Olle; Knutson, Folke

Part of Cell Transplantation, p. 775-781, 2011

• DOI for Pathogen Inactivation of Human Serum Facilitates its Clinical Use for Islet Cell Culture and Subsequent Transplantation
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Quantification of the Islet Product: Presentation of a Standardized Current Good Manufacturing Practices Compliant System With Minimal Variability

Friberg, Andrew S.; Brandhorst, Heide; Buchwald, Peter; Goto, Masafumi et al.

Part of Transplantation, p. 677-683, 2011

• DOI for Quantification of the Islet Product: Presentation of a Standardized Current Good Manufacturing Practices Compliant System With Minimal Variability

The Instant Blood-Mediated Inflammatory Reaction Characterized in Hepatocyte Transplantation

Gustafson, Elisabet K.; Elgue, Graciela; Hughes, Robin D.; Mitry, Ragai R. et al.

Part of Transplantation, p. 632-638, 2011

• DOI for The Instant Blood-Mediated Inflammatory Reaction Characterized in Hepatocyte Transplantation

Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

Nilsson, Bo; Nilsson Ekdahl, Kristina; Korsgren, Olle

Part of Current Opinion in Organ Transplantation, p. 620-626, 2011

• DOI for Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation

Duprez, Ida Rasmusson; Johansson, Ulrika; Nilsson, Bo; Korsgren, Olle et al.

Part of Upsala Journal of Medical Sciences, p. 8-17, 2011

• DOI for Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation

Modulation of Innate Immunity in Human Pancreatic Islets Infected With Enterovirus In Vitro

Skog, Oskar; Korsgren, Olle; Frisk, Gun

Part of Journal of Medical Virology, p. 658-664, 2011

• DOI for Modulation of Innate Immunity in Human Pancreatic Islets Infected With Enterovirus In Vitro

CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study

Sund, Fredrik; Lidehäll, Anna Karin; Claesson, Kerstin; Foss, Aksel et al.

Part of Clinical Transplantation, p. 401-409, 2010

• DOI for CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study

Resolvin E1 Reduces Proinflammatory Markers in Human Pancreatic Islets in vitro

Lund, T.; Mangsbo, Sara M.; Scholz, H.; Gjorstrup, P. et al.

Part of Experimental and clinical endocrinology & diabetes, p. 237-244, 2010

• DOI for Resolvin E1 Reduces Proinflammatory Markers in Human Pancreatic Islets in vitro

Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle: Establishment of a Vascular System Similar to that in Native Islets

Christoffersson, Gustaf; Henriksnäs, Johanna; Johansson, Lars; Rolny, Charlotte et al.

Part of Diabetes, p. 2569-2578, 2010

• DOI for Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle: Establishment of a Vascular System Similar to that in Native Islets

CART is upregulated in islets of type 2 diabetic patients, stimulates insulin secretion, inhibits glucagon secretion and protects against beta cell death

Sathanoori, R.; Voss, U.; Riva, M.; Winzell, M. S. et al.

Part of Diabetologia, 2010

Cocaine- and amphetamine-regulated transcript (CART) is upregulated in islets of type-2 diabetic patients to stimulate insulin secretion, inhibit glucagon secretion and protect against beta cell death

Sathanoori, Ramasri; Voss, Ulrikke; Riva, Matteo; Sorhede-Winzell, M. et al.

Part of Regulatory Peptides, p. 45-45, 2010

• DOI for Cocaine- and amphetamine-regulated transcript (CART) is upregulated in islets of type-2 diabetic patients to stimulate insulin secretion, inhibit glucagon secretion and protect against beta cell death

Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2(-/-)gc(-/-) Mice

Jacobson, S.; Heuts, F.; Juarez, J.; Hultcrantz, M. et al.

Part of Scandinavian Journal of Immunology, p. 83-90, 2010

• DOI for Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2(-/-)gc(-/-) Mice

Coxsackievirus B3 induces the mRNA expression of IFNbeta and viral recognition receptors in human pancreatic islets

Lind, K.; Larsson, P. G.; Huhn, M.; Korsgren, Olle et al.

Part of Diabetologia, 2010

Large-Scale Comparison of Liberase HI and Collagenase NB1 Utilized for Human Islet Isolation

Brandhorst, Heide; Friberg, Andrew; Nilsson, Bo; Andersson, H. H. et al.

Part of Cell Transplantation, p. 3-8, 2010

• DOI for Large-Scale Comparison of Liberase HI and Collagenase NB1 Utilized for Human Islet Isolation

Photochemical pathogen inactivation of human serum enables its large-scale application in clinical cell transplantation

Ståhle, Magnus; Carlsson, B.; Le Blanc, K.; Korsgren, Olle et al.

Part of Vox Sanguinis, 2010

• DOI for Photochemical pathogen inactivation of human serum enables its large-scale application in clinical cell transplantation

In vivo and in vitro characterization of [¹⁸F]-FE-(+)-DTBZ as a tracer for beta-cell mass

Eriksson, Olof; Jahan, Mahabuba; Johnström, Peter; Korsgren, Olle et al.

Part of Nuclear Medicine and Biology, p. 357-363, 2010

• DOI for In vivo and in vitro characterization of [¹⁸F]-FE-(+)-DTBZ as a tracer for beta-cell mass

Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis

Cabric, Sanja; Sanchez, Javier; Johansson, Ulrika; Larsson, Rolf et al.

Part of Tissue engineering. Part A, p. 961-970, 2010

• DOI for Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis

Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success

Koh, Angela; Senior, Peter; Salam, Abdul; Kin, Tatsuya et al.

Part of Transplantation, p. 465-471, 2010

• DOI for Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success

Sustained Reversal of Diabetes Following Islet Transplantation to Striated Musculature in the Rat

Lund, Tormod; Korsgren, Olle; Aursnes, Ingrid A; Scholz, Hanne et al.

Part of Journal of Surgical Research, p. 145-154, 2010

• DOI for Sustained Reversal of Diabetes Following Islet Transplantation to Striated Musculature in the Rat

A new oxygen carrier for improved long-term storage of human pancreata before islet isolation

Brandhorst, Heide; Asif, Sana; Andersson, Karin; Theisinger, Bastian et al.

Part of Transplantation, p. 155-60, 2010

• DOI for A new oxygen carrier for improved long-term storage of human pancreata before islet isolation

The Effect of Truncated Collagenase Class I Isomers on Human Islet Isolation Outcome

Brandhorst, Heide; Asif, Sana; Andersson, Karin; Moench, Johanna et al.

Part of Transplantation, p. 334-335, 2010

• DOI for The Effect of Truncated Collagenase Class I Isomers on Human Islet Isolation Outcome

Mammalian Tissue-Free Liberase: A New GMP-Graded Enzyme Blend for Human Islet Isolation

Caballero-Corbalan, José; Brandhorst, Heide; Asif, Sana; Korsgren, Olle et al.

Part of Transplantation, p. 332-333, 2010

• DOI for Mammalian Tissue-Free Liberase: A New GMP-Graded Enzyme Blend for Human Islet Isolation

Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets

Lindskog, Cecilia; Asplund, Anna; Engkvist, Margareta; Pontén, Fredrik et al.

Part of Discovery Medicine, p. 565-578, 2010

Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism

Jensen-Waern, M.; Andersson, M.; Kruse, R.; Nilsson, Bo et al.

Part of Laboratory Animals, p. 249-254, 2009

• DOI for Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism

Positron emission tomography in clinical islet transplantation

Eriksson, Olof; Eich, Torsten; Sundin, Anders; Tibell, Annika et al.

Part of American Journal of Transplantation, p. 2816-2824, 2009

• DOI for Positron emission tomography in clinical islet transplantation

Vitacyte Collagenase HA: A Novel Enzyme Blend for Efficient Human Islet Isolation

Caballero-Corbalán, José; Friberg, Andrew S.; Brandhorst, Heide; Nilsson, Bo et al.

Part of Transplantation, p. 1400-1402, 2009

• DOI for Vitacyte Collagenase HA: A Novel Enzyme Blend for Efficient Human Islet Isolation

Current Advances and Travails in Islet Transplantation

Harlan, David M.; Kenyon, Norma Sue; Korsgren, Olle; Roep, Bart O.

Part of Diabetes, p. 2175-2184, 2009

• DOI for Current Advances and Travails in Islet Transplantation

The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation

Brandhorst, Heide; Friberg, Andrew; Andersson, Helena H.; Felldin, Maria et al.

Part of Transplantation, p. 370-5, 2009

• DOI for The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation

Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

Moëll, Annika; Skog, Oskar; Åhlin, Erik; Korsgren, Olle et al.

Part of Journal of Medical Virology, p. 1082-1087, 2009

• DOI for Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro

Scholz, Hanne; Lund, Tormod; Dahle, M.K.; Collins, J.L. et al.

Part of Diabetologia, p. 1352-62, 2009

• DOI for The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro

Perfluorohexyloctane improves long-term storage of rat pancreata for subsequent islet isolation

Brandhorst, Heide; Theisinger, Bastian; Yamaya, Hideyuki; Henriksnäs, Johanna et al.

Part of Transplant International, p. 1017-1022, 2009

• DOI for Perfluorohexyloctane improves long-term storage of rat pancreata for subsequent islet isolation

Pig Pancreas Oxygenation at 20°C Increases Islet ATP Generation but Deteriorates Islet Function

Iken, M.; Brandhorst, Heide; Korsgren, Olle; Brandhorst, Daniel

Part of Cell Transplantation, p. 745-751, 2009

• DOI for Pig Pancreas Oxygenation at 20°C Increases Islet ATP Generation but Deteriorates Islet Function
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Low molecular weight dextran sulfate is well tolerated in humans and increases endogenous expression of islet protective hepatocyte growth factor

Schmidt, Peter; Magnusson, Caroline; Lundgren, Torbjörn; Korsgren, Olle et al.

Part of Transplantation, p. 1523-1530, 2008

• DOI for Low molecular weight dextran sulfate is well tolerated in humans and increases endogenous expression of islet protective hepatocyte growth factor

Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation

Goto, Masafumi; Tjernberg, Jenny; Dufrane, Denis; Elgue, Graciela et al.

Part of Xenotransplantation, p. 225-234, 2008

• DOI for Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation

Human islet separation utilizing a closed automated purification system

Friberg, Andrew S.; Ståhle, Magnus; Brandhorst, Heide; Korsgren, Olle et al.

Part of Cell Transplantation, p. 1305-1313, 2008

• DOI for Human islet separation utilizing a closed automated purification system

Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation

Tjernberg, Jenny; Ekdahl, Kristina N.; Lambris, John D.; Korsgren, Olle et al.

Part of Transplantation, p. 1193-1199, 2008

• DOI for Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation

Intramuscular autotransplantation of pancreatic islets in a 7-year-old child: a 2-year follow-up

Rafael, Ehab; Tibell, A.; Rydén, M.; Lundgren, T. et al.

Part of American Journal of Transplantation, p. 458-62, 2008

• DOI for Intramuscular autotransplantation of pancreatic islets in a 7-year-old child: a 2-year follow-up

New class of oxygen carriers improves islet isolation from long-term stored rat pancreata

Brandhorst, Heide; Muehling, B; Yamaya, H; Henriksnäs, Johanna et al.

Part of Transplantation Proceedings, p. 393-394, 2008

• DOI for New class of oxygen carriers improves islet isolation from long-term stored rat pancreata

Degraded collagenase deteriorates islet viability

Brandhorst, Heide; Raemsch-Guenther, N.; Raemsch, C.; Friedrich, O. et al.

Part of Transplantation Proceedings, p. 370-371, 2008

• DOI for Degraded collagenase deteriorates islet viability

Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma

von Euler, Henrik; Sadeghi, Arian; Carlsson, Björn; Rivera, Patricio et al.

Part of Journal of immunotherapy (1997), p. 377-384, 2008

• DOI for Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma

A new method for incorporating functional heparin onto the surface of islets of Langerhans

Cabric, Sanja; Eich, Torsten; Sanchez, Javier; Nilsson, Bo et al.

Part of Tissue Engineering. Part C, Methods, p. 141-147, 2008

• DOI for A new method for incorporating functional heparin onto the surface of islets of Langerhans

Unique basement membrane structure of human pancreatic islets: implications for beta-cell growth and differentiation

Otonkoski, Timo; Banerjee, M.; Korsgren, Olle; Thornell, L-E. et al.

Part of Diabetes, obesity and metabolism, p. 119-27, 2008

• DOI for Unique basement membrane structure of human pancreatic islets: implications for beta-cell growth and differentiation

Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation

Spirig, Rolf; Gajanayake, Thusitha; Korsgren, Olle; Nilsson, Bo et al.

Part of Molecular Immunology, p. 4084-4094, 2008

• DOI for Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation

Blood vessels of human islets of Langerhans are surrounded by a double basement membrane

Virtanen, Ismo; Banerjee, M; Palgi, J; Korsgren, Olle et al.

Part of Diabetologia, p. 1181-91, 2008

• DOI for Blood vessels of human islets of Langerhans are surrounded by a double basement membrane

Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization

Johansson, Ulrika; Rasmusson, Ida; Niclou, Simone P.; Forslund, Naomi et al.

Part of Diabetes, p. 2393-2401, 2008

• DOI for Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization
• Download full text (pdf) of Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization

Optimising islet engraftment is critical for successful clinical islet transplantation

Korsgren, Olle; Lundgren, Torbjörn; Felldin, Marie; Foss, Aksel et al.

Part of Diabetologia, p. 227-32, 2008

• DOI for Optimising islet engraftment is critical for successful clinical islet transplantation

Glucocorticoids reduce pro-inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo

Lund, Tormod; Fosby, Bjarte; Korsgren, Olle; Scholz, Hanne et al.

Part of Transplant International, p. 669-678, 2008

• DOI for Glucocorticoids reduce pro-inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo

The ratio between collagenase class I and class II influences the efficient islet release from the rat pancreas

Brandhorst, Heide; Raemsch-Guenther, Nicole; Raemsch, Christian; Friedrich, Olaf et al.

Part of Transplantation, p. 456-61, 2008

• DOI for The ratio between collagenase class I and class II influences the efficient islet release from the rat pancreas

Islet Surface Heparinization Prevents the Instant-Blood Mediated Inflammatory Reaction in Islet Transplantation

Cabric, Sanja; Sanchez, Javier; Lundgren, Torbjörn; Foss, Aksel et al.

Part of Diabetes, p. 2008-2015, 2007

• DOI for Islet Surface Heparinization Prevents the Instant-Blood Mediated Inflammatory Reaction in Islet Transplantation

Positron emission tomography: A real-time tool to quantify early islet engraftment in a preclinical large animal model

Eich, Torsten; Eriksson, Olof; Sundin, Anders; Estrada, Sergio et al.

Part of Transplantation, p. 893-898, 2007

• DOI for Positron emission tomography: A real-time tool to quantify early islet engraftment in a preclinical large animal model

Interferons induce an antiviral state in human pancreatic islet cells

Hultcrantz, Monica; Hühn, Michael H.; Wolf, Monika; Olsson, Annika et al.

Part of Virology, p. 92-101, 2007

• DOI for Interferons induce an antiviral state in human pancreatic islet cells

Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes

Elshebani, Asma; Olsson, Annika; Westman, Jan; Tuvemo, Torsten et al.

Part of Virus Research, p. 193-203, 2007

• DOI for Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes

Antiviral Treatment of Coxsackie B Virus Infection in Human Pancreatic Islets

Berg, Anna-Karin; Olsson, Annika; Korsgren, Olle; Frisk, Gun

Part of Antiviral Research, p. 65-71, 2007

• DOI for Antiviral Treatment of Coxsackie B Virus Infection in Human Pancreatic Islets

Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells

Gao, R.; Ustinov, J.; Korsgren, Olle; Otonkoski, Timo

Part of American Journal of Transplantation, p. 1021-1026, 2007

• DOI for Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells

No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation

Caballero-Corbalán, José; Eich, Torsten; Lundgren, Torbjörn; Foss, Aksel et al.

Part of Transplantation, p. 864-869, 2007

• DOI for No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation

Maturation of in vitro-generated human islets after transplantation in nude mice

Gao, Ru; Ustinov, Jarkko; Korsgren, Olle; Mikkola, Milla et al.

Part of Molecular and Cellular Endocrinology, p. 28-34, 2007

• DOI for Maturation of in vitro-generated human islets after transplantation in nude mice

Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation

Johansson, H.; Goto, M.; Dufrane, D.; Siegbahn, Agneta et al.

Part of American Journal of Transplantation, p. 305-12, 2006

• DOI for Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation

Lymphocyte propagation from biopsies of kidney allografts

Engstrand, Mats; Larsson, Erik; Naghibi, Mansour; Tufveson, Gunnar et al.

Part of Transplant Immunology, p. 215-219, 2006

• DOI for Lymphocyte propagation from biopsies of kidney allografts

Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome in clinical islet transplantation

Johansson, Helena; Lukinius, Agneta; Moberg, Lisa; Lundgren, Torbjörn et al.

Part of Diabetes, p. 1755-62, 2005

• DOI for Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome in clinical islet transplantation

Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

Johansson, Helena; Lukinius, Agneta; Moberg, Lisa; Lundgren, Torbjörn et al.

Part of Diabetes, p. 1755-62, 2005

• DOI for Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

T cell control of primary and latent cytomegalovirus infections in healthy subjects

Lidehäll, Anna Karin; Sund, Fredrik; Lundberg, Tobias; Eriksson, Britt-Marie et al.

Part of Journal of Clinical Immunology, p. 473-481, 2005

• DOI for T cell control of primary and latent cytomegalovirus infections in healthy subjects

Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period

Schmidt, Peter; Forsman, Anna; Andersson, Göran; Blomberg, Jonas et al.

Part of Xenotransplantation, p. 450-456, 2005

• DOI for Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period

Key factors for human islet isolation and clinical transplantation.

Goto, M; Johansson, U; Eich, T M; Lundgrem, T et al.

Part of Transplant Proc, p. 1315-6, 2005

Technical improvement of human pancreatic islet isolation.

Goto, M; Eich, T M; Stahle, M; Malmborg, A et al.

Part of Transplant Proc, p. 1313-4, 2005

The efficacy of CD40 ligand blockade in discordant pig-to-rat islet xenotransplantation is correlated with an immunosuppressive effect of immunoglobulin.

Wennberg, Lars; Goto, Masafumi; Maeda, Akira; Song, Zhensung et al.

Part of Transplantation, p. 157-64, 2005

Composite islet-endothelial cell grafts: a novel approach to counteract innate immunity in islet transplantation.

Johansson, Ulrika; Elgue, Graciela; Nilsson, Bo; Korsgren, Olle

Part of Am J Transplant, p. 2632-9, 2005

Neutrophilic granulocytes are the predominant cell type infiltrating pancreatic islets in contact with ABO-compatible blood.

Moberg, L; Korsgren, O; Nilsson, B

Part of Clin Exp Immunol, p. 125-31, 2005

The recent finding that tissue factor is produced by the pancreatic islets constitutes a possible link between insulin resistance and cardiovascular disease.

Nilsson, Bo; Berne, Christian; Korsgren, Olle

Part of Am J Ther, p. 551-554, 2005

Current status of clinical islet transplantation.

Korsgren, Olle; Nilsson, B; Berne, Christian; Felldin, M et al.

Part of Transplantation, p. 1289-1293, 2005

Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans.

Olsson, Annika; Johansson, Ulrika; Korsgren, Olle; Frisk, Gun

Part of Biochem Biophys Res Commun, p. 571-6, 2005

• DOI for Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans.

Adenovirus CD40 Ligand Gene Therapy Counteracts Immune Escape Mechanisms in the Tumor Microenvironment

Loskog, Angelica; Dzojic, Helena; Vikman, Sofia; Ninalga, Christina et al.

Part of Journal of Immunology, p. 7200-7205, 2004

MyD88-dependent toll-like receptor signalling is not a requirement for fetal islet xenograft rejection in mice

Schmidt, Peter; Krook, Henrik; Goto, Masafumi; Korsgren, Olle

Part of Xenotransplantation, p. 347-352, 2004

• DOI for MyD88-dependent toll-like receptor signalling is not a requirement for fetal islet xenograft rejection in mice

Intraportal pig islet xenotransplantation into athymic mice as an in vivomodel for the study of the instant blood-mediated inflammatory reaction.

Goto, Masafumi; Groth, CG; Nilsson, Bo; Korsgren, Olle

Part of Xenotransplantation, p. 195, 2004

Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet culture

Goto, Masafumi; Eich, Torsten; Felldin, M; Foss, A et al.

Part of Transplantation, p. 1367-1375, 2004

Importance of the Gal alpha1-3 Gal antigen in discordant islet xenotransplantation: immunosuppression, which inhibits porcine islet xenograft rejection in ordinary mice, is equally effective in Gal-knockout mice.

Wennberg, L; Song, Z; Bennet, W; Sandberg, J O et al.

Part of Transplantation, p. 1275-80, 2004

Intracerebral cytokine profiles in adult rats grafted with neural tissue of different immunological disparity.

Mirza, Bilal; Krook, Henrik; Andersson, Per; Larsson, Lena C et al.

Part of Brain Res Bull, p. 105-18, 2004

[Replacement therapy with beta-cells: the way to treat diabetes in the future?]

Otonkoski, Timo; Korsgren, Olle; Salmela, Kaija

Part of Duodecim, p. 1133-4, 2004

Possible transmission of zoonoses in xenotransplantation: porcine endogenous retroviruses (PERVs) from an immunological point of view

Schmidt, Peter; Andersson, Göran; Blomberg, Jonas; Malmsten, Anders et al.

Part of Acta veterinaria Scandinavica. Supplementum, p. 27-34, 2004

Cellular responses to cytomegalovirus in immunosuppressed patients: circulating CD8⁺ T cells recognizing CMVpp65 are present but display functional impairment

Engstrand, Mats; Lidehäll, Anna Karin; Tötterman, Thomas H.; Herrmann, Björn et al.

Part of Clinical and Experimental Immunology, p. 96-104, 2003

• DOI for Cellular responses to cytomegalovirus in immunosuppressed patients: circulating CD8⁺ T cells recognizing CMVpp65 are present but display functional impairment

Intragraft cytokine mRNA expression in rejecting and non-rejecting Vascularised Xenografts

Lorant, Tomas; Krook, Henrik; Wilton, Jacob; Olausson, Michael et al.

Part of Xenotransplantation, p. 311-324, 2003

• DOI for Intragraft cytokine mRNA expression in rejecting and non-rejecting Vascularised Xenografts

Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture.

Gao, Ru; Ustinov, Jarkko; Pulkkinen, Mari-Anne; Lundin, Karolina et al.

Part of Diabetes, p. 2007-15, 2003

Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation.

Moberg, Lisa; Olsson, Annika; Berne, Christian; Felldin, Marie et al.

Part of Transplantation, p. 1285-8, 2003

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

Moberg, Lisa; Johansson, Helena; Lukinius, Agneta; Berne, Christian et al.

Part of The Lancet, p. 2039-45, 2002

• DOI for Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation.

Moberg, Lisa; Ekdahl, Kristina Nilsson; Elgue, Graciela; Larsson, Rolf et al.

Part of Diabetes, p. 1779-84, 2002

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation.

Moberg, Lisa; Johansson, Helena; Lukinius, Agneta; Berne, Christian et al.

Part of Lancet, p. 2039, 2002

Immunosuppressive drugs in islet xenotransplantation: A tool for gaining further insights in the mechanisms of the rejection process

Krook, Henrik; Wennberg, Lars; Hagberg, Anette; Song, Zhenshung et al.

Part of Transplantation, p. 1084-1089, 2002

A distinct Th1 immune response precedes the described Th2 response in Islet xenograft rejection

Krook, Henrik; Hagberg, Anette; Song, Zhenshung; Landegren, Ulf et al.

Part of Diabetes, p. 79-86, 2002

• DOI for A distinct Th1 immune response precedes the described Th2 response in Islet xenograft rejection

Quantification of lymphocytes propagating from rat-kidney allografts--a tool to monitor anti-rejection treatment.

Engstrand, Mats; Johnsson, Cecilia; Larsson, Erik; Tufveson, Gunnar et al.

Part of Transpl Immunol, p. 31-6, 2002

C-Peptide determinations in islet xenotransplantation: A study in the pig-to-mouse model.

Wennberg, L; Sundberg, B; Nilsson Ekdahl, Kristina; Korsgren, Olle

Part of Cell Transplant., p. 165, 2001

A new in vitro model for the study of pig-to human vascular hyperacute rejection.

Bennet, W; Wundberg, B; Elgue, Graciela; Larsson, Rolf et al.

Part of Xentotransplantation, p. 176, 2001

Expression of complement regulatory proteins on islets of Langerhans: a comparison between human islet and islets isolated from normal and hDAF transgenic pigs.

Bennet, W; Björkland, Anna; Sundberg, B; Brandhorst, D et al.

Part of Transplantation, p. 312, 2001

Soluble complement receptor 1 (TP10) preserves adult porcine islet morphology after intraportal transplantation into cynomolgus monkeys

Lundgren, T; Bennet, W; Tibell, A; Söderlund, J et al.

Part of Transplant Proc., p. 725, 2001

Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

Markmann, James F.; Bartlett, Stephen T.; Johnson, Paul; Korsgren, Olle et al.

Part of Transplantation, 2016

• DOI for Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of beta-Cell Replacement

Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

Skog, Oskar; Korsgren, Stella; Melhus, Åsa; Korsgren, Olle

Part of Current Opinion In Endocrinology Diabetes And Obesity, p. 118-123, 2013

• DOI for Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

Nilsson, Bo; Korsgren, Olle; Lambris, John D.; Ekdahl, Kristina Nilsson

Part of Trends in immunology, p. 32-38, 2010

• DOI for Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes

Korsgren, Olle; Nilsson, Bo

Part of Current Opinion in Organ Transplantation, p. 683-687, 2009

• DOI for Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes

Co-transplantation of human and pig islets

Korsgren, Olle; Groth, Carl G

Part of Xenotransplantation, p. 112-112, 2008

• DOI for Co-transplantation of human and pig islets

Proceedings of "Pig-to-Man Islet Transplant Summit" held at the Nobel Forum, Stockholm, June 4-5, 2007

Groth, Carl G; Korsgren, Olle

Part of Xenotransplantation, p. 77-78, 2008

• DOI for Proceedings of "Pig-to-Man Islet Transplant Summit" held at the Nobel Forum, Stockholm, June 4-5, 2007

Treating diabetes with islet transplantation: Lessons learnt from the Nordic network for clinical islet transplantation

von Zur-Mühlen, Bengt; Scholz, Hanne; Hellman, Jarl; Korsgren, Olle et al.

Part of Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, p. 599-611, Academic Press, 2019

• DOI for Treating diabetes with islet transplantation: Lessons learnt from the Nordic network for clinical islet transplantation

Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo.

Goto, Masafumi; Johansson, Helena; Maeda, Akira; Elgue, Graciela et al.

2004

Evaluation of the new pancreas preservation solution, I-Let Protect, for clinical islet isolation and transplantation

Ståhle, Magnus; Foss, Aksel; Gustafsson, Bengt; Lempinen, Marko et al.

2015

Uncovering a new role for immune cells: macrophages assist in regulation of blood flow in ischemic muscle

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Korsgren, Olle et al.

Expression of Coxsackie and Adenovirus Receptor in islets of Langerhans from Type 1 diabetes, islet autoantibody positive and non-diabetic subjects

Hodik, Monika; Anagandula, Mahesh; Krogvold, Lars; Dahl-Jorgensen, Knut et al.

Enterovirus Infection Reduces Beta-cell Function and Leads to Decreased Glucose Stimulated Insulin Secretion in Dissociated but not In Intact Pancreatic Human Islets

Skog, Oskar; Hodik, Monika; Korsgren, Olle; Frisk, Gun

Ongoing Pathogenic Processes in the Pancreas at Onset of Type 1 Diabetes in Humans

Skog, Oskar; Hodik, Monika; Lukinius, Agneta; Korsgren, Olle et al.

Positron Emission Tomography imaging of CD69 in a murine model of rheumatoid arthritis

Puuvuori, Emmi; Shen, Yunbing; Hulsart Billström, Gry; Mitran, Bogdan et al.

Preclinical evaluation of Affibody molecule ¹⁸F-TZ-Z_AM106 for PET imaging of DGCR2

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Lead compound identification from first-in-class high affinity Affibody molecules binders towards DGCR2

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Khalil, Amina et al.